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Associations of chronic exposure to a mixture of pesticides and type 2 diabetes mellitus in a Chinese elderly population

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Chemosphere 2024年 351卷 141194页

作者： Chen, Tian Liu, Xiaohua Zhang, Jianghua Wang, Lulu Su, Jin Jing, Tao Xiao, Ping State Environmental Protection Key Laboratory of the Assessment of Effects of Emerging Pollutants on Environmental and Human Health Shanghai Municipal Center for Disease Control and Prevention Shanghai China Department of Environmental Health Shanghai Municipal Center for Disease Control and Prevention Shanghai China Shanghai Minhang Center for Disease Control and Prevention Shanghai China Key Laboratory of Environment and Health Ministry of Education & Ministry of Environmental Protection and State Key Laboratory of Environmental Health School of Public Health Tongji Medical College Huazhong University of Science and Technology Hubei Wuhan China

Epidemiological studies have related exposure to pesticides to increased risk of diabetes. However, few studies have evaluated the health effects of mixed pesticides exposure, especially in an elderly population. Here, we utilized gas chromatography-tandem mass spectrometry to quantify the levels of 39 pesticides in 4 categories in a Chinese elderly population. Then we used general linear models to explore the association between individual pesticide exposure and type 2 diabetes mellitus (T2DM). Restricted cubic spline (RCS) models were fitted to identify potential non-linearities between those associations. Furthermore, stratified analysis by gender was conducted to explore the gender-specific associations. Finally, we used weighted quantile sum (WQS) regression, quantile-based g computation (qgcomp), and Bayesian kernel machine regression (BKMR) to evaluate the effects of mixed exposure to 39 pesticides. The results showed that exposure to pesticides was associated with high risk of T2DM, with β-Hexachlorocyclohexane (β-BHC) and oxadiazon being the most significant independent contributors, which was pronounced among elderly women. Moreover, the association of β-BHC and oxadiazon with T2DM was linear. These indicated that it is an urgent need to take practical measures to control these harmful pesticides. © 2024 Elsevier Ltd

关键词： Pesticides

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Continuous Commutation Failure Suppression Method Based on Self-adaptive Auto-disturbance Rejection Proportional-integral controller for HVDC Transmission System

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Journal of Modern Power Systems and Clean Energy 2020年第6期8卷 1178-1187页

作者： Tonghua Wu Yuping Zheng Qipu Liu Guoqiang Sun Xiaohong Wang Xindong Li the College of Energy and Electrical Engineering Hohai UniversityNanjing 210098China NARI Group Corporation Nanjing 211106China State Key Laboratory of Smart Grid Protection and Control Nanjing 211106China

Once an asymmetrical fault occurs on the AC side of the receiving-end of a high-voltage direct current(HVDC)transmission system,the current reference will be affected by the control regulation on the DC inverter side and the commutation voltage *** this case,the advance firing angle will fluctuate periodically,causing security threats to the *** the fault cannot be cleared in time,the effect may be even more ***,the traditional proportional-integral(PI)controller cannot effectively suppress the periodic components in the input error signal,which is an important cause of continuous commutation ***,the system requires more time to recover from the *** by this,a selfadaptive auto-disturbance rejection PI controller is proposed in this *** controller has the advantages of fast response speed and strong anti-interference ability of the auto-disturbance rejection *** one hand,it can automatically adjust PI,and the parameters can maintain the system’s adaptive *** the other hand,the discretization process satisfies the computer simulation *** applying the proposed controller to a system under constant current control and extinction angle control,the dynamic response speed can be improved and the robust performance of the system can be ensured when dealing with a wide range of ***,simulation results show that the proposed algorithm can effectively suppress the continuous commutation failure of DC transmission systems.

关键词： High-voltage direct current(HVDC)transmission continuous commutation failure periodic fluctuation self-adaptive auto-disturbance rejection proportional-integral(PI)controller computer simulation

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Regulation of trans-Golgi SNARE proteins recycling by dynamin-like GTPase MoVpsl and retromer in the pathogenicity of rice blast fungus

Regulation of trans-Golgi SNARE proteins recycling by dynami...

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2024年亚洲植物病理学大会

作者： Lili Lin Qiuqiu Wu Xiuwei Huang Qing Gong Aarti Haoyue Yu Shuang Wang Yue Liu Wenhui Zheng State Key Laboratory for Ecological Pest Control of Fujian and Taiwan Crops the School of Life SciencesCollege of Plant ProtectionFujian Agriculture and Forestry University

Rice blast is the most severe disease affecting rice production,posing a significant threat to national food *** upon our prior research,which unveiled a novel protein and membrane trafficking pathway from fungal endolysosomes to the interface of Magnaporthe oryzae-rice interaction,we delved into the functionalities of the MoRab7/Retromer/MoSnc1 sorting apparatus in mediating effector secretion during the biotrophic and invasive growth phases of rice blast fungus.

关键词： Regulation of trans-Golgi SNARE proteins recycling by dynamin-like GTPase MoVpsl and retromer in the pathogenicity of rice blast fungus GTPase

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Gdi Engine Fuel Injection Rate Online Estimation by Improved Zeuch Method

SSRN

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SSRN 2023年

作者： Fu, Yumin Qian, Liyun Ji, Ou Zhang, Haiyan State Environmental Protection Key Laboratory of Vehicle Emission Control and Simulation Chinese Research Academy of Environmental Sciences China

To meet more rigorous economy and emission regulation requirements, high injection pressure, multi-hole injector and split injection strategies are widely used in GDI engines to improve fuel atomization performance. The high injection pressure and split injection shorten single fuel pulse duration and also cause the fuel injector to frequently work in the non-linear region of its flow curve, in which injection rate dispersion is large. The multi-hole design makes it easy for the injector to be fouled and plugged, and its flow curve to be shifted in the vehicle's daily operation. Accordingly, it is necessary to estimate the real fuel injection rate when the engine is running and compensate for its excursion. An online fuel injection rate estimation method is developed in this study. It is based on the improved Zeuch method. During fuel injection, the common rail pressure signal is recorded and employed in a calculus process, by which the fuel mass of each injection pulse is achieved. The calculation result is compared with the measured value from the fuel meter in the engine DYNO test. Fuel pressure and temperature, pressure sensor installation position, high-pressure fuel pump action timing, engine operating condition, and cycle-to-cycle fluctuation are studied to determine their effects on the precision of the fuel injection mass calculation process. Data from engine DYNO show that the calculation error could be less than 5% of the measured value from the fuel meter. This online method is accurate enough for fuel injection rate online monitoring and control. All of the inputs for the method are from sensors on mass-production GDI engines. © 2023, The Authors. All rights reserved.

关键词： Fuel injection

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Regulation performance of virtual synchronous generator applied in renewable energy system

Regulation performance of virtual synchronous generator appl...

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2021 International Conference on Information Technology and Intelligent control, CITIC 2021

作者： Qi, WeiZhi Zha, Daojun Wu, Tonghua Dai, Wei Li, Xindong Hou, Xiaofan State Grid Jiangsu Electric Power Co. Ltd. Nanjing210024 China State Key Laboratory of Smart Grid Protection and Control Nanjing Nanjing 211106 China Nanjing211106 China

The conventional synchronous generator (SG) can regulate the active and reactive power for frequency and voltage stability, when the system fluctuates. In renewable energy generation system (RES), the stability problem of RES can be solved by adding virtual inertia and damping in the control strategy of the grid-connected inverter. The grid-connected inverter and renewable energy system with this kind of control strategy, called as virtual synchronous generator (VSG), acts as a synchronous generator. In this paper, the topology of grid-connected PV array and energy storage system is proposed. The VSG used in grid-connected inverter, is modelled as stator and rotor model by stator voltage equation and rotor motion equation, respectively. Meanwhile, the VSG control mechanism, based on droop control and model of VSG, can be divided as active power-frequency and reactive power-voltage control. Besides, the system stability is analyzed based on small signal model, for the design of inertia and damping. The simulation model is designed by MATLAB/Simulink for the implementation of VSG. In simulation, it is compared that the dynamic regulation performance of VSG with different control coefficient, such as virtual inertia, virtual damping, droop coefficient and integral coefficient. The optimization for regulation performance in simulation provides an appropriate selection method of the control coefficient for VSG. © 2021 Institute of Physics Publishing. All rights reserved.

关键词： Synchronous generators

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External blast load factors for dome structures based on reliability

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Defence Technology（防务技术） 2022年第2期18卷 170-182页

作者： Shao-bo Qi Guang-yan Huang Xu-dong Zhi Feng Fan Richard GJFlay State Key Laboratory of Explosion Science and Technology Beijing Institute of TechnologyBeijing100081PR China Key Lab of Structure Dynamic Behaviour and Control of the Ministry of Education Harbin Institute of TechnologyHarbin150090China Key Lab of Smart Prevention and Mitigation of Civil Engineering Disasters of Ministry of Industry and Information Technology Harbin Institute of TechnologyHarbin150090China Department of Mechanical Engineering University of AucklandPrivate Bag 92019Auckland1142New Zealand

Dome structures have been used extensively for industrial,residential,and military ***,it is necessary to understand the damage risk potential for such structures for blast-resistant design *** paper investigates the effect of blast load variability on the design value and the structural dynamic ***,the sources of uncertainty in the external blast load on dome structures were discussed *** based on the probabilistic blast load model for the dome,the rationality of a deterministic mass-increase safety method was *** was found that previous deterministic design method cannot provide a consistent and sound assurance factor or reliability index on the entire dome *** addition,it was also proved that the assurance-based load method fails to ensure compliance with structural safety design standards on the dome roof when compared with the reliability-based blast method.A sensitivity analysis on the probabilistic blast load was conducted,and the results indicate that stand-off distance and explosive mass both act as dominant sources to influence the mean and variability of blast ***,based on the Latin hypercube sampling method,a reliability-based external blast load factor technique was *** technique was further used to estimate structural damage levels of a single-layer reticulated dome under different reliability requirements,associated with a low,medium,and high level of protection grades for a specific explosion scenario,and it indicated that this technique can be useful in the building design to achieve a higher structural anti-explosion *** study herein can serve as a reference for the calculation method of designed blast load.

关键词： Dome structure Airblast variability Deterministic design Assurance factor Reliability-based blast load factor Structural damage levels

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Clustering of Photovoltaic Power Stations Based on the Improved AP Clustering Algorithm 49

Clustering of Photovoltaic Power Stations Based on the Impro...

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49th Annual Conference of the IEEE Industrial Electronics Society, IECON 2023

作者： Ding, Yawen Gao, Fei Jiang, Yingwei Hou, Kai Zhang, Donghui Shi, Xuewei College of Smart Energy Shanghai Jiao Tong University Key Laboratory of Control of Power Transmission and Conversion Ministry of Education Shanghai China Shanghai Jiao Tong University Key Laboratory of Control of Power Transmission and Conversion Ministry of Education Dept. of Electrical Engineering Shanghai China Nanjing China State Grid Jibei Zhangjiakou Wind and Solar Energy Storage and Transportation New Energy Co. Ltd Zhangjiakou China

ISBN: (纸本)9798350331820

To deal with the problem that uncertain parameter in Affinity Propagation (AP) clustering algorithm affects the clustering results, this paper proposes a clustering method based on AP clustering algorithm and Genetic Algorithm (GA) for Photovoltaic (PV) power stations. Firstly, the modeling of PV power stations is established and clustering index are determined according to the dynamic characteristics of PV power stations. Then the proposed method takes the silhouette index, which is used to evaluate the quality of the clustering result, as the fitness function of GA. The bias parameter placed on the main diagonal of the similarity matrix in the AP clustering algorithm is constantly iterated and updated until obtaining the optimization result. Finally, the studied case verifies the better clustering performance of the proposed method. The 20 PV power stations in the Taoling Substation can be simplified into three groups, reducing the complexity and calculation time for equivalent modeling. © 2023 IEEE.

关键词： Genetic algorithms

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Anthropogenic Oxygenated Volatile Organic Compounds Dominate Atmospheric Oxidation Capacity and Ozone Production via Secondary Formation of Formaldehyde in the Urban Atmosphere

ACS ES&T Air

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ACS ES&T Air 2025年第6期2卷 1033-1041页

作者： Hongtao Qian Bingye Xu Zhengning Xu Qiaoli Zou Qianxin Zi Hanfei Zuo Fei Zhang Jing Wei Xiangyu Pei WenXin Zhou Lingling Jin Xudong Tian Wenlong Zhao Zhibin Wang State Key Laboratory of Soil Pollution Control and Safety Zhejiang Provincial Key Laboratory of Organic Pollution Process and Control College of Environmental and Resource Sciences Zhejiang University Hangzhou 310058 China Ecological and Environmental Monitoring Center of Zhejiang Province Hangzhou 310012 China；Key Laboratory of Ecological and Environmental Monitoring Forewarning and Quality Control of Zhejiang Province Hangzhou 310012 China Ecological and Environmental Monitoring Center of Zhejiang Province Hangzhou 310012 China State Environmental Protection Key Laboratory of Formation and Prevention of Urban Air Pollution Complex Shanghai Academy of Environmental Sciences Shanghai 200233 China State Key Laboratory of Soil Pollution Control and Safety Zhejiang Provincial Key Laboratory of Organic Pollution Process and Control College of Environmental and Resource Sciences Zhejiang University Hangzhou 310058 China；ZJU-Hangzhou Global Scientific and Technological Innovation Center Zhejiang University Hangzhou 311200 China

Oxygenated volatile organic compounds (OVOCs) play an important role in the photochemical formation of ozone (O3). Comprehensive measurements and chemical box model analysis conducted in Hangzhou, China reveal that the formation of O3is strongly attributed to the increased atmospheric oxidation capacity (AOC). The observed OVOCs contribute 46.5 ± 8.3% to the AOC, especially during the pollution periods, with formaldehyde (HCHO) and acetaldehyde (CH3CHO) accounting for 19 ± 3.8% and 13.8 ± 4.1%, respectively. Various OVOCs (especially CH3CHO) act as key precursors for the initial production of the crucial radicals. These include the hydroperoxy radical (HO2), methyl peroxy radical (CH3O2), and acetyl peroxy radical (CH3CO3), accounting for 53.7 ± 5.0%, 13.9 ± 2.5%, and 10.0 ± 2.4% of the daytime O3production (P(O3)), respectively. HCHO acted as the key accelerator of HO2radical production and subsequently speeded up O3production. Model simulation and observational evidence reveal that the OVOC initiated secondary channel dominates the HCHO formation. The radical propagation chain of CH3CO3→ CH3O2→ CH3O→ HO2accounts for 62.4 ± 6.9% of HCHO production. CH3CHO chemistry can account for 14.0% of the production of O3, and degradation of secondary HCHO derived from CH3CHO accounts for 5.2% of total HO2production. These findings underscore the significant effect of OVOCs, particularly CH3CHO, on AOC and O3production in the urban atmosphere in eastern China. Given the decreasing trend of NOXconcentration, model simulations under different NOXlevels further imply that reducing anthropogenic emission sources of OVOCs is a crucial strategy for current O3control, and excessive reduction of NOXemissions (the daytime average concentration of NOXdecreases to below ∼ 2 ppb) may affect the effectiveness of reducing VOCs and promote a radical self-reaction.

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Non-explosive directional fracturing blasting using coal-based solid waste expanding agent

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Journal of Rock Mechanics and Geotechnical Engineering 2025年第6期17卷 3691-3710页

作者： Zhang, Quan He, Manchao Wang, Jiong Guo, Shan Wang, Chao Hong, Chenjie Chen, Kai Yang, Rongzhou Zhang, Xuepeng Yang, Jianwei School of Mines China University of Mining and Technology Xuzhou 221116 China State Key Laboratory of Explosion Science and Safety Protection Beijing Institute of Technology Beijing 100081 China State Key Laboratory of Geomechanics & Deep Underground Engineering China University of Mining and Technology Beijing 100083 China College of Environmental Science and Engineering Ocean University of China Qingdao 266100 China School of Civil Engineering and Architecture Anhui University of Science and Technology Huainan 232001 China State Key Laboratory of Strata Intelligent Control and Green Mining Co-founded by Shandong Province and the Ministry of Science and Technology Shandong University of Science and Technology Qingdao 266590 China China Coal Technology & Engineering Group Coal Mining Research Institute Beijing 100013 China

Aiming at mitigating the high risks associated with conventional explosive blasting, this study developed a safe directional fracturing technique, i.e. instantaneous expansion with a single fracture (IESF), using a coal-based solid waste expanding agent. First, the mechanism of directional fracturing blasting by the IESF was analyzed, and the criterion of directional crack initiation was established. On this basis, laboratory experiments and numerical simulations were conducted to systematically evaluate the directional fracturing blasting performance of the IESF. The results indicate that the IESF presents an excellent directional fracturing effect, with average surface undulation differences ranging from 8.1 mm to 22.7 mm on the fracture surfaces. Moreover, during concrete fracturing tests, the stresses and strains in the fracturing direction are measured to be 2.16–3.71 times and 8 times larger than those in the non-fracturing direction, respectively. Finally, the IESF technique was implemented for no-pillar mining with gob-side entry retaining through roof cutting and pressure relief in an underground coal mine. The IESF technique effectively created directional cracks in the roof without causing severe roadway deformation, achieving an average cutting rate and maximum roadway deformation of 94% and 197 mm, respectively. These on-site test results verified its excellent directional rock fracturing performance. The IESF technique, which is safe, efficient, and green, has considerable application prospects in the field of rock mechanics and engineering. © 2025 Institute of Rock and Soil Mechanics, Chinese Academy of Sciences

关键词： Coal-based solid waste expanding agent Crack initiation Directional fracturing blasting Non-explosive Stress-strain-damage evolution

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Reliability assessment of power systems with wind farms considering correlations 4

Reliability assessment of power systems with wind farms cons...

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4th International Conference on Advanced Electronic Materials, Computers and Software Engineering, AEMCSE 2021

作者： Wu, Yuwei Wu, Hai Hu, Guo Zhihua, Xu Qi, Huang NARI Technology Development Co. Ltd. Nanjing211106 China Nari Group Corporation State Key Laboratory of Smart Grid Protection and Control Jiangsu Nanjing211106 China

ISBN: (纸本)9781665415965

Wind power has the characteristics of randomness and intermittent, with the increasing unit capacity of wind turbines and wind farm scale, it is urgent to study the impact on generation and transmission system reliability. In addition, there are different degrees of correlation among regional multiple wind farms because of their geographic proximity. When it comes to research on the influence on the power system reliability, the analysis result will be larger error without considering the correlation, which is optimistic for reliability assessment. Therefore, it is meaningful to take the correlation into account in wind power system reliability assessment. In this paper, IEEE-RTS 79 generation and transmission reliability test system is adopted to verify the reliability assessment of power systems with wind farms considering correlations. The experimental results show that adding wind turbines in the original power system, system reliability has been greatly improved;and the system has higher reliability with given the considering the correlation between wind farms. © 2021 IEEE.

关键词： Wind farm

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