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U.S. SHIPBUILDING: THE SEVENTIES IN RETROSPECT —THE PROSPECTS FOR THE EIGHTIES

Naval Engineers Journal 1980年第4期92卷 25-38页

作者： FISHER, JAMES R. COADY, PHILIP USN Capt. James Ronald Fisher USN is a graduate of the U.S. Naval Academy. Class of 1958. has his M.A. degree in Management and is an Engineering Duty Officer (ED). He has served in a Destroyer and four Attack and Fleet Ballistic Missile Submarines as Training Officer of the Nuclear Propulsion Unit. West Milton N. Y. and at the Charleston Naval Shipyard where he also was the Chairman of the ASNE Charleston Section. He was ordered to the National Defense University from duty in the Industrial Management Directorate Naval Sea Systems Command (NAVSEA). and has just recently been reassigned to the Submarine Platform Directorate at NA VSEA. Cdr. Philip Coady USN is a graduate of Tufts University from which he received his A.B. degree in 1963 and also the Naval Postgraduate School. Monterey. Calif. from which he received his M.S. degree in 1972. His sea experience has been predominently in Destroyers. most recently as Executive Officer of the USS Claude V. Ricketts (DDG-S) and has had two tours in the Office of the Chief of Naval Operations (OP-090) his latest being that of Special Assistant for Financial Management to the Director of Navy Program Planning (OP-090). Currently he is under orders to assume command of the USS Conolly (DD-979).

This paper reviews the recent turbulent history of the U.S. Shipbuilding Industry, its present status, and its prospects for the decade ahead. The Authors suggest that current maritime policy and the trend of market f...

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Mo-Terminated Edges in Mos2 for Site-Specific Hydrolysis and DNA Cleavage

SSRN

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SSRN 2024年

作者： Wang, Cong Wu, Menghan Li, Muqing Zhao, Yingcan Zhao, Mingchuang Zhang, Yunhao Bai, Yichao Gao, Jianxiang Wang, Xiaoxia Tian, Xilin Zhang, Han Chang, Liang Zou, Xiaolong Liu, Bilu Kang, Feiyu Terrones, Mauricio Lei, Yu Institute of Materials Research Shenzhen Key Laboratory of Advanced Layered Materials for Value-added Applications Guangdong Provincial Key Laboratory of Thermal Management Engineering and Materials Center of Double Helix Tsinghua Shenzhen International Graduate School Tsinghua University Shenzhen518055 China Institute of Materials Research Shenzhen Geim Graphene Center Shenzhen Key Laboratory of Advanced Layered Materials for Value-added Applications Tsinghua-Berkeley Shenzhen Institute Tsinghua Shenzhen International Graduate School Tsinghua University Shenzhen518055 China Environmental Science Program Department of Life Sciences Beijing Normal University-Hong Kong Baptist University United International College Guangdong 519087 China Tsinghua Shenzhen International Graduate School Tsinghua University Shenzhen518055 China Department of Physics Department of Chemistry Department of Materials Sciences Center for 2-Dimensional and Layered Materials The Pennsylvania State University University Park PA16802 United States International Collaborative Laboratory of 2D Materials for Optoelectronics Science and Technology Ministry of Education Institute of Microscale Optoelectronics Shenzhen University Shenzhen518060 China Key Laboratory of Optoelectronic Devices and Systems China

The hydrolysis of DNA serves as the foundational principle for gene engineering that enable precise gene cleavage at the molecular level. This process typically occurs in biological nucleases, which exhibit nucleobase-selective and catalytic hydrolysis capabilities rarely replicated in abiotic nanomaterials. Here, we demonstrate that molybdenum-terminated (Mo-terminated) edges of molybdenum disulfide (MoS2) possess the unique ability to abstract a proton (H+) from water molecules, thereby facilitating catalytic hydrolysis reactions that cleave the phosphodiester bonds in DNA through the action of hydroxide ions. The enhanced proton absorption at Mo-terminated edges of MoS2 significantly reduces the activation energy required for the DNA hydrolysis reaction. Furthermore, the favorable interaction between the Mo-terminated edges and thymine nucleobases promotes both charge transfer and P-O bond cleavage, enabling targeted DNA hydrolysis at 'TTTTTTT' sequences under dark conditions. This discovery underscores the potential of MoS2 as a stable, efficient nanosystem for precise genetic editing, heralding advanced applications in the field of gene engineering. © 2024, The Authors. All rights reserved.

关键词： DNA sequences

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Entrepreneurial Mindfulness Based on Artificial Intelligence

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Journal of Physics: Conference Series 2020年第1期1641卷

作者： Yasinta Indrianti Sasmoko Nor Fadila Mohd Amin Sucianna Ghadati Rabiha Nugroho Juli Setiadi Agustinus Dedy Handrimurtjahjo Muktiono Waspodo Entrepreneurship Department Podomoro University Jakarta Indonesia 11470 Primary Teacher Education Department Faculty of Humanities Bina Nusantara University Jakarta Indonesia 11480 Department of Technical and Engineering Education School of Education Faculty of Social Sciences and Humanities Universiti Teknologi Malaysia Malaysia Information Systems Department Binus Online Learning Bina Nusantara University Jakarta Indonesia 11480 Management Department BINUS Business School Undergraduate Program Bina Nusantara University Jakarta Indonesia 11480 Center for Research on Education and Culture Policy Ministry of Education and Culture of the Republic of Indonesia Jakarta Indonesia

The ability to self-diagnose to build capacity as an entrepreneur is something that is important in order to bridge the development of self-competence needed in the industrial era 4.0. This ability is expected to bring up a condition in which a person has full active awareness of the awakening of the entrepreneurial spirit within himself to then produce a productive person called Entrepreneurial Mindfulness. This study aims to develop self-detection tools about Entrepreneurial Mindfulness through an artificial intelligence-based website for students and alumni who are entrepreneurs. The research method used is the Neuroresearch method for developing Entrepreneurial Mindfulness measurement tools and the waterfall method for developing Artificial Intelligence-based websites. The results of research in the form of an Artificial Intelligence-based website about Entrepreneurial Mindfulness where the website will be able to provide profiling based on diagnoses made related to the level of Entrepreneurial Mindfulness owned by students and alumni in implementing entrepreneurial practices.

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THE IMPACT OF DESIGN PRACTICES ON SHIP SIZE AND COST

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NAVAL ENGINEERS JOURNAL 1982年第2期94卷 68-86页

作者： KEHOE, JW BROWER, KS MEIER, HA Capt. James W. Kehoe Jr. USN(Ret.):who is recently retired from 36 years of naval service is well known for his recent work in conducting comparative engineering analyses of U.S. and foreign warship design practices at the Naval Sea Systems Command Washington D.C. He is currently a partner in Spectrum Associates Inc. Falls Church Virginia where he is engaged in ship design and weapon system engineering analysis. Commissioned in 1952 his sea duty aboard three destroyers and three aircraft carriers included command of theUSS John R. Pierce (DD-753)and engineer officer of theUSS Wasp (CVS-18).Ashore he has had duty in nuclear weapons the POLARIS missile program and instructing in project management. He holds a BS in mathematics from Stonehill College Massachusetts (1952) and an MA in education from San Diego State College (1959). A frequent contributor to theNaval Engineers Journaland theU.S. Naval Institute Proceedingshe has published a number of articles on U.S. Soviet and other foreign warship design practices and on U.S. and Soviet aircraft tank missile and electronic design practices. Kenneth S. Brower:is a partner in Spectrum Associates Inc. Falls Church Virginia which he founded in June 1978. He graduated from the University of Michigan in 1965 with a Bachelor's Degree in Naval Architecture. Mr. Brower has contributed to the design and construction of numerous merchant ships and warships the latter of which include the CG-47 project Arapaho the FDL and DX projects the new NATO frigate for the ‘90s DDGX and FFX projects as well as several frigates developed for Foreign Military Sales. Since 1972 he has actively supported the Naval Sea Systems Command's Comparative Naval Architecture Program. During this period Mr. Brower has contributed to or been the author of numerous widely distributed technical reports on international ship design practices. Recently Mr. Brower has contributed as an analyst editor and author of an extensive assessment of the engineering design practices o

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NAVAL COMMUNICATIONS - A SYSTEM WITHIN A SYSTEM

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NAVAL ENGINEERS JOURNAL 1968年第3期80卷 445-&页

作者： SHERWIN, SA USN The author was graduated from the United States Naval Academy in 1940 and reported to the USS OKLAHOMA in which he served until December 7 1941. He was aboard during the Japanese attack on Pearl Harbor during which the ship was capsized. During World War II he served in the USS INDIANA and the USS HANCOCK of which he was gunnery officer until July 1945. For the next three years he studied electronics engineering at the U. S. Naval Postgraduate School at Annapolis Maryland. Since that time he has served on the staff Commander Destroyer Force U. S. Atlantic Fleet the Bureau of Ships (a total of seven years in shipboard electronics and as Head of the Radar Design Branch) at Long Beach Naval Shipyard at the Branch office of the Office of Naval Research in London England and most recently four years as Production Officer of the Pearl Harbor Naval Shipyard. Since August 1967 he has been Deputy Commander for the Commodity Acquisition Directorate reporting to the Commander Naval Electronic Systems Command. In 1963 he completed the Advanced Management Program at Harvard University. His previous papers include “The Coordinated Ship Electronics Design Concept” published in this Journal in 1962 and with Captain R. T. Miller USN “The Impact of Electronics on Warship Design” presented at the annual meeting of the Society of Naval Architects and Marine Engineers in November 1962.

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Forecasting: theory and practice

arXiv

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arXiv 2020年

作者： Petropoulos, Fotios Apiletti, Daniele Assimakopoulos, Vassilios Babai, Mohamed Zied Barrow, Devon K. Taieb, Souhaib Ben Bergmeir, Christoph Bessa, Ricardo J. Bijak, Jakub Boylan, John E. Browell, Jethro Carnevale, Claudio Castle, Jennifer L. Cirillo, Pasquale Clements, Michael P. Cordeiro, Clara Oliveira, Fernando Luiz Cyrino de Baets, Shari Dokumentov, Alexander Ellison, Joanne Fiszeder, Piotr Franses, Philip Hans Frazier, David T. Gilliland, Michael Gönül, M. Sinan Goodwin, Paul Grossi, Luigi Grushka-Cockayne, Yael Guidolin, Mariangela Guidolin, Massimo Gunter, Ulrich Guo, Xiaojia Guseo, Renato Harvey, Nigel Hendry, David F. Hollyman, Ross Januschowski, Tim Jeon, Jooyoung Jose, Victor Richmond R. Kang, Yanfei Koehler, Anne B. Kolassa, Stephan Kourentzes, Nikolaos Leva, Sonia Li, Feng Litsiou, Konstantia Makridakis, Spyros Martin, Gael M. Martinez, Andrew B. Meeran, Sheik Modis, Theodore Nikolopoulos, Konstantinos Önkal, Dilek Paccagnini, Alessia Panagiotelis, Anastasios Panapakidis, Ioannis Pavía, Jose M. Pedio, Manuela Pedregal, Diego J. Pinson, Pierre Ramos, Patrícia Rapach, David E. Reade, J. James Rostami-Tabar, Bahman Rubaszek, Michal Sermpinis, Georgios Shang, Han Lin Spiliotis, Evangelos Syntetos, Aris A. Talagala, Priyanga Dilini Talagala, Thiyanga S. Tashman, Len Thomakos, Dimitrios Thorarinsdottir, Thordis Todini, Ezio Arenas, Juan Ramón Trapero Wang, Xiaoqian Winkler, Robert L. Yusupova, Alisa Ziel, Florian School of Management University of Bath United Kingdom Politecnico di Torino Turin Italy Forecasting and Strategy Unit School of Electrical and Computer Engineering National Technical University of Athens Greece Kedge Business School France Department of Management Birmingham Business School University of Birmingham United Kingdom Belgium Faculty of Information Technology Monash University Melbourne Australia INESC TEC – Institute for Systems and Computer Engineering Technology and Science Porto Portugal Department of Social Statistics and Demography University of Southampton United Kingdom Centre for Marketing Analytics and Forecasting Lancaster University Management School Lancaster University United Kingdom School of Mathematics and Statistics University of Glasgow United Kingdom Department of Mechanical and Industrial Engineering University of Brescia Italy Magdalen College University of Oxford United Kingdom ZHAW School of Management and Law Zurich University of Applied Sciences Switzerland ICMA Centre Henley Business School University of Reading United Kingdom Faculdade de Ciências e Tecnologia Universidade do Algarve Portugal CEAUL Faculdade de Ciências Universidade de Lisboa Portugal Brazil Department of Business Informatics and Operations Management Faculty of Economics and Business Administration Universiteit Gent Belgium Let’s Forecast Australia Faculty of Economic Sciences and Management Nicolaus Copernicus University in Torun Poland Econometric Institute Erasmus School of Economics Rotterdam Netherlands Department of Econometrics and Business Statistics Monash University Melbourne Australia SAS United States Newcastle Business School Northumbria University Newcastle upon Tyne United Kingdom Department of Statistical Sciences University of Padua Italy Darden School of Business University of Virginia United States Finance Department Bocconi University Baffi-CAREFIN Centre Milan Italy Department of Tourism and Service Management MODUL Un

Forecasting has always been at the forefront of decision making and planning. The uncertainty that surrounds the future is both exciting and challenging, with individuals and organisations seeking to minimise risks and maximise utilities. The large number of forecasting applications calls for a diverse set of forecasting methods to tackle real-life challenges. This article provides a non-systematic review of the theory and the practice of forecasting. We provide an overview of a wide range of theoretical, state-of-the-art models, methods, principles, and approaches to prepare, produce, organise, and evaluate forecasts. We then demonstrate how such theoretical concepts are applied in a variety of real-life contexts. We do not claim that this review is an exhaustive list of methods and applications. However, we wish that our encyclopedic presentation will offer a point of reference for the rich work that has been undertaken over the last decades, with some key insights for the future of forecasting theory and practice. Given its encyclopedic nature, the intended mode of reading is non-linear. We offer cross-references to allow the readers to navigate through the various topics. We complement the theoretical concepts and applications covered by large lists of free or open-source software implementations and publicly-available databases. © 2020, CC BY.

关键词： Forecasting

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Employee Perceptions of Workplace Factors That Will Most Improve Their Performance

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Performance Improvement Quarterly 1996年第2期9卷

作者： Peter J. Dean Martha Ray Dean Rebecca M. Rebalsky University of Tennessee Department Head for Human Resources Development at the University of Tennessee and editor of Performance Improvement Quarterly. He is Vice President of Research for the International Board of Standards for Training Performance and Instruction and is editor of Performance Engineering at Work. Mailing address: University of Tennessee 1215 W. Cumberland Avenue Rm 110 Knoxville TN 37996‐1900. Philadelphia College of Bible Extensive experience in design development implementation and evaluation of instruction performance improvement and management systems in the public and private sectors. She also teaches graduate education courses at Philadelphia College of Bible. Mailing address: Philadelphia College of Bible 200 Manor Avenue Langhorne PA 19047‐2990. E‐mail: 76173.1257@*** Penn State University at Great Valley Graduate of the Master of Management Program at Penn State University's Great Valley Campus. Her area of specialization is health care administration. Mailing address: Pennsylvania State University Great Valley Management Program 30 East Swedesford Road Malvern PA. 19355.

Training is often the performance improvement solution of choice, yet how often does the best training not yield performance improvement? There is a growing body of evidence that indicates that many times performance improvement can be achieved faster, cheaper, and better by altering factors in the workplace than by training. This article describes an activity designed to illustrate the importance of workplace factors in improving performance and a study that demonstrates its validity. Results of the study indicate that two‐thirds of the participants believed the environmental factors of information, resources, and incentives needed improving in order to enable them to improve their own performance.

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U.S. AND FOREIGN HULL FORM, MACHINERY AND STRUCTURAL DESIGN PRACTICES

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Naval Engineers Journal 1983年第6期95卷 36-53页

作者： KEHOE, JAMES W. BROWER, KENNETH S. MEIER, HERBERT A. RUNNERSTROM, CDR. ERIC James W. Kehoe Jr. is well known for his work in conducting comparative naval architecture studies of U.S. and foreign warship design practices for which he received the ASNE Gold Medal for 1981 and the Legion of Merit. He is currently a partner in Spectrum Associates Incorporated Arlington Virginia where he is engaged in the feasibility and concept design of naval ships and in continuing his comparative engineering analyses of U.S. and foreign warships. Prior to his retirement from the U.S. Navy as a Captain in 1982 his naval career involved sea duty aboard three destroyers and three aircraft carriers including command of the USS John R. Pierce (DD-753) and engineer officer of the USS Wasp (CVS-18). Ashore he had duty at the Naval Sea Systems Command where he directed the Comparative Naval Architecture Program as an instructor in project management in the Polaris missile project and as a nuclear weapons officer. He holds a B.S. in mathematics from Stonehill College Massachusetts (1952) and an MA in education from San Diego State College (1959). A frequent contributor to the Naval Engineers Journal U.S. Naval Institute Proceedings and the International Defense Review he has published a number of articles on U.S. Soviet and other foreign warship design practices and the effects of design practices on ship size and cost. Kenneth S. Brower is a partner in Spectrum Associates Incorporated Arlington Virginia which he founded in June 1978. He graduated from the University of Michigan in 1965 with a Bachelor's Degree in Naval Architecture. Mr. Brower has contributed to the design and construction of numerous merchant ships and warships the latter of which include the CG-47 project Arapaho the FDL and DX projects the new NATO Frigates Replacement for the ‘90's DDGX and FFX projects as well as several frigate developed for Foreign Military Sales. Since 1972 he has actively supported the Naval Sea Systems Command's Comparative Naval Architecture Program. During this period Mr. Brower has contribute

There are two principal benefits to conducting comparative engineering analyses of U.S. and foreign ship design practices and criteria: 1) they offer an opportunity to identify clever ideas from which the U.S. can benefit, and 2) they cause us to assess U.S. design practices critically that we may have been taking for granted or may have been accepting as inviolable. The results of a comparative analysis of U.S. and foreign hull form, machinery, and structural design practices are reported in this paper. Numerous studies of U.S. and foreign warships have shown that the hull form, machinery, and structural design practices of various navies differ considerably. Although most large navies operate their ships in generally similar environments, each country has developed its own unique style of hull form. Based on an assessment of foreign hull form design practices, the U.S. Navy has recently developed a style of hull form that offers improved stability and seakeeping performance and which facilitates the arrangement of internal functions. Foreign ships generally have a tighter machinery arrangement than comparable U.S. ships. However, this is not necessarily achieved by accepting less subsystem performance or by sacrificing redundancy. The tightness of foreign machinery plants seems to be achieved by tighter management control over the ship design and acquisition process. In addition, foreign navies appear to be more flexible in adjusting to a new technology such as that which occurred during the change from steam to gas turbine propulsion. U.S. ships appear to be constructed to more rigorous structural detail design standards than foreign ships. The structural configuration of foreign ships, including the integration of web frames, longitudinal girders, and stanchions also differs from U.S. practice. The configuration of ship structure and the value of rigorous U.S. structural design practices are worthy of additional research. The results of the study reported in thi

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Left ventricular hypertrophy detection using electrocardiographic signal

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Scientific reports 2023年第1期13卷 2556页

作者： Cheng-Wei Liu Fu-Hsing Wu Yu-Lun Hu Ren-Hao Pan Chuen-Horng Lin Yung-Fu Chen Guo-Shiang Tseng Yung-Kuan Chan Ching-Lin Wang Division of Cardiology Department of Internal Medicine Tri-Service General Hospital Songshan Branch National Defense Medical Center Taipei Taiwan. Bachelor Degree Program of Artificial Intelligence National Taichung University of Science and Technology Taichung Taiwan. Department of Management Information Systems National Chung-Hsing University Taichung Taiwan. La Vida Tec. Co. Ltd. Taichung Taiwan. Preventive Medicine Center National Yang Ming Chiao Tung University Taipei Taiwan. Department of Information Management Tunghai University Taichung Taiwan. Department of Computer Science and Information Engineering National Taichung University of Science and Technology Taichung Taiwan. Department of Dental Technology and Materials Science Central Taiwan University of Science and Technology Taichung Taiwan. Division of Cardiology Department of Internal Medicine Taoyuan Armed Force General Hospital Hsinchu Branch Hsinchu Taiwan. Department of Management Information Systems National Chung-Hsing University Taichung Taiwan. ykchan@nchu.edu.tw. Department of Information Management National Chin-Yi University of Technology Taichung Taiwan. clwang@ncut.edu.tw.

Left ventricular hypertrophy (LVH) indicates subclinical organ damage, associating with the incidence of cardiovascular diseases. From the medical perspective, electrocardiogram (ECG) is a low-cost, non-invasive, and easily reproducible tool that is often used as a preliminary diagnosis for the detection of heart disease. Nowadays, there are many criteria for assessing LVH by ECG. These criteria usually include that voltage combination of RS peaks in multi-lead ECG must be greater than one or more thresholds for diagnosis. We developed a system for detecting LVH using ECG signals by two steps: firstly, the R-peak and S-valley amplitudes of the 12-lead ECG were extracted to automatically obtain a total of 24 features and ECG beats of each case (LVH or non-LVH) were segmented; secondly, a back propagation neural network (BPN) was trained using a dataset with these features. Echocardiography (ECHO) was used as the gold standard for diagnosing LVH. The number of LVH cases (of a Taiwanese population) identified was 173. As each ECG sequence generally included 8 to 13 cycles (heartbeats) due to differences in heart rate, etc., we identified 1466 ECG cycles of LVH patients after beat segmentation. Results showed that our BPN model for detecting LVH reached the testing accuracy, precision, sensitivity, and specificity of 0.961, 0.958, 0.966 and 0.956, respectively. Detection performances of our BPN model, on the whole, outperform 7 methods using ECG criteria and many ECG-based artificial intelligence (AI) models reported previously for detecting LVH.

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The 2022 report of the Lancet Countdown on health and climate change: health at the mercy of fossil fuels (vol 400, pg 1619, 2022)

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LANCET 2022年第10365期400卷 1766-1766页

作者： Romanello, M. Di Napoli, C. Drummond, P. Institute for Global Health University College London London UK School of Agriculture Policy and Development University of Reading Reading UK Institute for Sustainable Resources University College London London UK Department of Global Health Centre for Health and the Global Environment University of Washington Seattle WA USA UCL Energy Institute University College London London UK Department of Health Sciences University of York York UK Department of Meteorology University of Reading Reading UK Institute for Risk and Disaster Reduction University College London London UK School of Earth and Environment University of Leeds Leeds UK Centre on Climate Change and Planetary Health London School of Hygiene & Tropical Medicine London UK School of Population Health University of Melbourne Melbourne VIC Australia Department of Earth System Science Tsinghua University Beijing China Mercator Research Institute on Global Commons and Climate Change Berlin Germany Department of Environment Climate Change and Health World Health Organization Geneva Switzerland Institute of Environmental Sciences University of Geneva Geneva Switzerland Cardiovascular Epidemiology Unit Department of Public Health & Primary Care University of Cambridge Cambridge UK School of Government University of Birmingham Birmingham UK Economic Analysis of Climate Impacts and Policy Division Centro Euro-Mediterraneo sui Cambiamenti Climatici Venice Italy Institute for Environmental Design and Engineering University College London London UK Natural Resources Institute University of Greenwich London UK Department of Environmental Health Sciences and Yale Center on Climate Change and Health Yale University New Haven CT USA Department of Civil and Environmental Engineering Northeastern University Boston MA USA Department of Fish and Wildlife Conservation Virginia Polytechnic Institute and State University Blacksburg VA USA Department of Geography University College London London UK NU

With advancements in the science of detection and attribution studies, the influence of climate change over many events has now been quantified. Because of the rapidly increasing temperatures, vulnerable populations (adults older than 65 years, and children younger than one year of age) were exposed to 3·7 billion more heatwave days in 2021 than annually in 1986–2005 (indicator 1.1.2), and heat-related deaths increased by 68% between 2000–04 and 2017–21 (indicator 1.1.5), a death toll that was significantly exacerbated by the confluence of the COVID-19 pandemic. Despite the local cooling and overall health benefits of urban greenspaces, only 277 (27%) of 1038 global urban centres were at least moderately green in 2021 (indicator 2.2.3), and the number of households with air conditioning increased by 66% from 2000 to 2020, a maladaptive response that worsens the energy crisis and further increases urban heat, air pollution, and greenhouse gas emissions. [...]millions of people do not have access to the energy needed to keep their homes at healthy temperatures, preserve food and medication, and meet the seventh Sustainable Development Goal (to ensure access to affordable, reliable, sustainable, and modern energy for all). Aggravating this situation even further, governments continue to incentivise fossil fuel production and consumption: 69 (80%) of 86 countries reviewed had net-negative carbon prices (ie, provided a net subsidy to fossil fuels) for a net total of US$400 billion

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