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Variance Analysis and Adaptive Sampling for Indirect Light Path Reuse

Journal of computer Science & Technology 2016年第3期31卷 547-560页

作者： Hao Qin Xin Sun Jun Yan Qi-Ming Hou Zhong Ren Kun Zhou State Key Laboratory of Computer Aided Design and Computer Graphics Zhejiang University Hangzhou 310058 China Microsoft Research Asia Beijing 100080 China

In this paper, we study the estimation variance of a set of global illumination algorithms based on indirect light path reuse. These algorithms usually contain two passes -- in the first pass, a small number of indirect light samples are generated and evaluated, and they are then reused by a large number of reconstruction samples in the second pass. Our analysis shows that the covariance of the reconstruction samples dominates the estimation variance under high reconstruction rates and increasing the reconstruction rate cannot effectively reduce the covariance. We also find that the covariance represents to what degree the indirect light samples are reused during reconstruction. This analysis motivates us to design a heuristic approximating the covariance as well as an adaptive sampling scheme based on this heuristic to reduce the rendering variance. We validate our analysis and adaptive sampling scheme in the indirect light field reconstruction algorithm and the axis-aligned filtering algorithm for indirect lighting. Experiments are in accordance with our analysis and show that rendering artifacts can be greatly reduced at a similar computational cost.

关键词： Monte Carlo method global illumination variance indirect light path reuse

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A Survey of Visual Analytic Pipelines

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Journal of computer Science & Technology 2016年第4期31卷 787-804页

作者： Xu-Meng Wang Tian-Ye Zhang Yu-Xin Ma Jing Xia Wei Chen State Key Laboratory of Computer Aided Design and Computer Graphics Zhejiang University Hangzhou 310058 China Innovation Joint Research Center for Cyber-Physical-Society System Zhejiang University Hangzhou 310058 China

Visual analytics has been widely studied in the past decade. One key to make visual analytics practical for both research and industrial applications is the appropriate definition and implementation of the visual analytics pipeline which provides effective abstractions for designing and implementing visual analytics systems. In this paper we review the previous work on visual analytics pipelines and individual modules from multiple perspectives： data, visualization, model and knowledge. In each module we discuss various representations and descriptions of pipelines inside the module, and compare the commonalities and the differences among them.

关键词： visual analytics pipeline visualization model knowledge

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Irradiance regression for efficient final gathering in global illumination

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Frontiers of computer Science 2015年第3期9卷 456-465页

作者： Xuezhen HUANG Xin SUN Zhong REN Xin TONG Baining GUO Kun ZHOU State Key Laboratory of Computer Aided Design and Computer Graphics Zhejiang University Hangzhou 310058 China Microsoft Research Asia Beijing 100029 China

Photon mapping is widely used for global illumi- nation rendering because of its high computational efficiency. But its efficiency is still limited, mainly by the intensive sam- piing required in final gathering, a process that is critical for removing low frequency artifacts of density estimation. In this paper, we propose a method to predict the final gather- ing estimation with direct density estimation, thereby achiev- ing high quality global illumination by photon mapping with high efficiency. We first sample the irradiance of a subset of shading points by both final gathering and direct radiance es- timation. Then we use the samples as a training set to predict the final gathered irradiance of other shading points through regression. Consequently, we are able to achieve about three times overall speedup compared with straightforward final gathering in global illumination computation with the same rendering quality.

关键词： global illumination photon mapping final gath-ering radiance estimation regression

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Weak-binding molecules are not drugs?-toward a systematic strategy for finding effective weak-binding drugs

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BRIEFINGS IN BIOINFORMATICS 2017年第2期18卷 321-332页

作者： Wang, Jinan Guo, Zihu Fu, Yingxue Wu, Ziyin Huang, Chao Zheng, Chunli Shar, Piar Ali Wang, Zhenzhong Xiao, Wei Wang, Yonghua Northwest A&F Univ Ctr Bioinformat Coll Life Sci Computer Aided Drug Design & TCM Syst Pharmacol Xianyang Shaanxi Peoples R China Northwest A&F Univ Ctr Bioinformat Coll Life SciModeling Signal Pathway Complex Dis TCM Syst Pharmacol & Machine Learning Xianyang Shaanxi Peoples R China Northwest A&F Univ Ctr Bioinformat Coll Life Sci Syst PharmacolNetwork Med & Computat Biol Xianyang Shaanxi Peoples R China Northwest A&F Univ Ctr Bioinformat Coll Life Sci TCM Syst PharmacolCell Regulat & Signal Transduc Xianyang Shaanxi Peoples R China Northwest A&F Univ Ctr Bioinformat Coll Life Sci Network BiolTCM Syst Pharmacol Xianyang Shaanxi Peoples R China Northwest A&F Univ Ctr Bioinformat Coll Life Sci Machine LearningTCM Syst Pharmacol Xianyang Shaanxi Peoples R China Kanion Pharmaceut Co Ltd Chinese Med Pharmaceut Proc State Key Lab New Tech R&D Director Lianyungang Peoples R China New Tech Chinese Med Qual Control New Extracting Tech Chinese Med Lianyungang Peoples R China Kanion Pharmaceut Co Ltd Chinese Med Pharmaceut Proc State Key Lab New Tech Lianyungang Peoples R China New Tech Chinese Med Qual control New Extracting Tech Chinese Med Lianyungang Peoples R China Northwest A&F Univ Ctr Bioinformat Coll Life Sci Xianyang Shaanxi Peoples R China ADME Properties Drug Mol TCM Syst Pharmacol Network Biol Xianyang Shaanxi Peoples R China Northwest A&F Univ Coll Life Sci Ctr Bioinformat Lab Syst Pharmacol Yangling 712100 Shaanxi Peoples R China

designing maximally selective ligands that act on individual drug targets with high binding affinity has been the central dogma of drug discovery and development for the past two decades. However, many low-affinity drugs that aim for several targets at the same time are found more effective than the high-affinity binders when faced with complex disease conditions, such as cancers, Alzheimer's disease and cardiovascular diseases. The aim of this study was to appreciate the importance and reveal the features of weak-binding drugs and propose an integrated strategy for discovering them. Weak-binding drugs can be characterized by their high dissociation rates and transient interactions with their targets. In addition, network topologies and dynamics parameters involved in the targets of weak-binding drugs also influence the effects of the drugs. Here, we first performed a dynamics analysis for 33 elementary subgraphs to determine the desirable topology and dynamics parameters among targets. Then, by applying the elementary subgraphs to the mitogen-activated protein kinase (MAPK) pathway, several optimal target combinations were obtained. Combining drug-target interaction prediction with molecular dynamics simulation, we got two potential weak-binding drug candidates, luteolin and tanshinone IIA, acting on these targets. Further, the binding affinity of these two compounds to their targets and the anti-inflammatory effects of them were validated through in vitro experiments. In conclusion, weak-binding drugs have real opportunities for maximum efficiency and may show reduced adverse reactions, which can offer a bright and promising future for new drug discovery.

关键词： weak-binding drug polypharmacology mathematical modeling systems pharmacology

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1-based construction of polycube maps from complex shapes

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ACM Transactions on graphics 2014年第3期33卷 1–11页

作者： Huang, Jin Jiang, Tengfei Shi, Zeyun Tong, Yiying Bao, Hujun Desbrun, Mathieu Key Lab of Computer-Aided Design and Computer Graphics Zhejiang University Hangzhou Zhejiang China Michigan State University East Lansing MI United States Caltech Pasadena CA United States

Polycube maps of triangle meshes have proved useful in a wide range of applications, including texture mapping and hexahedral mesh generation. However, constructing either fully automatically or with limited user control a low-distortion polycube from a detailed surface remains challenging in practice. We propose a variational method for deforming an input triangle mesh into a polycube shape through minimization of the 1-norm of the mesh normals, regularized via an as-rigid-as-possible volumetric distortion energy. Unlike previous work, our approach makes no assumption on the orientation, or on the presence of features in the input model. User-guided control over the resulting polycube map is also offered to increase design flexibility. We demonstrate the robustness, efficiency, and controllability of our method on a variety of examples, and explore applications in hexahedral remeshing and quadrangulation. © 2014 ACM.

关键词： Mesh generation

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Introduction

Advanced Topics in Science and Technology in China

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Advanced Topics in Science and Technology in China 2011年 1-6页

作者： Bao, Hujun Hua, Wei State key Lab of Computer Aided Design and Computer Graphics Zhejiang University Hangzhou310058 China

In this chapter, we are going to introduce the main parts of most rendering engines and, briefly, their functionality. Fig. 1.1 shows a classical structure of a rendering engine. In this graph, the rendering engine is composed of offline toolkits and a runtime support environment. The offline toolkit mainly comprises the tools that export data from the third party modeling software and the tools which perform some pre-operations to the Scene Model. These pre-operations include simplification, visibility pre-computation, lighting pre-computing and data compression. Besides these tools, the more advanced rendering engine includes some special effects generators. The main parts supported in Runtime are Scene Model, Scene Model Management, Scene Graph Traversal and Render. The applications call Scene Model Management and Scene Graph Traversal to run the rendering engine. In the following paragraphs, we will give a brief description of the core parts of the runtime support environment. © 2011, Zhejiang University Press, Hangzhou and Springer-Verlag Berlin Heidelberg.

关键词： Special effects

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44.2: An Analysis of Image Uniformity of Three-dimensional Image Based on Rotating LED Array Volumetric Display System

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SID Symposium Digest of Technical Papers 2012年第1期41卷

作者： Jiang Wu Caijie Yan Xinxing Xia Jia Hou Haifeng Li Xu Liu Wenting Zheng State Key Laboratory of Modern Optical Instrumentation Zhejiang University Hangzhou 310027 P.R. China State Key Laboratory of Computer Aided Design and Computer Graphics Zhejiang University Hangzhou 310058 P.R. China

We analyze the luminance uniformity and color uniformity of the color volumetric 3D display system based on a rotating LED screen. We first analyze the luminance and chromatic coordinate distribution for one RGB cube with different horizontal and vertical view angles and also luminance and color display effect for 64 spatial distributing RGB color cubes. To evaluate the luminance uniformity and color uniformity of 3D image with different display positions, we present three indexes for them respectively. for luminance uniformity, the indexes are the average luminance, the normalized luminance difference, and the average normalized luminance difference. And for color uniformity the indexes are the average of color difference, the maximum color difference, and the variance of color difference. By these evaluation parameters, we can compare luminance and color uniformity in different 3D volumetric display systems.

关键词：

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GPU-based dynamic quad stream for forest rendering

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Science China(Information Sciences) 2010年第8期53卷 1539-1545页

作者： LIU Feng, HUA Wei & BAO HuJun state key lab of computer aided design and computer graphics, Zhejiang University, Hangzhou 310058, China 1. State Key Lab of Computer Aided Design and Computer Graphics Zhejiang University Hangzhou 310058 China

Rendering large-scale forest scenes in real-time is a challenging problem, since the geometric complexity is far beyond the capabilities of current graphics hardware. In this paper, we propose a novel approach that adopts a dynamic quad stream residing on GPU buffers for view-dependent forest rendering. The incremental quad stream updating process is well-suited to the massively parallel architecture of the GPU pipeline, and it requires no continuous data exchange between CPU and GPU. The implementation of the algorithm is quite straightforward. Despite its simplicity, the algorithm achieves good performance with low memory, storage, and CPU costs.

关键词： real-time rendering large-scale forest quad stream geometry shader

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Preface

Advanced Topics in Science and Technology in China

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Advanced Topics in Science and Technology in China 2011年 v-vi页

作者： Bao, Hujun Hua, Wei State key Lab of Computer Aided Design and Computer Graphics Zhejiang University Hangzhou310058 China

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44.2: An analysis of image uniformity of three-dimensional image based on rotating LED array volumetric display system

44.2: An analysis of image uniformity of three-dimensional i...

引用

48th Annual SID Symposium, Seminar, and Exhibition 2010, Display Week 2010

作者： Wu, Jiang Yan, Caijie Xia, Xinxing Hou, Jia Li, Haifeng Liu, Xu Zheng, Wenting State Key Laboratory of Modern Optical Instrumentation Zhejiang University Hangzhou 310027 China State Key Laboratory of Computer Aided Design and Computer Graphics Zhejiang University Hangzhou 310058 China

ISBN: (纸本)9781618390950

We analyze the luminance uniformity and color uniformity of the color volumetric 3D display system based on a rotating LED screen. We first analyze the luminance and chromatic coordinate distribution for one RGB cube with different horizontal and vertical view angles and also luminance and color display effect for 64 spatial distributing RGB color cubes. To evaluate the luminance uniformity and color uniformity of 3D image with different display positions, we present three indexes for them respectively. For luminance uniformity, the indexes are the average luminance, the normalized luminance difference, and the average normalized luminance difference. And for color uniformity the indexes are the average of color difference, the maximum color difference, and the variance of color difference. By these evaluation parameters, we can compare luminance and color uniformity in different 3D volumetric display systems.

关键词： Luminance

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