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检索条件"机构=Taiwan International Graduate Program in Bioinformatics"
58 条 记 录,以下是11-20 订阅
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Impact of DNA-binding position variants on yeast gene expression
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Nucleic Acids Research 2009年 第21期37卷 6991-7001页
作者: Swamy, Krishna B.S. Cho, Chung-Yi Chiang, Sufeng Tsai, Zing Tsung-Yeh Tsai, Huai-Kuang Institute of Information Science National Yang-Ming University Taiwan Bioinformatics Program Taiwan International Graduate Program National Yang-Ming University Taiwan Institute of Biomedical Informatics National Yang-Ming University Taiwan Research Center for Information Technology Innovation Academia Sinica Taipei 115 Taiwan
Transcription factors (TFs) regulate gene expression by binding to specific binding sites (TFBSs) in gene promoters. TFBS motifs may contain one or more variable positions. Although the prevailing assumption is that n...
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Predicting helix-helix interactions from residue contacts in membrane proteins
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bioinformatics 2009年 第8期25卷 996-1003页
作者: Lo, Allan Chiu, Yi-Yuan Rødland, Einar Andreas Lyu, Ping-Chiang Sung, Ting-Yi Hsu, Wen-Lian Bioinformatics Program Taiwan International Graduate Program Academia Sinica Taipei Taiwan Institute of Bioinformatics and Structural Biology Department of Life Sciences National Tsing Hua University Hsinchu Taiwan Bioinformatics Laboratory Institute of Information Science Academia Sinica Taipei Taiwan Centre for Cancer Biomedicine University of Oslo NO-0027 Oslo Norway SAMBA Norwegian Computing Center Blindern NO-0314 Oslo P.O. Box 114 Norway
Motivation: Helix-helix interactions play a critical role in the structure assembly, stability and function of membrane proteins. On the molecular level, the interactions are mediated by one or more residue contacts. ...
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Redesign of high-affinity nonspecific nucleases with altered sequence preference
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Journal of the American Chemical Society 2009年 第47期131卷 17345-17353页
作者: Wang, Yi-Ting Wright, Jon D. Doudeva, Lyudmila G. Jhang, Hua-Ci Lim, Carmay Yuan, Hanna S. Institute of Molecular Biology Academia Sinica Taipei Taiwan Institute of Biomedical Sciences Academia Sinica Taipei Taiwan Institute of Chemical Biology and Molecular Biophysics Taiwan International Graduate Program Academia Sinica Taipei Taiwan Institute of Bioinformatics and Structural Biology Department of Chemistry National Tsing Hua University HsinChu Taiwan Institute of Biochemistry and Molecular Biology National Taiwan University Taipei Taiwan
It is of crucial importance to elucidate the underlying principles that govern the binding affinity and selectivity between proteins and DNA. Here we use the nuclease domain of Colicin E7 (nColE7) as a model system to... 详细信息
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The keyword-based and semantic-driven data matching approach for assisting structuralizing the textual clinical documents
The keyword-based and semantic-driven data matching approach...
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international Conference on Biomedical Engineering and Informatics
作者: Chen, Chi-Huang Ping, Xiao-Ou Wang, Zi-Jun Hsieh, Sheau-Ling Chen, Li-Chin Tseng, Yi-Ju Hsu, Ching-Wei Lai, Feipei Department of Electrical Engineering National Taiwan University Taipei Taiwan Graduate Institute of Computer Science and Information Engineering National Taiwan University Taipei Taiwan Graduate Institute of Biomedical Electronic and Bioinformatics National Taiwan University Taipei Taiwan EECS International Graduate Program Institute/IT Center National Chiao Tung University Hsinchu Taiwan
The clinical data stored in the health information system can be categorized as two types including structuralized data and non-structuralized ones. In the paper, a data extraction system is developed to assist data r... 详细信息
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Enhanced expression of β3-galactosyltransferase 5 activity is sufficient to induce in vivo synthesis of extended type 1 chains on lactosylceramides of selected human colonic carcinoma cell lines
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Glycobiology 2009年 第4期19卷 418-427页
作者: Lin, Chi-Hung Fan, Yao-Yun Chen, Yen-Ying Wang, Shih-Hsin Chen, Chun-I Yu, Lung-Chih Khoo, Kay-Hooi Chemical Biology and Molecular Biophysics Program Taiwan International Graduate Program Academia Sinica Taipei 115 Taiwan Institute of Bioinformatics and Structural Biology National Tsing-Hua University Hsinchu 300 Taiwan Institute of Biological Chemistry Academia Sinica Nankang Taipei 115 Taiwan Taiwan and Institute of Biochemical Science National Taiwan University Taipei 106 Taiwan
In general, an elevated expression of β3-galactosyltrans-ferase (β3GalT) activity contributed by β3GalT5 correlates well with increased biosynthesis and expression of type 1 chain (Galβ1-3GlcNAcβ1-) derivatives s... 详细信息
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Chemical-Induced Disease Detection Using Invariance-based Pattern Learning Model  1
Chemical-Induced Disease Detection Using Invariance-based Pa...
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1st international Workshop on Digital Disease Detection using Social Media, DDDSM 2017, co-located with the 8th international Joint Conference on Natural Language Processing, IJCNLP 2017
作者: Warikoo, Neha Chang, Yung-Chun Hsu, Wen-Lian Institute of Biomedical Informatics National Yang-Ming University Taipei112 Taiwan Bioinformatics Program Taiwan International Graduate Program Institute of Information Science Academia Sinica Taipei115 Taiwan Institute of Information Science Academia Sinica Taipei115 Taiwan Graduate Institute of Data Science Taipei Medical University Taipei106 Taiwan
In this work, we introduce a novel feature engineering approach named "algebraic invariance" to identify discriminative patterns for learning relation pair features for the chemical-disease relation (CDR) ta... 详细信息
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Using a Recurrent Neural Network Model for Classification of Tweets Conveyed Influenza-related Information  1
Using a Recurrent Neural Network Model for Classification of...
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1st international Workshop on Digital Disease Detection using Social Media, DDDSM 2017, co-located with the 8th international Joint Conference on Natural Language Processing, IJCNLP 2017
作者: Wang, Chen-Kai Singh, Onkar Tang, Zhao-Li Dai, Hong-Jie Graduate Institute of Biomedical Informatics Taipei Medical University Taipei Taiwan Bioinformatics Program Taiwan International Graduate Program Institute of Information Science Academia Sinica Taipei Taiwan Institute of Biomedical Informatics National Yang-Ming University Taipei Taiwan Department of Computer Science and Information Engineering National Taitung University Taitung Taiwan Interdisciplinary Program of Green and Information Technology National Taitung University Taitung Taiwan
Traditional disease surveillance systems depend on outpatient reporting and virological test results released by hospitals. These data have valid and accurate information about emerging outbreaks but it's often no... 详细信息
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The largest genome-wide association study for breast cancer in taiwanese Han population
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Breast Cancer Research and Treatment 2024年 第2期203卷 291-306页
作者: Hsu, Yu-Ching Chen, Hung-Lin Cheng, Chi-Fung Chattopadhyay, Amrita Chen, Pei-Shan Lin, Che-Chen Chiang, Hsiu-Yin Liu, Ting-Yuan Huang, Chi-Hao Kuo, Chin-Chi Chuang, Eric Y. Lu, Tzu-Pin Tsai, Fuu-Jen Bioinformatics Program Taiwan International Graduate Program National Taiwan University Taipei Taiwan Bioinformatics Program Institute of Statistical Science Taiwan International Graduate Program Academia Sinica Taipei Taiwan Institute of Health Data Analytics and Statistics Department of Public Health College of Public Health National Taiwan University Taipei Taiwan Big Data Center China Medical University Hospital Taichung Taiwan Center for Translational Genomic Research Department of Medical Research China Medical University Hospital Taichung Taiwan Million-Person Precision Medicine Initiative Department of Medical Research China Medical University Hospital Taichung Taiwan Division of Breast Surgery Department of Surgery China Medical University Hospital Taichung Taiwan Division of Nephrology Department of Internal Medicine China Medical University Hospital Taichung Taiwan Department of Medical Research China Medical University Hospital Taichung Taiwan Bioinformatics and Biostatistics Core Center of Genomic and Precision Medicine National Taiwan University Taipei Taiwan Graduate Institute of Biomedical Electronics and Bioinformatics National Taiwan University Taipei Taiwan Biomedical Technology and Device Research Laboratories Industrial Technology Research Institute Hsinchu Taiwan Genetic Center Department of Medical Research China Medical University Hospital Taichung Taiwan
Purpose: Breast cancer is a molecularly heterogeneous disease, and multiple genetic variants contribute to its development and prognosis. Most of previous genome-wide association studies (GWASs) and polygenic risk sco... 详细信息
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Learning to predict expression efficacy of vectors in recombinant protein production
Learning to predict expression efficacy of vectors in recomb...
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8th Asia-Pacific bioinformatics Conference, APBC 2010
作者: Chan, Wen-Ching Liang, Po-Huang Shih, Yan-Ping Yang, Ueng-Cheng Lin, Wen-Chang Hsu, Chun-Nan Institute of Biomedical Informatics National Yang-Ming University Taipei Taiwan Bioinformatics Program Taiwan International Graduate Program Academia Sinica Taipei Taiwan Institute of Information Science Academia Sinica Taipei Taiwan Institute of Biological Chemistry Academia Sinica Taipei Taiwan Institute of Biomedical Sciences Academia Sinica Taipei Taiwan
Background: Recombinant protein production is a useful biotechnology to produce a large quantity of highly soluble proteins. Currently, the most widely used production system is to fuse a target protein into different... 详细信息
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Simultaneous identification for synergistic transcription factors and their transcription factor binding sites
Simultaneous identification for synergistic transcription fa...
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5th international Conference on Complex, Intelligent and Software Intensive Systems, CISIS 2011
作者: Tsai, Zing Tsung-Yeh Huang, Grace Tzu-Wei Tsai, Huai-Kuang Institute of Information Science Academia Sinica Taipei 115 Taiwan Bioinformatics Program Taiwan International Graduate Program Taiwan Institute of Biomedical Informatics National Yang-Ming University Taiwan Joint CMU-Pitt PhD Program in Computational Biology University of Pittsburgh Carnegie Mellon University Pittsburgh PA United States Research Center for Information Technology Innovation Taipei 115 Taiwan Computer Science and Engineering National Taiwan Ocean University Keelung 202 Taiwan
Identifying transcription factor binding sites (TFBSs) is crucial for understanding the mechanism of transcriptional regulation. It is known that transcription factors (TFs) often cooperate to regulate genes. While tr... 详细信息
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