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XXIV World Allergy Congress 2015 Seoul, Korea. 14-17 October 2015 Abstracts

WORLD ALLERGY ORGANIZATION JOURNAL 2016年第1期9卷 1-206页

作者： [Anonymous] Korea University College of Medicine Guro Hospital Seoul South Korea College of Medicine Korea University Seoul South Korea Korea University Guro Hospital Seoul South Korea Seoul National University Boramae Hospital Seoul South Korea Division of Clinical Immunology Faculty of Medicine University of Debrecen Debrecen Hungary Meiji Pharmaceutical University Tokyo Japan Suri Medical Foundation Hospital Uttar Pradesh State India Shahid Beheshti University Tehran Iran Airlangga University Teaching Hospital Surabaya Indonesia Tokyo Metropolitan Police Hospital Tokyo Japan Shinichiro KogaSamsung Changwon Hospital Seoul South Korea Sapporo Tokushukai Hospital Sapporo Japan Department of Dermatology Yonsei University College of Medicine Seoul South Korea Brain Korea 21 PLUS Project for Medical Science Yonsei University College of Medicine Seoul South Korea Sureyyapasa Chest Diseases and Chest Surgery Training Hospital Istanbul Turkey Kangnam Sacred Heart Hospital Seoul South Korea Sakai City Medical Center Sakai Japan Osaka University Suita Japan Yonsei University College of Medicine Seoul South Korea Osaka-Minami Medical Center Kawachinagano Japan Inha University College of Medicine Incheon South Korea Inha University Hospital Incheon South Korea Center for Rhinology and Allergology Wiesbaden Wiesbaden Germany Leti Pharma Gmbh Witten Germany Postgraduate Institute of Medical Education and Research Chandigarh India West Bengal Technical University Kolkata India Institute of Microbiology Academy of Sciences of the Czech Republic Prague Czech Republic Seoul National University Hospital Seoul South Korea Ent and Allergy Centre(INDIA) Panchkula India University of Santo Tomas Hospital Manila Philippines University of Santo Tomas Faculty of Medicine Manila Philippines Kyung Hee University Hospital at Gang-Dong Seoul South Korea Sangji University Wonju South Korea Division of Allergy and Immunology Department of Internal Medicine Yonsei University Colle

A1 Pirfenidone inhibits TGF-b1-induced extracellular matrix production in nasal polyp-derived fibroblasts Jae-Min Shin, Heung-Man Lee, Il-Ho Park A2 The efficacy of a 2-week course of oral steroid in the treatment of chronic spontaneous urticaria refractory to antihistamines Hyun-Sun Yoon, Gyeong Yul Park A3 The altered distribution of follicular t helper cells may predict a more pronounced clinical course of primary sjögren’s syndrome Margit Zeher A4 Betamethasone suppresses Th2 cell development induced by langerhans cell like dendritic cells Katsuhiko Matsui, Saki Tamai, Reiko Ikeda A5 An evaluation of variousallergens in cases of allergic bronchial asthma at lucknow and neighbouring districts by intradermal skintest Drsushil Suri, Dranu Suri A6 Evaluation ferqency of ADHD in childhood asthma Marzieh Heidarzadeh Arani A7 Steven johnson syndrome caused by typhoid fever in a child Azwin Lubis, Anang Endaryanto A8 Chronic Bronchitis with Radio Contrast Media Hypersensitivity: A Case with Hypothesized GINA Step 1 Asthma Shinichiro Koga A9 The association between asthma and depression in Korean adult : An analysis of the fifth korea national health and nutrition examination survey (2010-2012) Lee Ju Suk A10 Management of allergic disease exacerbations in pregnancy Yasunobu Tsuzuki A11 Subcutaneous immunotherapy mouse model for atopic dermatitis Seo Hyeong Kim, Jung U Shin, Ji Yeon Noh, Shan Jin, Shan Jin, Hemin Lee, Jungsoo Lee, Chang Ook Park, Kwang Hoon Lee, Kwang Hoon Lee A12 Atopic disease and/or atopy are risk factors for local anesthetic allergy in patients with history of hypersensitivity reactions to drugs? Fatma Merve Tepetam A13 Food hypersensitivity in patients with atopic dermatitis in Korea Chun Wook Park, Jee Hee Son, Soo Ick Cho, Yong Se Cho, Yun Sun Byun, Yoon Seok Yang, Bo Young Chung, Hye One Kim, Hee Jin Cho A14 Anaphylaxis caused by an ant (Brachyponera chinensis) in Japan Yoshinori Katada, Toshio Tanaka, Akihiko Nakabayashi, Koji Nishida, Kenichi A

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Human genome meeting 2016 : Houston, TX, USA. 28 February - 2 March 2016

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Human genomics 2016年第1期10 Suppl 1卷 12页

作者： A. K. Srivastava Y. Wang R. Huang C. Skinner T. Thompson L. Pollard T. Wood F. Luo R. Stevenson R. Polimanti J. Gelernter X. Lin I. Y. Lim Y. Wu A. L. Teh L. Chen I. M. Aris S. E. Soh M. T. Tint J. L. MacIsaac F. Yap K. Kwek S. M. Saw M. S. Kobor M. J. Meaney K. M. Godfrey Y. S. Chong J. D. Holbrook Y. S. Lee P. D. Gluckman N. Karnani A. Kapoor D. Lee A. Chakravarti C. Maercker F. Graf M. Boutros G. Stamoulis F. Santoni P. Makrythanasis A. Letourneau M. Guipponi N. Panousis M. Garieri P. Ribaux E. Falconnet C. Borel S. E. Antonarakis S. Kumar J. Curran J. Blangero S. Chatterjee J. Akiyama D. Auer C. Berrios L. Pennacchio T. R. Donti G. Cappuccio M. Miller P. Atwal A. Kennedy A. Cardon C. Bacino L. Emrick J. Hertecant F. Baumer B. Porter M. Bainbridge P. Bonnen B. Graham R. Sutton Q. Sun S. Elsea Z. Hu P. Wang Y. Zhu J. Zhao M. Xiong David A. Bennett A. Hidalgo-Miranda S. Romero-Cordoba S. Rodriguez-Cuevas R. Rebollar-Vega E. Tagliabue M. Iorio E. D’Ippolito S. Baroni B. Kaczkowski Y. Tanaka H. Kawaji A. Sandelin R. Andersson M. Itoh T. Lassmann Y. Hayashizaki P. Carninci A. R. R. Forrest C. A. Semple E. A. Rosenthal B. Shirts L. Amendola C. Gallego M. Horike-Pyne A. Burt P. Robertson P. Beyers C. Nefcy D. Veenstra F. Hisama R. Bennett M. Dorschner D. Nickerson J. Smith K. Patterson D. Crosslin R. Nassir N. Zubair T. Harrison U. Peters G. Jarvik F. Menghi K. Inaki X. Woo P. Kumar K. Grzeda A. Malhotra H. Kim D. Ucar P. Shreckengast K. Karuturi J. Keck J. Chuang E. T. Liu B. Ji A. Tyler G. Ananda G. Carter H. Nikbakht M. Montagne M. Zeinieh A. Harutyunyan M. Mcconechy N. Jabado P. Lavigne J. Majewski J. B. Goldstein M. Overman G. Varadhachary R. Shroff R. Wolff M. Javle A. Futreal D. Fogelman L. Bravo W. Fajardo H. Gomez C. Castaneda C. Rolfo J. A. Pinto K. C. Akdemir L. Chin S. Patterson C. Statz S. Mockus S. N. Nikolaev X. I. Bonilla L. Parmentier B. King F. Bezrukov G. Kaya V. Zoete V. Seplyarskiy H. Sharpe T. McKee K. Popadin N. Basset-Seguin R. Ben Chaabene M. Andrianova C. Verdan K. Grosdemange O. Sumara M. E JCSRI Greenwood Genetic Center Greenwood USA School of Computing Clemson University Clemson USA Biochemical Genetics Laboratory Greenwood Genetic Center Greenwood USA Department Psychiatry Yale Sch Med and VA CT Healthcare Center West Haven USA Department Genetics Yale Sch Med and VA CT Healthcare Center West Haven USA Department Neurobiology Yale Sch Med and VA CT Healthcare Center West Haven USA Singapore Institute for Clinical Sciences Singapore Singapore National University of Singapore Singapore Singapore University of British Columbia Vancouver Canada KK Women’s and Children’s Hospital Singapore Singapore University of Southampton and University Hospital Southampton NHS Foundation Trust Southampton UK University of Auckland Auckland New Zealand McKusick-Nathans Institute of Genetic Medicine Johns Hopkins University School of Medicine Baltimore USA Esslingen University of Applied Sciences Esslingen Germany German Cancer Research Center Heidelberg Germany Department of Genetic Medicine and Development University of Geneva Medical School Geneva Switzerland Geneva University Hospitals-HUG Service of Genetic Medicine Geneva Switzerland GE3 Institute of Genetics and Genomics of Geneva University of Geneva Medical School Geneva Switzerland South Texas Diabetes and Obesity Institute School of Medicine University of Texas Rio-Grande Valley Edinburg USA South Texas Diabetes and Obesity Institute School of Medicine University of Texas Rio-Grande Valley Brownsville USA Institute of Genetic Medicine Johns Hopkins University Baltimore USA Genomics Division Lawrence Berkeley National Laboratory Berkeley USA Molecular and Human Genetics Baylor College of Medicine Houston USA Department of Translational Medical Sciences Federico II University Naples Italy Metabolon Inc Durham USA Section of Pediatric Neurology and Neuroscience Baylor College of Medicine Houston USA Tawam Hospital Abu Dhabi United Arab Emirates Stanford Medical School Stanford USA Sch

O1 The metabolomics approach to autism: identification of biomarkers for early detection of autism spectrum disorder A. K. Srivastava, Y. Wang, R. Huang, C. Skinner, T. Thompson, L. Pollard, T. Wood, F. Luo, R. Stevenson O2 Phenome-wide association study for smoking- and drinking-associated genes in 26,394 American women with African, Asian, European, and Hispanic descents R. Polimanti, J. Gelernter O3 Effects of prenatal environment, genotype and DNA methylation on birth weight and subsequent postnatal outcomes: findings from GUSTO, an Asian birth cohort X. Lin, I. Y. Lim, Y. Wu, A. L. Teh, L. Chen, I. M. Aris, S. E. Soh, M. T. Tint, J. L. MacIsaac, F. Yap, K. Kwek, S. M. Saw, M. S. Kobor, M. J. Meaney, K. M. Godfrey, Y. S. Chong, J. D. Holbrook, Y. S. Lee, P. D. Gluckman, N. Karnani, GUSTO study group O4 High-throughput identification of specific qt interval modulating enhancers at the SCN5A locus A. Kapoor, D. Lee, A. Chakravarti O5 Identification of extracellular matrix components inducing cancer cell migration in the supernatant of cultivated mesenchymal stem cells C. Maercker, F. Graf, M. Boutros O6 Single cell allele specific expression (ASE) IN T21 and common trisomies: a novel approach to understand DOWN syndrome and other aneuploidies G. Stamoulis, F. Santoni, P. Makrythanasis, A. Letourneau, M. Guipponi, N. Panousis, M. Garieri, P. Ribaux, E. Falconnet, C. Borel, S. E. Antonarakis O7 Role of microRNA in LCL to IPSC reprogramming S. Kumar, J. Curran, J. Blangero O8 Multiple enhancer variants disrupt gene regulatory network in Hirschsprung disease S. Chatterjee, A. Kapoor, J. Akiyama, D. Auer, C. Berrios, L. Pennacchio, A. Chakravarti O9 Metabolomic profiling for the diagnosis of neurometabolic disorders T. R. Donti, G. Cappuccio, M. Miller, P. Atwal, A. Kennedy, A. Cardon, C. Bacino, L. Emrick, J. Hertecant, F. Baumer, B. Porter, M. Bainbridge, P. Bonnen, B. Graham, R. Sutton, Q. Sun, S. Elsea O10 A novel causal methylation network approach to Alzheimer’s

关键词： Pulmonary Arterial Hypertension Oral Squamous Cell Carcinoma Deep Neural Network Autosomal Recessive Polycystic Kidney Disease Whole Genome Bisulfite Sequencing

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The global financial markets: An ultra-large-scale systems perspective

The global financial markets: An ultra-large-scale systems p...

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17th Monterey Workshop on Large-Scale Complex IT systems, LSCITS 2012

作者： Cliff, Dave Northrop, Linda UK Large Scale Complex IT System Initiative Department of Computer Science University of Bristol Bristol BS8 1UB United Kingdom Research Technology and System Solutions Program Software Engineering Institute Carnegie-Mellon University Pittsburgh PA 15213 United States

ISBN: (纸本)9783642340581

We argue here that, in recent years, the world's financial markets have become a globally interconnected complex adaptive ultra-large-scale socio-technical system-of-systems, and that this has important consequences for how the financial markets should be engineered and managed in future. Major failures in the financial markets can now occur at super-human speeds, as was witnessed in the "Flash Crash" of May 6th 2010. Events such as the Flash Crash may become more commonplace in future, unless lessons are learned from other fields where complex adaptive socio-technical systems-of-systems have to be engineered for high-integrity, safety-critical applications. In this document we review the literature on failures in risky technology and high-integrity approaches to safety-critical SoS engineering. We conclude with an argument that, in the specific case of the global financial markets, there is an urgent need to develop major national strategic modeling and predictive simulation capabilities, comparable to national-scale meteorological monitoring and modeling capabilities. The intent here is not to predict the price-movements of particular financial instruments or asset classes, but rather to provide test-rigs for principled evaluation of systemic risk, estimating probability density functions over spaces of possible outcomes, and thereby identifying potentially high-consequence failure modes in the simulations, before they occur in real life, by which time it is typically too late. © 2012 Springer-Verlag.

关键词： Information technology

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On region-based fault tolerant design of distributed file storage in networks

On region-based fault tolerant design of distributed file st...

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IEEE Annual Joint Conference: INFOCOM, IEEE computer and Communications Societies

作者： Sujogya Banerjee Shahrzad Shirazipourazad Arunabha Sen Computer Science and Engineering Program School of Computing Informatics and Decision System Engineering Arizona State University Tempe AZ USA

ISBN: (纸本)9781467307734;9781467307758

Distributed storage of data files in different nodes of a network enhances the reliability of the data by offering protection against node failure. In the (N,K),N ≥ K file distribution scheme, from a file F of size |F|, N segments of size |F|/K are created in such a way that it is possible to reconstruct the entire file, just by accessing any K segments. For the reconstruction scheme to work it is essential that the K segments of the file are stored in nodes that are connected in the network. However in case of node failures the network might become disconnected (i.e., split into several connected components). We focus on node failures that are spatially-correlated or region-based. Such failures are often encountered in disaster situations or natural calamities where only the nodes in the disaster zone are affected. The goal of this research is to devise a file segment distribution scheme so that, even if the network becomes disconnected due to any region fault, at least one of the largest connected components will have at least K distinct file segments with which to reconstruct the entire file. The distribution scheme will also ensure that the total storage requirement is minimized. We provide an optimal solution through Integer Linear programming and an approximation solution with a guaranteed performance bound of O(ln n) to solve the problem for any arbitrary network. The performance of the approximation algorithm is evaluated by simulation on two real networks.

关键词： Image color analysis Color Approximation algorithms Robustness Approximation methods Layout Encoding

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A robust gradient clock synchronization algorithm for wireless sensor networks

A robust gradient clock synchronization algorithm for wirele...

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International Communication systems and Networks and Workshops, COMSNETS

作者： André C. Pinho Daniel R. Figueiredo Felipe M. G. França System Engineering and Computer Science Program (PESC/COPPE) Federal University of Rio de Janeiro Rio de Janeiro Brazil

A variation of the classical clock synchronization problem is to synchronize clocks with an error that is proportinal to their distance in the network. Among several applications, gradient clock synchronization in wireless sensor networks can yield precise time coordination of packet transmissions, allowing for time-based collision free transmission scheduling. In this paper, we propose a simple and robust gradient clock synchronization (RGCS) algorithm designed for wireless sensor networks. The algorithm is fully distributed and operates independently of network topology, network routing and has no parameters to tune. It also does not require strict timing or reliability in clock synchronization messages or any global time reference. In particular, RGCS is based on a running average of logical clock rates and addresses specific aspects of gradient synchronization, such as estimating the logical clock of neighbors. We evaluate the algorithm through realistic simulations in various scenarios to illustrate the benefits of our approach. We also compare our results with GTSP a prominent gradient clock synchronization algorithm. Our results indicates that RCGS can operate adequately under high loss rates (50%) and high variability in the period of synchronization messages.

关键词： Synchronization Clocks Hardware Wireless sensor networks Delay Receivers Equations

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Design Pattern Usage in Grid Computing

Design Pattern Usage in Grid Computing

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International Conference on Broadband, Wireless Computing, Communication and Applications (BWCCA)

作者： Markus Aleksy Makoto Takizawa Leonard Barolli Industrial Software System Program ABB Corporate Research Center Germany Germany Department of Computer and Information Science Seikei University Tokyo Japan Department of Information and Communication Engineering Fukuoka Institute of Technology Fukuoka Japan

The recent advances in Grid and Cloud computing make new types of applications possible. At the same time, they require an infrastructure to implement heterogeneous computing resources time and cost-savely. Here, approaches that utilize design patterns, i.e., proven solutions to existing problems, seem to provide a good approach to enable these kind of applications. In this paper, we investigated which design patterns are already used in the area of Grid computing nowadays. After a brief description of the literature study design, we present our findings which include the discovered design patterns, corresponding categories, and application areas.

关键词： Grid computing Parallel processing Cloud computing Conferences Concurrent computing USA Councils

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Multiobjective optimization for project portfolio selection 12

Multiobjective optimization for project portfolio selection

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14th International Conference on Genetic and Evolutionary Computation Companion, GECCO'12 Companion

作者： De Barros, Márcio O. Costa, Hélio R. Figueiredo, Fábio V. Da Rocha, Ana Regina C. Post-graduate Information Systems Program - PPGI UNIRIO Av. Pasteur 458 Urca - Rio de Janeiro RJ Brazil COPPE UFRJ System Engineering and Computer Science Department Caixa Postal: 68511 CEP: 21945-970 - Rio de Janeiro Brazil CCA-RJ Brazilian Air Force Ponta do Galeão s/no Ilha do Governador CEP: 21941-510 - Rio de Janeiro Brazil

ISBN: (纸本)9781450311786

This paper proposes a multiobjective heuristic search approach to support a project portfolio selection technique on scenarios with a large number of candidate projects. The original formulation for the technique requires analyzing all combinations of candidate projects, which is unfeasible when more than a few alternatives are available. We have used a multiobjective genetic algorithm to partially explore the search space of project combinations and select the most effective ones. We present an experimental study based on four project selection problems that compares the results found by the genetic algorithm to those yielded by a non-systematic search procedure. Results show evidence that the project selection technique can be used in large-scale scenarios and that GA presents better results than simpler search strategy. Copyright is held by the author/owner(s).

关键词： Multiobjective optimization

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The Single Vehicle Routing Problem with Deliveries and Selective Pickups in a CPU-GPU Heterogeneous Environment

The Single Vehicle Routing Problem with Deliveries and Selec...

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IEEE International Conference on High Performance Computing and Communications (HPCC)

作者： Igor Machado Coelho Luiz Satoru Ochi Pablo Luiz Araújo Munhoz Marcone Jamilson Freitas Souza Ricardo Farias Cristiana Bentes Institute of Computing Fluminense Federal University UFF Niteroi Brazil Department of Computer Science UFOP-Federal University of Ouro Preto and FEAD Ouro Preto Brazil System Engineering Program-COPPE Federal University of Rio de Janeiro Rio de Janeiro Brazil Department of System Engineering State University of Rio de Janeiro Rio de Janeiro Brazil

In this work, we propose a new algorithm to solve a variant of the Vehicle Routing Problem that is the Single Vehicle Routing Problem with Deliveries and Selective Pickups (SVRPDSP). Our algorithm produces good quality solutions that are better than the best known solutions in the literature. In order to reduce the time spent to solve large-sized instances, we also propose here a parallel implementation of our algorithm that explores a heterogeneous environment composed of a CPU and a GPU. Therefore, our algorithm harnesses the tremendous computing power of the GPU to improve the performance of the local searches computation. We obtained average speedups from 2.73 to 16.23 times with our parallel approach.

关键词： Graphics processing unit Vehicles Parallel algorithms Vectors Resource management Optimization Routing

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Distributed real-equipment testing for the mobile communications services

Distributed real-equipment testing for the mobile communicat...

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2011 10th RoEduNet International Conference on Networking in Education and Research, RoEduNet 2011

作者： Cazacu, Virgil Iuga, Laura Balan, Titus Sandu, Florin Siemens Program and System Engineering Brasov Romania Faculty of Electrical Engineering and Computer Science Transilvania University Brasov Romania

ISBN: (纸本)9781457712333

The test activities performed during the life cycle of the telecommunication service development ensure the service quality and stability so necessary to achieve the maximum availability and reliability. The paper presents authors' contribution to remote and distributed testing for mobile communications services based on cloud computing assets and paradigms. The access solutions to the test methods were implemented for the GSM and GSM-R (Global system for Mobile - Railways) related Intelligent Networks services. The scalability and flexibility of the architecture allows to the proposed solution to be used, for both the production and the educational environments, to access the resources located on the different sites for the tests purpose. The concept of the remote test solution and the practical examples based on the remote tests with real equipments are presented in this paper. © 2011 IEEE.

关键词： Equipment testing

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Beyond connectivity-new metrics to evaluate robustness of networks

Beyond connectivity-new metrics to evaluate robustness of ne...

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International Conference on High Performance Switching and Routing

作者： Banerjee, Sujogya Shirazipourazad, Shahrzad Ghosh, Pavel Sen, Arunabha Computer Science and Engineering Program School of Computing Informatics and Decision System Engineering Arizona State University Tempe AZ 85281 United States

ISBN: (纸本)9781424484560

Robustness or fault-tolerance capability of a network is an important design parameter in both wired and wireless networks. Connectivity of a network is traditionally considered to be the primary metric for evaluation of its fault-tolerance capability. However, connectivity (G) (for random faults) or region-based connectivity R(G) (for spatially correlated or region-based faults, where the faults are confined to a region R) of a network G, does not provide any information about the network state, (i.e., whether the network is connected or not) once the number of faults exceeds (G) or R(G). If the number of faults exceeds (G) or R(G), one would like to know, (i) the number of connected components into which G decomposes, (ii) the size of the largest connected component, (iii) the size of the smallest connected component. In this paper, we introduce a set of new metrics that computes these values. We focus on one particular metric called region-based component decomposition number (RBCDN), that measures the number of connected components in which the network decomposes once all the nodes of a region fail. We study the computational complexity of finding RBCDN of a network. In addition, we study the problem of least cost design of a network with a target value of RBCDN. We show that the optimal design problem is NP-complete and present an approximation algorithm with a performance bound of O(log K + 4log n), where n denotes the number of nodes in the graph and K denotes a target value of RBCDN. We evaluate the performance of our algorithm by comparing it with the performance of the optimal solution. Experimental results demonstrate that our algorithm produces near optimal solution in a fraction of time needed to find an optimal solution. © 2011 IEEE.

关键词： Approximation algorithms

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