Bio-integrated microrobots (BIMs), which are fabricated with biofriendly materials, biological units (e.g. cells or biomolecules), or cell-material hybrids have emerged as a promising technology for minimally invasive...
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Bio-integrated microrobots (BIMs), which are fabricated with biofriendly materials, biological units (e.g. cells or biomolecules), or cell-material hybrids have emerged as a promising technology for minimally invasive biomedicine. The diminutive size and flexible structures enable BIMs to navigate within narrow, deep, and challenging-to-reach in vivo regions, performing biopsy, diagnostic, drug delivery, and therapeutic functions with minimal invasiveness. However, the clinical deployment of BIMs is a highly orchestrated task that requires consideration of material properties, structural design, locomotion, observation, therapeutic outcomes, and side effects on cells and tissues, etc. In this review, we review and discuss the latest advances in the bio-integrated microrobot domain, evaluating various methods associated with materials, fabrication, actuation, and the implementation of biomedical functions in BIMs. By comparing the advantages and shortcomings of these techniques, this review highlights the challenges and future trends in highly intelligent bio-integrated microrobots, which have huge potential in minimally invasive biomedicine.
Soft materials including elastomers and hydrogels are playing critical roles in a variety of fields,including bioelectrodes,batteries,supercapacitors,biomedical scaffolds,and solar vapor *** hydrophobic sponges(i.e.,m...
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Soft materials including elastomers and hydrogels are playing critical roles in a variety of fields,including bioelectrodes,batteries,supercapacitors,biomedical scaffolds,and solar vapor *** hydrophobic sponges(i.e.,mechanical robustness,elasticity and macroscopic porous structure)and hydrophilic hydrogels(i.e.,autonomous water absorption and transportation,biocompatibility)within one unit could readily combine the complementary characters from each component,making a number of future research directions and applications *** propose a simple yet effective strategy to construct sponge-hydrogel hybrid structures with robust hydrophobic-hydrophilic *** sponge scaffold imparts the sponges-hydrogel hybrids with desirable mechanical robustness,elasticity and macroscopic *** the other hand,the incorporated hydrogel component endows the hybrids with high water content(98 wt%hydrogel and 2 wt%sponge),superior compatibility,and nanoscale pores allowing for storage and transportation of various chemical and biological *** further demonstrate that the introduction of hydrophilic hydrogel components could effectively improve the liquid absorption capability,blood coagulation rate,hemostatic capacity and hemocompatibility,thus promising as hemostatic agents.
In most image processing applications, the raw data acquired by an image sensor passes through a demosaicing algorithm in order to obtain a full color image. The demosaicing step can take time and resources that are o...
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Nowadays there are many computer vision algorithms dedicated to solve the problem of object detection, from many different perspectives. Many of these algorithms take a considerable processing time even for low resolu...
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An Active Disturbance Rejection based solution is proposed for the position control of a standard inverted pendulum system, demonstrating a largely model independent design that is distinctly different from existing m...
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ISBN:
(纸本)9781479947249
An Active Disturbance Rejection based solution is proposed for the position control of a standard inverted pendulum system, demonstrating a largely model independent design that is distinctly different from existing model-based designs from classical as well as modern control theory. The quality of the control loop is further improved with a unique double disturbance observer design, which rejects independently the disturbance and uncertainty in both the pendulum itself and the cart that carries it. This proposed approach offers a promising and practical solution because it's intuitive to understand and easy to tune, in addition to its strong performance and effectiveness shown in both simulation study and real time experimentation.
In this paper we present SPADES, an interactive graphics based software package for SPAtial mechanismDESign. The program provides a platform for the synthesis of a mechanism that guides a body through either three or ...
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Today, exoskeletons are widely applied to provide walking assistance for patients with lower limb motor incapacity. Most existing exoskeletons are under-actuated, resulting in a series of problems, e.g., interference ...
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Today, exoskeletons are widely applied to provide walking assistance for patients with lower limb motor incapacity. Most existing exoskeletons are under-actuated, resulting in a series of problems, e.g., interference and unnatural gait during walking. In this study, we propose a novel intelligent autonomous lower extremity exoskeleton(Auto-LEE), aiming at improving the user experience of wearable walking aids and extending their application *** traditional exoskeletons, Auto-LEE has 10 degrees of freedom, and all the joints are actuated independently by direct current motors, which allows the robot to maintain balance in aiding walking without extra *** new exoskeleton is designed and developed with a modular structure concept and multi-modal human-robot interfaces are considered in the control system. To validate the ability of self-balancing bipedal walking, three general algorithms for generating walking patterns are researched, and a preliminary experiment is implemented.
The path of the snake-like robot has no repetition because its motion is influenced by manifold indeterminate factors such as ground condition, mechanism's vibration and motor voltage's variety. A novel path p...
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The path of the snake-like robot has no repetition because its motion is influenced by manifold indeterminate factors such as ground condition, mechanism's vibration and motor voltage's variety. A novel path planning technique based on Serpenoid curve and Genetic algorithms (GAs) has been proposed to control the snake-like robot in Shenyang Institute of Automation (SIA, China). Firstly, the ranges of the path and the curvature deviation have been calculated approximately and set as the bounds of Genetic algorithms. Then using real time dual Genetic algorithms, this path planning technique not only can decide the shortest path and the minimum curvature deviation, but also can limit the motion error's influence. Simulation results show that the results of the second layer of GAs are more available than that of the first layer of GAs and this novel technique is effective for the path planning of the SIA snake-like robot.
This paper proposes a four-wheel mobile robot that uses passive star-wheel configuration to climb stairs. Without adding any control complexity, the robot can climb a standard indoor staircase of 15 × 28cm at a s...
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This paper presents the design and validation of an Extend Kalman Filter (EKF) for Simultaneous Localization and Mapping with Moving Objects Tracking (SLAMMOT) with application to unmanned aerial vehicles (UAVs) in un...
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This paper presents the design and validation of an Extend Kalman Filter (EKF) for Simultaneous Localization and Mapping with Moving Objects Tracking (SLAMMOT) with application to unmanned aerial vehicles (UAVs) in uncertain and dynamic environments. The proposed solution includes the tracking of Moving Objects (MO) using the Multiple Hypothesis Tracking (MHT) method, as well as the identification of the motion models of the environment's objects applying the Interacting Multiple Model (IMM) algorithm. The consistency and performance of the devised SLAMMOT filter is successfully confirmed with simulation results.
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