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PID control of data-driven patient response with fixed ratio co-administration of drugs for depth of hypnosis

IFAC-PapersOnLine 2024年第7期58卷 222-227页

作者： Clara M. Ionescu Hamed Farbakhsh Cristina Muresan Robin De Keyser Erhan Yumuk Ghada Ben Othman Amani Rayene Ynineb Isabela Birs Dana Copot Martine Neckebroek Ghent University Department of Electromechanics Systems and Metal Engineering Research Group on Dynamical Systems and Control Tech Lane Science Park 125 9052 Zwijnaarde Belgium Technical University of Cluj-Napoca Department of Automation Memorandumului no. 28 Cluj-Napoca 400114 Romania Istanbul Technical University Department of Control and Automation Engineering Systems and Control Istanbul Turkey Ghent University Hospital Department of Anesthesia C. Heymanslaan 10 9000 Ghent Belgium

In this work we make use of knowledge from clinical practice to deliver a trusted environment for feedback control of co-administration of two drugs to induce depth of hypnosis during general anesthesia. The clinical data we have provides valuable insight into the ratio used to determine the Propofol and Remifentanil infusion rates by means of specifying their corresponding effect site concentrations. A feedback closed loop with a fixed parameter PID controller tuned on population dynamics is used. To account the strong variations in gain of the system (patient) we propose an online identification of the dose-effect response from clinical data available during clinical protocol. Theoretical analysis is provided to justify the approach and simulations with real data from patient are given to support the theoretical insight. Limitations of this approach are discussed as to justify why ratio based co-administration is used in practice solely during the induction phase of general anesthesia.

关键词： Closed-Loop control of Anesthesia PID control Depth of Hypnosis Ratio control Model Estimation Data Driven control

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Accurate \mathcal{H}_{\infty}-Norm Estimation via Finite-Frequency Norms of Local Parametric Models

Accurate \mathcal{H}_{\infty}-Norm Estimation via Finite-Fre...

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2021 American control Conference, ACC 2021

作者： Tacx, Paul Oomen, Tom Control Systems Technology Group Eindhoven University of Technology Departement of Mechanical Engineering Eindhoven5600 Netherlands

ISBN: (纸本)9781665441971

\mathcal{H}_{\infty}-norm estimation is of critical importance for robust control design. This paper aims to develop an algorithm to estimate the \mathcal{H}_{\infty}-norm with a limited amount of data and limited user intervention. A frequency response-based approach is pursued, and local modeling techniques are exploited to include the inter-grid behavior. The main idea is to estimate the global \mathcal{H}_{\infty} norm by estimating the finite-frequency L8norm of the local models through the generalized KYP lemma. A simulation example shows the superiority of the proposed algorithm. © 2021 American Automatic control Council.

关键词： Frequency response

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Estimation of Metro Passenger Capacity Based on Passenger-Train Matching Model 3rd

Estimation of Metro Passenger Capacity Based on Passenger-Tr...

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3rd International Conference on Information control, Electrical engineering, and Rail Transit, ICEERT 2023

作者： Mei, Zhenkun Chen, Beijia Liu, Jiajun Shao, Jiayu Zhang, Ning Suzhou Rail Transit Group Co. Ltd. Jiangsu Suzhou215004 China School of Automation Southeast University Jiangsu Nanjing210096 China Key Laboratory of Measurement and Control of Complex Engineering Systems Ministry of Education Southeast University Jiangsu Nanjing210096 China ITS Engineering Research Center Ministry of Education Southeast University Jiangsu Nanjing211189 China

ISBN: (纸本)9789819788903

In the present scenario of the ‘one-tapin-one-tapout’ operation mode in urban rail transportation, determining passenger travel trajectories is challenging, thereby decreasing the effective counting of passengers on trains. In order to address this issue, a method for calculating passenger capacity on trains was developed by analyzing passenger travel information extracted from AFC data and train timetables. First, this research estimated the components of journey time to infer and reconstruct the passenger's specific spatiotemporal travel trajectory. The passenger-train matching model was then used to assign passengers to specific trains and calculate the passenger load of different trains at each station. At last, it took Suzhou Metro Line 3 as an example and analyzed the spatiotemporal distribution of urban rail transit passenger flow on a single line based on the proposed passenger-train model. © The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd. 2025.

关键词： Urban transportation

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Demonstrating Containerization of Model Predictive control for Modular Plants

Demonstrating Containerization of Model Predictive Control f...

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Industrial Cyber-Physical systems (ICPS)

作者： Lucas Vogt Zohra Charania Jonathan Mädler Julius Lorenz Helaleh Badrnoebashar Amy Koch Leon Urbas Process-to-Order Lab TU Dresden Dresden Germany Chair of Process Control Systems TU Dresden Dresden Germany Process Systems Engineering Group TU Dresden Dresden Germany

ISBN: (数字)9798350363012

ISBN: (纸本)9798350363029

Model predictive control has the potential to increase yields in the process industry, but its deployment is limited by high computational cost. In multi-purpose, modular plant concepts, it is particularly difficult to predict the whole variety of products for which a specific module will be used throughout its lifespan. During module manufacturing, this results in the challenge of allocating the correct computing, memory, and communication capacities to a module so that a model-predictive control application with currently unknown hardware requirements can be used later. The difficulty of this task often prevents the desirable deployment of model predictive control in production environments. The aim of this publication is therefore to demonstrate a simplified deployment and reconfiguration of model predictive control applications for modular plants through containerization. After an overview of the current state of the art, we present the underlying automation architecture based on modular plant concepts combined with a cloud-like automation approach enabled by containerization of the control applications. The feasibility of the chosen approach is demonstrated by implementing a proof-of-concept demonstrator. Subsequently, lessons learned from the demonstrator are discussed and future improvement potentials are identified, which will be the subject of future research.

关键词： Industries Automation Memory management Production Software Hardware Manufacturing

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Data-informativity conditions for structured linear systems with implications for dynamic networks

arXiv

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arXiv 2024年

作者： Van den Hof, Paul M.J. Shi, Shengling Fonken, Stefanie J.M. Ramaswamy, Karthik R. Hjalmarsson, Håkan Dankers, Arne G. Control Systems Group Department of Electrical Engineering Eindhoven University of Technology Netherlands Department of Chemical Engineering Massachusetts Institute of Technology United States ASML Veldhoven Netherlands Division of Decision and Control Systems Royal Institute of Technology Stockholm Sweden Department of Electrical and Software Engineering University of Calgary Canada

When estimating models of a multivariable dynamic system, a typical condition for consistency is to require the input signals to be persistently exciting, which is guaranteed if the input spectrum is positive definite for a sufficient number of frequencies. In this paper it is investigated how such a condition can be relaxed by exploiting prior structural information on the multivariable system, such as structural zero elements in the transfer matrix or entries that are a priori known and therefore not parametrized. It is shown that in particular situations the data-informativity condition can be decomposed into different MISO (multiple input single output) situations, leading to relaxed conditions for the MIMO (multiple input multiple output) model. When estimating a single module in a linear dynamic network, the data-informativity conditions can generically be formulated as path-based conditions on the graph of the network. The new relaxed conditions for data-informativity will then also lead to relaxed path-based conditions on the network graph. Additionally the new expressions are shown to be closely related to earlier derived conditions for (generic) single module identifiability. © 2024, CC BY-NC-ND.

关键词： MIMO systems

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Bidirectional EV charger integration into LV DC traction grid 17

Bidirectional EV charger integration into LV DC traction gri...

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17th IEEE International Conference on Compatibility, Power Electronics and Power engineering, CPE-POWERENG 2023

作者： Lukianov, Mykola Verbytskyi, Ievgen Cadaval, Enrique Romero Strzelecki, Ryszard Gdańsk University of Technology Faculty of Electrical and Control Engineering Gdańsk Poland National Technical University of Ukraine 'Igor Sikorsky Kyiv Polytechnic Institute' Dept. of Electronic Devices and Systems Kyiv Ukraine University of Extremadura Power Electrical and Electronic Systems R+D Group Badajoz Spain

ISBN: (纸本)9798350300048

Integration of bidirectional electric vehicle (EV) chargers into low voltage (LV) DC traction grids can potentially reduce chargers installation cost, as well as provide ancillary services for the DC grid, such as voltage stabilization, energy recuperation and reduced peak load. However, due to high LV DC grid voltage fluctuations and excessive load that EV chargers can create on a grid, their integration is challenging. In order to solve the problem, an EV charger connection scheme, converters parameters, as well as charger control algorithm must be considered wisely. This paper presents different connection solutions for bidirectional EV chargers integration into traction substations. A comparison of possible converter topologies that can be used in the system is made, depending on their efficiency, cost and applicability. Consequently, the system main parameters such as converters nominal power, voltage ratings and smart charging principle are presented. As a result, the proposed solution can be beneficial for developing EVs and public electric transport, which uses LV DC grids, such as trams/trolleybuses/metro. © 2023 IEEE.

关键词： Integration

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A Decoupled Fractional Order control Strategy to Increase Patient Safety During Anesthesia-Hemodynamic Interactions

A Decoupled Fractional Order Control Strategy to Increase Pa...

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European control Conference (ECC)

作者： Erwin Hegedus Marcian D. Mihai Isabela R. Birs Hamed Farbakhsh Erhan Yumuk Dana Copot Robain De Keyser Clara M. Ionescu Cristina I. Muresan Department of Automation Technical University of Cluj-Napoca Cluj-Napoca Romania Department of Electromechanics Ghent University Systems and Metal Engineering Research Group on Dynamical Systems and Control Tech Lane Zwijnaarde Belgium Department of Control and Automation Engineering Istanbul Technical University Istanbul Turkey

ISBN: (数字)9783907144107

ISBN: (纸本)9798331540920

Monitoring and control of general anesthesia, involving cardiac output or mean arterial pressure are critical to ensure patient safety during surgery. Several computer control solutions have been developed for each of the anesthesia components and hemodynamic processes. However, most do not tackle the synergistic and antagonistic effects of the anesthetic and hemodynamic drugs. Hitherto, only a handful of preliminary results and ideas regarding multivariable control have been reported so far, usually considering a simplified decentralized approach. A decoupled control strategy is proposed here to reduce the interaction between the hemodynamic and anesthesia sub-systems, hence increasing the robustness and stability of the overall control loop. Due to their intrinsic robustness to uncertainty and process model variability, fractional order controllers are designed to ensure that more specific performance criteria are addressed, compared to the traditional PIDs. The decoupled control strategy is compared to the decentralized approach to validate the minimization of the interactions. A robustness analysis is performed using a benchmark patient model and data from 24 patients.

关键词： Uncertainty Stability criteria Surgery Process control Anesthesia Robustness Hemodynamics

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Context-Aware control for Quality Improvement in Liquid Steel Manufacturing

Context-Aware Control for Quality Improvement in Liquid Stee...

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2023 IEEE Conference on control Technology and Applications, CCTA 2023

作者： Birs, Isabela R. Muresan, Cristina I. Susca, Mircea Mihaly, Vlad Mihai Ghita, Mihaela Ghita, Maria De Keyser, Robin Ionescu, Clara Eedt Decision & Control Flanders Make Consortium Tech Lane Science Park 125 and 131 GhentB-9052 Belgium Ghent University Research Group of Dynamical Systems and Control Faculty of Engineering and Architecture Belgium Technical University of Cluj Napoca Department of Automation Memorandumului nr 28 Cluj-Napoca400114 Romania

ISBN: (纸本)9798350335446

This paper presents an original theoretical and implementation framework of fractional order event-based control with the purpose of quality improvement at the end production line of a continuous casting process. A real-life steel manufacturing plant is taken into consideration in the study. A prior fractional order model is considered to tune a fractional order Proportional Integral controller that ensures an ideal flow velocity of liquid steel. A novel event-based fractional order methodology is proposed that uses internal and external process events in order to improve quality. The implementation strategy takes into consideration available software and hardware components at the plant site, offering a realistic and implementable solution, highly suitable for the current steel industry setting. Numeric simulations successfully validate the proposed methodology. © 2023 IEEE.

关键词： Steelmaking

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Modeling and Analysis of Bipedal Wheel-legged Robot with Sprawling Legs Mechanism

Modeling and Analysis of Bipedal Wheel-legged Robot with Spr...

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International Conference on Mechatronics (ICOM)

作者： Zulkifli Mansor Addie Irawan Nor Maniha Abdul Ghani Azrul Azim Abdullah Hashim Robotics Intelligent Systems & Control Engineering (RiSC) research group Faculty of Electrical & Electronics Engineering Technology Universiti Malaysia Pahang Al-Sultan Abdullah Pekan Pahang Malaysia

ISBN: (数字)9798350349788

ISBN: (纸本)9798350349795

This paper presents the modeling and analysis of the novel Bipedal Wheel-Legged Robot with Sprawling Legs Mechanism (BWLS) utilizing multi body dynamics approaches and the proposed Coxa-Based Coordinate System (CCS) in kinematics modeling. The primary focus lies in transitioning the conceptual model of the BWLS into the Simscape Multibody (SM) environment. The proposed CCS is subjected to verification through the implementation of a Hierarchical control Framework (HCF) utilizing a simple stand-up input trajectory. Through the analysis, initial angular positions and stable range angular joints are determined, revising previous determinations based on hardware structure. Furthermore, employing the Forward Kinematics (FK) model, the stable boundary is identified through spatial leg motion plots. The reliability of the proposed CCS kinematics model is affirmed, rendering the model ready for further in-depth studies and applications.

关键词： Legged locomotion Analytical models Mechatronics Robot kinematics Dynamics Kinematics Rendering (computer graphics)

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Coxa Coordination System-Based Hierarchical control Framework for Bipedal Wheel-Leg Robot with Sprawling Mechanism

Coxa Coordination System-Based Hierarchical Control Framewor...

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IEEE Conference on systems, Process & control (ICSPC)

作者： Zulkifli Mansor Addie Irawan Robotics Intelligent Systems & Control Engineering (RiSC) research group Faculty of Electrical & Electronics Engineering Technology Universiti Malaysia Pahang Al-Sultan Abdullah Pekan Pahang Malaysia

ISBN: (数字)9798350391398

ISBN: (纸本)9798350391404

The paper presents a Coxa Coordination System-Based Hierarchical control Framework (CCS-HCF) for a Bipedal Wheel-Leg Robot with a Sprawling Mechanism (BWLS), aimed at enhancing the flexibility navigation in rugged environments. The proposed method leverages the Coxa-Based Coordinate System (CCS) for optimizing leg motion and trajectory, facilitating stable and efficient locomotion across challenging terrains. The proposed method’s effectiveness is verified through various simulation works, highlighting the importance of specific parameter settings in the proposed CCSHCF, such as a Coxa angle for sprawling and mammalian postures, along with a swing height position. These configurations are crucial for maintaining stability and balance during operation. The findings demonstrate the bipedal wheel-legged robot such as BWLS system’s with the proposed CC-SHCF ready to be integrated by various stability and robust control layers for stable walking and skiing.

关键词： Legged locomotion Robust control Meters Navigation Robot kinematics Heuristic algorithms control systems Stability analysis Trajectory Optimization

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