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2024 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2024

作者： Zhang, Jun Yan, Zhiqiang Zeng, Hao Zhu, Zexuan Shenzhen University National Engineering Laboratory for Big Data System Computing Technology Shenzhen China Shenzhen University College of Computer Science and Software Engineering Shenzhen China

ISBN: (纸本)9798350386226

Aptamers are single-stranded DNA or RNA oligonucleotides that selectively bind to specific targets, making them valuable for drug design and diagnostic applications. Identifying the interactions between aptamers and target proteins is crucial for these applications. The systematic evolution of ligands by exponential enrichment process, traditionally used for this purpose, is challenging and time-consuming. The resulting aptamers often suffer from limitations in stability and diversity. Computational approaches have shown promise in aiding the discovery of high-performance aptamers, but existing methods are usually constrained by insufficient training data and limited generalizability. Recently, advancements in pre-training large language models have offered a new avenue to mitigate the dependency on large datasets. In this study, we propose a novel method to predict aptamer-protein interactions using large language models within a contrastive learning framework. Experimental results demonstrate that our method exhibits superior generalization and outperforms existing approaches. This method holds promise as a powerful tool for predicting aptamer-protein interactions. © 2024 IEEE.

关键词： Contrastive Learning

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Towards optimized tensor code generation for deep learning on sunway many-core processor

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Frontiers of Computer Science 2024年第2期18卷 1-15页

作者： Mingzhen LI Changxi LIU Jianjin LIAO Xuegui ZHENG Hailong YANG Rujun SUN Jun XU Lin GAN Guangwen YANG Zhongzhi LUAN Depei QIAN State Key Laboratory of Software Development Environment Beijing 100191China School of Computer Science and Engineering Beihang UniversityBeijing 100191China National University of Singapore Singapore 119077Singapore State Key Laboratory of Mathematical Engineering and Advanced Computing Wuxi 214000China Science and Technology on Special System Simulation Laboratory Beijing Simulation Center Beijing 100854China Department of Computer Science and Technology Tsinghua UniversityBeijing 100084China

The flourish of deep learning frameworks and hardware platforms has been demanding an efficient compiler that can shield the diversity in both software and hardware in order to provide application *** the existing deep learning compilers,TVM is well known for its efficiency in code generation and optimization across diverse hardware *** the meanwhile,the Sunway many-core processor renders itself as a competitive candidate for its attractive computational power in both scientific computing and deep learning *** paper combines the trends in these two ***,we propose swTVM that extends the original TVM to support ahead-of-time compilation for architecture requiring cross-compilation such as *** addition,we leverage the architecture features during the compilation such as core group for massive parallelism,DMA for high bandwidth memory transfer and local device memory for data locality,in order to generate efficient codes for deep learning workloads on *** experiment results show that the codes generated by swTVM achieve 1.79x improvement of inference latency on average compared to the state-of-the-art deep learning framework on Sunway,across eight representative *** work is the first attempt from the compiler perspective to bridge the gap of deep learning and Sunway processor particularly with productivity and efficiency in *** believe this work will encourage more people to embrace the power of deep learning and Sunwaymany-coreprocessor.

关键词： sunway processor deep learning compiler code generation performance optimization

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3DGCformer: 3-Dimensional Graph Convolutional transformer for multi-step origin–destination matrix forecasting

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Applied Intelligence 2025年第6期55卷 1-18页

作者： Huang, Yiou Deng, Hao Zhao, Shengjie School of Computer Science and Technology Tongji University Shanghai China Key Laboratory of Embedded System and Service Computing Shanghai China Engineering Research Center of Key Software Technologies for Smart City Perception and Planning Ministry of Education Shanghai China

Forecasting Human mobility is of great significance in the simulation and control of infectious diseases like COVID-19. To get a clear picture of potential future outbreaks, it is necessary to forecast multi-step Origin–Destination (OD) matrices for a relatively long period in the future. However, multi-step Origin–Destination Matrix Forecasting (ODMF) is a non-trivial problem. First, previous ODMF models only forecast the OD matrix for the next time-step, and they cannot perform well on long-term multi-step forecasts due to error accumulation. Second, many ODMF methods capture spatial and temporal dependencies with separate modules, which is insufficient to model spatio-temporal correlations in the time-varying OD matrix sequence. To address the challenges in multi-step ODMF, we propose 3-Dimensional Graph Convolutional Transformer (3DGCformer). As an enhancement of the original 3DGCN, we propose a novel Origin–Destination Feature Propagation (ODFP) rule between 3DGCN layers and integrate 2 3DGCNs with different spatio-temporal graphs and corresponding feature propagation rules to model the formation of OD flows in a more comprehensive way. For multi-step forecasts, 3DGCformer uses Transformer to capture long-term global temporal dependency, and adapt its decoder using labeled tokens to avoid error accumulation and improve time efficiency. To avoid information loss as the number of regions increases, we propose a patch embedding approach to convert data from 3DGCNs to the Transformer module. We perform extensive experiments on 4 real-world human mobility datasets, and the results show that our proposed model outperforms the state-of-the-art methods. © The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2025.

关键词： Convolution

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Active Deduction Heuristic Algorithm of Standard Contradiction Separation Rule Based on Reinforcement Learning 18

Active Deduction Heuristic Algorithm of Standard Contradicti...

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18th International Conference on Intelligent systems and Knowledge engineering, ISKE 2023

作者： Zhong, Jian Liu, Peiyao Chen, Shuwei School of Computer and Software Engineering National-Local Joint Engineering Laboratory of System Credibility Automatic Verification Xihua University Chengdu China

ISBN: (纸本)9798350318401

Machine learning has been a prominent research focus in recent years, and integrating machine learning methods into automated theorem provers has become a current trend in theorem proving research. Standard contradiction separation rule is a newly proposed multi-clause, dynamic, and synergized deductive inference rule. The key aspect of standard contradiction separation rule is how to plan deduction paths. In order to better plan the deduction path, this paper explores the dynamic learning within the process of contradiction separation deduction and introduces a novel active deductive heuristic algorithm based on reinforcement learning. Experimental results demonstrate that this new algorithm enhances the reasoning capability of the theorem prover Prover9. © 2023 IEEE.

关键词： Reinforcement learning

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Massively parallel algorithms for fully dynamic all-pairs shortest paths

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Frontiers of Computer Science 2024年第4期18卷 201-203页

作者： Chilei WANG Qiang-Sheng HUA Hai JIN Chaodong ZHENG National Engineering Research Center for Big Data Technology and System Services Computing Technology and System LabCluster and Grid Computing LabSchool of Computer Science and TechnologyHuazhong University of Science and TechnologyWuhan 430074China State Key Laboratory for Novel Software Technology Nanjing UniversityNanjing 210023China

1 Introduction In recent years,the Massively Parallel Computation(MPC)model has gained significant ***,most of distributed and parallel graph algorithms in the MPC model are designed for static graphs[1].In fact,the graphs in the real world are constantly *** size of the real-time changes in these graphs is smaller and more *** graph algorithms[2,3]can deal with graph changes more efficiently[4]than the corresponding static graph ***,most studies on dynamic graph algorithms are limited to the single machine ***,a few parallel dynamic graph algorithms(such as the graph connectivity)in the MPC model[5]have been proposed and shown superiority over their parallel static counterparts.

关键词： dynamic shortest gained

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A novel policy iteration algorithm for solving the optimal consensus control problem of a discrete-time multiagent system with unknown dynamics

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Science China(Information Sciences) 2023年第8期66卷 269-270页

作者： Wenkai XU Li WANG Shiwen SUN Chengyi XIA Zengqiang CHEN Tianjin Key Laboratory of Intelligence Computing and Novel Software Technology Tianjin University of Technology The Engineering Research Center of Learning-Based Intelligent System Ministry of Education College of Artificial Intelligence Nankai University

At present, an increasing number of researchers have noticed the importance of optimal consensus control(OCC) of multiagent systems(MASs) because of their rich practical applications in various areas [1–4]. To accomp...

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Multi-Stage Transfer Learning Evolutionary Algorithm for Dynamic Multiobjective Optimization 13

Multi-Stage Transfer Learning Evolutionary Algorithm for Dyn...

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13th IEEE Congress on Evolutionary Computation, CEC 2024

作者： Wang, Qianhui Zhu, Qingling Ji, Junkai College of Computer Science and Software Engineering Shenzhen University Shenzhen China Shenzhen University National Engineering Laboratory for Big Data System Computing Technology Shenzhen518060 China

ISBN: (纸本)9798350308365

Recently, the application of transfer learning within dynamic multiobjective evolutionary algorithms (DMOEAs) has shown significant potential to solve dynamic multiobjective optimization problems (DMOPs). This approach utilizes the transfer learning technique which reuses information from previous environments to accelerate the search process in the new environment. However, the risk of negative transfer can lead to an erroneous search direction and inefficient use of computational resources. To address this issue, this paper proposes a novel multistage transfer learning DMOEA, named MSTL. The algorithm is designed to enhance the convergence and diversity of the population through the combination of the pre-transfer learning stage and the transfer learning and validation stage when environmental changes occur. In the pre-transfer learning stage, a suitable target domain, source domain, and validation classifier sample sets are generated guided by historical information. In the transfer learning and validation stage, the TrAdaboost technique to transfer knowledge from the target to the source domain, with the results verified by two validation classifiers to mitigate negative transfer. Experimental results demonstrate that our proposed algorithm outperforms four competing algorithms in terms of diversity and convergence on a widely recognized benchmark suite. © 2024 IEEE.

关键词： Dynamic multiobjective optimization evolutionary algorithm transfer learning

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UAV-Mounted Intelligent Reflecting Surface in Maritime Wireless Powered Communication Network

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China Communications 2025年第3期22卷 254-269页

作者： Liu Yuan Han Fengxia Zhao Shengjie School of Information Science and Electrical Engineering Shandong Jiaotong UniversityJinan 250357China College of Electronic and Information Engineering Tongji UniversityShanghai 201804China School of Software Engineering Tongji UniversityShanghai 201804China Engineering Research Center of Key Software Technologies for Smart City Perception and Planning Ministry of EducationShanghai 200003China Key Laboratory of Embedded System and Service Computing Tongji University Shanghai 201804China

Intelligent reflecting surface(IRS)assisted with the wireless powered communication network(WPCN)can enhance the desired signal energy and carry out the power-sustaining problem in ocean monitoring *** this paper,we investigate a reliable communication structure where multiple buoys transmit data to a base station(BS)with the help of the unmanned aerial vehicle(UAV)-mounted IRS and harvest energy from the base station *** organically combine WPCN with maritime data collection scenario,a scheduling protocol that employs the time division multiple access(TDMA)is proposed to serve multiple buoys for uplink data ***,we compare the full-duplex(FD)and half-duplex(HD)mechanisms in the maritime data collection system to illustrate different performances under these two *** maximize the fair energy efficiency under the energy harvesting constraints,a joint optimization problem on user association,BS transmit power,UAV’s trajectory and IRS’s phase shift is *** solve the non-convex problem,the original problem is decoupled into several subproblems,and successive convex optimization and block coordinate descent(BCD)methods are employed obtain the near-optimal solutions *** results demonstrate that the UAV-mounted IRS can significantly improve energy efficiency in our considered system.

关键词： full-duplex IRS joint optimization TDMA UAV WPCN

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Intelligent Blocking and Prevention of SARS-CoV-2 Based on Evolutionary Reinforcement Learning 13

Intelligent Blocking and Prevention of SARS-CoV-2 Based on E...

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13th IEEE Congress on Evolutionary Computation, CEC 2024

作者： He, Chengwei Hong, Huaping Ma, Lijia Zhu, Qingling Bai, Yuan College of Computer Science and Software Engineering Shenzhen University Shenzhen518060 China Shenzhen University National Engineering Laboratory for Big Data System Computing Technology Shenzhen518060 China

ISBN: (纸本)9798350308365

In recent years, the global repercussions of SARS-CoV-2 and its variants have posed significant challenges to various areas, including the economic order, transportation, healthcare, and education, and the mitigation and prevention of SARS-CoV-2 and other infectious diseases have received much attention. This paper tries to develop a rational and effective intervention strategy in response to the dynamic evolution of the SARS-CoV-2 epidemic. To address this issue, we first use the SEIR model to analyze the population distribution under the SARS-CoV-2 epidemic, and then integrate a deep Q-neural network (DQN) to reflect an economic quantification model contextualized within the SARS-CoV-2 scenario. Next, we propose an evolutionary deep reinforcement learning to generate an optimal and adaptive intervention strategy, by optimizing the weight sequence of the DQN. The experimental results show the effectiveness of the proposed method in maximizing economic benefits, while ensuring the uninterrupted functionality of medical institutions. Importantly, the learned intervention strategy exhibits the applicability to other infectious diseases. © 2024 IEEE.

关键词： Deep reinforcement learning

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SlotFusion: Object-Centric Audiovisual Feature Fusion with Slot Attention for Remote Sensing Scene Recognition

SlotFusion: Object-Centric Audiovisual Feature Fusion with S...

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2025 IEEE International Conference on Acoustics, Speech, and Signal Processing, ICASSP 2025

作者： Han, Fangzhou Yu, Tianyi Zhang, Lamei Si, Lingyu Zhang, Yiqi Dept. of Information Engineering Harbin Institute of Technology Harbin China National Key Laboratory of Space Integrated Information System Institute of Software Chinese Academy of Sciences Beijing China Institute of Software Chinese Academy of Sciences Beijing China

ISBN: (纸本)9798350368741

Despite significant advancements in remote sensing multimodal learning, particularly in image-image feature fusion, the exploration of audio-image feature fusion remains insufficient. Given the complexity and redundancy of ground objects in remote sensing images, accurately aligning audio features with image features during the fusion process is a critical challenge. In this paper, we introduce an object-centric feature fusion method named SlotFusion. By employing a slot attention-based feature decoupling module and a slot-based audiovisual feature fusion module, we transform modality features with complex semantic information into a set of slot features corresponding to object units and use gated activation units to adaptively implement object-centric feature fusion. Experiments on the Audio Visual Aerial Scene Recognition dataset (ADVANCE) demonstrate that the proposed SlotFusion significantly improves remote sensing scene recognition performance, with a 7.04% increase in overall accuracy compared to previous methods, achieving state-of-the-art results. © 2025 IEEE.

关键词： Audiovisual feature fusion Gated feature fusion Object-centric learning Slot attention

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