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arXiv 2024年

作者： Yaniv, Ziv Anidi, Ifeanyichukwu U. Arakkal, Leanne Arroyo-Mejías, Armando J. Beuschel, Rebecca T. Börner, Katy Chu, Colin J. Clark, Beatrice Clatworthy, Menna R. Colautti, Jake Coscia, Fabian Croteau, Joshua Denha, Saven Dever, Rose Dutra, Walderez O. Fritzsche, Sonja Fullam, Spencer Gerner, Michael Y. Gola, Anita Gollob, Kenneth J. Hernandez, Jonathan M. Hor, Jyh Liang Ichise, Hiroshi Jing, Zhixin Jonigk, Danny Kandov, Evelyn Kastenmüller, Wolfgang Koenig, Joshua F.E. Kothurkar, Aanandita Kortekaas, Rosa K. Kreins, Alexandra Y. Lamborn, Ian T. Lin, Yuri Morais, Katia Luciano Pereira Lunich, Aleksandra Luz, Jean C.S. MacDonald, Ryan B. Makranz, Chen Maltez, Vivien I. McDonough, John E. Moriarty, Ryan V. Ocampo-Godinez, Juan M. Olyntho, Vitoria M. Oxenius, Annette Padhan, Kartika Remmert, Kirsten Richoz, Nathan Schrom, Edward C. Shang, Wanjing Shi, Lihong Shih, Rochelle M. Speranza, Emily Stierli, Salome Teichmann, Sarah A. Veres, Tibor Z. Vierhout, Megan Wachter, Brianna T. Williams, Margaret Zangger, Nathan Germain, Ronald N. Radtke, Andrea J. Bioinformatics and Computational Bioscience Branch National Institute of Allergy and Infectious Diseases National Institutes of Health BethesdaMD United States Critical Care Medicine and Pulmonary Branch National Heart Lung and Blood Institute National Institutes of Health BethesdaMD United States Lymphocyte Biology Section Laboratory of Immune System Biology NIAID NIH BethesdaMD United States Department of Intelligent Systems Engineering Indiana University BloomingtonIN United States UCL Institute of Ophthalmology NIHR Moorfields Biomedical Research Centre London United Kingdom Cambridge Institute for Therapeutic Immunology and Infectious Diseases University of Cambridge Department of Medicine Molecular Immunity Unit Laboratory of Molecular Biology Cambridge United Kingdom McMaster Immunology Research Centre Schroeder Allergy and Immunology Research Institute Department of Medicine Faculty of Health Sciences McMaster University HamiltonON Canada Spatial Proteomics Group Berlin Germany Department of Business Development BioLegend Inc. San DiegoCA United States Functional Immunogenomics Unit National Institute of Arthritis and Musculoskeletal and Skin Diseases National Institutes of Health BethesdaMD United States Laboratory of Cell-Cell Interactions Department of Morphology Institute of Biological Sciences Universidade Federal de Minas Gerais MG Belo Horizonte Brazil Division of Rheumatology Rush University Medical Center ChicagoIL United States Department of Immunology University of Washington School of Medicine SeattleWA United States Robin Chemers Neustein Laboratory of Mammalian Cell Biology and Development The Rockefeller University New YorkNY United States Hospital Israelita Albert Einstein SP Sao Paulo Brazil Surgical Oncology Program National Cancer Institute National Institutes of Health BethesdaMD United States Institute of Pathology Aachen Medical University RWTH Aachen Aachen Germany Hannover Germany Würzburg Institute

The iterative bleaching extends multiplexity (IBEX) Knowledge-Base is a central portal for researchers adopting IBEX and related 2D and 3D immunofluorescence imaging methods. The design of the Knowledge-Base is modeled after efforts in the open-source software community and includes three facets: a development platform (GitHub), static website, and service for data archiving. The Knowledge-Base facilitates the practice of open science throughout the research life cycle by providing validation data for recommended and non-recommended reagents, e.g., primary and secondary antibodies. In addition to reporting negative data, the Knowledge-Base empowers method adoption and evolution by providing a venue for sharing protocols, videos, datasets, software, and publications. A dedicated discussion forum fosters a sense of community among researchers while addressing questions not covered in published manuscripts. Together, scientists from around the world are advancing scientific discovery at a faster pace, reducing wasted time and effort, and instilling greater confidence in the resulting data. © 2024, CC BY.

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WE-173. Combining excitability and connectivity measures from interictal invasive-EEG estimates the epileptogenic zone, even in the absence of frank epileptiform activity

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Clinical Neurophysiology 2022年 141卷 S81-S82页

作者： Billardello, Roberto Ntolkeras, Georgios Pesce, Matthew Harmon, Joseph Hadjinicolaou, Aristides Madsen, Joseph Taffoni, Fabrizio Pearl, Phillip Papadelis, Christos Grant, Ellen Tamilia, Eleonora Fetal-Neonatal Neuroimaging and Developmental Science Center Boston Children’s Hospital Harvard Medical School Boston USA Research Unit of Advanced Robotics and Human-Centred Technologies Department of Engineering University Bio-Medico Campus of Rome Rome Italy Baystate Children's Hospital Springfield USA Division of Epilepsy and Clinical Neurophysiology Department of Neurology Boston Children’s Hospital Harvard Medical School Boston USA Epilepsy Surgery Program Department of Neurosurgery Boston Children’s Hospital Harvard Medical School Boston USA Jane and John Justin Neurosciences Center Cook Children’s Health Care System Fort Worth USA Department of Bioengineering University of Texas at Arlington Arlington USA

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ANTARCTICA AND THE SOUTHERN OCEAN

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BULLETIN OF THE AMERICAN METEOROLOGICAL SOCIETY 2023年第9期104卷 S322-S365页

作者： Clem, Kyle R. Raphael, Marilyn N. School of Geography Environment and Earth Sciences Victoria University of Wellington Wellington New Zealand Scripps Institution of Oceanography University of California San Diego La Jolla California Department of Atmospheric and Oceanic Sciences University of Colorado Boulder Boulder Colorado Earth Science Observation Center Cooperative Institute for Research in Environmental Sciences (ESOC/CIRES) University of Colorado Boulder Boulder Colorado Argentine Naval Hydrographic Service Buenos Aires Argentina Department of Earth and Environmental Science Temple University Philadelphia Pennsylvania Department of Meteorology University of Valparaíso Valparaíso Chile Center for Climate and Resilience Research (CR)2 Santiago Chile British Antarctic Survey Cambridge United Kingdom Science Systems and Applications Inc. Lanham Maryland NASA Goddard Space Flight Center Greenbelt Maryland Royal Netherlands Meteorological Institute (KNMI) DeBilt The Netherlands Department of Marine Sciences University of Gothenburg Gothenburg Sweden Department of Geography Ohio University Athens Ohio NASA Jet Propulsion Laboratory Pasadena California NOAA/OAR Earth System Research Laboratory Global Monitoring Division Boulder Colorado University of Colorado Boulder Boulder Colorado National Oceanography Centre Southampton United Kingdom. Antarctic Meteorological Research and Data Center Space Science and Engineering Center University of Wisconsin-Madison Madison Wisconsin Department of Physical Sciences School of Arts and Sciences Madison Area Technical College Madison Wisconsin Australian Bureau of Meteorology and Institute for Marine and Antarctic Studies (IMAS) University of Tasmania Hobart Australia Earth Science and Observation Center CIRES University of Colorado Boulder Colorado University of St. Andrews St Andrews United Kingdom Princeton University Princeton New Jersey Australian Antarctic Division Australian Antarctic Program Partnership (AAPP) and Australian Centre fo

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Diagnosis of dangerous waste management in Norte de Santander using sandbox-UFPS: overview for sustainability challenges environment and technology 7

Diagnosis of dangerous waste management in Norte de Santande...

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7th IMEKO TC19 Symposium on Environmental Instrumentation and Measurements, EnvIMEKO 2017

作者： Alarcón, Víctor Emmanuel Urbina Rodriguez, Andrea Carreño System Engineering Program Francisco de Paula Santander University Cúcuta N de S Colombia Environment Engineering Program Francisco de Paula Santander University Cúcuta N de S Colombia

ISBN: (纸本)9781510851221

The environment is one of the most important items in the world, therefore policies should be defined for the proper use of environmental resources and disposal of waste. In Colombia in 2005, the environmental policy for the management of dangerous wastes and wastes, and decree 4741, which together with other regulations are compiled in the single regulatory decree of the environmental sector 1076 of 2015, framed within the policies Public services for the management of solid waste and the integral management of RESPEL (dangerous waste). This research aims to diagnose in a general way the current state of the management of dangerous waste in the areas of jurisdiction of CORPONOR as environmental authority of the department of Norte de Santander, taking as sample CORPONOR territorial Cúcuta, defining the methodology of study in stages: planning , Documentary research, field research, elaboration and validation of the diagnostic report and of the information stored by the solid waste coordinator of the corporation, sent by generators and managers using formats [9] RH1, RUA, RESPEL Records, waste management and IDEAM applications [8], as well as management of agrochemicals and hydrocarbons, through the use of office tools and the academic platform for the deployment of web applications called Sandbox- UFPS, which allows to collect, store and process data, generating figures and statistics Of the total waste managed Two and their annual behavior. © 2018 IMEKO-International Measurement Federation Secretariat. All rights reserved.

关键词： Sustainable development

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The Ni isotopic composition of Ryugu reveals a common accretion region for carbonaceous chondrites

arXiv

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arXiv 2024年

作者： Spitzer, Fridolin Kleine, Thorsten Burkhardt, Christoph Hopp, Timo Yokoyama, Tetsuya Abe, Yoshinari Aléon, Jérôme OD. Alexander, Conel M. Amari, Sachiko Amelin, Yuri Bajo, Ken-Ichi Bizzarro, Martin Bouvier, Audrey Carlson, Richard W. Chaussidon, Marc Choi, Byeon-Gak Dauphas, Nicolas Davis, Andrew M. Rocco, Tommaso Di Fujiya, Wataru Fukai, Ryota Gautam, Ikshu Haba, Makiko K. Hibiya, Yuki Hidaka, Hiroshi Homma, Hisashi Hoppe, Peter Huss, Gary R. Ichida, Kiyohiro Iizuka, Tsuyoshi Ireland, Trevor R. Ishikawa, Akira Itoh, Shoichi Kawasaki, Noriyuki Kita, Noriko T. Kitajima, Kouki Komatani, Shintaro Krot, Alexander N. Liu, Ming-Chang Masuda, Yuki Morita, Mayu Moynier, Fréderic Motomura, Kazuko Nakai, Izumi Nagashima, Kazuhide Nguyen, Ann Nittler, Larry Onose, Morihiko Pack, Andreas Park, Changkun Piani, Laurette Qin, Liping Russell, Sara S. Sakamoto, Naoya Schönbächler, Maria Tafla, Lauren Tang, Haolan Terada, Kentaro Terada, Yasuko Usui, Tomohiro Wada, Sohei Wadhwa, Meenakshi Walker, Richard J. Yamashita, Katsuyuki Yin, Qing-Zhu Yoneda, Shigekazu Young, Edward D. Yui, Hiroharu Zhang, Ai-Cheng Nakamura, Tomoki Naraoka, Hiroshi Noguchi, Takaaki Okazaki, Ryuji Sakamoto, Kanako Yabuta, Hikaru Abe, Masanao Miyazaki, Akiko Nakato, Aiko Nishimura, Masahiro Okada, Tatsuaki Yada, Toru Yogata, Kasumi Nakazawa, Satoru Saiki, Takanao Tanaka, Satoshi Terui, Fuyuto Tsuda, Yuichi Watanabe, Sei-Ichiro Yoshikawa, Makoto Tachibana, Shogo Yurimoto, Hisayoshi Max Planck Institute for Solar System Research Justus-von-Liebig-Weg 3 Göttingen37077 Germany Department of Earth and Planetary Sciences Tokyo Institute of Technology Tokyo152-8551 Japan Graduate School of Engineering Materials Science and Engineering Tokyo Denki University Tokyo120-8551 Japan Institut de Minéralogie de Physique des Matériaux et de Cosmochimie Sorbonne Université Museum National d'Histoire Naturelle CNRS UMR 7590 IRD Paris75005 France Earth and Planets Laboratory Carnegie Institution for Science WashingtonDC20015 United States McDonnell Center for the Space Sciences and Physics Department Washington University 35 St. LouisMO63130 United States Geochemical Research Center The University of Tokyo Tokyo113-0033 Japan Guangzhou Institute of Geochemistry Chinese Academy of Sciences GD Guangzhou510640 China Departement of Natural History Sciences Hokkaido University Sapporo001-0021 Japan Centre for Star and Planet Formation Globe Institute University of Copenhagen Copenhagen1350 Denmark Bayerisches Geoinstitut Universität Bayreuth Bayreuth95447 Germany Université Paris Cité Institut de Physique du Globe de Paris CNRS Paris75005 France Department of Earth Science Education Seoul National University Seoul08826 Korea Republic of Department of the Geophysical Sciences Enrico Fermi Institute The University of Chicago 5734 South Ellis Avenue Chicago60637 United States Faculty of Geosciences and Geography University of Göttingen GöttingenD-37077 Germany Faculty of Science Ibaraki University Mito310-8512 Japan ISAS/JSEC JAXA Sagamihara252-5210 Japan Research Center for Advanced Science and Technology The University of Tokyo Tokyo153-8904 Japan Research Institute for Marine Resources Utilization Japan Agency for Marine-Earth Science and Technology Kanagawa237-0061 Japan Departement of Earth and Planetary Sciences Nagoya University Nagoya464-8601 Japan Osaka Application Laboratory SBUWDX Rigaku Corporation Osaka569-1

The isotopic compositions of samples returned from Cb-type asteroid Ryugu and Ivuna-type (CI) chondrites are distinct from other carbonaceous chondrites, which has led to the suggestion that Ryugu/CI chondrites formed in a different region of the accretion disk, possibly around the orbits of Uranus and Neptune. We show that, like for Fe, Ryugu and CI chondrites also have indistinguishable Ni isotope anomalies, which differ from those of other carbonaceous chondrites. We propose that this unique Fe and Ni isotopic composition reflects different accretion efficiencies of small FeNi metal grains among the carbonaceous chondrite parent bodies. The CI chondrites incorporated these grains more efficiently, possibly because they formed at the end of the disk’s lifetime, when planetesimal formation was also triggered by photoevaporation of the disk. Isotopic variations among carbonaceous chondrites may thus reflect fractionation of distinct dust components from a common reservoir, implying CI chondrites/Ryugu may have formed in the same region of the accretion disk as other carbonaceous chondrites. © 2024, CC BY.

关键词： Nickel

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Generation of the anti-Twist crowned helical gear by modifying the gear rotation angle in the hobbing process 2nd

Generation of the anti-Twist crowned helical gear by modifyi...

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2nd International Conference on Machining, Materials and Mechanical Technologies, IC3MT 2016

作者： Hsu, Ruei-Hung Wu, Yu-Ren Chen, Shih-Sheng Bachelor's Program in Precision System Design Feng Chia University Taiwan Department of Mechanical Engineering National Central University Taiwan

ISBN: (纸本)9783035711011

In the gear-hobbing process, the work gear tooth flank is usually longitudinally crowned by varying the center distance between the hob and the work gear. Without crossed angle compensation, however, this center distance variation produces a twisted tooth flank on the work gear. This paper therefore proposes a methodology to reduce this tooth flank twist and achieve anti-Twist in longitudinal crowning by modifying the gear rotation angle in the hobbing process which is practiced using a CNC hobbing machine with three synchronous axes. © 2017 Trans Tech Publications, Switzerland.

关键词： Helical gears

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Sustained tenascin-C expression drives neointimal hyperplasia and promotes aortocaval fistula failure

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American Journal of Physiology - Heart and Circulatory Physiology 2025年第6期328卷 H1147-H1167页

作者： Gonzalez, Luis A. Zhang, Weichang Bai, Hualong Taniguchi, Ryosuke Ramachandra, Abhay B. Jovin, Daniel G. Ohashi, Yuichi Nguyen, Mytien Thaxton, Carly Yatsula, Bogdan Vazquez-Padron, Roberto I. Humphrey, Jay D. Martin, Kathleen A. Kyriakides, Themis R. Dardik, Alan Yale School of Medicine New Haven CT United States Vascular Biology and Therapeutics Program Yale School of Medicine New Haven CT United States Department of Cellular and Molecular Physiology Yale University New Haven CT United States Department of Surgery Yale School of Medicine New Haven CT United States Division of Vascular Surgery Department of Surgery The University of Tokyo Tokyo Japan Department of Biomedical Engineering Yale University New Haven CT United States DeWitt Daughtry Family Department of Surgery Leonard M. Miller School of Medicine University of Miami Miami FL United States Section of Cardiovascular Medicine Yale School of Medicine New Haven CT United States Department of Pathology Yale University New Haven CT United States Department of Surgery Veterans Affairs Connecticut Healthcare System West Haven CT United States Department of Cardiovascular Surgery Jichi Medical University Saitama Medical Center Saitama Japan Department of Surgery Icahn School of Medicine at Mount Sinai New York NY United States

End-stage kidney disease (ESKD) impacts over 740,000 individuals in the United States, with many patients relying on arteriovenous fistulae (AVF) for hemodialysis due to superior patency and reduced infections. However, AVF patency is reduced by thrombosis and neointimal hyperplasia, yielding a 1-yr patency of only 40%–50%. We hypothesized that tenascin-C (TNC), a regulator of inflammation and immune responses after injury, also regulates venous remodeling during AVF maturation. AVF were created in wild-type (WT) and Tnc knockout (Tnc^-/-) mice, and proteomic analyses were conducted to identify protein changes between sham and AVF WT tissue. Immunofluorescence and Western blot assays compared venous tissue from WT and Tnc^-/- mice. In vitro studies using human umbilical vein endothelial cells and human umbilical vein smooth muscle cells examined TNC-siRNA effects on thrombomodulin (THBD) and NF-κB. Macrophages from WT and Tnc^-/- mice were assessed for anti-inflammatory phenotype polarization and tissue factor expression. TNC expression was spatially and temporally regulated in WT mice with AVF, and TNC colocalized with matrix remodeling but not with THBD expression;TNC expression was downregulated in patent AVF but sustained in occluded AVF, both in WT mice and human AVF specimens. Tnc^-/- mice had reduced AVF patency, less wall thickening, and increased thrombosis, with increased THBD expression. In vitro, TNC-siRNA increased THBD and reduced NF-κB activation. Macrophages from Tnc^-/- mice showed increased anti-inflammatory macrophage polarization and tissue factor expression, facilitating thrombosis. Sustained TNC expression drives neointimal hyperplasia and AVF failure by promoting a prothrombotic, inflammatory microenvironment. Targeting TNC pathways may enhance AVF patency and improve dialysis outcomes. © 2025 The Authors.

关键词： arteriovenous fistulae tenascin-C thrombomodulin thrombosis venous remodeling

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Comprehensive High Impedance Fault Model for Real-Time Environment

Comprehensive High Impedance Fault Model for Real-Time Envir...

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Annual Conference of Industrial Electronics Society

作者： Aldair Wontroba Adriano Peres de Morais Jean Pereira Rossini Mairon Gallas Ghendy Cardoso João Paulo Abreu Vieira Marcelo Costa Santos Patrick Escalante Farias Federal University of Santa Maria Santa Maria RS Brazil Federal University of Santa Maria Santa Maria Brazil Electrical Engineering Graduate Program Federal university of Pará Belém PA Brazil Distribution System Operation Management CELPA –Electric Distribution Utility of Pará Belém PA Brazil Federal Institute of Education Science and Technology of Rio Grande do Sul IFRS Farroupilha Brazil

This paper presents a comprehensive high impedance fault model for real-time environment. This model offers different types of ground surface and high impedance faults. Experimental results show that it is suitable for relays and algorithms commissioning in closed loop environment. The model is incorporated into OPAL-RT simulator and implemented in Hypersim software. Finally, the performance of the model is validated under a real case of high impedance fault by comparison with real-time simulation.

关键词： Circuit faults Real-time systems Fault currents Impedance Resistance Power cables Surface impedance

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Improvements on Interpolation Techniques based on Linear programming for Constrained Control

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IFAC-PapersOnLine 2017年第1期50卷 1403-1408页

作者： Rubin D. Mercader P. Nguyen H.-N. Gutman P.-O. Baños A. Autonomous Systems Program Technion – Israel Institute of Technology Haifa Israel Department of Computer and System Engineering University of Murcia Murcia Spain Control Signal and System Department IFP Energies Nouvelles Lyon France Faculty of Civil and Environmental Engineering Technion – Israel Institute of Technology Haifa Israel

We present some improvements on interpolation based control (IC) for linear discrete-time systems with polyhedral constraints on the control and the states variables. The plant may be uncertain, time-varying, and subject to bounded disturbances. Roughly speaking, IC approach is based on the interpolation between an inner and an outer controller. The extension presented here is twofold. On the one hand, the IC approach is extended to deal with higher order inner controllers, making it e.g. possible to incorporate integral action in a vicinity of the origin. On the other hand, this paper presents a modification that better exploits the control signal range. As with previous IC strategies, the presented method demands relatively low online computational resources, and is applicable also to uncertain plants. The benefits of the improved scheme are illustrated in some examples. © 2017

关键词： Constrained control Linear programing Model predictive optimization-based control Robust control Time-varying systems

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Surface tension assisted dynamic and uniform size generation of 3D spherical hydrogels (STA-DUH) 22

Surface tension assisted dynamic and uniform size generation...

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22nd International Conference on Miniaturized systems for Chemistry and Life Sciences, MicroTAS 2018

作者： Koduri, Manohar Prasad Garden, Tom Hunt, John A. Henstock, James Curran, Judith Tseng, Fan-Gang International Intercollegiate PhD Program NTHU Hsinchu Taiwan Department of Mechanical Materials and Aerospace School of Engineering University of Liverpool United Kingdom School of Science and Technology Nottingham Trent University NottinghamNG11 8NS United Kingdom Institute of Ageing and Chronic Disease William Henry Duncan Building University of Liverpool United Kingdom Engineering and System Science Frontier Research Center on Fundamental and Applied Sciences of Matters National Tsing Hua University Taiwan

ISBN: (纸本)9781510897571

Technologies like additive manufacturing, microfluidics, and electrospray show a possibility of generating a variety of 3-Dimensional structures but seriously suffer in adapting and utilizing the wide variety of available biocompatible materials because of innate diverse physical and chemical properties of biomaterials. It is very important to have a technology which can be viable and dynamically adaptable for different types of materials in generating uniform structures. This work presents a novel cell-laden hydrogel generation using the surface tension phenomenon in controlling the size of the hydrogel. Copyright © (2018) by Chemical and Biological Microsystems Society. All rights reserved.

关键词： Surface tension

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