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Controlling of apoptosis and proliferation of HepG2 cancer cells by treatment of plasma jet and N-acetylcysteine combination

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Clinical Plasma Medicine 2018年 9卷 12-13页

作者： Xiong, Zilan Zhao, Shasha State Key Laboratory of Advanced Electromagnetic Engineering and Technology School of Electrical and Electronic Engineering Huazhong University of Science and Technology (HUST) Wuhan China 430074 School of Life Science and Health Wuhan University of Science and Technology Wuhan China 430065

It is well known that atmospheric pressure plasma could induce apoptosis of cancer cells. [1][2] However, the interaction and mechanism between plasma and cancer cells has not been fully understood yet. [3] Here, we report the controlment of apoptosis and proliferation of human hepatocellular carcinoma cell (HepG2) by combined treatment of He/O2 plasma jet and N-acetylcysteine (NAC, free radical scavenger). It is found that the fate of HepG2 cells could be controlled by plasma treatment time together with NAC pretreatment. Pure plasma treatment could induce apoptosis of HepG2 cells. However, on one hand, 15s plasma with NAC pre-treatment could enhance proliferation of HepG2 cell as a function of NAC concentration. On the other hand, NAC-pretreatment could markedly compromise apoptosis effect by long time plasma treatment (e.g. >240s) without proliferation observed. The NAC and 15s plasma treatment accelerates the G1 to S phase transition of HepG2 cells causing proliferation while long time plasma treatment arrests the cell cycle at the G2/M phase inducing apoptosis.

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Main control system of the linear accelerator for the HUST THz-FEL 8

Main control system of the linear accelerator for the HUST T...

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8th International Particle Accelerator Conference, IPAC 2017

作者： Tang, B. Hu, T.N. Xiong, Y.N. Chen, Q.S. Jiang, J. State Key Laboratory of Advanced Electromagnetic Engineering and Technology College of Electrical and Electronic Engineering HUST Wuhan430074 China

ISBN: (纸本)9783954501823

A free-electron laser terahertz source (THz-FEL) with a table-top scale is constructed in Huazhong University of Science & technology. The whole facility is under joint-debugging currently, and main measured parameters have already matched with design targets. This paper describes the main control system of the Linac-based injector, especially auto-matching and auto-commissioning modules. The former occurs at the beginning of daily operation, which contains one key pre-heating and searching the best electric parameters and RF parameters automatically based on last operation status. The later applies in beam commissioning for both Linac and transport line combining with beam diagnostic system, which could save operation time and improve commissioning efficiency. Moreover, real-time monitoring and controlling for water-cooling and vacuum states are inserted in the main control system to protect the accelerator. © 2017 CC-BY-3.0 and by the respective authors

关键词： Free electron lasers

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Super-Twisting algorithm based sliding mode observer for wide-speed range PMSM sensorless control considering VSI nonlinearity

Super-Twisting algorithm based sliding mode observer for wid...

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2017 IEEE International Electric Machines and Drives Conference, IEMDC 2017

作者： Liang, Donglai Li, Jian Qu, Ronghai State Key Laboratory of Advanced Electromagnetic Engineering and Technology School of Electrical and Electronic Engineering Huazhong University of Science and Technology Wuhan China

ISBN: (纸本)9781509042814

This paper proposed a super-Twisting algorithm based sliding mode observer (STA-SMO) for permanent magnet synchronous machine (PMSM) sensorless control, in which voltage-source inverter (VSI) nonlinearity is taken into consideration. A lookup table for online tunning sliding mode coefficients of STA-SMO is obtained based on existing stable conditions. Since mismatch between reference and actual voltage due to VSI nonlinearity may lead not only to estimation error but also to system instability, especially at low speed range. Voltage distortion due to VSI nonlinearity is compensated to improve the estimation accuracy. A high-frequency harmonic components extraction method is used to compensate the VSI nonlinearity. Thus, a STA-SMO with suitable sliding mode coefficients and accurate voltage parameters is obtained. The effectiveness of the proposed sensorless control method with VSI nonlinearity compensation is verified on a surface-mounted PMSM by simulations and experiments. © 2017 IEEE.

关键词： Sensorless control

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Sensorless Control of Stand-Alone BDFIG with Compensation from Rotor Speed Observer 2

Sensorless Control of Stand-Alone BDFIG with Compensation fr...

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2nd International Conference on Electrical and Electronic engineering, ICEEE 2017

作者： Dong, Dinghao Xu, Wei Liu, Yi Ye, Caiyong Rabiul Islam, Md. State Key Laboratory of Advanced Electromagnetic Engineering and Technology Huazhong University of Science and Technology Wuhan China Rajshahi University of Engineering Technology Rajshahi Bangladesh

ISBN: (纸本)9781538633403

Brushless double-fed induction generator (BDFIG) is the upgrade of conventional double-fed induction generator (DFIG) for needless of the brush and slip ring. It can be used for ship shaft power generator system, in which the BDFIG mainly works at stand-Alone state. The encoderless operation can enhance the system's reliability and reduce the cost. This paper proposes a modified sensorless control method of BDFIG which can realize precise phase angle control. That can be important when it is used for connecting the machine to the grid quickly and reliably. A rotor speed observer (RSO) is used to supply the feed-forward compensation. Experimental results are given to prove the effectiveness of proposed method. © 2017 IEEE.

关键词： Sensorless control

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Outside Front Cover Picture: Plasma Process. Polym. 10/2020

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Plasma Processes and Polymers 2020年第10期17卷

作者： Jiangwei Duan Mingyu Ma Maksudbek Yusupov Rodrigo M. Cordeiro Xinpei Lu Annemie Bogaerts State Key Laboratory of Advanced Electromagnetic Engineering and Technology School of Electrical and Electronic Engineering Huazhong University of Science and Technology Wuhan China IFSA Collaborative Innovation Center Shanghai Jiao Tong University Shanghai China Research Group PLASMANT Department of Chemistry University of Antwerp Antwerp Belgium Centro de Ciências Naturais e Humanas Universidade Federal do ABC Santo André Santo André São Paulo Brazil Annemie Bogaerts Research Group PLASMANT Department of Chemistry University of Antwerp Antwerp-Wilrijk Belgium. Xinpei Lu State Key Laboratory of Advanced Electromagnetic Engineering and Technology School of Electrical and Electronic Engineering Huazhong University of Science and Technology 430074 Wuhan China.

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Simulation of Sensorless Control for the Start-up of Large-Scale Synchronous Condenser Using Static Frequency Converter

Simulation of Sensorless Control for the Start-up of Large-S...

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2018 International Conference on advanced Technologies in Energy, Environmental and Electrical engineering (AT3E 2018)

作者： Li Li Hao Zuo Siyuan Guo Jin Wang Jiawei Zhao State Grid Hunan Electric Power Company Limited Research Institute State Key Laboratory of Advanced Electromagnetic Engineering and Technology School of Electrical and Electronic Engineering Huazhong University of Science and Technology

In this paper, the structural characteristics of large synchronous condensers and the working principle of static frequency converter are studied firstly. Intermittent commutation and natural commutation are adopted by the inverter on the machine side in low-speed and high-speed stage respectively. Second, methods of sensorless control in different conditions are proposed. The initial rotor position is estimated through two methods, the terminal voltage method and the rotor-flux-oriented method. And similar methods are used in low-speed stage. Besides, phase-locked loop is used in high-speed. Finally, simulation models are established in PSCAD/EMDTC. The rotor-flux-oriented method used in standstill condition and low-speed stage shows better accuracy. And the phase-locked loop is also effective in high-speed stage. Therefore, the sensorless control methods are feasible.

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Positive and negative sequence control of DFIG based wind turbines and its impact on grid voltage profile concerning converter control capability

Positive and negative sequence control of DFIG based wind tu...

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6th International Conference on Renewable Power Generation

作者： Yan, Lun Yuan, Xiaoming State Key Laboratory of Advanced Electromagnetic Engineering and Technology Huazhong University of Science and Technology Huazhong China

As grid-connected doubly fed induction generator (DFIG) based wind turbines have become a significant power source, in order to meet grid code and ensure its safe operation during asymmetrical grid faults, many improved control algorithms have been developed for the rotor-side converter (RSC). However, most of them did not take the RSC control capability constraint into account and may cause overcurrent problem in the rotor side under serve asymmetric faults. In this study, first a new positive and negative sequence current control scheme for the RSC is designed so that DFIG can operate well during serve asymmetrical faults. Then, due to the RSC capability constraint, the controllable regions of DFIG are analysed while the limitation of DFIG is given. Based on the controllable regions and limitation of DFIG, the limitation and division strategies between DFIG rotor positive and negative sequence current are also developed theoretically. Finally, a typical system of a 45 MW DFIG-based wind farm connected to power system is used to verify the effectiveness of the developed rotor positive and negative sequence current limitation and division strategies and study their impact on grid voltage profile during various asymmetrical faults in Matlab/ Simulink software. © 2017 Institution of engineering and technology. All rights reserved.

关键词： Wind turbines

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Comparison of surface PM vernier motors with interior PM motors for traction application

Comparison of surface PM vernier motors with interior PM mot...

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2017 IEEE Transportation Electrification Conference and Expo, Asia-Pacific, ITEC Asia-Pacific 2017

作者： Qu, Ronghai Li, Dawei Gao, Yuting Zou, Tianjie State Key Laboratory of Advanced Electromagnetic Engineering and Technology School of Electrical and Electronic Engineering Huazhong University of Science and Technology Wuhan430074 China

ISBN: (纸本)9781538628942

Surface permanent magnet vernier (SPMV) motors are gaining more and more attentions over recent years due to their high torque density. Generally, most researches focuses on their applications in low speed, high torque area, and the study on their high speed operation is rarely seen. In this paper, a SPMV motor with 12 slot, 20 rotor pole is evaluated for traction application. The optimal designed SPMV motor is compared with the Prius-2004 interior permanent magnet (IPM) motor in terms of back-EMF, cogging torque, torque, field weakening ability, losses, efficiency and fault tolerance. The analyzing results show that the SPMV machine produces 12% higher torque under the same DC copper loss. However, the core loss and magnet loss of the SPMV motor are 2.5 and 6.25 times that of the IPM motor. Besides, the SPMV motor has inherently optimal flux-weakening capability despite its surface-mounted PM structure. Moreover, the anti- demagnetization capability of the SPMV motor with pole shoes to protect the magnets, is similar to that of the Prius PM motor. © 2017 IEEE.

关键词： Permanent magnets

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Control and design of a four-switch inverter with reduced low-frequency input current ripple and capacitance requirement: A comparative study 32

Control and design of a four-switch inverter with reduced lo...

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32nd Annual IEEE Applied Power Electronics Conference and Exposition, APEC 2017

作者： Shi, Youjie Liu, Bangyin Duan, Shanxu State Key Laboratory of Advanced Electromagnetic Engineering and Technology School of Electrical and Electronic Engineering Huazhong University of Science and Technology Wuhan430074 China

ISBN: (纸本)9781509053667

A large amount of ripple at twice the output frequency will emerge in the input current at dc side due to the pulsating output power in a single-phase dc-ac power conversion system. In this paper, a current-source-type four-switch inverter based on switch multiplexing technique is studied, which can realize the reduction of input low-frequency current ripple as well as dc capacitor requirement. To get a more complete understanding of its performance, a full comparison is presented between it and the traditional two-stage single-phase inverter in the aspects of operation principle, equivalent circuit model, power decoupling method, key circuit parameter, and system efficiency. The four-switch inverter is proved to be input-ripple-free and more efficient, and its size is much smaller because the dc capacitor can be reduced significantly. Finally, experimental results performed on two single-phase inverter prototypes verify the analysis and conclusions. © 2017 IEEE.

关键词： Electric inverters

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Preliminary design of beam diagnostic system in the HUST-PTF beamline 6

Preliminary design of beam diagnostic system in the HUST-PTF...

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6th International Beam Instrumentation Conference, IBIC 2017

作者： Liu, X. Chen, Q.S. Qin, B. Tang, K. Chen, W. State Key Laboratory of Advanced Electromagnetic Engineering and Technology School of Electrical and Electronic Engineering Huazhong University of Science and Technology Wuhan430074 China

ISBN: (纸本)9783954501922

Proton therapy is now recognized as one of the most effective radiation therapy methods for cancers. A proton therapy facility with multiple gantry treatment rooms is under development in HUST (Huazhong University of Science and technology), which is based on isochronous superconducting cyclotron scheme. The 250MeV/500nA proton beam will be extracted from a superconducting cyclotron and injected into the beam-line. Many beam diagnostic instruments are distributed throughout the beam line to measure the beam profile, position, current, loss, energy and energy spread. Some of them will send the beam information to the treatment control system (TCS) and serve as the safety interlock. This paper presents the considerations for the distribution of beam diagnostic instruments and shows the layout of beam diagnostics monitors in the beamline. © 2018 by JACoW - cc Creative Commons Attribution 3.0.

关键词： Cyclotrons

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