Hospital El Salvador: a novel paradigm of intensive care in response to COVID-19 in central America. Lancet Glob Health 2021;9: e241?42?In this Comment, the conflict of interest statement should have included the foll...
Hospital El Salvador: a novel paradigm of intensive care in response to COVID-19 in central America. Lancet Glob Health 2021;9: e241?42?In this Comment, the conflict of interest statement should have included the following: ?By virtue of their roles within a public hospital or the Ministry of Health, MB, LC, WH, and XS are government employees. The findings and conclusions in the Comment are only those of the authors.? This correction has been made as of Feb 26, 2021.
Music tracking is a useful technique for many music related tasks. Some applications include evaluating musicians performance, automatic score page turning and syncing music lyrics. In this work, we describe a WiSARD-...
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Music tracking is a useful technique for many music related tasks. Some applications include evaluating musicians performance, automatic score page turning and syncing music lyrics. In this work, we describe a WiSARD-based system for real-time music tracking and evaluate the performance of the corresponding implementation. Given any audio example, the system is capable of recognizing which point of the original signal is currently playing and of dynamically tracking it. In other words, if the music restarts or jumps to another position, the system is capable of following it. This is accomplished thanks to the low complexity training and classifying of the models used, which continually keep track of all possible points of the music, and not only of the current neighboring region. Experiments are provided in order to analyze the performance of the system in three test scenarios: tracking continuous playing, tracking multiple jumps and self predicting errors. The final results demonstrate that the system is efficient even when applied to musics with some level of repetitions and short periods of silence.
Background: The sustainable development goals (SDGs) aim to end HIV/AIDS as a public health threat by 2030. Understanding the current state of the HIV epidemic and its change over time is essential to this effort. Thi...
Background: The sustainable development goals (SDGs) aim to end HIV/AIDS as a public health threat by 2030. Understanding the current state of the HIV epidemic and its change over time is essential to this effort. This study assesses the current sex-specific HIV burden in 204 countries and territories and measures progress in the control of the epidemic. Methods: To estimate age-specific and sex-specific trends in 48 of 204 countries, we extended the Estimation and Projection Package Age-Sex Model to also implement the spectrum paediatric model. We used this model in cases where age and sex specific HIV-seroprevalence surveys and antenatal care-clinic sentinel surveillance data were available. For the remaining 156 of 204 locations, we developed a cohort-incidence bias adjustment to derive incidence as a function of cause-of-death data from vital registration systems. The incidence was input to a custom Spectrum model. To assess progress, we measured the percentage change in incident cases and deaths between 2010 and 2019 (threshold >75% decline), the ratio of incident cases to number of people living with HIV (incidence-to-prevalence ratio threshold <0·03), and the ratio of incident cases to deaths (incidence-to-mortality ratio threshold <1·0). Findings: In 2019, there were 36·8 million (95% uncertainty interval [UI] 35·1–38·9) people living with HIV worldwide. There were 0·84 males (95% UI 0·78–0·91) per female living with HIV in 2019, 0·99 male infections (0·91–1·10) for every female infection, and 1·02 male deaths (0·95–1·10) per female death. Global progress in incident cases and deaths between 2010 and 2019 was driven by sub-Saharan Africa (with a 28·52% decrease in incident cases, 95% UI 19·58–35·43, and a 39·66% decrease in deaths, 36·49–42·36). Elsewhere, the incidence remained stable or increased, whereas deaths generally decreased. In 2019, the global incidence-to-prevalence ratio was 0·05 (95% UI 0·05–0·06) and the global incidence-to-mortality ratio was
A1 Functional advantages of cell-type heterogeneity in neural circuits Tatyana O. Sharpee A2 Mesoscopic modeling of propagating waves in visual cortex Alain Destexhe A3 Dynamics and biomarkers of mental disorders Mits...
A1 Functional advantages of cell-type heterogeneity in neural circuits Tatyana O. Sharpee A2 Mesoscopic modeling of propagating waves in visual cortex Alain Destexhe A3 Dynamics and biomarkers of mental disorders Mitsuo Kawato F1 Precise recruitment of spiking output at theta frequencies requires dendritic h-channels in multi-compartment models of oriens-lacunosum/moleculare hippocampal interneurons Vladislav Sekulić, Frances K. Skinner F2 Kernel methods in reconstruction of current sources from extracellular potentials for single cells and the whole brains Daniel K. Wójcik, Chaitanya Chintaluri, Dorottya Cserpán, Zoltán Somogyvári F3 The synchronized periods depend on intracellular transcriptional repression mechanisms in circadian clocks. Jae Kyoung Kim, Zachary P. Kilpatrick, Matthew R. Bennett, Kresimir Josić O1 Assessing irregularity and coordination of spiking-bursting rhythms in central pattern generators Irene Elices, David Arroyo, Rafael Levi, Francisco B. Rodriguez, Pablo Varona O2 Regulation of top-down processing by cortically-projecting parvalbumin positive neurons in basal forebrain Eunjin Hwang, Bowon Kim, Hio-Been Han, Tae Kim, James T. McKenna, Ritchie E. Brown, Robert W. McCarley, Jee Hyun Choi O3 Modeling auditory stream segregation, build-up and bistability James Rankin, Pamela Osborn Popp, John Rinzel O4 Strong competition between tonotopic neural ensembles explains pitch-related dynamics of auditory cortex evoked fields Alejandro Tabas, André Rupp, Emili Balaguer-Ballester O5 A simple model of retinal response to multi-electrode stimulation Matias I. Maturana, David B. Grayden, Shaun L. Cloherty, Tatiana Kameneva, Michael R. Ibbotson, Hamish Meffin O6 Noise correlations in V4 area correlate with behavioral performance in visual discrimination task Veronika Koren, Timm Lochmann, Valentin Dragoi, Klaus Obermayer O7 Input-location dependent gain modulation in cerebellar nucleus neurons Maria Psarrou, Maria Schilstra, Neil Davey, Benjamin Torben-Ni
An Orthogonal Frequency Division Multiplexing (OFDM) scheme is expected as an efficient technique for next generation wireless communications. However, high Peak to Average Power Ration (PAPR) of OFDM system is the ma...
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An Orthogonal Frequency Division Multiplexing (OFDM) scheme is expected as an efficient technique for next generation wireless communications. However, high Peak to Average Power Ration (PAPR) of OFDM system is the main drawback which degrades the transmitter power efficiency causes poor performance of the system. To reduce PAPR of OFDM signal, several works on clipping technique have been proposed. This paper is incorporated the improvement of the PAPR and Bit Error Rate (BER) performance using clipping method. It has been shown from the result that by employing the recursive clipping and filtering, 11.45 dB of PAPR of original OFDM signal is reduced down to 4.77 dB. Hence, BER is also increased significantly. This research is carried out through MATLAB simulation and gradually measured the effect of PAPR on BER under AWGN channel for 16QAM scheme with 256 points OFDM. Moreover, it is studied the effect of OFDM signal while passing through High Power Amplifier (HPA). Finally, the PAPR reduction technique such as recursive clipping and filtering (RCF) is implemented.
The critical infrastructures of a nation including the power grid and the communication network are highly interdependent. Recognizing the need for a deeper understanding of the interdependency in a multi-layered netw...
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Software development comprises the execution of a variety of tasks, such as bug discovery, finding reusable assets, dependency analysis etc. A better understanding of the task at hand and its surroundings can improve ...
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The software industry has evolved to a multiple-product development created on a platform and based on a common architecture integrated to other systems. This integration happens through components and third-party dev...
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The software industry has evolved to a multiple-product development created on a platform and based on a common architecture integrated to other systems. This integration happens through components and third-party developers networks in Software Ecosystems (SECOs). Since systems and software development processes present challenges beyond the technical side, SECOs have emerged as an approach to improve the Software engineering (SE) mindset in the industry. This fact changes the software industry as it requires the management of an integrated social-based environment to support a transition from an intra-organizational to an open business model approach towards a SECO approach. In this context, social networks can be important to coordinate a collaborative and distributed environment to develop SECOs platforms. This paper analyses the impact of social networks in SECOs through an integrated framework of the SECO and social network challenges. So, a proposal for a sociotechnical-based architecture to support the SECOs lifecycle is discussed.
Transcriptomic imputation approaches combine eQTL reference panels with large-scale genotype data in order to test associations between disease and gene expression. These genic associations could elucidate signals in ...
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Transcriptomic imputation approaches combine eQTL reference panels with large-scale genotype data in order to test associations between disease and gene expression. These genic associations could elucidate signals in complex genome-wide association study (GWAS) loci and may disentangle the role of different tissues in disease development. We used the largest eQTL reference panel for the dorso-lateral prefrontal cortex (DLPFC) to create a set of gene expression predictors and demonstrate their utility. We applied DLPFC and 12 GTEx-brain predictors to 40,299 schizophrenia cases and 65,264 matched controls for a large transcriptomic imputation study of schizophrenia. We identified 413 genic associations across 13 brain regions. Stepwise conditioning identified 67 non-MHC genes, of which 14 did not fall within previous GWAS loci. We identified 36 significantly enriched pathways, including hexosaminidase-A deficiency, and multiple porphyric disorder pathways. We investigated developmental expression patterns among the 67 non-MHC genes and identified specific groups of pre- and postnatal expression.
Given a set of underwater sensors coordinates that are usually determined by a specialist for the design of a watershed monitoring system, where should be placed the sinks and the base station? The answer may be the m...
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ISBN:
(纸本)9781450332774
Given a set of underwater sensors coordinates that are usually determined by a specialist for the design of a watershed monitoring system, where should be placed the sinks and the base station? The answer may be the minimization of the Variable Internode Distance. In such cases, a two dimensional architecture is acceptable because it is a shallow water system. Hence, in this paper, it is proposed a two-level node distance minimization for Underwater Wireless Sensor Network for monitoring systems. The mathematical method employed for optimization is the Hyperbolic Smoothing approach and the proposed method includes the placement of the base-station in the algorithm. Copyright 2014 ACM.
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