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Inside Cover: A novel in vivo Cerenkov luminescence image-guided surgery on primary and metastatic colorectal cancer (J. Biophotonics 3/2020)

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Journal of Biophotonics 2020年第3期13卷

作者： Zeyu Zhang Yawei Qu Yu Cao Xiaojing Shi Hongbo Guo Xiaojun Zhang Sheng Zheng Haifeng Liu Zhenhua Hu Jie Tian Engineering Research Center of Molecular and Neuro Imaging of Ministry of Education School of Life Science and Technology Xidian University Xi'an China CAS Key Laboratory of Molecular Imaging Beijing Key Laboratory of Molecular Imaging The State Key Laboratory of Management and Control for Complex Systems Institute of Automation Chinese Academy of Sciences Beijing China Department of Gastroenterology the Third Medical Centre Chinese PLA General Hospital Beijing China Department of Control Science and Engineering Harbin Institute of Technology Harbin China Department of Anorectal the Third medical Centre Chinese PLA General Hospital Beijing China University of Chinese Academy of Sciences Beijing China School of Information Sciences and Technology Northwest University Xi'an China Department of Nuclear Medicine Chinese PLA General Hospital Beijing China Beijing Advanced Innovation Center for Big Data-Based Precision Medicine School of Medicine Beihang University Beijing China

This study presents a novel intraoperative in vivo imaging approach which harnessed Cerenkov luminescence (CL) to detect primary and metastatic colorectal cancer (CRC) using clinically approved radiopharmaceuticals. In the mice and swine experiments, the proposed approach effectively improved the effect of CRC surgery. The approach is believed to be promising for utilizing CL in open surgery. Further details can be found in the article by Zeyu Zhang, Yawei Qu, Yu Cao et al. ( e201960152 )

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Submillimeter Papillae: Shape control of Lotus Leaf Induced by Surface Submillimeter Texture (Adv. Mater. Interfaces 8/2020)

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Advanced Materials Interfaces 2020年第8期7卷

作者： Peiliu Li Lei Wang Shousheng Tang Yan Xing Hongbin Zhao Jing Liu Biomechanics and Biomaterials Laboratory Department of Applied Mechanics School of Aerospace Engineering Beijing Institute of Technology Beijing 100081 P. R. China Beijing Key Laboratory of Cryo‐Biomedical Engineering CAS Key Laboratory of Cryogenics Technical Institute of Physics and Chemistry Chinese Academy of Sciences Beijing 100190 P. R. China School of Astronautics ShenYuan Honors College Beihang University Beijing 100191 P. R. China State Key Laboratory of Advanced Materials for Smart Sensing General Research Institute for Nonferrous Metals Beijing 100088 P. R. China Department of Biomedical Engineering School of Medicine Tsinghua University Beijing 100084 China

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Publisher Correction: A vaccine targeting the RBD of the S protein of SARS-CoV-2 induces protective immunity

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Nature 2021年第7844期590卷 E23页

作者： Jingyun Yang Wei Wang Zimin Chen Shuaiyao Lu Fanli Yang Zhenfei Bi Linlin Bao Fei Mo Xue Li Yong Huang Weiqi Hong Yun Yang Yuan Zhao Fei Ye Sheng Lin Wei Deng Hua Chen Hong Lei Ziqi Zhang Min Luo Hong Gao Yue Zheng Yanqiu Gong Xiaohua Jiang Yanfeng Xu Qi Lv Dan Li Manni Wang Fengdi Li Shunyi Wang Guanpeng Wang Pin Yu Yajin Qu Li Yang Hongxin Deng Aiping Tong Jiong Li Zhenling Wang Jinliang Yang Guobo Shen Zhiwei Zhao Yuhua Li Jingwen Luo Hongqi Liu Wenhai Yu Mengli Yang Jingwen Xu Junbin Wang Haiyan Li Haixuan Wang Dexuan Kuang Panpan Lin Zhengtao Hu Wei Guo Wei Cheng Yanlin He Xiangrong Song Chong Chen Zhihong Xue Shaohua Yao Lu Chen Xuelei Ma Siyuan Chen Maling Gou Weijin Huang Youchun Wang Changfa Fan Zhixin Tian Ming Shi Fu-Sheng Wang Lunzhi Dai Min Wu Gen Li Guangyu Wang Yong Peng Zhiyong Qian Canhua Huang Johnson Yiu-Nam Lau Zhenglin Yang Yuquan Wei Xiaobo Cen Xiaozhong Peng Chuan Qin Kang Zhang Guangwen Lu Xiawei Wei Laboratory of Aging Research and Cancer Drug Target State Key Laboratory of Biotherapy and Cancer Center National Clinical Research Center for Geriatrics West China Hospital Sichuan University Chengdu China. National Kunming High-level Biosafety Primate Research Center Institute of Medical Biology Chinese Academy of Medical Sciences and Peking Union Medical College Yunnan China. Key Laboratory of Human Disease Comparative Medicine Chinese Ministry of Health Beijing Key Laboratory for Animal Models of Emerging and Remerging Infectious Diseases Institute of Laboratory Animal Science Chinese Academy of Medical Sciences and Comparative Medicine Center Peking Union Medical College Beijing China. National Institutes for Food and Drug Control (NIFDC) Beijing China. National Chengdu Center for Safety Evaluation of Drugs State Key Laboratory of Biotherapy and Cancer Center West China Hospital Sichuan University Collaborative Innovation Center for Biotherapy Chengdu China. Shanghai Key Laboratory of Chemical Assessment and Sustainability School of Chemical Science & Engineering Tongji University Shanghai China. Treatment and Research Center for Infectious Diseases The Fifth Medical Center of PLA General Hospital National Clinical Research Center for Infectious Diseases Beijing China. Center for Biomedicine and Innovations Faculty of Medicine Macau University of Science and Technology Macau China. Department of Computer Science and Technology Tsinghua University Beijing China. Department of Applied Biology and Chemical Technology Hong Kong Polytechnic University Hong Kong China. Sichuan Provincial Key Laboratory for Human Disease Gene Study and Institute of Laboratory Medicine Sichuan Provincial People's Hospital University of Electronic Science and Technology of China Chengdu China. State Key Laboratory of Medical Molecular Biology Chinese Academy of Medical Sciences School of Basic Medicine Peking Union Medical College Beijing China. Center for Biomedicine and Innovation

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Expressions of the Cell Cycle Relative Proteins in Esophageal Cancer Tissues

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Journal of Cancer Therapy 2018年第11期9卷 857-871页

作者： Sara Khodahemmati Jintao Li Hongwei Liu Maliha Ghaffar Yangjunqi Wang Zhixiang Zhou Yi Zeng Beijing Key Laboratory of Environmental and Viral Oncology College of Life Science and Bio-Engineering Beijing University of Technology Beijing China Department of Life Science China West Normal University Nanchong China State Key Laboratory of Infectious Disease Prevention and Control National Institute for Viral Disease Control and Prevention Chinese Center for Disease Control and Prevention Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases Beijing China

The aim of the research is to investigate the expression of the cell cycle relative proteins (P53, P16, Cyclin D1, and Ki67) in Esophageal Cancer (EC) patients of the Chaoshan area, China. In China, Chaoshan has the high incidence of EC. Different areas have shown different rate for expression of these proteins in EC. We investigated the expression of p53, p16, cyclinD1, and ki67 for the first time in Chaoshan. In this research, DNA was extracted from formalin fixed and paraffin embedded tissues of esophageal cancer (EC) patients. The expression level of proteins cycle was detected by using immunohistochemistry (IHC). And the data was checked by χ2 test or Fisher’s exact test of SPSS17.0. The positive immunohistochemical staining of p53, p16, cyclinD1, and ki67 were observed in 65.7% 39.2%, 69.1%, and 83.5% specimens respectively. There was a positive correlation between p53 positive staining and p16, cyclinD1, ki67 staining at p < 0.05. CyclinD1 has the high correlation with ki67 at p < 0.05. A significant inverse correlation was considered between the expression of p16 and cyclinD1 and there was no correlation observed between p16 and ki67. In Conclusion, this study demonstrated the high expression of p53, Cyclin D1 and Ki67 and low expression of P16 and the association of these cell cycle relative proteins in esophageal cancer are new data in Chaoshan area of China. Geographical distribution of EC on the molecular basis is revealed in this research.

关键词： Esophageal Cancer Regulatory Pathway P53 P16 CyclinD1 ki67

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Research on Fault Diagnosis of Power Transformer Equipment Based on KNN Algorithm

Research on Fault Diagnosis of Power Transformer Equipment B...

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International Conference on mechatronics and Intelligent Robotics, ICMIR 2017

作者： Yu, Huadong Wu, Qing Lu, Yongling Hu, Chengbo Wang, Yubo Liu, Guohua State Grid Information and Communication Industry Group Beijing100031 China State Grid Jiangsu Electric Power Company Research Institute Nanjing211103 China State Grid Key Laboratory of Power Industrial Chip Design and Analysis Technology Beijing Smart-Chip Microelectronics Technology Co. Ltd. Beijing100192 China Beijing Engineering Research Center of High-Reliability IC with Power Industrial Grade Beijing Smart-Chip Microelectronics Technology Co. Ltd. Beijing100192 China

ISBN: (纸本)9783319709895

Power equipment is of great importance to the power of things, the operation of equipment directly impact on the safety and stability of the power of things. Therefore, it is important to ensure secure and stable operation of the power grid by prejudging monitoring, observing and fault diagnosis of power equipment. A fault diagnosis method of power equipment based on the technology of power internet of things and KNN algorithm is proposed in this paper. Through the real-time sensing and data acquisition of the basic equipment status in power network operation, the equipment status is analyzed and prejudged, which can provide alarm signals of the equipment to avoid greater security risk. © 2018, Springer International Publishing AG.

关键词： Failure analysis

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Analytical Compliance Modeling of Serial Flexure-Based Compliant Mechanism Under Arbitrary Applied Load

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Chinese Journal of Mechanical engineering 2017年第4期30卷 951-962页

作者： Li-Ping Wang Yao Jiang Tie-Min Li Institute of Manufacturing Engineering Department of MechanicalTsinghua UniversityBeijing 100084China Beijing Key Laboratory of Precision/Ultra-Precision Manufacturing Equipments and Control Tsinghua UniversityBeijing 100084China Institute of Instrument Science and Technology Department of Precision InstrumentTsinghua UniversityBeijing 100084China

Analytical compliance model is vital to the flexure- based compliant mechanism in its mechanical design and motion control. The matrix is a common and effective approach in the compliance modeling while it is not well developed for the closed-loop serial and parallel compliant mechanisms and is not applicable to the situation when the external loads are applied on the flexure mem- bers. Concise and explicit analytical compliance models of the serial flexure-based compliant mechanisms under arbitrary loads are derived by using the matrix method. An equivalent method is proposed to deal with the situation when the external loads are applied on the flexure mem- bers. The external loads are transformed to concentrated forces applied on the rigid links, which satisfy the equa- tions of static equilibrium and also guarantee that the deformations at the displacement output point remain unchanged. Then the matrix method can be still adopted for the compliance analysis of the compliant mechanism. Finally, several specific examples and an experimental testare given to verify the effectiveness of the compliance models and the force equivalent method. The research enriches the matrix method and provides concise analytical compliance models for the serial compliant mechanism.

关键词： Compliant mechanism Compliancemodeling Matrix method

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Impedance control with New Inner Torque loop for Compliant Joints and Its Performance Analysis 36

Impedance Control with New Inner Torque loop for Compliant J...

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第36届中国控制会议

作者： Yin Ke Jian Li Zonglin Huang Shuai Li Guodong Li The Bionic Robot and System Key Laboratory School of Mechatronic EngineeringBeijing Institute of Technology Key Laboratory for Intelligent Control and Decision on Complex Systems School of AutomationBeijing Institute of Technology Beijing Jingwei Hirain Technologies

ISBN: (纸本)9781538629185

For the purpose of enhancing compliance of robot joint,an impedance control strategy with new inner torque controller is *** inertia of the motor can be scaled down thanks to this new type of torque *** of different position（motor-side position 9 and link-side position q） feedback strategies are explored through theoretical deviation,simulation and static stiffness *** expressions of static stiffness under both position feedback strategies are obtained with validity verified by Simulink *** with 9 feedback strategy,static stiffness can exceed spring stiffness under q feedback strategy with high desired stiffness,which means wider variation range of static stiffness and this benefits robot applications that require wider variation range of impedance,such as rehabilitation robots and collaborative ***,several experiments with the compliant joint prototype verify the developed controllers and show the efficiency of the proposed control approach in terms of compliant behavior.

关键词： Compliant joint Impedance control Static stiffness

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Adaptive Output Feedback Autopilot Design for Spinning Projectiles 36

Adaptive Output Feedback Autopilot Design for Spinning Proje...

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第36届中国控制会议

作者： Zhongjiao Shi Liangyu Zhao School of Aerospace Engineering Beijing Institute of Technology Key Laboratory of Dynamics and Control of Flight Vehicle Ministry of Education

ISBN: (纸本)9781538629185

Design of spinning projectile autopilot is a challenge due to uncertain aerodynamics,and stringent performance *** solve the control challenge for such state inaccessible plant,a robust output feedback adaptive controller is designed for a double-channel controlled spinning projectile in this *** first step towards the solution is the development of the dynamic model for the spinning *** on the model,an output feedback adaptive controller is applied for the autopilot *** a robust compensator is designed and added to the adaptive controller for the *** tests are performed to assess stability and performance of the closed-loop adaptive *** addition,results in simulations indicate the autopilot allows for fast adaptation with high gain adaptive rates,while eliminating high frequency oscillation and guaranteeing transient performance.

关键词： Adaptive control Autopilot Design Output Feedback Spinning Projectile

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The Time-to-go Consensus of Multi-Missiles with Communication Delay 36

The Time-to-go Consensus of Multi-Missiles with Communicatio...

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第36届中国控制会议

作者： Chunyan Zhang Jianmei Song Lan Huang Key Laboratory of Dynamics and Control of Flight Vehicle Ministry of EducationSchool of Aerospace Engineering Beijing Institute of Technology

ISBN: (纸本)9781538629185

In this paper,the multi-missiles cooperative attack problem with communication delay is ***,the cooperative proportional guidance law with communication delay is *** the cooperative guidance system is transformed into a linear time-varying system,whose state variables are the differences of the time-to-go of the ***,by using the Lyapunov theory,the asymptotic stability of the system is proved,that is,the time-to-go consensus of multi-missiles controlled by the proposed cooperative proportional guidance law is ***,the explicit expression of the maximal tolerable delay is ***,the effectiveness of the proposed cooperative proportional guidance law with communication delay is verified by simulation results.

关键词： cooperative attack communication delay time-to-go consensus

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A Practical and Lowcost Calibration Method for MIMU 3

A Practical and Lowcost Calibration Method for MIMU

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2017 3rd IEEE International Conference on control Science and Systems engineering (ICCSSE)

作者： Liu Yukuan Li Chuanjun Wu Jiangxiong Key Laboratory of Dynamics and Control of Flight Vehicle Ministry of Education School of Aerospace Engineering Beijing Institute of Technology

ISBN: (纸本)9781538604854

This paper was performed to find a practical error calibration method for MIMU to overcome the shortcoming of the traditional way. To study it, first, we simplified the error model of the MIMU. The model contains zero bias, scale factors and installation errors of MEMS accelerometer and MEMS gyro. Then, based on the model, we calibrated the accelerometer in use of a practical six-position testing. And in view of the installation error between the turntable and MIMU used in gyro testing, we found a simple method to calibrate the MEMS gyro. The method only need a turntable with one rotation axis. To check the accuracy of the calibration method, for accelerometer, we compared the tilt angle solved by the accelerometer after calibration with the angle before calibration. And for gyro, we compared the output of the gyro after calibration with before. As a result, this method has strength on high precision, easy operation, low cost and strong versatility.

关键词： MIMU calibration practical method MEMS installation error scale factor

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