Bone scintigraphy is widely used to diagnose bone diseases. Accurate hotspot segmentation is a critical task for tumor metastasis diagnosis. In this paper, we propose an interactive approach to detect and extract hots...
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ISBN:
(纸本)9781479999897
Bone scintigraphy is widely used to diagnose bone diseases. Accurate hotspot segmentation is a critical task for tumor metastasis diagnosis. In this paper, we propose an interactive approach to detect and extract hotspots in thoracic region based on a new multiple instance learning (MIL) method called EM-MILBoost. We convert the segmentation problem to a multiple instance learning task by constructing positive and negative bags according to the input bounding box. In order to be robust against noisy input, we train a region-level hotspot classifier with EM-MILBoost and develop several segmentation strategies based on it. The experimental results demonstrate that our method outperforms other methods and is robust against various noisy input.
Non-small cell lung cancer (NSCLC) is a malignant tumor, and contains three major subtypes which are difficult to be distinguished at early stages of NSCLC. Many pathways work together to perform certain functions in ...
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ISBN:
(纸本)9781509016129
Non-small cell lung cancer (NSCLC) is a malignant tumor, and contains three major subtypes which are difficult to be distinguished at early stages of NSCLC. Many pathways work together to perform certain functions in cells. One might expect the high level of co-appearance or repression of pathways to distinguish different subtypes of NSCLC. However, it is difficult to detect coordinated regulations of pathways by existing methods. In our work, the coordinated regulations of pathways are detected using modified higher logic analysis of gene expression data. Specifically, we identify the genes whose regulation obeys a logic function by the modified higher logic analysis, which focuses on the relationships among the gene triplets that are not evident when genes are examined in a pairwise fashion. Then, the relationships among genes are mapped to pathways to predict the coordinated regulated relationships among pathways. By comparing coordinated regulations of pathways, we find that the regulation patterns of pathways which are associated with cell death are different in three subtypes of NSCLC. This method allows us to uncover co-appearance or repression of pathways in high level, and it has a potential to distinguish the subtypes for complex diseases.
An assignment-driven multi-consensus problem of multi-agent systems with heterogeneous delays is investigated in this paper. By introducing a concept of intelligent adjustment factor, a distributed impulsive protocol ...
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ISBN:
(纸本)9781509017393
An assignment-driven multi-consensus problem of multi-agent systems with heterogeneous delays is investigated in this paper. By introducing a concept of intelligent adjustment factor, a distributed impulsive protocol is designed, in which only the delayed sampled relative positions to neighbors and the relative position to the last sampling state are utilized. Combined with the characteristic of impulsive control, three steps of model transformation are performed, and the assignment-driven multi-consensus problem of the original continuous-time system is converted to the stability problem of a discrete-time expanded analogous error system. A necessary and sufficient criterion is derived to guarantee the assignment-driven multi-consensus of the multi-agent system. An interesting simulation is proposed to demonstrate the effectiveness of the theoretical result and reveal the effect of intelligent adjustment factors on the assignment-driven multi-consensus.
With the rapid development of computer network, multimedia technology has gradually spread throughout all aspects of people's life. This article, based on the concept and characteristics of multimedia, expounds th...
With the rapid development of computer network, multimedia technology has gradually spread throughout all aspects of people's life. This article, based on the concept and characteristics of multimedia, expounds the application of multimedia technology and the trend of future development. It makes a heavy analysis of multimedia teaching and analyses the meaning and advantage of multimedia teaching.
Based on the idea of 'q—count' of certain subwords of a word and generalizing the notion of Parikh matrix of a word, the notion of Parikh q—matrix of a word over an ordered alphabet was introduced. On the ot...
Based on the idea of 'q—count' of certain subwords of a word and generalizing the notion of Parikh matrix of a word, the notion of Parikh q—matrix of a word over an ordered alphabet was introduced. On the other hand, with a two-dimensional picture array of symbols arranged in rows and columns, two kinds of upper triangular matrices, known as row and column Parikh matrices have also been introduced and investigated. Here combining these two kinds of matrices of a picture array, we introduce row/column Parikh q—matrix of an array, leading to the concept of q—ambiguity of a picture array. Results relating to q—ambiguity of picture arrays are derived in the context of these Parikh q—matrices of arrays.
Radiomics aims to extract and analyze large numbers of quantitative features from medical images and is highly promising in staging, diagnosing, and predicting outcomes of cancer treatments. Nevertheless, several chal...
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Cyber-physical systems(CPSs) are integrations of networks, computation and physical processes, where embedded computing devices continually sense, monitor, and control the physical processes through networks. Networke...
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Cyber-physical systems(CPSs) are integrations of networks, computation and physical processes, where embedded computing devices continually sense, monitor, and control the physical processes through networks. Networked industrial processes combining internet, real-time computer control systems and industrial processes together are typical CPSs. With the increasingly frequent cyber-attack, security issues have gradually become key problems for CPSs. In this paper, a cyber-physical system security protection approach for networked industrial processes, i.e., industrial CPSs, is proposed. In this approach, attacks are handled layer by layer from general information technology(IT) security protection, to active protection, then to intrusion tolerance and physical security protection. The intrusion tolerance implemented in real-time control systems is the most critical layer because the real time control system directly affects the physical layer. This novel intrusion tolerance scheme with a closed loop defense framework takes into account the special requirements of industrial CPSs. To illustrate the effectiveness of the CPS security protection approach, a networked water level control system is described as a case study in the architecture analysis and design language(AADL) environment. Simulation results show that 3 types of injected attacks can be quickly defended by using the proposed protection approach.
Brain Magnetic Resonance image(MRI) plays a non-substitutive role in clinical *** symptom of many diseases corresponds to the structural variants of *** structure segmentation in brain MRI is of great importance in mo...
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ISBN:
(纸本)9781509009107
Brain Magnetic Resonance image(MRI) plays a non-substitutive role in clinical *** symptom of many diseases corresponds to the structural variants of *** structure segmentation in brain MRI is of great importance in modern medical *** methods were developed for automatic segmenting of brain MRI but failed to achieve desired *** this paper,we proposed a new patch-based approach for automatic segmentation of brain MRI using convolutional neural network(CNN).Each brain MRI acquired from a small portion of public dataset is firstly divided into *** of these patches are then used for training CNN,which is used for automatic segmentation of brain *** results showed that our approach achieved better segmentation accuracy compared with other deep learning methods.
Bus driver rostering is a world-wide problem, which is NP-hard. Two objectives exist in the problem: (1) minimizing the number of drivers;(2) minimizing excess workload of each driver and balancing excess workload amo...
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