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Micro/nano flow chemistry by Beyond Limits Manufacturing

Chinese Chemical Letters 2024年第5期35卷 3-12页

作者： Peiwen Liu Fang Zhao Jing Zhang Yunpeng Bai Jinxing Ye Bo Bao Xinggui Zhou Li Zhang Changlu Zhou Xinhai Yu Peng Zuo Jianye Xia Lian Cen Yangyang Yang Guoyue Shi Lin Xu Weiping Zhu Yufang Xu Xuhong Qian State Key Laboratory of Bioreactor Engineering Shanghai Key Laboratory of Chemical BiologySchool of PharmacyEast China University of Science and TechnologyShanghai 200237China State Key Laboratory of Chemical Engineering School of Chemical EngineeringEast China University of Science and TechnologyShanghai 200237China State Key Laboratory of Bioreactor Engineering Shanghai Collaborative Innovation Center for BiomanufacturingEast China University of Science and TechnologyShanghai 200237China School of Biomedical and Pharmaceutical Sciences Guangdong University of TechnologyGuangzhou 510006China School of Mechanical and Power Engineering East China University of Science and TechnologyShanghai 200237China Shanghai Key Laboratory of Green Chemistry and Chemical Processes Department of ChemistrySchool of Chemistry and Molecular EngineeringEast China Normal UniversityShanghai 200241China

In September 2018,we proposed the cutting-edge concept of“Beyond Limits Manufacturing”(BLM).BLM technology is based on the three-dimensional inner engraving or precise outer engraving of ultra-fast laser,to invent micro/nano scale flow chips or devices,which makes it possible for the microform,integration,economy,safety,high efficiency,green and intelligence of research,development and manufacturing process,so as to realize transformational manufacturing in the era of Industry *** this paper,we reviewed the representative results we made in the field of micro/nano flow chemistry during the implementation of the BLM major project(December 2019 to August 2023),and discussed its application prospects in micro/nano flow chemistry.

关键词： Beyond Limits Manufacturing Flow chemistry Pharmaceutical manufacturing Microreactor

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TS-GGNN: Combining Graph and Sequence Features for Vulnerability Detection in Source Code 5

TS-GGNN: Combining Graph and Sequence Features for Vulnerabi...

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5th International Conference on Communications, Information System and Computer engineering, CISCE 2023

作者： Zhou, Xin Pang, Jianmin Zhang, Chunyan Yue, Feng Wang, Junchao Liu, Guangming State Key Laboratory of Mathematical Engineering and Advanced Computing Zhengzhou China

ISBN: (纸本)9798350326796

Software vulnerability detection is crucial for maintaining the security and stability of software systems. In this paper, we propose a novel neural network model called TS-GGNN to address the problem of vulnerability detection in source code slices. The TS-GGNN model effectively captures both local and global features of vulnerable code by fusing sequence features with graph features. To achieve this, we utilize graph structure and sequence structure learning approaches to comprehensively extract valuable information from the source code slices. Our experiments are conducted on the SARD dataset, which consists of 61,638 code samples annotated for the presence or absence of vulnerabilities. The results demonstrate that TS-GGNN has the best vulnerability detection performance, with an accuracy of 99.4%, a precision of 98.81%, and an F1 score as high as 99.4% thereby validating the effectiveness of the TS-GGNN model in capturing features relevant to software vulnerabilities. © 2023 IEEE.

关键词： Network coding

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Enzymatic self-assembly/disassembly turns “ON”/“OFF” the mimetic hydrolytic activity of histidine nanofibers

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science China Chemistry 2024年第2期67卷 517-522页

作者： Xianbao Sun Manli Wang Xiaoyang Liu Wenjun Zhan Guangqiong Xu Qiaochu Jiang Hai-Dong Xu Fuqiang Wang Gaolin Liang State Key Laboratory of Digital Medical Engineering School of Biological Science and Medical EngineeringSoutheast UniversityNanjing210096China Analysis Center Nanjing Medical UniversityNanjing210029China

Mimetic enzymes are devised as alternates or supplements of natural enzymes in broad fields but regulating their activities in a switchable manner remains ***,we proposed an enzymatic self-assembly/disassembly strategy to address this issue.A peptide molecule Nap FFEYIH(YH) was rationally designed which,after self-assembling into nanofibers,lined up the histidine moieties to form active hydrolysis centers for mimicking hydrolase *** dephosphorylation of Nap FFEYp IH(Yp H) by alkaline phosphatase to yield YH also turned “ON” the hydrolase *** turn,phosphorylation of YH by phosphokinase epidermal growth factor receptor to yield Yp H disassembled the nanofibers and thus turned the activity “OFF”.As such,the “ON”/“OFF” of the mimetic hydrolase activities could be regulated under physiological conditions through ALP/EGFR-mediated self-assembly/disassembly of histidine *** work provides a feasible strategy for the on-demand fabrication of artificial enzymes with controllable and superior activities.

关键词： disassembly hydrolytic activity mimetic enzyme phosphorylation self-assembly

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Exogenous L-tryptophan treatment increases the concentrations of melatonin and aroma compounds in grape berries and wine

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Food Quality and Safety 2024年第3期8卷 534-544页

作者： Guangqing Xiang Runpu Jia Fei Wang Shengnan Wang Yifan Li Yuxin Yao State Key Laboratory of Crop Biology Key Laboratory of Biology and Genetic Improvement of Horticultural Crops in Huang-Huai RegionMinistry of AgricultureCollege of Horticulture Science and EngineeringShandong Agricultural UniversityTaianChina

L-Tryptophan(Trp)is a substrate for the biosynthesis of melatonin,and melatonin is a signal molecule that alters the secondary metabolite profile;whether Trp treatments promote the biosynthesis of melatonin to regulate aroma compounds in grape berries and wine remains ***,the content of melatonin was higher in Marselan grapes and wine than that in other grape *** grapes were subjected to 30 different Trp *** content of melatonin and aroma compounds in Marselan grapes was increased by several *** in the content of volatiles were mainly driven by increases in ***,the most abundant aldehyde compound,was the main contributor to increases in aldehydes following Trp *** results of our study indicate that the root application of 250 mg/L L-tryptophan during the fruiting expansion stage and the spraying application of 50 mg/L L-tryptophan spray during the veraison stage were the optimal treatments because the content of melatonin and aroma compounds,as well as other basic quality parameters,were highest in Trp-treated grape berries and wine in these ***,these two effective Trp treatments could be used to enhance the content of melatonin and aroma compounds in Marselan grapes,and this could increase the economic value of this cultivar.

关键词： Marselan grape L-tryptophan melatonin aroma compounds wine

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Skinned Motion Retargeting with Preservation of Body Part Relationships

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IEEE Transactions on Visualization and Computer Graphics 2024年 PP卷 1-13页

作者： Zhang, Jia-Qi Wang, Miao Zhang, Fu-Cheng Zhang, Fang-Lue State Key Laboratory of Virtual Reality Technology and Systems Beihang University Beijing China State Key Laboratory of Virtual Reality Technology and Systems School of Computer Science and Engineering Beihang University Beijing China School of Engineering and Computer Science Victoria University of Wellington New Zealand

Motion retargeting is an active research area in computer graphics and animation, allowing for the transfer of motion from one character to another, thereby creating diverse animated character data. While this technology has numerous applications in animation, games, and movies, current methods often produce unnatural or semantically inconsistent motion when applied to characters with different shapes or joint counts. This is primarily due to a lack of consideration for the geometric and spatial relationships between the body parts of the source and target characters. To tackle this challenge, we introduce a novel spatially-preserving Skinned Motion Retargeting Network (SMRNet) capable of handling motion retargeting for characters with varying shapes and skeletal structures while maintaining semantic consistency. By learning a hybrid representation of the character's skeleton and shape in a rest pose, SMRNet transfers the rotation and root joint position of the source character's motion to the target character through embedded rest pose feature alignment. Additionally, it incorporates a differentiable loss function to further preserve the spatial consistency of body parts between the source and target. Comprehensive quantitative and qualitative evaluations demonstrate the superiority of our approach over existing alternatives, particularly in preserving spatial relationships more effectively IEEE

关键词： Semantics

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Bismuth-free Mg_(3)Sb_(2) with enhanced room-temperature thermoelectric and mechanical properties

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Journal of Materiomics 2024年第5期10卷 1101-1108页

作者： Jie Song Peng Luo Hailong Sun Hezhang Li Chao Wang Yi Niu Jing Jiang Clean Energy Materials and Engineering Center State Key Laboratory of Electronic Thin Films and Integrated DevicesSchool of Electronic Science and EngineeringUniversity of Electronic Science and Technology of ChinaChengdu611731China The State Key Laboratory of Precision Measurement Technology and Instruments Department of Precision InstrumentTsinghua UniversityBeijing100084China

Thermoelectric materials are competitive candidates for special cooling ***_(3)Sb_(2)-based materials consisting of inexpensive ingredients have profound thermoelectric *** present,alloying with Mg_(3)Bi_(2) is the most effective approach to optimize the thermoelectric properties of Mg_(3)Sb_(2)-based ***,the extremely low abundance of bismuth in the crust contradicts its economic *** this work,the ZrO_(2) micro-particles were separated into the Mg_(3.2)Sb_(1.99)Te_(0.01).The doping effect of Zr atoms at Mg sites increased the electrical conductivity,and the combined secondary phase lowered the lattice thermal *** acceptable degradation in the Seebeck coefficient,the sample combined with 5%(in mass)ZrO_(2) exhibited a dimensionless figure of merit(zT)of 0.49 and a power factor of 2.7 mW·m^(−1)·K^(−2) near room *** average zT in the range from 300 K to 500 K reached 0.8,on par with the Mg_(3)Sb_(2) single bond Mg_(3)Bi_(2) ***,the compressive and bending strengths reach 669 MPa and 269 MPa,respectively,far superior to the common room-temperature *** secondary phase showed a surprising and uncostly promotion of the Mg_(3)Sb_(2)-based thermoelectric materials,impelling the realization of its commercial application.

关键词： Mg_(3)Sb_(2)-Mg_(3)Bi_(2)alloy Secondary phase Room-temperature thermoelectric properties Mechanical properties Inexpensive ingredients

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Celebrating 40 Years of Chemical Research in Chinese Universities

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Chemical Research in Chinese Universities 2024年第4期40卷 561-563页

作者： YU Jihong WANG Dan State Key Laboratory of Inorganic Synthesis and Preparative Chemistry International Center of Future ScienceJilin UniversityChangchun 130012P.R.China State Key Laboratory of Biochemical Engineering Key Laboratory of Biopharmaceutical Preparation and DeliveryInstitute of Process EngineeringChinese Academy of SciencesBeijing 100190P.R.China

Chemical Research in Chinese Universities was founded in 1984 as a comprehensive academic journal in the field of *** has since become a repository of intellectual treasures,documenting the evolving landscape of chemical science within the academic *** the past 40 years,Chemical Research in Chinese Universities has witnessed the rapid development of chemical research in universities.

关键词： chemistry. landscape journal

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The development of polymers and fibers: an interview with Stephen Cheng

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National science Review 2024年第10期11卷 159-161页

作者： Wei Yan the State Key Laboratory for Modification of Chemical Fibers and Polymer Materials College of Materials Science and EngineeringDonghua University

Polymer and fiber science has evolved significantly since the 1920s, with polymers becoming integral to both industry and daily life. China's fiber research, initiated in the 1950s, has made substantial societal and technological contributions, particularly in chemical fibers. How will future advancements in polymers and fibers address ongoing challenges and drive further innovation?NSR spoke to Prof. Stephen Cheng, a member of the National Academy of engineering(U.S.) and former Dean of the College of Polymer science and Polymer engineering at the University of Akron. He is currently Dean and Honorable Professor at South China University of Technology. His research interests center on the condensed states in polymers, liquid crystals, surfactants and hybrid materials, focusing on the interactions, responses, dynamics and structures of materials at varying lengths, energy and timescales, in which the material itself embodies the technology.

关键词： development interview with cheng fibers polymers stephen

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Solar manipulations of perpendicular magnetic anisotropy for flexible spintronics

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Frontiers of physics 2024年第4期19卷 73-79页

作者： Zhexi He Yifan Zhao Yujing Du Meng Zhao Yuxuan Jiang Ming Liu Ziyao Zhou State Key Laboratory for Manufacturing Systems Engineering Electronic Materials Research LaboratoryKey Laboratory of the Ministry of Education&International Center for Dielectric ResearchSchool of Electronic Science and EngineeringThe International Joint Laboratory for Micro/Nano Manufacturing and Measurement TechnologyXi’an Jiaotong UniversityXi’an 710049China School of Materials Science&Engineering Changzhou UniversityChangzhou 213164China

Flexible electronics/spintronics attracts researchers’attention for their application potential abroad in wearable devices,healthcare,and other *** devices’performance(speed,energy consumption)is highly dependent on manipulating information bits(spin-orientation in flexible spintronics).In this work,we established an organic photovoltaic(OPV)/ZnO/Pt/Co/Pt heterostructure on flexible PET substrates with perpendicular magnetic anisotropy(PMA).Under sunlight illumination,the photoelectrons generated from the OPV layer transfer into the PMA heterostructure,then they reduce the PMA strength by enhancing the interfacial Rashba field *** coercive field(Hc)reduces from 800 Oe to 500 Oe at its maximum,and the magnetization can be switched up and down *** stability of sunlight control of magnetization reversal under various bending conditions is also tested for flexible spintronic ***,the voltage output of sunlight-driven PMA is achieved in our prototype device,exhibiting an excellent angular dependence and opening a door towards solar-driven flexible spintronics with much lower energy consumption.

关键词： interfacial magnetoelectric coupling perpendicular magnetic anisotropy deterministic magnetization reversal photovoltaic control of magnetism

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A High-Performance Stretchable Triboelectric Nanogenerator Based on Polytetrafluoroethylene(PTFE)Particles

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Energy & Environmental Materials 2025年第1期8卷 246-254页

作者： Jiawei Liu Jinhui Wang Yawen Wang Zhilin Wu Hongbiao Sun Yan Yang Lisheng Zhang Xu Kou Pengyuan Li Wenbin Kang Jiangxin Wang School of Mechanical Engineering Sichuan UniversityChengdu 610065China State Key Laboratory of Environment-Friendly Energy Materials Southwest University of Science and TechnologyMianyang 621010China

Triboelectric nanogenerators(TENGs)are emerging as new technologies to harvest electrical power from mechanical *** the distinctive working mechanism of triboelectric nanogenerators,they attract particular interest in healthcare monitoring,wearable electronics,and deformable energy harvesting,which raises the requirement for highly conformable devices with substantial energy ***,a simple,low-cost strategy for fabricating stretchable triboelectric nanogenerators with ultra-high electrical output is *** TENG is prepared using PTFE micron particles(PPTENG),contributing a different electrostatic induction process compared to TENG based on dielectric films,which was associated with the dynamics of particle motions in *** generator achieved an impressive voltage output of 1000 V with a current of 25 lA over a contact area of 40320 mm^(2).Additionally,the TENG exhibits excellent durability with a stretching strain of 500%,and the electrical output performance does not show any significant degradation even after 3000 cycles at a strain of 400%.The unique design of the device provides high conformability and can be used as a self-powered sensor for human motion detection.

关键词： particles stretchable electronics triboelectric nanogenerators wearable sensors

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