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Association of Long-Term Ozone Exposure with the Incidence and Progression of Hypertension, diabetes, and Chronic Kidney disease: A National Retrospective Cohort Study

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SSRN 2024年

作者： Li, Yu-Ling Chang, Po-Ya Chuang, Ting-Wu Hsieh, Yi-Chen Wang, Bo-Sian Chen, Szu-Ying Chiou, Hung-Yi Institute of Population Health Sciences National Health Research Institutes Miaoli County Zhunan Taiwan Department of Leisure Industry and Health Promotion National Taipei University of Nursing and Health Sciences Taipei Taiwan Department of Molecular Parasitology and Tropical Diseases School of Medicine College of Medicine Taipei Medical University Taipei Taiwan Ph.D Program of Neural Regenerative Medicine College of Medical Science and Technology Taipei Medical University Taipei Taiwan Master Program in Applied Epidemiology College of Public Health Taipei Medical University Taipei Taiwan

Emerging evidence indicates particulate matter and nitrogen oxides are associated with increased risk of transition from healthy state to incident hypertension, diabetes, or chronic kidney disease (CKd) in the dynamic progression of these three chronic diseases. However, across different dynamic disease trajectories the associations of gaseous pollutants such as ozone remain unknown. This study aimed to investigate the long-term effects of exposure to ambient ozone on dynamic progression to multimorbidity, and consequent death from these diseases, with consideration of other air pollutants. This study included 9,256,945 participants from Taiwan’s National Health Insurance Research database between 2006 and 2021. Multimorbidity was defined as the coexistence of CKd and either hypertension or diabetes. The ordinary kriging method was used to estimate daily concentrations of ozone, sulfur dioxide, carbon monoxide, nitrogen dioxide, suspended fine particles, and suspended particles. We performed multi-state models to analyze the association between ambient air pollutants and dynamic progression of hypertension, diabetes, and CKd. during follow-up, 3,555,498 participants experienced hypertension, diabetes, or CKd;656,515 experienced multimorbidity;and 792,555 died. Ozone exposure was significantly associated with incidence of the results in all transitions. The hazard ratios of each IQR (3.57 ppb) increment in ozone for the transition to incident disease were 1.016 [95% confidence interval (CI): 1.014, 1.017], for the transition to death were 1.04 [95% CI: 1.036, 1.043], for the transition to multimorbidity were 1.015 [95% CI: 1.012, 1.017] after adjusting other risk factors. Furthermore, with each IQR increase of ozone, the hazard ratios for transition from the incidence disease to death and from multimorbidity to death were 1.03 [95% CI: 1.026, 1.033] and 1.007 [95% CI: 1.002, 1.013], respectively. Our results suggest that long-term exposure to ozone might be an import

关键词： Health insurance

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Learner Characteristics as Consequences of Active Learning

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Journal of physics: Conference Series 2019年第1期1340卷

作者： Jiratchaya phala Suthida Chamrat Ph.D student Doctor of Philosophy Program in Education (Science education) Faculty of Education Chiang Mai university Department of Curriculum Instruction and Learning Faculty of Education Chiang Mai University

This paper aims to explore the consequences of active learning implementation toward students' characteristics. Literature reviewing, and synthesizing intend to delineate the framework of active learning driven classroom where teachers lessen their own profile from lecturers into facilitators. By deploying active learning, students' multiple skills are activated and practiced. These skills, gradually, become students' characteristics. Reviewing and synthesizing from the existing literature and research reports indicate students' characteristics as possible outcomes of active learning in 12 traits: 1) students have a great opportunity to first-hand experience; 2) students create learning process and construct knowledge by themselves; 3) students learn and reflect from their experiences; 4) students develop higher order thinking; 5) students develop their learning skills; 6) students play important roles in learning which are also varied and diverse; 7) students highly participate in learning process; 8) students reach academic achievements with meaningful learning; 9) students build rapport with teachers and their peers; 10) students integrate information with their prior knowledge; 11) students develop positive attitudes and self-esteem; 12) students are enthusiastic, active, happy and joyful.

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The Nature of science Views among Intern General science Pre-Service Teachers

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Journal of physics: Conference Series 2019年第1期1340卷

作者： Somsak Gathong Suthida Chamrat Ph.D student Doctor of Philosophy Program in Education (Science education) Faculty of Education Chiang Mai University Department of Curriculum Instruction and Learning Faculty of Education Chiang Mai University

This research aimed to study the nature of science views of 23 students who are currently intern general science pre-service teachers in one of Rajabhat Universities in the North. The research instrument used in the study was: the nature view of science questionnaire developed by Haidar (1999) and the researcher has improved it in accordance with the curriculum of science and education in Thailand. The nature of science views had three aspects totally 27 items. There were 8 items for scientific world view, 4 items for the scientific knowledge inquiry, 6 items for scientific enterprise and they were totally 18 items and open-ended question on the nature of science views with three aspects of science in the world: 3 items for scientific world view, 3 items for scientific inquiry and 3 items for scientific enterprise. They were totally 9 items. Then the data were analyzed by grouping the answers and finding the percentage. The results of the research revealed that intern general science pre-service teachers had the same view of the nature of science that was consistent with 3 aspects of the traditional view. That were the 2nd aspect; scientific inquiry. The 1st aspect; scientific found that 91.30 %better understood consistent with the traditional view that working of a scientist must be based on a scientific method that has a definite sequence of steps. As the 2nd aspect; the scientific knowledge creation found that 78.26% had the consistency of understanding with the traditional concept. It stated that scientific knowledge is created by observation, survey or experiment. The 3rd aspect; evidence and imagination, and creative thinking, it affects the scientific knowledge creation. It showed that 73.91% had an understanding that is consistent with the traditional concept that scientists acquire scientific knowledge using only evidence-based. The findings indicated that intern general science pre-service teachers still have many points of view. The most necessary thing i

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Monitoring the navy's strategic reserve of ozone-depleting substances

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NAVAL ENGINEERS JOURNAL 2002年第4期114卷 95-104页

作者： Smith, dE Breslin, dA Toms, GS Norton, P DENNIS E. SMITH PH.D. is currently a statistical consultant for GEO-CENTERS INC. He received a B.A. in Mathematics (magna cum laude)from Wabash College and an M.S. in mathematics an M.S. in statistics and a Ph.D. in statistics from the University of Wisconsin. From November 1973 until February 1999 he was president and principal statistician at Desmatics Inc. where he participated in a number of studies involving the application of statistical methods to various technical problems in the Navy's environmental-protection and auxiliary-machinery programs. Dr. Smith was instrumental in developing the statistical procedures underlying the Navy's ODS reserve monitoring plan. DAVID A. BRESLIN P.E. is the director of technical operations for the Naval Surface Warfare Center and chairs the ASNE/SNAME Joint Committee on Environmental Engineering. He received a master of science in aerospace engineering from Virginia Tech a master of engineering administration in industrial and systems engineering from Virginia Tech and a bachelor of engineering in mechanical engineering from Stevens Institute of Technology. From 1993 to 1997 he was the program manager of the Naval Sea Systems Command's CFC and Halon Elimination Program and played a critical role in establishing the Navy's strategic reserve of ozone-depleting substances. Because of his many efforts he received a Stratospheric Ozone Protection Award in 1995 from the U.S. Environmental Protection Agency in recognition of “exceptional contributions to global environmental protection”. GREGORY S. TOMS P.E. is the CFC &Halon Elimination Program Manager for the Naval Sea Systems Command (NAVSEA). He received a master of science degree in mechanical engineering from the University of Maryland and a B.S. degree in mechanical engineering from West Virginia University. From 1984 to 1997 he was employed at the Naval Surface Warfare Center Carderock Division Annapolis Detachment (formerly David Taylor Research Center)where he worked on the development of advanced cent

The domestic production of the most powerful ozone-depleting substances (OdSs) has permanently ceased and the abundant supplies of a number of refrigerants, fire-fighting agents, and solvents, once taken for granted, are now a thing of the past. The Navy has adopted a successful strategy for addressing the threat posed by the unavailability of OdSs. That strategy includes relying on a strategic reserve of OdSs. Considering that the strategic reserve will play a critical role in sustained Fleet operations into the middle of the century, it is important to record the history of the reserve and to document lessons learned in order to educate future generations that may face similar challenges. This is the third of three papers that cover all aspects of the Navy's strategic reserve of OdSs. Breslin (1999) documented the history of the Navy's effort to size, establish, and monitor a reserve designed to support Fleet operations until the middle of the century. Breslin, Smith, and Toms (2000) addressed in detail the process used to estimate the required size of the reserve, including the survey method, statistical analyses, and sizing algorithms. This paper discusses the Navy's plan for monitoring the Navy's strategic reserves of OdSs and describes the methods used in the monitoring process. In particular it discusses the underlying assumptions and statistical techniques associated with the Navy's prediction of the expected drawdown of the reserves. A comparison of actual data, collected since the strategic reserves began operations in 1995, with the predicted reserve drawdown, is included in the paper.

关键词： Marine engineering

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A statistical method for estimating the life expectancy of certain shipboard equipment

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NAVAL ENGINEERS JOURNAL 2002年第1期114卷 27-32页

作者： Smith, dE Breslin, dA Toms, GS DENNIS E. SMITH PH.D. is a statistical consultant for Geo-Centers Inc. He received a B.A. in mathe-matics (magna cum laude) from Wabash College and an M.S. in mathematics an M.S. in statistics and a Ph.D. in statistics from the University of Wisconsin. From November 1973 until February 1999 he was President and Principal Statistician at Desmatics Inc. where he participated in a number of studies involving the application of statistical methods to various technical problems in the Navy's environmental-protection and auxiliary-machinery programs. Dr. Smith was instrumental in developing the statistical procedures underlying the Navy's ODS reserve monitoring plan. DAVID A. BRESLIN P.E. is the Director of Technical Operations for the Naval Surface Warfare Center and is the chairperson of ASNE's Committee on Environmental Engineering. He received a master of science degree in aerospace engineering from Virginia Tech a master of engineering administration in indus-trial & systems engineering from Virginia Tech and a bachelor of engineering in mechanical engineering from Stevens Institute of Technology. From 1993 to 1997 he was the program manager of the Naval Sea Systems Command's CFC & Halon Elimination Program and played a critical role in establishing the Navy's strategic reserve of ozone-depleting substances. Because of his many efforts he received a Stratospheric Ozone Protection Award in 1995 from the U.S. Environmental Protection Agency in recogni-tion of “exceptional contributions to global environmental protection”. GREGORY S. TOMS P.E. is the CFC & Halon Elimination Program Manager for the Naval Sea Systems Command (NAVSEA). He received a master of science degree in mechanical engineering from the University of Maryland and a B.S. degree in mechanical engineering from West Virginia University. From 1984 to 1997 he was employed at the Naval Surface Warfare Center Carderock Division Annapolis Detachment (formerly David Taylor Research Center) where he worked on the development of advanced cent

This paper reviews an inexpensive statistical-sampling methodology that can be used to determine the attrition rates of certain types of shipboard equipment. The methodology relies on surveys that are conducted in conjunction with regularly scheduled ship visits over a period of time and a statistical analysis of the survey results. The statistical technique allows for reasonably accurate estimates to be made of attrition rates. The specific example cited in this paper is related to galley-type refrigeration equipment, such as salad chillers, beverage dispensers, et cetera. In the case of galley-type refrigeration equipment, the Navy needs to know whether the Fleet's inventory of equipment relying on Class I Ozone-depleting Substances (OdSs) will be replaced through natural attrition by the end of fiscal year (FY) 2005, at which time supplies of OdS-based refrigerants will no longer be available for use by ship galleys. This paper outlines the process used to gather data, the analysis of the data, and concludes that the Navy's inventory of galley equipment using Class I OdSs will be replaced through natural attrition by the end of FY05. The methodology reviewed by this paper has wider applications. For various types of shipboard equipment, the methodology can also be used to estimate with reasonable accuracy life expectancies, configurations, conditions, and other items of interest.

关键词： Ship equipment

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16-IN GUN BLAST ANd THE BATTLESHIP REACTIVATION program

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NAVAL ENGINEERS JOURNAL 1987年第3期99卷 227-238页

作者： YAGLA, JJ The authorreceived his B. A. degree in science (physics) from the State College of Iowa in 1965. He received his M. S. degree in engineering mechanics in 1968 and his Ph.D in aerospace engineering and engineering science in 1981 from Arizona State University. He has done analytical and experimental research in the field of weapons blast since 1965 at the Naval Surface Weapons Center in Dahlgren Virginia. As a supervisory research mechanical engineer he was previously head of the Physical Response Analysis Branch Blast Effects Branch and Ship Engineering Branch. Dr. Yagla is the test development agent and was test conductor for the gun and missile structural test firings in USS Iowa class battleships. He is a consultant to the Naval Sea Systems Command battleship combat system engineer and the Naval Air Systems Command Cruise Missile Project for blast and structural response. He is presently analyzing shock and vibration problems for the Standard Missile Program Office.

Reactivated and modernized USS Iowa class battleships employ many new systems, none of which were designed to withstand blast from 16-inch guns. Placement of the new equipment was driven by the need to impose the smallest possible restrictions on the guns. The design problem was complicated by two factors: first, the blast overpressure field surrounding the gun had not been accurately measured with modern instruments. Second, the blast overpressure tolerance of several important systems was unknown. The problem was solved through judicious placement of the equipment so that work could begin on the ship. Meanwhile the pressure surrounding a 16-inch gun was measured at the dahlgren Laboratory. Mathematical functions describing the blast field were then used to design shipboard experiments in which the guns were fired at progressively more severe angles of train and elevation, while the equipment performance was carefully monitored. Four sets of shipboard experiments were required. Limiting values for the firing arcs have been determined, and the consequences of exceeding the recommended limits are now known.

关键词： WARSHIPS

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RESOLVING dIFFERENCES WITHIN THE REHABILITATION TEAM

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Rehabilitation Nursing 1984年第3期9卷 38-40页

作者： Margolis, Howard Fiorelli, Joseph S. Leonard, H. Skipton Howard Margolis received his EdD from Hofstra University. He is currently director of program development for Star Systems Consultation and Training in Philadelphia PA. He specializes in assisting health organizations improve productivity and service through the judicious use of their human resources. Joseph S. Fiorelli received his PhD in organizational development and training from Temple University and is currently director of education for Moss Rehabilitation Hospital in Philadelphia PA. He specializes in organizational problem solving psycho-educational processes and adult education. He is a frequent presenter and author in the areas of training and inter-disciplinary teamwork. H. Skipton Leonard Ph.D received his doctorate from the Research Center For Human Development NY University. He was a post doctoral fellow in group processes at the National Institute of Mental Health. He is currently a clinical psychologist in private practice in the Washington DC area and has just co-authored a text on nursing management.

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Self-Awareness for Autonomous systems

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PROCEEdINGS OF THE IEEE 2020年第7期108卷 971-975页

作者： dutt, Nikil Regazzoni, Carlo S. Rinner, Bernhard Yao, Xin Nikil Dutt (Fellow IEEE) received the Ph.D. degree from the University of Illinois at Urbana–Champaign Champaign IL USA in 1989.""He is currently a Distinguished Professor of computer science (CS) cognitive sciences and electrical engineering and computer sciences (EECS) with the University of California at Irvine Irvine CA USA. He is a coauthor of seven books. His research interests include embedded systems electronic design automation (EDA) computer architecture distributed systems healthcare Internet of Things (IoT) and brain-inspired architectures and computing.""Dr. Dutt is a Fellow of ACM. He was a recipient of the IFIP Silver Core Award. He has received numerous best paper awards. He serves as the Steering Committee Chair of the IEEE/ACM Embedded Systems Week (ESWEEK). He is also on the steering organizing and program committees of several premier EDA and embedded system design conferences and workshops. He has served on the Editorial Boards for the IEEE Transactions on Very Large Scale Integration (VLSI) Systems and the ACM Transactions on Embedded Computing Systems and also previously served as the Editor-in-Chief (EiC) for the ACM Transactions on Design Automation of Electronic Systems. He served on the Advisory Boards of the IEEE Embedded Systems Letters the ACM Special Interest Group on Embedded Systems the ACM Special Interest Group on Design Automationt and the ACM Transactions on Embedded Computing Systems. Carlo S. Regazzoni (Senior Member IEEE) received the M.S. and Ph.D. degrees in electronic and telecommunications engineering from the University of Genoa Genoa Italy in 1987 and 1992 respectively.""He is currently a Full Professor of cognitive telecommunications systems with the Department of Electrical Electronics and Telecommunication Engineering and Naval Architecture (DITEN) University of Genoa and a Co-Ordinator of the Joint Doctorate on Interactive and Cognitive Environments (JDICE) international Ph.D. course started initially as EU Erasmus Mundus Project and

Autonomous systems are able to make decisions and potentially take actions without direct human intervention, which requires some knowledge about the system and its environment as well as goal-oriented reasoning. In computer systems, one can derive such behavior from the concept of a rational agent with autonomy (“control over its own actions”), reactivity (“react to events from the environment”), proactivity (“act on its own initiative”), and sociality (“interact with other agents”) as fundamental properties \n[1]\n. Autonomous systems will undoubtedly pervade into our everyday lives, and we will find them in a variety of domains and applications including robotics, transportation, health care, communications, and entertainment to name a few. \nThe articles in this month’s special issue cover concepts and fundamentals, architectures and techniques, and applications and case studies in the exciting area of self-awareness in autonomous systems.

关键词： Special issues and sections Autonomous systems Self-aware Robot sensing systems Computational modeling

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QUALITY MANAGEMENT ANd MASTER ORdNANCE REPAIR

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NAVAL ENGINEERS JOURNAL 1993年第5期105卷 68-76页

作者： STIMSON, WA MARTINEZ, E William A. Stimson:received his B.S. degree in mathematics from the University of Texas at El Paso in 1964 and his M.S. degree in engineering from the University of Santa Clara in 1971. Mr. Stimson was employed in the aerospace industry for ten years then joined the Naval Ship Weapon Systems Engineering Station in Port Hueneme Calif in 1973. At NSWSES he served ten years as a ship qualification trials project supervisor and seven years as program manager of the Master Ordnance Repair Program. Today Mr. Stimson lives in Charlottesville Va. and is a Ph.D candidate in systems engineering at the University of Virginia majoring in quality management and statistical quality control. Ernest Martinez:received his B.S. degree in computer sciences from National University in 1985. Mr. Martinez was head of combat systems at the Naval Ship Repair Facility Yokosuka Japan for five years returning in 1983 to the Naval Sea Support Center Pacific San Diego Calif. During the next five years he managed the Fleet Modernization Program and was coordinator of the Combat System Readiness Test Program. Today Mr. Martinez lives in San Diego and is employed by the Naval Surface Warfare Center Port Hueneme Calif. as MOR program manager.

Because of the redefinition of national defense needs and the reduction of defense budgets, the management of complex combatant repair is more imperative than ever. To this end, the U.S. Navy is calling for Total Quality Leadership (TQL) strategies from its agencies and contractors. These strategies are derived from well known initiatives of quality management, such as those of deming. They define the basis of any quality program. Quality methodologies have proven highly effective in the manufacturing sector, but many remain unproven or tentative in service and repair industries. The authors believe that TQL methods can be effective in the repair industry also, but must be developed or adapted to suit the unique characteristics of that industry: high skill, non-rote crafts, with continual customer interface at all levels of operation. In establishing a direction for TQL development, the authors have chosen two elements. The first is the Malcolm Baldrige Quality Improvement program, which provides guidelines for direction. The second is the Master Ordnance Repair (MOR) program, which provides the management vehicle. From its beginning in 1983, MOR has been a program of management. The task is explicit in its charter, NAVSEAINST 8000.2, which requires that a MOR contractor manage combat system work and testing. Quality management methods are applied to the MOR program to achieve MOR objectives using Baldrige measurements. Methods are presented which deploy the quality function across the organization. Techniques are provided to improve the company's ability to control its processes and the robustness of its product. These include methods of process analysis that determine added value, ownership, and internal customer. Stress is placed on in-process verification rather than on end-of-process inspection. The recommendations of this paper require no extraordinary skills or costs, but do require a formal and systematic approach to quality issues. The authors believe that

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Unveiling Multivariate EEG Features: A Novel Approach to Enhancing AdHd diagnosis Through Visual and Auditory Attention Tests

Unveiling Multivariate EEG Features: A Novel Approach to Enh...

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International Conference on Fuzzy Theory and it's Applications (iFUZZY)

作者： Zuo-Cian Fan Ro-Wei Lin Ching-Shu Tsai Wen-Jiun Chou Chia-Jung Li Zih-Jun Huang Bin-Yu Shih Liang-Jen Wang Li-Wei Ko Department of Biological Science & Technology Center for Intelligent Drug Systems and Smart Bio-Devices (IDS2B) College of Biological Science and Technology National Yang Ming Chiao Tung University Hsinchu Taiwan International Ph.D. Program in Interdisciplinary Neuroscience National Yang Ming Chiao Tung University Hsinchu Taiwan Department of Child and Adolescent Psychiatry Kaohsiung Chang Gung Memorial Hospit Department of Electronics and Electrical Engineering Institute of Electrical and Control Engineering National Yang Ming Chiao Tung University Hsinchu Taiwan

We sought to revolutionize the classification of Attention-deficit/Hyperactivity disorder (AdHd) by pioneering an innovative approach that seamlessly integrated auditory and visual tests with electroencephalogram (EEG) coherence analysis, forming the foundation for our Support Vector Machine (SVM) models. Our primary objective was to achieve precise differentiation between individuals with AdHd and those without, aiming to reshape the landscape of AdHd diagnosis and early intervention. We constructed an SVM model based on CATA coherence, incorporating a carefully selected set of 180 features, and another grounded in CPT coherence with 70 features. Astonishingly, our exploration uncovered that a model incorporating CATA's coherence and Power Spectral density (PSd) as features achieved an astounding accuracy rate of 97.7%, using only half the number of features. This revelation hints at untapped potential for multivariate advancements in the realm of AdHd classification. The landscape of AdHd diagnosis and intervention is perpetually evolving, most notably with the FdA's approval of game therapy for AdHd. Leveraging the transformative power of our findings, we envision the development of user-friendly game therapies for in-home use, empowering both clinicians and parents alike. This marks a paradigm shift in the realm of AdHd intervention, offering objective, data-driven tools for the early management of AdHd. Gamified therapy not only enhances accessibility but also fosters engagement and compliance, all of which are pivotal in the long-term care of individuals with AdHd. In summary, our study represents a significant advancement in our comprehension and classification of AdHd. By fusing auditory and visual tests with EEG coherence analysis, fortified by state-of-the-art machine learning techniques, we have achieved an unprecedented level of accuracy in identifying individuals with AdHd. Our findings, aligned with the FdA-approved game therapy, offer a glimpse into a

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