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Search for pairs of muons with small displacements in pp collisions at s=13 TeV with the ATLAS detector

Physics Letters, Section B: Nuclear, Elementary Particle and High-Energy Physics 2023年 846卷

作者： Aad, G. Abbott, B. Abeling, K. Abicht, N.J. Abidi, S.H. Aboulhorma, A. Abramowicz, H. Abreu, H. Abulaiti, Y. Abusleme Hoffman, A.C. Acharya, B.S. Adam Bourdarios, C. Adamczyk, L. Adamek, L. Addepalli, S.V. Addison, M.J. Adelman, J. Adiguzel, A. Adye, T. Affolder, A.A. Afik, Y. Agaras, M.N. Agarwala, J. Aggarwal, A. Agheorghiesei, C. Ahmad, A. Ahmadov, F. Ahmed, W.S. Ahuja, S. Ai, X. Aielli, G. Ait Tamlihat, M. Aitbenchikh, B. Aizenberg, I. Akbiyik, M. Åkesson, T.P.A. Akimov, A.V. Akiyama, D. Akolkar, N.N. Al Khoury, K. Alberghi, G.L. Albert, J. Albicocco, P. Albouy, G.L. Alderweireldt, S. Aleksa, M. Aleksandrov, I.N. Alexa, C. Alexopoulos, T. Alfonsi, A. Alfonsi, F. Algren, M. Alhroob, M. Ali, B. Ali, H.M.J. Ali, S. Alibocus, S.W. Aliev, M. Alimonti, G. Alkakhi, W. Allaire, C. Allbrooke, B.M.M. Allen, J.F. Allendes Flores, C.A. Allport, P.P. Aloisio, A. Alonso, F. Alpigiani, C. Alvarez Estevez, M. Alvarez Fernandez, A. Alviggi, M.G. Aly, M. Amaral Coutinho, Y. Ambler, A. Amelung, C. Amerl, M. Ames, C.G. Amidei, D. Amor Dos Santos, S.P. Amos, K.R. Ananiev, V. Anastopoulos, C. Andeen, T. Anders, J.K. Andrean, S.Y. Andreazza, A. Angelidakis, S. Angerami, A. Anisenkov, A.V. Annovi, A. Antel, C. Anthony, M.T. Antipov, E. Antonelli, M. Antrim, D.J.A. Anulli, F. Aoki, M. Aoki, T. Aparisi Pozo, J.A. Aparo, M.A. Aperio Bella, L. Appelt, C. Apyan, A. Aranzabal, N. Arcangeletti, C. Arce, A.T.H. Arena, E. Arguin, J.-F. Argyropoulos, S. Arling, J.-H. Armbruster, A.J. Arnaez, O. Arnold, H. Arrubarrena Tame, Z.P. Artoni, G. Asada, H. Asai, K. Asai, S. Asbah, N.A. Assahsah, J. Assamagan, K. Astalos, R. Atashi, S. Atkin, R.J. Atkinson, M. Atlay, N.B. Atmani, H. Atmasiddha, P.A. Augsten, K. Auricchio, S. Auriol, A.D. Austrup, V.A. Avolio, G. Axiotis, K. Azuelos, G. Babal, D. Bachacou, H. Bachas, K. Bachiu, A. Backman, F. Badea, A. Bagnaia, P. Bahmani, M. Bailey, A.J. Bailey, V.R. Baines, J.T. Baines, L. Bakalis, C. Baker, O.K. Bakos, E. Bakshi Gupta, D. Balasubramanian, R. Baldin, E.M. Balek, P. Ballabene, E. Balli, F. Baltes, L.M Department of Physics University of Adelaide Adelaide Australia Department of Physics University of Alberta Edmonton AB Canada Department of Physics Ankara University Ankara Turkey Division of Physics TOBB University of Economics and Technology Ankara Turkey LAPP Université Savoie Mont Blanc CNRS/IN2P3 Annecy France APC Université Paris Cité CNRS/IN2P3 Paris France High Energy Physics Division Argonne National Laboratory Argonne IL United States Department of Physics University of Arizona Tucson AZ United States Department of Physics University of Texas at Arlington Arlington TX United States Physics Department National and Kapodistrian University of Athens Athens Greece Physics Department National Technical University of Athens Zografou Greece Department of Physics University of Texas at Austin Austin TX United States Institute of Physics Azerbaijan Academy of Sciences Baku Azerbaijan Institut de Física d'Altes Energies (IFAE) Barcelona Institute of Science and Technology Barcelona Spain Institute of High Energy Physics Chinese Academy of Sciences Beijing China Physics Department Tsinghua University Beijing China Department of Physics Nanjing University Nanjing China School of Science Shenzhen Campus of Sun Yat-sen University China University of Chinese Academy of Science (UCAS) Beijing China Institute of Physics University of Belgrade Belgrade Serbia Department for Physics and Technology University of Bergen Bergen Norway Physics Division Lawrence Berkeley National Laboratory Berkeley CA United States Institut für Physik Humboldt Universität zu Berlin Berlin Germany Albert Einstein Center for Fundamental Physics Laboratory for High Energy Physics University of Bern Bern Switzerland School of Physics and Astronomy University of Birmingham Birmingham United Kingdom Department of Physics Bogazici University Istanbul Turkey Department of Physics Engineering Gaziantep University Gaziantep Turkey Department of Physics Istanbul Un

A search for new phenomena giving rise to pairs of opposite electrically charged muons with impact parameters in the millimeter range is presented, using 139 fb−1 of s=13 TeV pp collision data from the ATLAS detector ...

A search for new phenomena giving rise to pairs of opposite electrically charged muons with impact parameters in the millimeter range is presented, using 139 fb⁻¹ of s=13 TeV pp collision data from the ATLAS detector at the LHC. The search targets the gap in coverage between existing searches targeting final states with leptons with large displacement and prompt leptons. No significant excess over the background expectation is observed and exclusion limits are set on the mass of long-lived scalar supersymmetric muon-partners (smuons) with much lower lifetimes than previously targeted by displaced muon searches. Smuon lifetimes down to 1 ps are excluded for a smuon mass of 100 GeV, and smuon masses up to 520 GeV are excluded for a proper lifetime of 10 ps, at 95% confidence level. Finally, model-independent limits are set on the contribution from new phenomena to the signal-region yields. © 2023 The Author(s)

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Combination of searches for invisible decays of the Higgs boson using 139 fb⁻¹ of proton-proton collision data at s=13 TeV collected with the ATLAS experiment

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Physics Letters, Section B: Nuclear, Elementary Particle and High-Energy Physics 2023年 842卷

作者： Aad, G. Abbott, B. Abeling, K. Abidi, S.H. Aboulhorma, A. Abramowicz, H. Abreu, H. Abulaiti, Y. Abusleme Hoffman, A.C. Acharya, B.S. Adam Bourdarios, C. Adamczyk, L. Adamek, L. Addepalli, S.V. Adelman, J. Adiguzel, A. Adorni, S. Adye, T. Affolder, A.A. Afik, Y. Agaras, M.N. Agarwala, J. Aggarwal, A. Agheorghiesei, C. Aguilar-Saavedra, J.A. Ahmad, A. Ahmadov, F. Ahmed, W.S. Ahuja, S. Ai, X. Aielli, G. Ait Tamlihat, M. Aitbenchikh, B. Aizenberg, I. Akbiyik, M. Åkesson, T.P.A. Akimov, A.V. Akolkar, N.N. Al Khoury, K. Alberghi, G.L. Albert, J. Albicocco, P. Alderweireldt, S. Aleksa, M. Aleksandrov, I.N. Alexa, C. Alexopoulos, T. Alfonsi, A. Alfonsi, F. Alhroob, M. Ali, B. Ali, S. Aliev, M. Alimonti, G. Alkakhi, W. Allaire, C. Allbrooke, B.M.M. Allendes Flores, C.A. Allport, P.P. Aloisio, A. Alonso, F. Alpigiani, C. Alvarez Estevez, M. Alvarez Fernandez, A. Alviggi, M.G. Aly, M. Amaral Coutinho, Y. Ambler, A. Amelung, C. Amerl, M. Ames, C.G. Amidei, D. Amor Dos Santos, S.P. Amos, K.R. Ananiev, V. Anastopoulos, C. Andeen, T. Anders, J.K. Andrean, S.Y. Andreazza, A. Angelidakis, S. Angerami, A. Anisenkov, A.V. Annovi, A. Antel, C. Anthony, M.T. Antipov, E. Antonelli, M. Antrim, D.J.A. Anulli, F. Aoki, M. Aoki, T. Aparisi Pozo, J.A. Aparo, M.A. Aperio Bella, L. Appelt, C. Aranzabal, N. Araujo Ferraz, V. Arcangeletti, C. Arce, A.T.H. Arena, E. Arguin, J.-F. Argyropoulos, S. Arling, J.-H. Armbruster, A.J. Arnaez, O. Arnold, H. Arrubarrena Tame, Z.P. Artoni, G. Asada, H. Asai, K. Asai, S. Asbah, N.A. Assahsah, J. Assamagan, K. Astalos, R. Atkin, R.J. Atkinson, M. Atlay, N.B. Atmani, H. Atmasiddha, P.A. Augsten, K. Auricchio, S. Auriol, A.D. Austrup, V.A. Avner, G. Avolio, G. Axiotis, K. Azuelos, G. Babal, D. Bachacou, H. Bachas, K. Bachiu, A. Backman, F. Badea, A. Bagnaia, P. Bahmani, M. Bailey, A.J. Bailey, V.R. Baines, J.T. Bakalis, C. Baker, O.K. Bakos, E. Bakshi Gupta, D. Balasubramanian, R. Baldin, E.M. Balek, P. Ballabene, E. Balli, F. Baltes, L.M. Balunas, W.K. Balz, J. Banas, E. Bandieramonte, M. Bandyopadhyay, A. B Department of Physics University of Adelaide Adelaide Australia Department of Physics University of Alberta Edmonton AB Canada Department of Physics Ankara University Ankara Turkey Division of Physics TOBB University of Economics and Technology Ankara Turkey LAPP Univ. Savoie Mont Blanc CNRS/IN2P3 Annecy France APC Université Paris Cité CNRS/IN2P3 Paris France High Energy Physics Division Argonne National Laboratory Argonne IL United States Department of Physics University of Arizona Tucson AZ United States Department of Physics University of Texas at Arlington Arlington TX United States Physics Department National and Kapodistrian University of Athens Athens Greece Physics Department National Technical University of Athens Zografou Greece Department of Physics University of Texas at Austin Austin TX United States Institute of Physics Azerbaijan Academy of Sciences Baku Azerbaijan Institut de Física d'Altes Energies (IFAE) Barcelona Institute of Science and Technology Barcelona Spain Institute of High Energy Physics Chinese Academy of Sciences Beijing China Physics Department Tsinghua University Beijing China Department of Physics Nanjing University Nanjing China University of Chinese Academy of Science (UCAS) Beijing China Institute of Physics University of Belgrade Belgrade Serbia Department for Physics and Technology University of Bergen Bergen Norway Physics Division Lawrence Berkeley National Laboratory Berkeley CA United States Institut für Physik Humboldt Universität zu Berlin Berlin Germany Albert Einstein Center for Fundamental Physics Laboratory for High Energy Physics University of Bern Bern Switzerland School of Physics and Astronomy University of Birmingham Birmingham United Kingdom Department of Physics Bogazici University Istanbul Turkey Department of Physics Engineering Gaziantep University Gaziantep Turkey Department of Physics Istanbul University Istanbul Turkey Istinye University Sariyer Istanbul Turkey

Many extensions of the Standard Model predict the production of dark matter particles at the LHC. Sufficiently light dark matter particles may be produced in decays of the Higgs boson that would appear invisible to the detector. This Letter presents a statistical combination of searches for H→invisible decays where multiple production modes of the Standard Model Higgs boson are considered. These searches are performed with the ATLAS detector using 139 fb⁻¹ of proton–proton collisions at a centre–of–mass energy of [Formula presented] at the LHC. In combination with the results at [Formula presented] and [Formula presented], an upper limit on the H→invisible branching ratio of 0.107 (0.077) at the 95% confidence level is observed (expected). These results are also interpreted in the context of models where the 125 GeV Higgs boson acts as a portal to dark matter, and limits are set on the scattering cross-section of weakly interacting massive particles and nucleons. © 2023 The Author(s)

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Measurement of the cross-sections of the electroweak and total production of a Zγ pair in association with two jets in pp collisions at s=13 TeV with the ATLAS detector

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Physics Letters, Section B: Nuclear, Elementary Particle and High-Energy Physics 2023年 846卷

作者： Aad, G. Abbott, B. Abeling, K. Abicht, N.J. Abidi, S.H. Aboulhorma, A. Abramowicz, H. Abreu, H. Abulaiti, Y. Abusleme Hoffman, A.C. Acharya, B.S. Adam Bourdarios, C. Adamczyk, L. Adamek, L. Addepalli, S.V. Addison, M.J. Adelman, J. Adiguzel, A. Adye, T. Affolder, A.A. Afik, Y. Agaras, M.N. Agarwala, J. Aggarwal, A. Agheorghiesei, C. Ahmad, A. Ahmadov, F. Ahmed, W.S. Ahuja, S. Ai, X. Aielli, G. Aikot, A. Ait Tamlihat, M. Aitbenchikh, B. Aizenberg, I. Akbiyik, M. Åkesson, T.P.A. Akimov, A.V. Akiyama, D. Akolkar, N.N. Al Khoury, K. Alberghi, G.L. Albert, J. Albicocco, P. Albouy, G.L. Alderweireldt, S. Aleksa, M. Aleksandrov, I.N. Alexa, C. Alexopoulos, T. Alfonsi, F. Algren, M. Alhroob, M. Ali, B. Ali, H.M.J. Ali, S. Alibocus, S.W. Aliev, M. Alimonti, G. Alkakhi, W. Allaire, C. Allbrooke, B.M.M. Allen, J.F. Allendes Flores, C.A. Allport, P.P. Aloisio, A. Alonso, F. Alpigiani, C. Alvarez Estevez, M. Alvarez Fernandez, A. Alves Cardoso, M. Alviggi, M.G. Aly, M. Amaral Coutinho, Y. Ambler, A. Amelung, C. Amerl, M. Ames, C.G. Amidei, D. Amor Dos Santos, S.P. Amos, K.R. Ananiev, V. Anastopoulos, C. Andeen, T. Anders, J.K. Andrean, S.Y. Andreazza, A. Angelidakis, S. Angerami, A. Anisenkov, A.V. Annovi, A. Antel, C. Anthony, M.T. Antipov, E. Antonelli, M. Anulli, F. Aoki, M. Aoki, T. Aparisi Pozo, J.A. Aparo, M.A. Aperio Bella, L. Appelt, C. Apyan, A. Aranzabal, N. Arcangeletti, C. Arce, A.T.H. Arena, E. Arguin, J.-F. Argyropoulos, S. Arling, J.-H. Arnaez, O. Arnold, H. Artoni, G. Asada, H. Asai, K. Asai, S. Asbah, N.A. Assahsah, J. Assamagan, K. Astalos, R. Atashi, S. Atkin, R.J. Atkinson, M. Atmani, H. Atmasiddha, P.A. Augsten, K. Auricchio, S. Auriol, A.D. Austrup, V.A. Avolio, G. Axiotis, K. Azuelos, G. Babal, D. Bachacou, H. Bachas, K. Bachiu, A. Backman, F. Badea, A. Bagnaia, P. Bahmani, M. Bailey, A.J. Bailey, V.R. Baines, J.T. Baines, L. Bakalis, C. Baker, O.K. Bakos, E. Bakshi Gupta, D. Balakrishnan, V. Balasubramanian, R. Baldin, E.M. Balek, P. Ballabene, E. Balli, F. Baltes, L.M. Balunas, W.K. Balz, J. Banas, E. Department of Physics University of Adelaide Adelaide Australia Department of Physics University of Alberta Edmonton AB Canada Department of Physics Ankara University Ankara Turkey Division of Physics TOBB University of Economics and Technology Ankara Turkey LAPP Université Savoie Mont Blanc CNRS/IN2P3 Annecy France APC Université Paris Cité CNRS/IN2P3 Paris France High Energy Physics Division Argonne National Laboratory IL Argonne United States Department of Physics University of Arizona Tucson AZ United States Department of Physics University of Texas at Arlington Arlington TX United States Physics Department National and Kapodistrian University of Athens Athens Greece Physics Department National Technical University of Athens Zografou Greece Department of Physics University of Texas at Austin Austin TX United States Institute of Physics Azerbaijan Academy of Sciences Baku Azerbaijan Institut de Física d'Altes Energies (IFAE) Barcelona Institute of Science and Technology Barcelona Spain Institute of High Energy Physics Chinese Academy of Sciences Beijing China Physics Department Tsinghua University Beijing China Department of Physics Nanjing University Nanjing China School of Science Campus of Sun Yat-sen University Shenzhen China University of Chinese Academy of Science (UCAS) Beijing China Institute of Physics University of Belgrade Belgrade Serbia Department for Physics and Technology University of Bergen Bergen Norway Physics Division Lawrence Berkeley National Laboratory Berkeley CA United States University of California Berkeley CA United States Institut für Physik Humboldt Universität zu Berlin Berlin Germany Albert Einstein Center for Fundamental Physics Laboratory for High Energy Physics University of Bern Bern Switzerland School of Physics and Astronomy University of Birmingham Birmingham United Kingdom Department of Physics Bogazici University Istanbul Turkey Department of Physics Engineering Gaziantep Universit

This Letter presents the measurement of the fiducial and differential cross-sections of the electroweak production of a Zγ pair in association with two jets. The analysis uses 140 fb⁻¹ of LHC proton–proton collision data taken at s=13 TeV recorded by the ATLAS detector during the years 2015–2018. Events with a Z boson candidate decaying into either an e⁺e⁻ or μ⁺μ⁻ pair, a photon and two jets are selected. The electroweak component is extracted by requiring a large dijet invariant mass and by using the information about the centrality of the system and is measured with an observed and expected significance well above five standard deviations. The fiducial pp→Zγjj cross-section for the electroweak production is measured to be 3.6 ± 0.5 fb. The total fiducial cross-section that also includes contributions where the jets arise from strong interactions is measured to be 16.8_−1.8^+2.0 fb. The results are consistent with the Standard Model predictions. Differential cross-sections are also measured using the same events and are compared with parton-shower Monte Carlo simulations. Good agreement is observed between data and predictions. © 2023 The Author(s)

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Search for nonresonant pair production of Higgs bosons in the bb¯bb¯ final state in pp collisions at s=13 TeV with the ATLAS detector

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Physical Review D 2023年第5期108卷 052003-052003页

作者： G. Aad B. Abbott K. Abeling S. H. Abidi A. Aboulhorma H. Abramowicz H. Abreu Y. Abulaiti A. C. Abusleme Hoffman B. S. Acharya C. Adam Bourdarios L. Adamczyk L. Adamek S. V. Addepalli J. Adelman A. Adiguzel S. Adorni T. Adye A. A. Affolder Y. Afik M. N. Agaras J. Agarwala A. Aggarwal C. Agheorghiesei J. A. Aguilar-Saavedra A. Ahmad F. Ahmadov W. S. Ahmed S. Ahuja X. Ai G. Aielli M. Ait Tamlihat B. Aitbenchikh I. Aizenberg M. Akbiyik T. P. A. Åkesson A. V. Akimov K. Al Khoury G. L. Alberghi J. Albert P. Albicocco S. Alderweireldt M. Aleksa I. N. Aleksandrov C. Alexa T. Alexopoulos A. Alfonsi F. Alfonsi M. Alhroob B. Ali S. Ali M. Aliev G. Alimonti W. Alkakhi C. Allaire B. M. M. Allbrooke C. A. Allendes Flores P. P. Allport A. Aloisio F. Alonso C. Alpigiani M. Alvarez Estevez A. Alvarez Fernandez M. G. Alviggi M. Aly Y. Amaral Coutinho A. Ambler C. Amelung M. Amerl C. G. Ames D. Amidei S. P. Amor Dos Santos K. R. Amos V. Ananiev C. Anastopoulos T. Andeen J. K. Anders S. Y. Andrean A. Andreazza S. Angelidakis A. Angerami A. V. Anisenkov A. Annovi C. Antel M. T. Anthony E. Antipov M. Antonelli D. J. A. Antrim F. Anulli M. Aoki T. Aoki J. A. Aparisi Pozo M. A. Aparo L. Aperio Bella C. Appelt N. Aranzabal V. Araujo Ferraz C. Arcangeletti A. T. H. Arce E. Arena J-F. Arguin S. Argyropoulos J.-H. Arling A. J. Armbruster O. Arnaez H. Arnold Z. P. Arrubarrena Tame G. Artoni H. Asada K. Asai S. Asai N. A. Asbah J. Assahsah K. Assamagan R. Astalos R. J. Atkin M. Atkinson N. B. Atlay H. Atmani P. A. Atmasiddha K. Augsten S. Auricchio A. D. Auriol V. A. Austrup G. Avner G. Avolio K. Axiotis G. Azuelos D. Babal H. Bachacou K. Bachas A. Bachiu F. Backman A. Badea P. Bagnaia M. Bahmani A. J. Bailey V. R. Bailey J. T. Baines C. Bakalis O. K. Baker P. J. Bakker E. Bakos D. Bakshi Gupta R. Balasubramanian E. M. Baldin P. Balek E. Ballabene F. Balli L. M. Baltes W. K. Balunas J. Balz E. Banas M. Bandieramonte A. Bandyopadhyay S. Bansal L. Barak E. L. Barberio D. Barberis M. Barbero G. Barbour K. N. Barends T. Barillari M-S. Barisits T. CPPM Aix-Marseille Université CNRS/IN2P3 Marseille France Homer L. Dodge Department of Physics and Astronomy University of Oklahoma Norman Oklahoma USA II. Physikalisches Institut Georg-August-Universität Göttingen Göttingen Germany Physics Department Brookhaven National Laboratory Upton New York USA Faculté des sciences Université Mohammed V Rabat Morocco Raymond and Beverly Sackler School of Physics and Astronomy Tel Aviv University Tel Aviv Israel Department of Physics Technion Israel Institute of Technology Haifa Israel Department of Physics New York University New York New York USA Departamento de Física Pontificia Universidad Católica de Chile Santiago Chile INFN Gruppo Collegato di Udine Sezione di Trieste Udine Italy ICTP Trieste Italy LAPP Université Savoie Mont Blanc CNRS/IN2P3 Annecy France AGH University of Science and Technology Faculty of Physics and Applied Computer Science Krakow Poland Department of Physics University of Toronto Toronto Ontario Canada Department of Physics Brandeis University Waltham Massachusetts USA Department of Physics Northern Illinois University DeKalb Illinois USA Department of Physics Istanbul University Istanbul Türkiye Département de Physique Nucléaire et Corpusculaire Université de Genève Genève Switzerland Particle Physics Department Rutherford Appleton Laboratory Didcot United Kingdom Santa Cruz Institute for Particle Physics University of California Santa Cruz Santa Cruz California USA CERN Geneva Switzerland Institut de Física d’Altes Energies (IFAE) Barcelona Institute of Science and Technology Barcelona Spain INFN Sezione di Pavia Pavia Italy Dipartimento di Fisica Università di Pavia Pavia Italy Institut für Physik Universität Mainz Mainz Germany Department of Physics Alexandru Ioan Cuza University of Iasi Iasi Romania Departamento de Física Teórica y del Cosmos Universidad de Granada Granada Spain Affiliated with an international laboratory covered by a cooperation agreement

A search for nonresonant Higgs boson pair production in the bb¯bb¯ final state is presented. The analysis uses 126 fb−1 of pp collision data at s=13 TeV collected with the ATLAS detector at the Large Hadron Collider, and targets both the gluon-gluon fusion and vector-boson fusion production modes. No evidence of the signal is found and the observed (expected) upper limit on the cross section for nonresonant Higgs boson pair production is determined to be 5.4 (8.1) times the Standard Model predicted cross section at 95% confidence level. Constraints are placed on modifiers to the HHH and HHVV couplings. The observed (expected) 2σ constraints on the HHH coupling modifier, κλ, are determined to be [−3.5,11.3] ([−5.4,11.4]), while the corresponding constraints for the HHVV coupling modifier, κ2V, are [−0.0,2.1] ([−0.1,2.1]). In addition, constraints on relevant coefficients are derived in the context of the Standard Model effective field theory and Higgs effective field theory, and upper limits on the HH production cross section are placed in seven Higgs effective field theory benchmark scenarios.

关键词： Extensions of Higgs sector Hadron colliders

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Observation of gauge boson joint-polarisation states in W^±Z production from pp collisions at s=13 TeV with the ATLAS detector

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Physics Letters, Section B: Nuclear, Elementary Particle and High-Energy Physics 2023年 843卷

作者： Aad, G. Abbott, B. Abbott, D.C. Abed Abud, A. Abeling, K. Abhayasinghe, D.K. Abidi, S.H. Aboulhorma, A. Abramowicz, H. Abreu, H. Abulaiti, Y. Abusleme Hoffman, A.C. Acharya, B.S. Achkar, B. Adam, L. Adam Bourdarios, C. Adamczyk, L. Adamek, L. Addepalli, S.V. Adelman, J. Adiguzel, A. Adorni, S. Adye, T. Affolder, A.A. Afik, Y. Agapopoulou, C. Agaras, M.N. Agarwala, J. Aggarwal, A. Agheorghiesei, C. Aguilar-Saavedra, J.A. Ahmad, A. Ahmadov, F. Ahmed, W.S. Ai, X. Aielli, G. Aizenberg, I. Akatsuka, S. Akbiyik, M. Åkesson, T.P.A. Akimov, A.V. Al Khoury, K. Alberghi, G.L. Albert, J. Albicocco, P. Alconada Verzini, M.J. Alderweireldt, S. Aleksa, M. Aleksandrov, I.N. Alexa, C. Alexopoulos, T. Alfonsi, A. Alfonsi, F. Alhroob, M. Ali, B. Ali, S. Aliev, M. Alimonti, G. Allaire, C. Allbrooke, B.M.M. Allport, P.P. Aloisio, A. Alonso, F. Alpigiani, C. Alunno Camelia, E. Alvarez Estevez, M. Alviggi, M.G. Amaral Coutinho, Y. Ambler, A. Ambroz, L. Amelung, C. Amidei, D. Amor Dos Santos, S.P. Amoroso, S. Amos, K.R. Amrouche, C.S. Ananiev, V. Anastopoulos, C. Andari, N. Andeen, T. Anders, J.K. Andrean, S.Y. Andreazza, A. Anelli, C.R. Angelidakis, S. Angerami, A. Anisenkov, A.V. Annovi, A. Antel, C. Anthony, M.T. Antipov, E. Antonelli, M. Antrim, D.J.A. Anulli, F. Aoki, M. Aparisi Pozo, J.A. Aparo, M.A. Aperio Bella, L. Aranzabal, N. Araujo Ferraz, V. Arcangeletti, C. Arce, A.T.H. Arena, E. Arguin, J.-F. Argyropoulos, S. Arling, J.-H. Armbruster, A.J. Armstrong, A. Arnaez, O. Arnold, H. Arrubarrena Tame, Z.P. Artoni, G. Asada, H. Asai, K. Asai, S. Asbah, N.A. Asimakopoulou, E.M. Asquith, L. Assahsah, J. Assamagan, K. Astalos, R. Atkin, R.J. Atkinson, M. Atlay, N.B. Atmani, H. Atmasiddha, P.A. Augsten, K. Auricchio, S. Austrup, V.A. Avner, G. Avolio, G. Ayoub, M.K. Azuelos, G. Babal, D. Bachacou, H. Bachas, K. Bachiu, A. Backman, F. Badea, A. Bagnaia, P. Bahrasemani, H. Bailey, A.J. Bailey, V.R. Baines, J.T. Bakalis, C. Baker, O.K. Bakker, P.J. Bakos, E. Bakshi Gupta, D. Balaji, S. Balasubramanian, R. Baldin, E.M. Balek, P. Ballabene Department of Physics University of Adelaide Adelaide Australia Department of Physics University of Alberta Edmonton AB Canada Department of Physics Ankara University Ankara Turkey Division of Physics TOBB University of Economics and Technology Ankara Turkey LAPP Univ. Savoie Mont Blanc CNRS/IN2P3 Annecy France APC Université Paris Cité CNRS/IN2P3 Paris France High Energy Physics Division Argonne National Laboratory Argonne IL United States Department of Physics University of Arizona Tucson AZ United States Department of Physics University of Texas at Arlington Arlington TX United States Physics Department National and Kapodistrian University of Athens Athens Greece Physics Department National Technical University of Athens Zografou Greece Department of Physics University of Texas at Austin Austin TX United States Institute of Physics Azerbaijan Academy of Sciences Baku Azerbaijan Institut de Física d'Altes Energies (IFAE) Barcelona Institute of Science and Technology Barcelona Spain Institute of High Energy Physics Chinese Academy of Sciences Beijing China Physics Department Tsinghua University Beijing China Department of Physics Nanjing University Nanjing China University of Chinese Academy of Science (UCAS) Beijing China Institute of Physics University of Belgrade Belgrade Serbia Department for Physics and Technology University of Bergen Bergen Norway Physics Division Lawrence Berkeley National Laboratory Berkeley CA United States Institut für Physik Humboldt Universität zu Berlin Berlin Germany Albert Einstein Center for Fundamental Physics Laboratory for High Energy Physics University of Bern Bern Switzerland School of Physics and Astronomy University of Birmingham Birmingham United Kingdom Department of Physics Bogazici University Istanbul Turkey Department of Physics Engineering Gaziantep University Gaziantep Turkey Department of Physics Istanbul University Istanbul Turkey Istinye University Sariyer Istanbul Turkey

Measurements of joint-polarisation states of W and Z gauge bosons in W±Z production are presented. The data set used corresponds to an integrated luminosity of 139 fb−1 of proton–proton collisions at a centre-of...

Measurements of joint-polarisation states of W and Z gauge bosons in W^±Z production are presented. The data set used corresponds to an integrated luminosity of 139 fb⁻¹ of proton–proton collisions at a centre-of-mass energy of 13 TeV recorded by the ATLAS detector at the CERN Large Hadron Collider. The W^±Z candidate events are reconstructed using leptonic decay modes of the gauge bosons into electrons and muons. The simultaneous pair-production of longitudinally polarised vector bosons is measured for the first time with a significance of 7.1 standard deviations. The measured joint helicity fractions integrated over the fiducial region are f₀₀=0.067±0.010, f_0T=0.110±0.029, f_T0=0.179±0.023 and f_TT=0.644±0.032, in agreement with the next-to-leading-order Standard Model predictions. Individual helicity fractions of the W and Z bosons are also measured and found to be consistent with joint helicity fractions within the expected amounts of correlation. Both the joint and individual helicity fractions are also measured separately in W⁺Z and W⁻Z events. Inclusive and differential cross sections for several kinematic observables sensitive to polarisation are presented. © 2023

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An application program of fingerprint detection using wavelet transform for authentication 3

An application program of fingerprint detection using wavele...

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3rd Management and Innovation Technology International Conference, MITiCON 2016

作者： Kwaochai, Aunchisa Pongyupinpanich, Surapong Areekul, Pratya San-Um, Wimol Intelligent Electronic System Research Laboratory Faculty of Engineering Thai-Nichi Institute of Technology Pattanakarn 37 Saunlaung Bangkok10250 Thailand Master Program of Forensic Informatics Ramkhamhang University Bangkapi Bangkok10240 Thailand Department of Mathematics Computer Science Chulachomklao Royal Military Academy Province Nakornnayok26001 Thailand

ISBN: (纸本)9781509041053

This paper presents the application program of fingerprint detection using wavelet transform for authentication. Fingerprints are obtained from the site of crime, old documents and excavated things. This paper proposes a fingerprint recognition technique based on wavelet-based texture pattern recognition method. By collecting incomplete fingerprints of 2 people with 6 images each. The original seven of uncompleted fingerprint images were undetected and only one was detected. After enhancing image quality using wavelet transform method, it was found that those of seven images were completed. The comparison method was a matching technique. This work focuses on the ability of the program and knowledge of image processing by studying algorithms of image processing. In design algorithm process, different technique enhancements were employed as well as the study of different of filters and algorithms based on existing research results from literature. © 2016 IEEE.

关键词： Wavelet transforms

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Search for New Phenomena in Final States with Two Leptons and One or No b-Tagged Jets at s=13 TeV Using the ATLAS Detector

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Physical Review Letters 2021年第14期127卷 141801-141801页

作者： G. Aad B. Abbott D. C. Abbott A. Abed Abud K. Abeling D. K. Abhayasinghe S. H. Abidi H. Abramowicz H. Abreu Y. Abulaiti A. C. Abusleme Hoffman B. S. Acharya B. Achkar L. Adam C. Adam Bourdarios L. Adamczyk L. Adamek J. Adelman A. Adiguzel S. Adorni T. Adye A. A. Affolder Y. Afik C. Agapopoulou M. N. Agaras J. Agarwala A. Aggarwal C. Agheorghiesei J. A. Aguilar-Saavedra A. Ahmad F. Ahmadov W. S. Ahmed X. Ai G. Aielli S. Akatsuka M. Akbiyik T. P. A. Åkesson A. V. Akimov K. Al Khoury G. L. Alberghi J. Albert M. J. Alconada Verzini S. Alderweireldt M. Aleksa I. N. Aleksandrov C. Alexa T. Alexopoulos A. Alfonsi F. Alfonsi M. Alhroob B. Ali S. Ali M. Aliev G. Alimonti C. Allaire B. M. M. Allbrooke P. P. Allport A. Aloisio F. Alonso C. Alpigiani E. Alunno Camelia M. Alvarez Estevez M. G. Alviggi Y. Amaral Coutinho A. Ambler L. Ambroz C. Amelung D. Amidei S. P. Amor Dos Santos S. Amoroso C. S. Amrouche C. Anastopoulos N. Andari T. Andeen J. K. Anders S. Y. Andrean A. Andreazza V. Andrei S. Angelidakis A. Angerami A. V. Anisenkov A. Annovi C. Antel M. T. Anthony E. Antipov M. Antonelli D. J. A. Antrim F. Anulli M. Aoki J. A. Aparisi Pozo M. A. Aparo L. Aperio Bella N. Aranzabal V. Araujo Ferraz C. Arcangeletti A. T. H. Arce E. Arena J-F. Arguin S. Argyropoulos J.-H. Arling A. J. Armbruster A. Armstrong O. Arnaez H. Arnold Z. P. Arrubarrena Tame G. Artoni H. Asada K. Asai S. Asai N. A. Asbah E. M. Asimakopoulou L. Asquith J. Assahsah K. Assamagan R. Astalos R. J. Atkin M. Atkinson N. B. Atlay H. Atmani P. A. Atmasiddha K. Augsten S. Auricchio V. A. Austrup G. Avolio M. K. Ayoub G. Azuelos D. Babal H. Bachacou K. Bachas F. Backman A. Badea P. Bagnaia H. Bahrasemani A. J. Bailey V. R. Bailey J. T. Baines C. Bakalis O. K. Baker P. J. Bakker E. Bakos D. Bakshi Gupta S. Balaji R. Balasubramanian E. M. Baldin P. Balek E. Ballabene F. Balli W. K. Balunas J. Balz E. Banas M. Bandieramonte A. Bandyopadhyay L. Barak E. L. Barberio D. Barberis M. Barbero G. Barbour K. N. Barends T. Barillari M-S. Barisits J. Barkeloo T. Barklow B. M. CPPM Aix-Marseille Université CNRS/IN2P3 Marseille France Homer L. Dodge Department of Physics and Astronomy University of Oklahoma Norman Oklahoma USA Department of Physics University of Massachusetts Amherst Massachusetts USA CERN Geneva Switzerland II. Physikalisches Institut Georg-August-Universität Göttingen Göttingen Germany Department of Physics Royal Holloway University of London Egham United Kingdom Physics Department Brookhaven National Laboratory Upton New York USA Raymond and Beverly Sackler School of Physics and Astronomy Tel Aviv University Tel Aviv Israel Department of Physics Technion Israel Institute of Technology Haifa Israel High Energy Physics Division Argonne National Laboratory Argonne Illinois USA Departamento de Física Pontificia Universidad Católica de Chile Santiago Chile INFN Gruppo Collegato di Udine Sezione di Trieste Udine Italy ICTP Trieste Italy Institut für Physik Universität Mainz Mainz Germany LAPP Univ. Savoie Mont Blanc CNRS/IN2P3 Annecy France AGH University of Science and Technology Faculty of Physics and Applied Computer Science Krakow Poland Department of Physics University of Toronto Toronto Ontario Canada Department of Physics Northern Illinois University DeKalb Illinois USA Department of Physics Bogazici University Istanbul Turkey Département de Physique Nucléaire et Corpusculaire Université de Genève Genève Switzerland Particle Physics Department Rutherford Appleton Laboratory Didcot United Kingdom Santa Cruz Institute for Particle Physics University of California Santa Cruz Santa Cruz California USA IJCLab Université Paris-Saclay CNRS/IN2P3 91405 Orsay France Institut de Física d’Altes Energies (IFAE) Barcelona Institute of Science and Technology Barcelona Spain INFN Sezione di Pavia Pavia Italy Dipartimento di Fisica Università di Pavia Pavia Italy Institute for Mathematics Astrophysics and Particle Physics Radboud University/Nikhef Nijmegen Netherlands Department of Physics A

A search for new phenomena is presented in final states with two leptons and one or no b-tagged jets. The event selection requires the two leptons to have opposite charge, the same flavor (electrons or muons), and a large invariant mass. The analysis is based on the full run-2 proton-proton collision dataset recorded at a center-of-mass energy of s=13 TeV by the ATLAS experiment at the LHC, corresponding to an integrated luminosity of 139 fb−1. No significant deviation from the expected background is observed in the data. Inspired by the B-meson decay anomalies, a four-fermion contact interaction between two quarks (b, s) and two leptons (ee or μμ) is used as a benchmark signal model, which is characterized by the energy scale and coupling, Λ and g*, respectively. Contact interactions with Λ/g* lower than 2.0 (2.4) TeV are excluded for electrons (muons) at the 95% confidence level, still far below the value that is favored by the B-meson decay anomalies. Model-independent limits are set as a function of the minimum dilepton invariant mass, which allow the results to be reinterpreted in various signal scenarios.

关键词： Flavor changing neutral currents Quark & gluon jets Leptons Particle data analysis

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Search for Lepton-Flavor Violation in Z-Boson Decays with τ Leptons with the ATLAS Detector

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Physical Review Letters 2021年第27期127卷 271801-271801页

作者： G. Aad B. Abbott D. C. Abbott A. Abed Abud K. Abeling D. K. Abhayasinghe S. H. Abidi H. Abramowicz H. Abreu Y. Abulaiti A. C. Abusleme Hoffman B. S. Acharya B. Achkar L. Adam C. Adam Bourdarios L. Adamczyk L. Adamek J. Adelman A. Adiguzel S. Adorni T. Adye A. A. Affolder Y. Afik C. Agapopoulou M. N. Agaras J. Agarwala A. Aggarwal C. Agheorghiesei J. A. Aguilar-Saavedra A. Ahmad F. Ahmadov W. S. Ahmed X. Ai G. Aielli S. Akatsuka M. Akbiyik T. P. A. Åkesson A. V. Akimov K. Al Khoury G. L. Alberghi J. Albert M. J. Alconada Verzini S. Alderweireldt M. Aleksa I. N. Aleksandrov C. Alexa T. Alexopoulos A. Alfonsi F. Alfonsi M. Alhroob B. Ali S. Ali M. Aliev G. Alimonti C. Allaire B. M. M. Allbrooke P. P. Allport A. Aloisio F. Alonso C. Alpigiani E. Alunno Camelia M. Alvarez Estevez M. G. Alviggi Y. Amaral Coutinho A. Ambler L. Ambroz C. Amelung D. Amidei S. P. Amor Dos Santos S. Amoroso C. S. Amrouche C. Anastopoulos N. Andari T. Andeen J. K. Anders S. Y. Andrean A. Andreazza V. Andrei S. Angelidakis A. Angerami A. V. Anisenkov A. Annovi C. Antel M. T. Anthony E. Antipov M. Antonelli D. J. A. Antrim F. Anulli M. Aoki J. A. Aparisi Pozo M. A. Aparo L. Aperio Bella N. Aranzabal V. Araujo Ferraz C. Arcangeletti A. T. H. Arce E. Arena J-F. Arguin S. Argyropoulos J.-H. Arling A. J. Armbruster A. Armstrong O. Arnaez H. Arnold Z. P. Arrubarrena Tame G. Artoni H. Asada K. Asai S. Asai N. A. Asbah E. M. Asimakopoulou L. Asquith J. Assahsah K. Assamagan R. Astalos R. J. Atkin M. Atkinson N. B. Atlay H. Atmani P. A. Atmasiddha K. Augsten S. Auricchio V. A. Austrup G. Avner G. Avolio M. K. Ayoub G. Azuelos D. Babal H. Bachacou K. Bachas F. Backman A. Badea P. Bagnaia H. Bahrasemani A. J. Bailey V. R. Bailey J. T. Baines C. Bakalis O. K. Baker P. J. Bakker E. Bakos D. Bakshi Gupta S. Balaji R. Balasubramanian E. M. Baldin P. Balek E. Ballabene F. Balli W. K. Balunas J. Balz E. Banas M. Bandieramonte A. Bandyopadhyay L. Barak E. L. Barberio D. Barberis M. Barbero G. Barbour K. N. Barends T. Barillari M-S. Barisits J. Barkeloo T. Bark CPPM Aix-Marseille Université CNRS/IN2P3 Marseille France Homer L. Dodge Department of Physics and Astronomy University of Oklahoma Norman Oklahoma USA Department of Physics University of Massachusetts Amherst Massachusetts USA CERN Geneva Switzerland II. Physikalisches Institut Georg-August-Universität Göttingen Göttingen Germany Department of Physics Royal Holloway University of London Egham United Kingdom Physics Department Brookhaven National Laboratory Upton New York USA Raymond and Beverly Sackler School of Physics and Astronomy Tel Aviv University Tel Aviv Israel Department of Physics Technion Israel Institute of Technology Haifa Israel High Energy Physics Division Argonne National Laboratory Argonne Illinois USA Departamento de Física Pontificia Universidad Católica de Chile Santiago Chile INFN Gruppo Collegato di Udine Sezione di Trieste Udine Italy ICTP Trieste Italy Institut für Physik Universität Mainz Mainz Germany LAPP Univ. Savoie Mont Blanc CNRS/IN2P3 Annecy France AGH University of Science and Technology Faculty of Physics and Applied Computer Science Krakow Poland Department of Physics University of Toronto Toronto ON Canada Department of Physics Northern Illinois University DeKalb Illinois USA Department of Physics Bogazici University Istanbul Turkey Département de Physique Nucléaire et Corpusculaire Université de Genève Genève Switzerland Particle Physics Department Rutherford Appleton Laboratory Didcot United Kingdom Santa Cruz Institute for Particle Physics University of California Santa Cruz Santa Cruz California USA IJCLab Université Paris-Saclay CNRS/IN2P3 91405 Orsay France Institut de Física d’Altes Energies (IFAE) Barcelona Institute of Science and Technology Barcelona Spain INFN Sezione di Pavia Pavia Italy Dipartimento di Fisica Università di Pavia Pavia Italy Institute for Mathematics Astrophysics and Particle Physics Radboud University/Nikhef Nijmegen Netherlands Department of Physics Alexand

A search for lepton-flavor-violating Z→eτ and Z→μτ decays with pp collision data recorded by the ATLAS detector at the LHC is presented. This analysis uses 139 fb−1 of Run 2 pp collisions at s=13 TeV and is combined with the results of a similar ATLAS search in the final state in which the τ lepton decays hadronically, using the same data set as well as Run 1 data. The addition of leptonically decaying τ leptons significantly improves the sensitivity reach for Z→ℓτ decays. The Z→ℓτ branching fractions are constrained in this analysis to B(Z→eτ)<7.0×10−6 and B(Z→μτ)<7.2×10−6 at 95% confidence level. The combination with the previously published analyses sets the strongest constraints to date: B(Z→eτ)<5.0×10−6 and B(Z→μτ)<6.5×10−6 at 95% confidence level.

关键词： Flavor changing neutral currents Particle interactions Particle phenomena Artificial neural networks Gauge bosons W & Z bosons Flavor symmetries Symmetries Particle data analysis

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Design of Decision Support System Determination of Inventory Inventory Using Single Exponential Smoothing Forecasting Method

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Journal of Physics: Conference Series 2018年第1期1114卷

作者： Muhammad Iqbal Dahlan Abdullah H Hartono Cut Ita Erliana S Sriadhi Nurmawati M Adhi Prasnowo Abdurrozzaq Hasibuan Akbar Iskandar Kundharu Saddhono Abdussakir Hastuti Musa Muhammad Ikhsan Setiawan Youmeni Sagala Rumiris Siahaan Eka Mayastika Sinaga Anggraini Syahputri Feby Milanie Henry Aspan Muammar Khaddafi Department of Computer System Universitas Pembangunan Panca Budi Medan Indonesia Department of Informatics Universitas Malikussaleh Aceh Indonesia Department of Computer Science STMIK IBBI Medan Indonesia Department of Industrial Engineering Universitas Malikussaleh Aceh Indonesia Department of Electrical Engineering Universitas Negeri Medan Indonesia Faculty of Industry Technique University of 45 Surabaya Indonesia Department of Industrial Engineering Universitas Maarif Hasyim Latif Sidoarjo Indonesia Faculty of Engineering Universitas Islam Sumatera UtaraMedan-Indonesia Informatics Engineering STMIK AKBA Makassar Indonesia Graduate Program Universitas Sebelas Maret Surakarta Indonesia Department of Mathematics Education State Islamic University of Malang Malang Indonesia Department of Mathematics Universitas Muhammadiyah Parepare Indonesia Department of Civil Engineering Narotama University Surabaya Indonesia STIE Bina Karya Tebing Tinggi Indonesia Universitas Pembangunan Panca Budi Medan Indonesia Department of Accounting Universitas Malikussaleh Aceh Indonesia

The development of information and communication technology at this time has touched all sides of life. Almost no side of human life is not touched by this information technology, which is more synonymous with the world of computerization. No exception also with the computerization that is popular in the corporate environment and government agencies. If in ancient times everything was still done manually. However, at this time all leaders and management have realized the importance of this information technology products that can facilitate them in carrying out the day-to-day corporate functions. Decision Making System of goods purchasing is one of the determinants of the accumulation of goods. If the decision is taken right then stockpiling of goods can be avoided. In this thesis the authors designed a web-based system that helps Management in making the decision of the purchase amount of goods. the system was developed by using Microsoft Visual Studio 2010 and using SQL Server database processing applications. The end result of system design is expected to help minimize the accumulation of goods.

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Analysis of more than 400,000 women provides case-control evidence for BRCA1 and BRCA2 variant classification

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Nature communications 2025年第1期16卷 4852页

作者： Maria Zanti Denise G O'Mahony Michael T Parsons Leila Dorling Joe Dennis Nicholas J Boddicker Wenan Chen Chunling Hu Marc Naven Kristia Yiangou Thomas U Ahearn Christine B Ambrosone Irene L Andrulis Antonis C Antoniou Paul L Auer Caroline Baynes Clara Bodelon Natalia V Bogdanova Stig E Bojesen Manjeet K Bolla Kristen D Brantley Nicola J Camp Archie Campbell Jose E Castelao Melissa H Cessna Jenny Chang-Claude Fei Chen Georgia Chenevix-Trench Don M Conroy Kamila Czene Arcangela De Nicolo Susan M Domchek Thilo Dörk Alison M Dunning A Heather Eliassen D Gareth Evans Peter A Fasching Jonine D Figueroa Henrik Flyger Manuela Gago-Dominguez Montserrat García-Closas Gord Glendon Anna González-Neira Felix Grassmann Andreas Hadjisavvas Christopher A Haiman Ute Hamann Steven N Hart Mikael B A Hartman Weang-Kee Ho James M Hodge Reiner Hoppe Sacha J Howell Anna Jakubowska Elza K Khusnutdinova Yon-Dschun Ko Peter Kraft Vessela N Kristensen James V Lacey Jingmei Li Geok Hoon Lim Sara Lindström Artitaya Lophatananon Craig Luccarini Arto Mannermaa Maria Elena Martinez Dimitrios Mavroudis Roger L Milne Kenneth Muir Katherine L Nathanson Rocio Nuñez-Torres Nadia Obi Janet E Olson Julie R Palmer Mihalis I Panayiotidis Alpa V Patel Paul D P Pharoah Eric C Polley Muhammad U Rashid Kathryn J Ruddy Emmanouil Saloustros Elinor J Sawyer Marjanka K Schmidt Melissa C Southey Veronique Kiak-Mien Tan Soo Hwang Teo Lauren R Teras Diana Torres Amy Trentham-Dietz Thérèse Truong Celine M Vachon Qin Wang Jeffrey N Weitzel Siddhartha Yadav Song Yao Gary R Zirpoli Melissa S Cline Peter Devilee Sean V Tavtigian David E Goldgar Fergus J Couch Douglas F Easton Amanda B Spurdle Kyriaki Michailidou Biostatistics Unit The Cyprus Institute of Neurology & Genetics Nicosia Cyprus. Department of Medical Genetics Oslo University Hospital Oslo Norway. Population Health Program QIMR Berghofer Medical Research Institute Brisbane Queensland Australia. Centre for Cancer Genetic Epidemiology Department of Public Health and Primary Care University of Cambridge Cambridge UK. Department of Quantitative Health Sciences Division of Computational Biology Mayo Clinic Rochester MN USA. Department of Laboratory Medicine and Pathology Mayo Clinic Rochester MN USA. Division of Cancer Epidemiology and Genetics National Cancer Institute National Institutes of Health Department of Health and Human Services Bethesda MD USA. Department of Cancer Prevention and Control Roswell Park Comprehensive Cancer Institute Buffalo NY USA. Fred A. Litwin Center for Cancer Genetics Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital Toronto Ontario Canada. Department of Molecular Genetics University of Toronto Toronto Ontario Canada. Division of Biostatistics Data Science Institute and Cancer Center Medical College of Wisconsin Milwaukee WI USA. Centre for Cancer Genetic Epidemiology Department of Oncology University of Cambridge Cambridge UK. Department of Population Science American Cancer Society Atlanta GA USA. Radiation Oncology Research Unit Hannover Medical School Hannover Germany. Copenhagen General Population Study Herlev and Gentofte Hospital Copenhagen University Hospital Herlev Denmark. Department of Clinical Biochemistry Herlev and Gentofte Hospital Copenhagen University Hospital Herlev Denmark. Faculty of Health and Medical Sciences University of Copenhagen Copenhagen Denmark. Department of Medical Oncology Dana-Farber Cancer Institute Boston MA USA. Department of Internal Medicine and Huntsman Cancer Institute University of Utah Salt Lake City UT USA. Centre for Genomic and Experimental Medicine Institute of Genetics & Cancer The University of Ed

Clinical genetic testing identifies variants causal for hereditary cancer, information that is used for risk assessment and clinical management. Unfortunately, some variants identified are of uncertain clinical significance (VUS), complicating patient management. Case-control data is one evidence type used to classify VUS. As an initiative of the Evidence-based Network for the Interpretation of Germline Mutant Alleles (ENIGMA) Analytical Working Group we analyze germline sequencing data of BRCA1 and BRCA2 from 96,691 female breast cancer cases and 302,116 controls from three studies: the BRIDGES study of the Breast Cancer Association Consortium, the Cancer Risk Estimates Related to Susceptibility consortium, and the UK Biobank. We observe 11,207 BRCA1 and BRCA2 variants, with 6909 being coding, covering 23.4% of BRCA1 and BRCA2 VUS in ClinVar and 19.2% of ClinVar curated (likely) benign or pathogenic variants. Case-control likelihood ratio (ccLR) evidence is highly consistent with ClinVar assertions for (likely) benign or pathogenic variants; exhibiting 99.1% sensitivity and 95.3% specificity for BRCA1 and 93.3% sensitivity and 86.6% specificity for BRCA2. This approach provides case-control evidence for 787 unclassified variants; these include 579 with strong or moderate benign evidence and 10 with strong pathogenic evidence for which ccLR evidence is sufficient to alter clinical classification.

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