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Non-invasive biopsy diagnosis of diabetic kidney disease via deep learning applied to retinal images: a population-based study

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The Lancet Digital Health 2025年第5期7卷 100868页

作者： Meng, Ziyao Guan, Zhouyu Yu, Shujie Wu, Yilan Zhao, Yaoning Shen, Jie Lim, Cynthia Ciwei Chen, Tingli Yang, Dawei Ran, An Ran He, Feng Hamzah, Haslina Singh, Sarkaaj Abd Raof, Anis Syazwani Lee-Boey, Jian Wen Samuel Lim, Soo-Kun Sun, Xufang Ge, Shuwang Xu, Gang Su, Hua Cheng, Yang Lu, Feng Liao, Xiaofei Jin, Hai Deng, Chenxin Ruan, Lei Zhang, Cuntai Wu, Chan Dai, Rongping Jin, Yixiao Wang, Wenxiao Li, Tingyao Liu, Ruhan Li, Jiajia Shu, Jia Lu, Yuwei Wang, Xiangning Wu, Qiang Qin, Yiming Tang, Jin Sheng, Xiaohua Jiao, Qiong Yang, Xiaokang Guo, Minyi McKay, Gareth J Hogg, Ruth E Liew, Gerald Chee, Evelyn Yi Lyn Hsu, Wynne Lee, Mong Li Szeto, Simon Luk, Andrea O Y Chan, Juliana C N Cheung, Carol Y Tan, Gavin Siew Wei Tham, Yih-Chung Cheng, Ching-Yu Sabanayagam, Charumathi Lim, Lee-Ling Jia, Weiping Li, Huating Sheng, Bin Wong, Tien Yin Shanghai Belt and Road International Joint Laboratory of Intelligent Prevention and Treatment for Metabolic Diseases Department of Computer Science and Engineering School of Electronic Information and Electrical Engineering Institute for Proactive Healthcare Shanghai Jiao Tong University Department of Endocrinology and Metabolism Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine Shanghai Diabetes Institute Shanghai Clinical Centre for Diabetes Shanghai Key Laboratory of Diabetes Mellitus Shanghai China MOE Key Laboratory of AI School of Electronic Information and Electrical Engineering Shanghai Jiao Tong University Shanghai China Beijing Tsinghua Changgung Hospital Eye Center School of Clinical Medicine Tsinghua Medicine Tsinghua University Beijing China Medical Records and Statistics Office Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine Shanghai China Department of Renal Medicine Singapore General Hospital SingHealth-Duke Academic Medical Centre Singapore Singapore Department of Ophthalmology Shanghai Health and Medical Center Wuxi China Department of Ophthalmology and Visual Sciences The Chinese University of Hong Kong Hong Kong Special Administrative Region China Singapore Eye Research Institute Singapore National Eye Centre Singapore Department of Medicine Faculty of Medicine Universiti Malaya Kuala Lumpur Malaysia Department of Ophthalmology Tongji Hospital Tongji Medical College Huazhong University of Science and Technology Hubei Wuhan China Department of Nephrology Tongji Hospital Tongji Medical College Huazhong University of Science and Technology Wuhan China Department of Nephrology Union Hospital Tongji Medical College Huazhong University of Science and Technology Wuhan China Department of Ophthalmology Union Hospital Tongji Medical College Huazhong University of Science and Technology Wuhan China National Engineering Research Centre for Big Dat

Background: Improving the accessibility of screening diabetic kidney disease (DKD) and differentiating isolated diabetic nephropathy from non-diabetic kidney disease (NDKD) are two major challenges in the field of diabetes care. We aimed to develop and validate an artificial intelligence (AI) deep learning system to detect DKD and isolated diabetic nephropathy from retinal fundus images. Methods: In this population-based study, we developed a retinal image-based AI-deep learning system, DeepDKD, pretrained using 734 084 retinal fundus images. First, for DKD detection, we used 486 312 retinal images from 121 578 participants in the Shanghai Integrated Diabetes Prevention and Care system for development and internal validation, and ten multi-ethnic datasets from China, Singapore, Malaysia, Australia, and the UK (65 406 participants) for external validation. Second, to differentiate isolated diabetic nephropathy from NDKD, we used 1068 retinal images from 267 participants for development and internal validation, and three multi-ethnic datasets from China, Malaysia, and the UK (244 participants) for external validation. Finally, we conducted two proof-of-concept studies: a prospective real-world study with 3 months' follow-up to evaluate the effectiveness of DeepDKD in screening DKD;and a longitudinal analysis of the effectiveness of DeepDKD in differentiating isolated diabetic nephropathy from NDKD on renal function changes with 4·6 years' follow-up. Findings: For detecting DKD, DeepDKD achieved an area under the receiver operating characteristic curve (AUC) of 0·842 (95% CI 0·838–0·846) on the internal validation dataset and AUCs of 0·791–0·826 across external validation datasets. For differentiating isolated diabetic nephropathy from NDKD, DeepDKD achieved an AUC of 0·906 (0·825–0·966) on the internal validation dataset and AUCs of 0·733–0·844 across external validation datasets. In the prospective study, compared with the metadata model, DeepDKD could detect DKD wit

关键词： Deep learning

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Investigation of thermal properties of ethylene glycol-based Williamson hybrid-nanofluid over stretchable/shrinking flat plate and their effects on solar panels

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International Journal of Thermofluids 2024年 24卷

作者： Aselebe, L.O. Adeosun, A.T. Kasali, K.B. Yisa, B.M. Salaudeen, K.A. Adesina, R.O. Federal School of Surveying Oyo Nigeria Department of Mathematics Federal College of Education Iwo Nigeria Department of Mathematics and Statistics First Technical University Ibadan Nigeria Department of Mathematics Faculty of Physical Sciences University of Ilorin Ilorin Nigeria Department of Mathematics and Computing Science Education Faculty of Science Education Emmanuel Alayande University of Education Oyo Nigeria Energy System Science and Engineering Program Department of Electronic and Electrical Engineering Obafemi Awolowo University Ile-Ife Nigeria

The global requirement for sustainable energy supply to enhance industrial productivity and reduce production costs has focused researchers’ attention to renewable energy in recent years. Solar energy mitigates the dangers connected with the use of fossil fuels in electricity generation. This work is set to evaluate the heat transmission capacities of Williamson hybrid nanofluid flow across a flat plate with viscous dissipation and heat source. The mathematical model explaining the flow interaction of Williamson hybrid nanofluid, combining viscous dissipation, heat source, and temperature-variation thermal conductivity and viscosity, is created using conservation laws. The specified system of non-linear coupled partial differential equations undergoes non-similarity transformation. The resulting non-dimensional model is solved using the bivariate spectral weighted residual method. The accuracy of the method is proven by comparing obtained results with those in the literature, and a good agreement is observed. Graphs are utilized to explain the thermophysical properties that are being considered. The results show that the fluid temperature rises when there is a source of heating and viscous dissipation. The velocity and the fluid parameter (We) have an inverse connection, whereas the temperature of the fluid has the opposite impact. Moreover, when nanoparticles are present, the thermal boundary layer rises along with the nanoparticles, thickening the velocity boundary layer and decreasing fluid velocity. Findings also show that for the Vd∈[0.1,0.5], the skin drag force and Nusselt number retard by 0.64%,14.06% for the shrinking sheet and 0.21%,6.57% for the stretching sheet respectively. In the same vein, an 100% surge in the porosity parameter escalate the skin friction coefficient by 19.13% and 26.91% and the Nusselt number by 4.92% and 2.06% respectively for both the contracting and elastic sheet. The findings in the research will provide more insight in the desig

关键词： Nusselt number

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Intrinsic Parameter Fluctuation and Process Variation Effect of Vertically Stacked Silicon Nanosheet Complementary Field-Effect Transistors

Intrinsic Parameter Fluctuation and Process Variation Effect...

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IEEE International Symposium on Quality Electronic Design

作者： Sekhar Reddy Kola Yiming Li Min-Hui Chuang Parallel and Scientific Computing Laboratory Hsinchu Taiwan Electrical Engineering and Computer Science International Graduate Program Hsinchu Taiwan Institute of Communications Engineering Hsinchu Taiwan Institute of Biomedical Engineering Hsinchu Taiwan Institute of Pioneer Semiconductor Innovation Hsinchu Taiwan Institute of Artificial Intelligence Innovation Hsinchu Taiwan Department of Electronics and Electrical Engineering National Yang Ming Chiao Tung University Hsinchu Taiwan Center for mmWave Smart Radar System and Technologies National Yang Ming Chiao Tung University Hsinchu Taiwan

We study the variability of vertically stacked gate-all-around silicon nanosheet (GAA Si NS) complementary field-effect transistors (CFETs). The process variation effect (PVE), the work function fluctuation (WKF), and the random dopant fluctuation (RDF) of CFETs are statistically estimated using an experimentally validated device simulation technique. Among five factors of PVE, the channel thickness (T Nch /T Pch ), the channel width (W ch ), and the gate length (L G ) are significant. Owing to superior GAA channel control and increased effective gate area, both WKF and RDF are suppressed. Notably, the PVE on both N-/P-FETs of GAA Si CFET induce the largest off-state current fluctuations of 80% and 278%, respectively, because the device characteristic is very sensitive to the layer thickness and width of channel.

关键词： Fluctuations Gallium arsenide Logic gates Electric variables Silicon Resource description framework Semiconductor process modeling

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Zema Dataset: A Comprehensive Study of Yaredawi Zema with a Focus on Horologium Chants

arXiv

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arXiv 2024年

作者： Muluneh, Mequanent Argaw Peng, Yan-Tsung Degife, Worku Abebe Tadesse, Nigussie Abate Demeku, Aknachew Mebreku Su, Li Institute of Information Science Academia Sinica Taipei Taiwan Department of Information System University of Gondar Gondar Ethiopia Department of Computer Science National Chengchi University Taipei Taiwan Social Networks and Human-Centered Computing Program Taiwan International Graduate Program Taiwan Department of Information Management National Taiwan University of Science and Technology Taipei Taiwan Department of Material Science and Engineering National Taiwan University of Science and Technology Taipei Taiwan

Computational music research plays a critical role in advancing music production, distribution, and understanding across various musical styles in the world. Despite the immense cultural and religious significance, the Ethiopian Orthodox Tewahedo Church (EOTC) chants are relatively underrepresented in computational music research. This paper contributes to this field by introducing a new dataset specifically tailored for the analysis of EOTC chants, also known as Yaredawi Zema. This work provides a comprehensive overview of a 10-hour dataset, 369 instances, creation, and curation process, including rigorous quality assurance measures. Our dataset has a detailed word-level temporal boundary and reading tone annotation along with the corresponding chanting mode label of audios. Moreover, we have also identified the chanting options associated with multiple chanting notations in the manuscript by annotating them accordingly. Our goal in making this dataset available to the public1 is to encourage more research and study of EOTC chants, including lyrics transcription, lyric-to-audio alignment, and music generation tasks. Such research work will advance knowledge and efforts to preserve this distinctive liturgical music, a priceless cultural artifact for the Ethiopian people. © 2024, CC BY.

关键词： Music

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Preprocessing Techniques for Enhancing Vision-Based Detection system for Tire Sidewall Extraction

Preprocessing Techniques for Enhancing Vision-Based Detectio...

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International Seminar on Research of Information Technology and Intelligent systems (ISRITI)

作者： Jia Hao Loo Veronica Lestari Jauw Chin Seong Lim Khairul-Rijal Sarmin Nunung Nurul Qomariyah Ahmad Nurul Fajar Department of Mechanical Materials and Manufacturing Engineering University of Nottingham Malaysia Malaysia Continental Tyre Technology Centre Malaysia Petaling Jaya Malaysia Computer Science Department School of Computing and Creative Arts Bina Nusantara University Jakarta Indonesia Information System Management Department BINUS Graduate Program-Master Information Systems Bina Nusantara University Jakarta Indonesia

ISBN: (数字)9798331519643

ISBN: (纸本)9798331519650

This study aims to develop a system for extracting crucial information from tire sidewalls using Optical Character Recognition (OCR). Initially, images of tire were captured manually by smartphone cameras, including Redmi 9T, iPhone 11, and Galaxy S23 Ultra. The captured images are then transferred to a computer for storage. Subsequently, these images were cropped according to the boundaries identified by Hough Circle Transform (HCT). The cropped images were then further pre-processed. During the pre-processing phase, geometrical transformation and image sharpening techniques are applied to enhance the clarity and readability of the text images. The text is then extracted using Google Vision, with the extracted text categorized by size, DOT, brand and pattern. The results indicated that the effectiveness of image pre-processing was constrained by the accuracy of circle detection, which reached a maximum rate of 87.1%. This causes parts of the text to be cut out inaccurately, leading to a suboptimal extraction accuracy of 55.65%. It is also observed that the Redmi 9T camera produced inconsistent results compared to other devices. Specifically, the iPhone 11 and Samsung Galaxy S23 Ultra demonstrated superior extraction accuracies of 69.71% and 66.37%, respectively, whereas the Redmi 9T achieved a lower extraction accuracy of 37.76%.

关键词： Accuracy Optical character recognition Text categorization Lighting Transforms US Department of Transportation Cameras Tires Internet Data mining

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One Day Smart Grid Supersession - Analytics and Integration

One Day Smart Grid Supersession - Analytics and Integration

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General Meeting of the IEEE-Power-and-Energy-Society (PES)

作者： Liu, W-H Edwin McArthur, Stephen Giri, Jay Miu, Karen Pratt, Rob Wen, Jun Uluski, Bob Dow, Luther Labut, Gerard IEEE Computing and Analytical Methods Subcommittee United States IEEE PES Intelligent Systems Subcommittee United States IEEE PES Multi-Agent System Working Group United States Power Systems Technology and Strategic Initiatives ALSTOM Grid Redmond WA United States Electrical and Computer Engineering Department Drexel University United States Pacific Northwest National Laboratory's (PNNL's) Smart Grid R and D Program U.S. Department of Energy United States Transmission and Interconnection Planning Group Southern California Edison (SCE) Company United States WECC Modeling and Validation Working Group United States EPRI Power Delivery and Utilization Area United States Distribution and West Coast Operations Quanta Technology United States Distribution Operations SmartCurrentssm Program Strategy DTE Energy Detroit MI United States

ISBN: (纸本)9781457710018

The effort of "Smart Grid" is to modernize grid infrastructure and build-in intelligence to power grids and delivery systems, and their interfaces to customer premises. However, the perspectives range from an emphasis on infrastructure to an emphasis on new paradigm-shifting applications. Alternatively, the smart grid can be thought of as the advanced information technologies that enable the desired analytical applications. As a general understanding, we believe that Smart Grid needs to integrate power system analysis, computing and economics to enhance grid reliability, efficiency, and security, and contributes to the climate change strategic goal. In this Supersession, the analytics that empowers smart grid applications is discussed;and the practical implementation and integration challenges will be presented.

关键词： smart grid analytical applications system integration

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Application of Deep Artificial Neural Network to Model Characteristic Fluctuation of Multi-Channel Gate-All-Around Silicon Nanosheet and Nanofin MOSFETs Induced by Random Nanosized Metal Grains

Application of Deep Artificial Neural Network to Model Chara...

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IEEE Electron Devices Technology and Manufacturing Conference (EDTM)

作者： Sagarika Dash Yiming Li Wen-Li Sung Parallel and Scientific Computing Laboratory National Yang-Ming Chiao Tung University Hsinchu Taiwan Electrical Engineering and Computer Science International Graduate Program National Yang-Ming Chiao Tung University Hsinchu Taiwan Institute of Communications Engineering National Yang-Ming Chiao Tung University Hsinchu Taiwan Department of Electronics and Electrical Engineering National Yang-Ming Chiao Tung University Hsinchu Taiwan Institute of Biomedical Engineering National Yang-Ming Chiao Tung University Hsinchu Taiwan Center for mm Wave Smart Radar System and Technologies National Yang-Ming Chiao Tung University Hsinchu Taiwan

In this work, we propose a deep artificial neural network (D-ANN) to estimate the work function fluctuation (WKF) on 4-channel stacked gate-all-around (GAA) silicon (Si) nanosheet (NS) and nanofin (NF) MOSFET devices for the first time. The 2-layered simple deep model can well predict the transfer characteristics for both NS/NF FET with a large number of (128) input features, utilizing considerably lesser (1100 samples) data uniformly. The resultant model is evaluated by the $\mathrm{R}^{2}$ score and RMSE to witness its competency and the average error is $< 4\%$ . We do also discuss the circuit simulation possibility by applying the ANN approach.

关键词： Semiconductor device modeling MOSFET Gallium arsenide Artificial neural networks Predictive models Logic gates Silicon

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A deep learning system for predicting time to progression of diabetic retinopathy

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NATURE MEDICINE 2024年第2期30卷 358-359页

作者： [Anonymous] Shanghai Belt and Road International Joint Laboratory for Intelligent Prevention and Treatment of Metabolic Disorders Department of Computer Science and Engineering School of Electronic Information and Electrical Engineering Shanghai Jiao Tong University Department of Endocrinology and Metabolism Shanghai Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine Shanghai Diabetes Institute Shanghai Clinical Center for Diabetes Shanghai China MOE Key Laboratory of AI School of Electronic Information and Electrical Engineering Shanghai Jiao Tong University Shanghai China Department of Ophthalmology Huadong Sanatorium Wuxi China Department of Ophthalmology Shanghai Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine Shanghai China Department of Ophthalmology and Visual Sciences The Chinese University of Hong Kong Hong Kong China Singapore Eye Research Institute Singapore National Eye Centre Singapore Singapore Department of Computer Science and Engineering The Hong Kong University of Science and Technology Hong Kong China Department of Chemical and Biological Engineering The Hong Kong University of Science and Technology Hong Kong China State Key Laboratory of Ophthalmology Zhongshan Ophthalmic Center Sun Yat-sen University Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science Guangzhou China Department of Ophthalmology Peking Union Medical College Hospital Peking Union Medical College Chinese Academy of Medical Sciences Beijing China Medical Records and Statistics Office Shanghai Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine Shanghai China Department of Geriatrics Tongji Hospital Tongji Medical College Huazhong University of Science and Technology Wuhan China National Engineering Research Center for Big Data Technology and System Services Computing Technology and System Lab Cluster and Grid Computing Lab School of Computer Science and Tech

We developed and validated a deep learning system (termed DeepDR Plus) in a diverse, multiethnic, multi-country dataset to predict personalized risk and time to progression of diabetic retinopathy. We show that DeepDR Plus can be integrated into the clinical workflow to promote individualized intervention strategies for the management of diabetic retinopathy.

关键词： Diabetes complications Machine learning Predictive markers

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Dynamic Digital Signage system: A Cost-Effective and Unified Web-Based Solution for Content and Analytics Management

Dynamic Digital Signage System: A Cost-Effective and Unified...

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Image Processing and Media computing (ICIPMC), International Conference on

作者： Kriselyn Cabading Orlando Malaca Ronaldo Juanatas Policarpio Tena Joselito Eduard Goh Marie Luvett Goh Irish Juanatas Roben Juanatas College of Engineering Technological University of the Philippines Manila Philippines College of Industrial Education Technological University of the Philippines Manila Philippines Graduate Program and External Studies Technological University of the Philippines Manila Philippines College of Information System De La Salle – College of Saint Benilde Manila Philippines IT Department College of Computer Studies and Multimedia Arts Far Eastern University – Institute of Technology Manila Philippines Information Technology Department Far Eastern University Quezon City Philippines College of Computing and Information Technology National University Philippines Manila Philippines

While several content management systems (CMS) and audience analytics tools are available for digital signage in the market, they are often sold separately and can be expensive. Therefore, this project aims to design a cost-effective and unified web-based solution for digital signage that combines content management and audience analytics functions, reducing the need for multiple purchases. This can be achieved by utilizing Raspberry Pi technology, known for its cost-effectiveness and versatility in integrations, along with a face recognition camera and machine learning methods. This proof of concept demonstrates the integration of these components to create a dynamic digital signage system. Overall, this project has the potential to offer an affordable solution for companies aiming to efficiently manage and optimize their digital marketing strategies, especially in the Digital Out-of-Home (DOOH) Advertising space.

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Scaling Limitations of Line TFETs at Sub-8-nm Technology Node

Scaling Limitations of Line TFETs at Sub-8-nm Technology Nod...

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International Symposium on VLSI Technology, systems and Applications

作者： Narasimhulu Thoti Yiming Li Sekhar Reddy Kola Parallel and Scientific Computing Laboratory National Chiao Tung University 1001 Ta-Hsueh Rd. Hsinchu Taiwan EECS International Graduate Program National Chiao Tung University 1001 Ta-Hsueh Rd. Hsinchu Taiwan Institute of Communications Engineering National Chiao Tung University 1001 Ta-Hsueh Rd. Hsinchu Taiwan Department of Electrical and Computer Engineering National Chiao Tung University 1001 Ta-Hsueh Rd. Hsinchu Taiwan Center for mmWave Smart Radar System and Technologies National Chiao Tung University 1001 Ta-Hsueh Rd. Hsinchu Taiwan

ISBN: (数字)9781728142326

ISBN: (纸本)9781728142333

The scope of the work is to investigate limitations in device scaling by identifying various parameters of short channel effects (SCEs) in current challenging geometries of the line tunnel field effect transistors (TFETs). Key factors of the considered device, such as the doping and the thickness (t n ) of n-epitaxial region, and source-to-drain length (L SDeff ) scaling cannot be tuned anymore to boost the device characteristics for the sub-8-nm technology node. The main results of this study indicates that the engineering acceptable performance are achieved at a low doping of 5 × 10 18 cm -3 , an optimal t n as low (about 0.5 nm), and a L SDeff greater than 12.5 nm. Hence, the line TFETs below sub-8-nm faces serious bottleneck of scaling and cannot be further scaled with the conventional scaling rule at all.

关键词： Electron devices Solids

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