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Data Mining: The Classification Method to Predict the Types of Motorcycle Spare Parts to be Restocked

IOP Conference Series: Materials science and engineering 2019年第2期662卷

作者： S L B Ginting Y R Ginting Sutono A Rakhman Computer System Study Program Faculty of Engineering and Computer Science Universitas Komputer Indonesia Jl. Dipati Ukur 112-116 Bandung 40132 Indonesia Department of Mechanical Engineering Universitas Riau Kampus Bina Widya KM 12 5 Simpang Baru Pekanbaru 28293 Indonesia

The research intends to create an application which is able to analyse sales data in a motorcycle company to predict the types of spare parts which should be stocked. This prediction is crucial since problems are often encountered while restocking. For instance, when there have been some imprecisions occurring in deciding regarding the types of spare parts to restock, the spare parts accumulate. It can cause inefficiency in terms of storage, the products quality deteriorates due to having been stored for too long, and sometimes the best-selling products are not available in the warehouse. This application is developed with Naïve Bayes Classifier (NBC) method which has a high accuracy in predicting future occurrences. This method works by calculating the probability value in each attribute class and determining the optimal probability value. From the test results, 4500 training data with 200 sample test data has 90% similarity with the results of the restock decision without application. For 500 test data, the similarity was 96%. It is proven that this method has a high accuracy so that it can help the decision makers solved the company problem in predicting the types of motorcycle parts to be restocked.

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AIR-CUSHION LANDING CRAFT NAVIGATION

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NAVAL ENGINEERS JOURNAL 1985年第4期97卷 248-260页

作者： GRAHAM, HR KIM, JC BAND, EGU FOWLER, AW Herbert R. Graham:received his degrees of B.S. in 1951 and M.S. in 1958 in aeronautical engineering from the Massachusetts Institute of Technology and the California Institute of Technology respectively. He also attended the Harvard Graduate School of Business Administration. He is presently a task manager at TRW Inc. McLean Virginia responsible for landing craft air cushion (LCAC) engineering support. Since joining TRW in 1967 he has had several technical project management and system engineering responsibilities in amphibious ships transportation and energy. He was responsible for the preliminary engineering design and cost estimates for tracked air cushion vehicles (TACVs). He has been active in several professional societies including ASNE and served as vice-chairman Los Angeles Section American Institute of Aeronautics and Astronautics. John C. Kim:received his degrees of B.S. in electrical engineering Tri-State University 1959 M.S. in electrical engineering Michigan State University 1960 and Ph.D. in electrical engineering Michigan State University. He is presently a senior staff engineer with TRW Inc. McLean Virginia where his technical experience has included communications system engineering and navigation system analysis. Since joining TRW in 1969 he has held numerous positions including section head project manager and department manager. His previous employment includes E-Systems/Melpar Division and Honeywell. Dr. Kim has been active in the IEEE Washington Chapter activities which included secretary vice-chairman and chairman of Systems Science and Cybernetics Group. Edward G.U. Band:received a B.S. degree in mechnical engineering in 1946 and a D.I.C in aeronautical engineering in 1947 at the City and Guilds College of London University. In 1951 he received an M.S. degree from Stevens Institute of Technology in fluid dynamics. After a career in the aircraft industry in England Canada and the U.S.A. he spent several years teaching in Chile and at Webb Institute of Naval Archi

Air cushion vehicles (ACVs) have operated successfully on commercial routes for about twenty years. The routes are normally quite short; the craft are equipped with radar and radio navigation aids and maintain continuous contact with their terminals. Navigation of these craft, therefore, does not present any unusual difficulty. The introduction of air cushion vehicles into military service, however, can present a very different picture, especially when external navigation aids are not available and the craft must navigate by dead reckoning. This paper considers the problems involved when navigating a high-speed air cushion vehicle by dead reckoning in conditions of poor visibility. A method is presented to assess the ACV's navigational capability under these circumstances. A figure of merit is used to determine the sensitivity of factors which affect navigation such as the range of visibility, point-to-point distance, speed, turning radius and accuracy of onboard equipment. The method provides simplistic but adequate answers and can be used effectively to compare the-capability and cost of alternative navigation concepts.

关键词： AIR CUSHION VEHICLES

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PRMT5 promotes full-length HTT expression by repressing multiple proximal intronic polyadenylation sites

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Nucleic Acids Research 2025年第8期53卷 gkaf347页

作者： Yadav, Manisha Alqazzaz, Mona A. Ciamponi, Felipe E. Ho, Jolene C. Maron, Maxim I. Sababi, Aiden M. Macleod, Graham Ahmadi, Moloud Bullivant, Garrett Tano, Vincent Langley, Sarah R. Sánchez-Osuna, María Sachamitr, Patty Kushida, Michelle Bardile, Costanza Ferrari Pouladi, Mahmoud A. Kurtz, Rebecca Richards, Laura Pugh, Trevor Tyers, Mike Angers, Stephane Dirks, Peter B. Bader, Gary D. Truant, Ray Massirer, Katlin B. Barsyte-Lovejoy, Dalia Shechter, David Harding, Rachel J. Arrowsmith, Cheryl H. Prinos, Panagiotis Department of Medical Biophysics University of Toronto Toronto M5G1L7 ON Canada Princess Margaret Cancer Centre University Health Network Toronto M5G1L7 ON Canada Structural Genomics Consortium University of Toronto Toronto M5G1L7 ON Canada Center for Molecular Biology and Genetic Engineering University of Campinas (UNICAMP) Campinas 13083-872 Brazil Department of Biochemistry Albert Einstein College of Medicine Bronx 10461 NY United States Donnelly Centre for Cellular and Biomolecular Research University of Toronto Toronto M5S3E1 ON Canada Department of Molecular Genetics University of Toronto Toronto M5S3E1 ON Canada Leslie Dan Faculty of Pharmacy University of Toronto Toronto M5S3M2 ON Canada Developmental and Stem Cell Biology Program Arthur and Sonia Labatt Brain Tumor Research Centre The Hospital for Sick Children Toronto M5G0A4 ON Canada Lee Kong Chian School of Medicine Nanyang Technological University Singapore 636921 Singapore School of Biosciences Cardiff University Cardiff CF103AX United Kingdom Institute for Research in Immunology and Cancer Universitéde Montréal Montreal H3C3J7 QC Canada Department of Medical Genetics Centre for Molecular Medicine and Therapeutics Djavad Mowafaghian Centre for Brain Health British Columbia Children's Hospital Research Institute University of British Columbia Vancouver V5Z4H4 BC Canada Department of Biochemistry and Biomedical Sciences McMaster University Hamilton L8N3Z5 ON Canada Ontario Institute for Cancer Research University Health Network Toronto M5G0A3 ON Canada Division of Neurosurgery Department of Surgery University of Toronto Toronto M5S1A8 ON Canada Department of Laboratory Medicine and Pathobiology University of Toronto Toronto M5S1A8 ON Canada Lunenfeld-Tanenbaum Research Institute Sinai Health System Toronto M5G1X5 ON Canada Department of Computer Science University of Toronto M5S3E1 ON Canada Department of Pharmacology and Toxicology University of Toronto

Expansion of the CAG trinucleotide repeat tract in exon 1 of the Huntingtin (HTT) gene causes Huntington's disease (HD) through the expression of a polyglutamine-expanded form of the HTT protein. This mutation triggers cellular and biochemical pathologies, leading to cognitive, motor, and psychiatric symptoms in HD patients. Targeting HTT splicing with small molecule drugs is a compelling approach to lowering HTT protein levels to treat HD, and splice modulators are currently being tested in the clinic. Here, we identify PRMT5 as a novel regulator of HTT messenger RNA (mRNA) splicing and alternative polyadenylation. PRMT5 inhibition disrupts the splicing of HTT introns 9 and 10, leading to the activation of multiple proximal intronic polyadenylation sites within these introns and promoting premature termination, cleavage, and polyadenylation of the HTT mRNA. This suggests that HTT protein levels may be lowered due to this mechanism. We also detected increasing levels of these truncated HTT transcripts across a series of neuronal differentiation samples, which correlated with lower PRMT5 expression. Notably, PRMT5 inhibition in glioblastoma stem cells potently induced neuronal differentiation. We posit that PRMT5-mediated regulation of intronic polyadenylation, premature termination, and cleavage of the HTT mRNA modulates HTT expression and plays an important role during neuronal differentiation. © 2025 The Author(s).

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Applying fuzzy functions and sequential coordination to optimization of machinery arrangement and pipe routing

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NAVAL ENGINEERS JOURNAL 1998年第6期110卷 43-54页

作者： Wu, BC Young, GS Schmidt, W Choppella, K Dr. Bi-Chu Wu:received a PhD in Mechanical Engineering from the University of Maryland College Park in 1991. She has worked on projects involving naval architecture design optimization solid mechanics and database development. Presently a senwr engineer with Angle Incorporated Dr Wu's research interests are in design optimization and fuzzy logic applications. Dr. Gin-Shu Young: a senior engineer with Angle Incorporated holds a PhD in Mechanical Engineering from the University of Maryland College Park. As a guest researcher with National Institute of Standards and Technologies from 1990 to 1993 he worked on vision-based navigation for autonomous vehicles. His experience also includes applications of optimization fuzzy logic neural network and genetic algorithm methods to engineering system design Mr. William Schmidt:co-founded Angle Incorporated in 1990 and has served as Vice PresidentlChiefScientist during this tame. He holds a B.Sc. in Applied Science from the Naval Acadt?my and an M.Sc. in Physics from the Naval Post Graduate School. He has cner 20 years experience in technical leadership material and personnel management. He has led the application of computer aided design (CAD) and Product Model Information Exchange to the shipbuilding industry. His experience also includes leading the amlication of model based operational analysis to support the Live Fire Test Program for DDG 51 Class Destroyers. Mr. Krishna M. Choppella:is a Sofware Engineer at Eidea Laboratories Incotporated where he works on componentbased distributed enterpvise frameworks. He has been involved in creating data analysis tools for the US Nay by integrating CAD modeis databases and graphical front ends. His work in the Masters degree program in Mechanical Engineering at the University of Texas at Austin was in di0ddase.r spectroscopy of combustion products in porous-matri burners. He received his Bachelors degree in Electrical Engineering in India. He was a Research Associate at the Centre for Laser Technology and Project Engi

Ship design is often multidisciplinary involving several design elements with various types of objectives and constraints (O/C) some easily described as mathematical formulas, others better modeled as descriptive assertions. This paper describes a method based on fuzzy functions and an integrated performance index to model O/C using descriptive assertions to be used with mathematical formulas in optimization. Another issue addressed in this paper concerns the coordination of design elements when sequentially coupled, that is, when one leads the other and the performance of the follower depends greatly on the design of the leader. Based on neuro-fuzzy techniques, the method described here coordinates and optimizes sequentially coupled elements. The two methods are applied to machinery arrangement (MA) and pipe routing (PR). Preliminary models for optimization of MA and PR are described considering convenience, producibility: engine room size, interference and location as factors in the O/C set. Some test results from MA/PR applications are presented and discussed. The methods are generic and can be extended to other elements in ship design. They are mutually independent and may be used separately Two advantages of their use are an improvement in overall performance and a reduction in the need for redesign of elements.

关键词： Optimization

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computer-AIDED-DESIGN METHODS FOR PROPELLER FILLET GAUGES

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NAVAL ENGINEERS JOURNAL 1990年第3期102卷 202-208页

作者： ALLEN, DW VINOSKI, WS OVERTON, BA David W. Allen:is a senior computer scientist at the Machinery Technology Division Westinghouse Electric Corporation Large Pa. He received the B.A. degree in mathematics from Grinnell College and the M.S. degree in computer science from the University of Pittsburgh. His career with Westinghouse has been divided between assignments in engineering and computer applications. Mr. Allen has published eight technical papers. He received the George Westinghouse Signature A ward of Excellence for his work on the development of the GAGES computer program for designing propeller gages. He is a member of the Association for Computing Machinery (ACM) and the Institute of Electrical and Electronics Engineers (IEEE). Walter S. Vinoski:is a project engineer at the Machinery Technology Division Westinghouse Electric Corporation Large Pa. and was instrumental in the development of the GAGES computer program. He was awarded the George Westinghouse Signature Award of Excellence for his work on the GAGES program. Mr. Vinoski has six years of marine propulsion system experience specifically with propellers. He earned a B.S. degree in electronics engineering and minored in mathematics at the Ohio Institute of Technology. He is a member of the American Society of Naval Engineers. Bernard A. Overton:graduated from North Carolina Agricultural and Technical State University Greensboro N.C. in 1958 with a B.S. degree in mechanical engineering. Within two years of joining the U.S. Army Mr. Overton was honorably discharged as a first lieutenant. Mr. Overton worked seven years at Philadelphia Naval Shipyard in the following areas: shafting shafting alignment bearing reactions noise and vibration surveys propellers and propeller blade gage designs. In 1967 Mr. Overton transferred to the Navy Engineering Center. He has worked on main propulsion devices such as water jets propellers (both submarine and surface ship) and propeller blade gages. Mr. Overton was responsible for the establishment of the Naval Inspectors Propeller Certif

One of the most complicated forms encountered in engineering design is that of the marine propeller. The complexities arise from the complicated hydrodynamic surfaces of the propeller blades and the complicated manner in which the blades are oriented with and attached to the hub. Where propeller blades are attached to the hub, the blade shape is blended into the shape of the hub. The geometry of this region is particularly complicated. The shape of the blend is called a fillet, and the blending region is called the fillet region. Sheet metal gages conforming to various blade surface contours are used in the manufacture and inspection of propellers. Five different types of gages define the shape of the propeller in different regions. Fillet gages are such gages that define the shape of propeller blades in the fillet region. This paper describes a new computer-aided method for designing fillet gages. Previous methods of fillet gage design required the designer to follow a complicated layout procedure of determining where a particular unfilleted blade contour intersected the hub. The design of the fillet was then done in another layout procedure. Newly developed numerical procedures incorporated in a computer program have reduced the time required to design a complete set of gages (including fillet gages) from up to several weeks to hours.

关键词： Propellers

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Alert and Response of Earthquake and Tsunami for Community Based Disaster Risk Reduction

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Journal of Physics: Conference Series 2021年第1期1811卷

作者： Rr M I Retno Susilorini Andre Kurniawan Pamudji Ridwan Sanjaya Amrizarois Ismail Ardhito Hayyu Amasto Department of Infrastructure and Environmental Engineering Faculty of Environmental Science and Technology Soegijapranata Catholic University Semarang Master Program of Environmental and Urban Studies Faculty of Environmental Science and Technology Soegijapranata Catholic University Semarang Department of Information System Faculty of Computer Science Soegijapranata Catholic University Semarang

Indonesia had been suffered by earthquake and tsunami for many centuries. Since many lives have taken by tsunami strikes, alert and response system are very important as important part of Disaster Risk Reduction, especially in area with high population density. This research conducted in Kangkung fishing village in Bandar Lampung coastal area which is an earthquake and tsunami prone area. The aim of the research is to study alert and response of Community Based Disaster Risk Reduction. The research conducted by qualitative method and purposive-descriptive approach. There were 53 respondents which participated in the survey and interview. It is reported that 'Smart Resilient City' model suitable for community needs of alert and response of earthquake and tsunami disaster. This research meets conclusion that 'Smart Resilient City' model may become a great solution in Community Based Disaster Risk Reduction to cope with the hazard of earthquake and tsunami comprehensively and sustainably.

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The Application of Fuzzy Logic Method in the Debtors Eligibility Assessment system of Microfinance Institution

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IOP Conference Series: Materials science and engineering 2020年第1期879卷

作者： S L B Ginting M R M Rizky Y R Ginting Sutono Computer System Study Program Faculty of Engineering and Computer Science Universitas Komputer Indonesia Jl. Dipati Ukur 112-116 Bandung 40132 Indonesia. Department of Mechanical Engineering Universitas Riau Kampus Bina Widya KM 125 Simpang Baru Pekanbaru 28293 Indonesia.

Decision-making processes in determining loan eligibility are often subjective which leads to imprecise credit predictions. Due to inaccurate inquiry on prospective customers done by field survey officers of Bank Perkreditan Rakyat (BPR) Bandung City, it has experienced credit complications such as bad credits. Therefore, this study aims to help decision-makers in determining creditworthiness and preventing bad credits from occurring. To realize this solution, the study uses the Fuzzy Logic method to calculate the creditworthiness of each prospective loaner based on the inquiries done in the field survey. Fuzzy Logic is known to be a 'counting' methodology with varying words. In addition, it can implement human expertise into machine language with ease and adequately. Based on numerous testing performed, the results demonstrate a level of 90% in accuracy when inputting within the valid ranges of each fuzzy set and membership function. However, the level of accuracy is only based on the clarification result which is determined by a researcher and BPR director, not a general level of accuracy for other microfinance institutions. Nevertheless, the findings of this study prove the method has a high enough accuracy to support decision-makers in determining the loan eligibility of prospective loaners and through this application in the surveying process, survey workers can work more efficiently. Hence, in future has a higher chance of predicting bad credits from potential loaners.

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Wildlife-microbiome interactions and disease: exploring opportunities for disease mitigation across ecological scales

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Drug Discovery Today: Disease Models 2018年 28卷 105-115页

作者： Williams, Candace L. Caraballo-Rodríguez, Andrés Mauricio Allaband, Celeste Zarrinpar, Amir Knight, Rob Gauglitz, Julia M. Institute for Conservation Research San Diego Zoo Global United States Collaborative Mass Spectrometry Innovation Center Skaggs School of Pharmacy and Pharmaceutical Sciences University of California La Jolla San Diego 92307 CA United States Biomedical Sciences Graduate Program University of California La Jolla San Diego 92307 CA United States Department of Medicine University of California La Jolla San Diego 92307 CA United States Veterans Affairs San Diego Healthcare System San Diego California University of California La Jolla San Diego 92307 CA United States Department of Pediatrics University of California La Jolla San Diego 92037 CA United States Department of Bioengineering University of California La Jolla San Diego 92093 CA United States Department of Computer Science and Engineering University of California La Jolla San Diego 92093 CA United States Center for Microbiome Innovation University of California La Jolla San Diego 92307 CA United States

Captive wildlife are a unique set of animals, whose diverse host–microbe symbioses are underexplored. Compared to their wild counterparts they are particularly susceptible to a variety of diseases, many of which have explicit or purported links to the microbiome. In this perspective, we will examine how the microbiome influences gastrointestinal disorders, metabolic dysregulation, reproduction, and disease susceptibility in captive wildlife. Investigation of wildlife, and specifically captive wildlife, affords a unique opportunity to gain understanding of the broad diversity of the associated microbiota and learn from nature's molecular and microbial responses to disease. Studies like these could lead to the discovery of new interventions, ranging from dietary changes to the use of microbes or their natural products as treatment. Intervention strategies can lead to the discovery of medically relevant small molecules and the development of a novel platform for N-of-1 targeted medical investigations. © 2019 Elsevier Ltd

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Pale Red Dot: A Large, Robust Architecture for Human Settlements on Mars

Pale Red Dot: A Large, Robust Architecture for Human Settlem...

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Accelerating Space Commerce, Exploration, and New Discovery Conference, ASCEND 2023

作者： Lordos, George Hoying, Madelyn McKinney, Lanie Webb, Alisa Lin, Yuying Martin, Estelle Beilstein, John Miller, Duncan Villegas, David Sepulveda, Francisco AlSadah, Yousif Iyer, Divya O’Neill, Cormac Patel, Palak Garcia, Ignacio Arzuaga Azzouz, H. Chan, Wing Lam Eyre, Ezra Gleason, Dane Romero, Elizabeth Arias, Liliana Orozco, Omar Gentgen, Chloe Latyshev, Kir Hoffman, Jeffrey de Weck, Olivier Ikinci, Meltem Lordos, Alexandros Aeronautics and Astronautics Massachusetts Institute of Technology 33-409 CambridgeMA02139 United States Massachusetts Institute of Technology Harvard-MIT Health Sciences and Technology Program and MIT Aeronautics and Astronautics 33-409 CambridgeMA02139 United States Massachusetts Institute of Technology CambridgeMA02139 United States Aeronautics and Astronautics Massachusetts Institute of Technology 77 Mass Ave. 33-409 CambridgeMA02139 United States System Design and Management Massachusetts Institute of Technology 77 Mass Ave. E40-300 CambridgeMA02139 United States Mechanical Engineering Massachusetts Institute of Technology 77 Mass Ave. 33-409 CambridgeMA02139 United States Civil and Environmental Engineering Massachusetts Institute of Technology 77 Mass Ave. CambridgeMA02139 United States Electrical Engineering Massachusetts Institute of Technology 77 Mass Ave. CambridgeMA02139 United States Nuclear Science and Engineering Massachusetts Institute of Technology 77 Mass Ave. CambridgeMA02139 United States Computer Science and Engineering Massachusetts Institute of Technology 77 Mass Ave. CambridgeMA02139 United States Massachusetts Institute of Technology 77 Mass Ave. 37-219 CambridgeMA02139 United States Massachusetts Institute of Technology 77 Mass Ave. 33-410 CambridgeMA02139 United States Behavioral Economics University of Cyprus Nicosia Cyprus Department of Psychology University of Cyprus Nicosia Cyprus

ISBN: (数字)9781624107054

ISBN: (纸本)9781624107054

We propose a ten-yearMars mission to establish Earth-independence and support efficient, safe, and sustainable science and exploration goals. The campaign begins with a series of precursor missions, starting with the Artemis program, followed by robotic missions to performsite surveys and selection, de-risk technologies, and to start stockpiling in-situ water and propellant. Robotic Cargo Starships would depart first in 2035 to deliver and deploy approximately 5,800 tons of habitats, nuclear microreactors, farmmodules, manufacturing and ISRU systems. In 2040, two Crew Starships carrying 36 persons would land onMars to establish two close-proximity villages. The lifecycle cost is estimated at $81 billion, with a peak annual cost of $6.6 billion. To meet RASC-AL competition requirements, intended to motivate the exploration of highly self-reliant architecture concepts, resupply from Earth was constrained to only 5 metric tons every two years and minimum surface endurance was set at 7 years. The risks to human life and to critical systems increase exponentially over a minimally-resupplied, 7-10 year mission toMars. Our approach focused on identifying capabilities to mitigate known and unknown risks. Using a high-fidelity crew time model, we found that large architectures, with their economies of scale and productivity gains from specialization, are essential to robustly support the necessary capabilities. The model also shows that small 7-year missions of 12 persons or less cannot provide value in terms of free surface traverse time for science and exploration. Given the necessity of a large, complex architecture, we then sought out efficiencies and synergies (value engineering) in order to make the mission feasible and affordable. In the process, we identified more benefits that are enabled only by large missions, including the creation of a true community on Mars with sufficient social complexity for humans to thrive, and the geopolitically compelling option to inclu

关键词： Value engineering

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Chitosan for Biofunctionalization of Microsystems

Chitosan for Biofunctionalization of Microsystems

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IEEE/NLM Life science systems and Applications Workshop

作者： Stephan T. Koev Michael A. Powers Vlad Badilita Hyunmin Yi William E. Bentley Gregory F. Payne Gary W. Rubloff Reza Ghodssi Institute for Systems Research ISR University of Maryland College Park MD USA University System of Maryland Adelphi MD US Department of Materials Science and Engineering University of Maryland College Park MD USA Department of Chemical Engineering University of Maryland College Park MD 20742 University of Maryland Biotechnology Institute (UMBI) University of Maryland College Park MD 20742 Bioengineering Graduate Program University of Maryland College Park MD 20742 University of Maryland College Park MD USA University of Maryland Biotechnology Institute College Park MD USA Institute for Systems Research (ISR) University of Maryland College Park MD 20742 Department of Materials Science and Engineering University of Maryland College Park MD 20742 Department of Electrical and Computer Engineering University of Maryland College Park MD 20742 Institute for Systems Research (ISR) University of Maryland College Park MD 20742

ISBN: (纸本)1424402778

We present the use of the polysaccharide chitosan for immobilizing biomolecules on microfabricated device surfaces. The main advantages of chitosan are its abundance of primary amine groups and its ability to be electrodeposited. Biomolecules are easily attached to chitosan 's amines by standard glutaraldehyde chemistry. The electrodeposition of chitosan allows accurate spatial and temporal control of biomolecule placement. We have demonstrated this biofunctionalization method for two different bioMEMS devices: a biophotonic sensor and a micromechanical biosensor. We have successfully assembled probe DNA on each of them and detected hybridization with target DNA as a demonstration of sensor operation. Here, we briefly present the fabrication procedure and testing results for both of these bioMEMS sensing devices

关键词： DNA Biosensors Molecular biophysics Probes Micromechanical devices Optical sensors Optical surface waves Optical interferometry Assembly Biomedical optical imaging

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