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arXiv 2021年

作者： Holvitie, Johannes Licorish, Sherlock A. Spínola, Rodrigo O. Hyrynsalmi, Sami MacDonell, Stephen G. Mendes, Thiago S. Buchan, Jim Leppänen, Ville Turku Centre for Computer Science Software Development Laboratory Turku Finland University of Turku Department of Information Technology Turku Finland University of Otago Department of Information Science Otago Dunedin New Zealand Salvador University Graduate Program in Systems and Computer Bahia Salvador Brazil Federal University of Bahia Fraunhofer Project Center for Software and System Engineering Salvador Brazil Tampere University of Technology Pori Campus Pori Finland Federal Institute of Bahia Information Technology Department Bahia Santo Amaro Brazil Auckland University of Technology School of Engineering Computer and Mathematical Sciences Auckland New Zealand

Context: Contemporary software development is typically conducted in dynamic, resource-scarce environments that are prone to the accumulation of technical debt. While this general phenomenon is acknowledged, what remains unknown is how technical debt specifically manifests in and affects software processes, and how the software development techniques employed accommodate or mitigate the presence of this debt. Objectives: We sought to draw on practitioner insights and experiences in order to classify the effects of agile method use on technical debt management, given the popularity and perceived success of agile methods. We explore the breadth of practitioners' knowledge about technical debt;how technical debt is manifested across the software process;and the perceived effects of common agile software development practices and processes on technical debt. In doing so, we address a research gap in technical debt knowledge and provide novel and actionable managerial recommendations. Method: We designed, tested and executed a multi-national survey questionnaire to address our objectives, receiving 184 responses from practitioners in Brazil, Finland, and New Zealand. Results: Our findings indicate that: 1) Practitioners are aware of technical debt, although, there was under utilization of the concept, 2) Technical debt commonly resides in legacy systems, however, concrete instances of technical debt are hard to conceptualize which makes it problematic to manage, 3) Queried agile practices and processes help to reduce technical debt;in particular, techniques that verify and maintain the structure and clarity of implemented artifacts (e.g., Coding standards and Refactoring) positively affect technical debt management. Conclusions: The fact that technical debt instances tend to have characteristics in common means that a systematic approach to its management is feasible. However, notwithstanding the positive effects of some agile practices on technical debt management, comp

关键词： Legacy systems

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Towards long-tailed, multi-label disease classification from chest X-ray: Overview of the CXR-LT challenge

arXiv

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arXiv 2023年

作者： Holste, Gregory Zhou, Yiliang Wang, Song Jaiswal, Ajay Lin, Mingquan Zhuge, Sherry Yang, Yuzhe Kim, Dongkyun Nguyen-Mau, Trong-Hieu Tran, Minh-Triet Jeong, Jaehyup Park, Wongi Ryu, Jongbin Hong, Feng Verma, Arsh Yamagishi, Yosuke Kim, Changhyun Seo, Hyeryeong Kang, Myungjoo Celi, Leo Anthony Lu, Zhiyong Summers, Ronald M. Shih, George Wang, Zhangyang Peng, Yifan Department of Electrical and Computer Engineering The University of Texas at Austin AustinTX78712 United States Department of Population Health Sciences Weill Cornell Medicine New YorkNY10065 United States School of Information Systems Carnegie Mellon University PittsburghPA15213 United States Department of Electrical Engineering and Computer Science Massachussetts Institute of Technology CambridgeMA02139 United States School of Computer Science Carnegie Mellon University PittsburghPA15213 United States University of Science VNU-HCM Ho Chi Minh City70000 Viet Nam KT Research & Development Center KT Corporation Seoul06763 Korea Republic of Department of Software and Computer Engineering Ajou University Suwon16499 Korea Republic of Cooperative Medianet Innovation Center Shanghai Jiao Tong University Shanghai200240 China Wadhwani Institute for Artificial Intelligence Mumbai400079 India Division of Radiology and Biomedical Engineering Graduate School of Medicine The University of Tokyo Tokyo113-0033 Japan BioMedical AI Team AIX Future R&D Center SK Telecom Seoul04539 Korea Republic of Seoul National University Seoul02504 Korea Republic of Department of Mathematical Sciences Seoul National University Seoul02504 Korea Republic of Laboratory for Computational Physiology Massachusetts Institute of Technology CambridgeMA02139 United States Division of Pulmonary Critical Care and Sleep Medicine Beth Israel Deaconess Medical Center BostonMA02215 United States Department of Biostatistics Harvard T.H. Chan School of Public Health BostonMA02115 United States National Center for Biotechnology Information National Library of Medicine BethesdaMD20894 United States Clinical Center National Institutes of Health BethesdaMD20892 United States Department of Radiology Weill Cornell Medicine New YorkNY10065 United States

Many real-world image recognition problems, such as diagnostic medical imaging exams, are "long-tailed" – there are a few common findings followed by many more relatively rare conditions. In chest radiography, diagnosis is both a long-tailed and multi-label problem, as patients often present with multiple findings simultaneously. While researchers have begun to study the problem of long-tailed learning in medical image recognition, few have studied the interaction of label imbalance and label co-occurrence posed by long-tailed, multi-label disease classification. To engage with the research community on this emerging topic, we conducted an open challenge, CXR-LT, on long-tailed, multi-label thorax disease classification from chest X-rays (CXRs). We publicly release a large-scale benchmark dataset of over 350,000 CXRs, each labeled with at least one of 26 clinical findings following a long-tailed distribution. We synthesize common themes of top-performing solutions, providing practical recommendations for long-tailed, multi-label medical image classification. Finally, we use these insights to propose a path forward involving vision-language foundation models for few- and zero-shot disease classification. © 2023, CC BY-NC-SA.

关键词： Computer aided diagnosis

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Coherent H ∞ control for Markovian jump linear quantum systems

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IFAC-PapersOnLine 2020年第2期53卷 269-274页

作者： Yanan Liu Daoyi Dong Ian R. Petersen Qing Gao Steven X. Ding Hidehiro Yonezawa School of Engineering and Information Technology University of New South Wales Canberra ACT 2600 Australia Center for Quantum Computation and Communication Technology Australian Research Council Canberra ACT 2600 Australia Institute for Automatic Control and Complex Systems (AKS) University of Duisburg-Essen. 47057 Duisburg Germany Research School of Electrical Energy and Materials Engineering The Australian National University Canberra ACT 2601 Australia School of Automation Science and Electrical Engineering State Key Laboratory of Software Development Environment Beijing and also with Advanced Innovation Center for Big Data and Brain Computing Beihang University Beijing 100191 China

The purpose of this paper is to design a coherent feedback controller for a Markovian jump linear quantum system suffering from a fault signal. The control objective is to bound the effect of the disturbance input on the output for the time-varying quantum system. We prove the relation between the H ∞ control problem, the dissipation properties, and the solutions of Riccati differential equations, by which the H ∞ controller of the Markovian jump linear quantum system is given by the solutions of Linear Matrix Inequalities (LMIs).

关键词： Coherent quantum feedback H∞ control fault-tolerant control Markovian jump linear quantum systems

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Substrate concentration effect on gene expression in genetic circuits with additional positive feedback

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Science China(Technological Sciences) 2018年第8期61卷 1175-1183页

作者： WU LuLu WANG Pei Lü JinHu Academy of Mathematics and Systems Science Chinese Academy of Sciences School of Mathematical Sciences University of Chinese Academy of Sciences School of Mathematics and Statistics Henan University School of Automation Science and Electrical Engineering State Key Laboratory of Software Development Environment and Beijing Advanced Innovation Center for Big Data and Brain Machine Intelligence Beihang University

In gene regulatory networks, gene regulation loops often occur with multiple positive feedback, multiple negative feedback and coupled positive and negative feedback forms. In above gene regulation loops, auto-activation loops are ubiquitous regulatory motifs. This paper aims to investigate a two-component dual-positive feedback genetic circuit, which consists of a double negative feedback circuit and an additional positive feedback loop(APFL). We study effect of substrate concentration on gene expression in the single and the networked systems with APFLs, respectively. We find that substrate concentration can tune stochastic switch behavior in the signal system and then we explore relationship of substrate concentration with positive feedback strength in aspect of stochastic switch behavior. Furthermore, we also discuss gene expression and stochastic switch behavior in the networked systems with APFLs. Based on analysis in the networked systems, we discover that genes express in some specific cells and do not express in the other cells when the expression achieves its steady state. These results can be used to well explain the character of regionalization in the expression of genes and the phenomenon of gene differentiation.

关键词： substrate concentration additional positive feedback loop stochastic switch behavior gene expression gene differ-entiation

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Spatio-temporal propagation of COVID-19 pandemics

arXiv

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arXiv 2020年

作者： Gross, Bnaya Zheng, Zhiguo Liu, Shiyan Chen, Xiaoqi Sela, Alon Li, Jianxin Li, Daqing Havlin, Shlomo Department of Physics Bar-Ilan University Ramat-Gan52900 Israel School of Reliability and Systems Engineering Beihang University Beijing100191 China Department of Industrial Engineering Ariel University Ariel Israel Beijing Advanced Innovation Center for Big Data and Brain Computing Beihang University Beijing100083 China State Key Laboratory of Software Development Environment Beihang University Beijing100083 China Beijing Advanced Innovation Center for Big Data-Based Precision Medicine Beihang University Beijing100191 China

The new coronavirus known as COVID-19 is rapidly spreading since December 2019. Without any vaccination or medicine, the means of controlling it are limited to quarantine and social distancing. Here we study the spatio-temporal propagation of the COVID-19 virus in China and compare it to other global locations. Our results suggest that the disease propagation is highly related to population migration from Hubei resembling a Lévy flight which is characteristic of human mobility and thus could be controlled by efficient quarantines. Since quarantine is usually applied on a city level, more insight can be obtained in analyzing the epidemic in cities. Our results suggest that the disease spread in a city in China is characterized by two-stages process. At early times, at order of few days, the infection rate in the city is close to constant probably due to the lack of means to detect infected individuals before infection signs are observed and at later times it decays approximately exponentially due to quarantines. These two stages can explain the significant differences between the propagation in China and in other world-wide locations. While most cities in China control the disease which resulted in the decaying stage, in other world-wide countries the situation is still becoming worse probably due to less social interactions control and overloaded health systems which reflects in the death and recovery rates. Copyright © 2020, The Authors. All rights reserved.

关键词： Population dynamics

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Synchronization of Complex Dynamical Networks with Stochastic Coupling via PI Control

Synchronization of Complex Dynamical Networks with Stochasti...

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第三十八届中国控制会议

作者： Haibo Gu Kexin Liu Jinhu Lü Key Laboratory of Systems and Control Academy of Mathematics and Systems Science Chinese Academy of Sciences School of Mathematical Sciences University of Chinese Academy of Sciences School of Automation Science and Electrical Engineering State Key Laboratory of Software Development Environment and Beijing Advanced Innovation Center for Big Data and Brain Machine Intelligence Beihang University

With the development of sensor networks in the past two decades, synchronization of complex dynamical networks has received an increasing attention and has been widely studied both in theoretical research and in practical applications. This paper concerns the synchronization protocol design problem of nonlinear dynamical complex networks with stochastic ***-integral(PI) control protocols are designed to guarantee that complex dynamical networks with stochastic coupling can achieve global synchronization. Sufficient condition for choice of PI control gains are derived. Numerical example is included to demonstrate the efficiency of the theoretical results.

关键词： Synchronization Complex dynamical network Stochastic coupling PI control

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FUTURE-AI: International consensus guideline for trustworthy and deployable artificial intelligence in healthcare

arXiv

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arXiv 2023年

作者： Lekadir, Karim Feragen, Aasa Fofanah, Abdul Joseph Frangi, Alejandro F. Buyx, Alena Emelie, Anais Lara, Andrea Porras, Antonio R. Chan, An-Wen Navarro, Arcadi Glocker, Ben Botwe, Benard O. Khanal, Bishesh Beger, Brigit Wu, Carol C. Cintas, Celia Langlotz, Curtis P. Rueckert, Daniel Mzurikwao, Deogratias Fotiadis, Dimitrios I. Zhussupov, Doszhan Ferrante, Enzo Meijering, Erik Weicken, Eva González, Fabio A. Asselbergs, Folkert W. Prior, Fred Krestin, Gabriel P. Collins, Gary S. Tegenaw, Geletaw S. Kaissis, Georgios Misuraca, Gianluca Tsakou, Gianna Dwivedi, Girish Kondylakis, Haridimos Jayakody, Harsha Woodruf, Henry C. Mayer, Horst Joachim Aerts, Hugo JWL Walsh, Ian Chouvarda, Ioanna Buvat, Irène Tributsch, Isabell Rekik, Islem Duncan, James Kalpathy-Cramer, Jayashree Zahir, Jihad Park, Jinah Mongan, John Gichoya, Judy W. Schnabel, Julia A. Kushibar, Kaisar Riklund, Katrine Mori, Kensaku Marias, Kostas Amugongo, Lameck M. Fromont, Lauren A. Maier-Hein, Lena Alberich, Leonor Cerdá Rittner, Leticia Phiri, Lighton Marrakchi-Kacem, Linda Donoso-Bach, Lluís Martí-Bonmatí, Luis Cardoso, M. Jorge Bobowicz, Maciej Shabani, Mahsa Tsiknakis, Manolis Zuluaga, Maria A. Bielikova, Maria Fritzsche, Marie-Christine Camacho, Marina Linguraru, Marius George Wenzel, Markus De Bruijne, Marleen Tolsgaard, Martin G. Ghassemi, Marzyeh Ashrafuzzaman, Md Goisauf, Melanie Yaqub, Mohammad Abadía, Mónica Cano Mahmoud, Mukhtar M.E. Elattar, Mustafa Rieke, Nicola Papanikolaou, Nikolaos Lazrak, Noussair Díaz, Oliver Salvado, Olivier Pujol, Oriol Sall, Ousmane Guevara, Pamela Gordebeke, Peter Lambin, Philippe Brown, Pieta Abolmaesumi, Purang Dou, Qi Lu, Qinghua Osuala, Richard Nakasi, Rose Zhou, S. Kevin Napel, Sandy Colantonio, Sara Albarqouni, Shadi Joshi, Smriti Carter, Stacy Klein, Stefan Petersen, Steffen E. Aussó, Susanna Awate, Suyash Raviv, Tammy Riklin Cook, Tessa Mutsvangwa, Tinashe E.M. Rogers, Wendy A. Niessen, Wiro J. Puig-Bosch, Xènia Zeng, Yi Mohammed, Yunusa G. Aquino, Yves Saint James Salahuddin, Zohaib Starmans, Martijn P.A. Department de Matemàtiques i Informàtica Universitat de Barcelona Barcelona Spain Barcelona Spain DTU Compute Technical University of Denmark Kgs Lyngby Denmark Department of Mathematics and Computer Science Faculty of Science and Technology Milton Margai Technical University Freetown Sierra Leone Center for Computational Imaging & Simulation Technologies in Biomedicine Schools of Computing and Medicine University of Leeds Leeds United Kingdom Cardiovascular Science and Electronic Engineering Departments KU Leuven Leuven Belgium Institute of History and Ethics in Medicine Technical University of Munich Munich Germany Faculty of Engineering of Systems Informatics and Sciences of Computing Galileo University Guatemala City Guatemala Department of Biostatistics and Informatics Colorado School of Public Health University of Colorado Anschutz Medical Campus AuroraCO United States Department of Medicine Women’s College Research Institute University of Toronto Toronto Canada Universitat Pompeu Fabra BarcelonaBeta Brain Research Center Barcelona Spain Department of Computing Imperial College London London United Kingdom School of Biomedical & Allied Health Sciences University of Ghana Accra Ghana Department of Midwifery & Radiography School of Health & Psychological Sciences City University of London United Kingdom Kathmandu Nepal European Heart Network Brussels Belgium Department of Thoracic Imaging University of Texas MD Anderson Cancer Center Houston United States IBM Research Africa Nairobi Kenya Departments of Radiology Medicine and Biomedical Data Science Stanford University School of Medicine Stanford United States Institute for AI and Informatics in Medicine Klinikum rechts der Isar Technical University Munich Munich Germany Department of Computing Imperial College London London United Kingdom Muhimbili University of Health and Allied Sciences Dar es Salaam Tanzania United Republic of Ioannina Greece Almaty AI Lab Almaty Kazakhstan

Background: Despite major advances in artificial intelligence (AI) research for healthcare, the deployment and adoption of AI technologies remain limited in clinical practice. In recent years, concerns have been raised about the clinical, technical, ethical and legal risks associated with healthcare AI. To increase adoption in the real world, it is essential that AI technologies are trusted and accepted by patients, clinicians, health organisations and authorities. This paper describes the FUTURE-AI framework as the first international consensus guideline for trustworthy AI in healthcare. Methods: The FUTURE-AI consortium was founded in 2021 and now comprises 117 interdisciplinary experts from 50 countries representing all continents, including AI scientists, clinical researchers, biomedical ethicists, and social scientists. Over a two-year period, the consortium established guiding principles and best practices for trustworthy and deployable AI through an iterative process comprising an in-depth literature review, a modified Delphi survey, and online consensus meetings. Findings: The FUTURE-AI framework was established based on six guiding principles for trustworthy AI in healthcare, i.e. Fairness, Universality, Traceability, Usability, Robustness and Explainability. Through consensus, a set of 30 best practices were defined, addressing technical, clinical, socio-ethical and legal dimensions of trustworthy AI. The recommendations cover the entire lifecycle of healthcare AI, from design, development and validation to regulation, deployment, and monitoring. Interpretation: FUTURE-AI is a structured, risk-informed framework which provides guidance for constructing healthcare AI tools that will be trusted, deployed and adopted in real-world clinical practice. Researchers are encouraged to take the recommendations into account in proof-of-concept stages to facilitate future translation towards clinical practice of healthcare AI. Copyright © 2023, The Authors. All rights

关键词： Clinical research

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Global Pinning Synchronization with PI Controller in General Complex Directed Networks

Global Pinning Synchronization with PI Controller in General...

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第37届中国控制会议

作者： Peng Liu Haibo Gu Jinhu Lü Yu Kang Department of Automation University of Science and Technology of China LSC Academy of Mathematics and Systems ScienceChinese Academy of Sciences School of Mathematical Sciences University of Chinese Academy of Sciences School of Automation Science and Electrical Engineering State Key Laboratory of Software Development Environmentand Beijing Advanced Innovation Center for Big Data and Brain Machine IntelligenceBeihang University

Global pinning synchronization in complex networks has been extensively studied in the last decades due to its potential *** question is how to design an available controller to achieve global synchronization when the network is *** we all know,the classical PI controller is most widely and successfully used in engineering systems with nonlinear ***,the global synchronization with PI controller in general complex directed networks still remain *** this paper we will theoretically show that the global synchronization of some directed networks can also be ensured by designing an appropriate PI controller and pioneering some selected nodes,then a simple numerical example will also be given to verify our main results.

关键词： Directed network Pining synchronization PI controller Lyapunov method

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Distributed PI Control for Synchronization in Directed Strongly Connected Complex Dynamical Networks

Distributed PI Control for Synchronization in Directed Stron...

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第37届中国控制会议

作者： Haibo Gu Peng Liu Xiong Wang Jinhu L LSC Academy of Mathematics and Systems Science Chinese Academy of Sciences School of Mathematical Sciences University of Chinese Academy of Sciences Department of Automation University of Science and Technology of China School of Automation Science and Electrical Engineering State Key Laboratory of Software Development Environment and Beijing Advanced Innovation Center for Big Data and Brain Machine Intelligence Beihang University

Synchronization of directed complex networks has been extensively studied in the previous two decades due to its potential applications in the real world practices. To reveal and analyze the inherent mechanism of global synchronization in the complex networks with directed topologies, this paper attempts to developing a novel synchronization approach by using algebraic connectivity and PI control protocols. First, we studied the distributed PI control for synchronization in directed strongly connected networks and obtained some sufficient conditions to guarantee the networks reach global ***, a numerical example is given to verify the effectiveness of the proposed theoretical results.

关键词： Synchronization distributed PI control strongly connected network network control systems

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Random asynchronous iterations in distributed coordination algorithms

arXiv

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arXiv 2018年

作者： Chen, Yao Xia, Weiguo Cao, Ming Lü, Jinhu Department of Computer Science Southwestern University of Finance and Economics Chengdu611130 China School of Control Science and Engineering Dalian University of Technology Dalian116024 China Faculty of Science and Engineering ENTEG University of Groningen Groningen9747 AG Netherlands School of Automation Science and Electrical Engineering State Key Laboratory of Software Development Environment Beijing Advanced Innovation Center for Big Data and Brain Computing Beihang University Beijing100191 China Academy of Mathematics and Systems Science Chinese Academy of Sciences Beijing100190 China

Distributed coordination algorithms (DCA) carry out information processing processes among a group of networked agents without centralized information fusion. Though it is well known that DCA characterized by an SIA (stochastic, indecomposable, aperiodic) matrix generate consensus asymptotically via synchronous iterations, the dynamics of DCA with asynchronous iterations have not been studied extensively, especially when viewed as stochastic processes. This paper aims to show that for any given irreducible stochastic matrix, even non-SIA, the corresponding DCA lead to consensus successfully via random asynchronous iterations under a wide range of conditions on the transition probability. Particularly, the transition probability is neither required to be independent and identically distributed, nor characterized by a Markov chain. Copyright © 2018, The Authors. All rights reserved.

关键词： Stochastic systems

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