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Educational Innovation (ECEI), IEEE Eurasian Conference on

作者： Chao-Kai Chang Chun-Yu Chiang Feng-Ming Yeh Chi-Hung Lee Chuen-Lin Tien der-Chin Chen Department of Optometry Yuanpei University of Medical Technology Hsinchu Taiwan Ph.D. Program of Electrical and Communications Engineering Feng Chia University Taichung Taiwan Department of Electrical Engineering Feng Chia University Taichung Taiwan

In this study, the human visual field test technology is established by using an optoelectrical system consisting of a translucent ellipsoid, an area light source, and a landscape scene with an indicator. during the test, the subjects stared at the indicator directly in front of them with one eye and kept their eyeballs still, scanning the light strip with peripheral vision and using the mouse button plus the playback program to record the start and end positions of the scanning light strip in the landscape scene. This method is tested subjectively, and the subject needs to respond during the test. Therefore, before the test, the subject needs to understand the test process and be trained in advance to improve the exam accuracy. In the experiment, fifteen subjects with normal vision and no eye disease were selected. Their visual fields were confirmed normal after a preliminary assessment. The test results showed that the subjects' eyes were within the normal visual field, indicating that this method was feasible. In this research, a digital optical platform for the near visual field is proposed to establish an optoelectric visual field measurement technology. The proposed method is characterized by small size, rapid operation, and easy portability. With the digital LCd and visual imaging technology, both dynamic and static visual fields can be tested. The test data on the eyes' upper, lower, nasal, and temporal sides were consistent with the normal visual field. This shows that this method is feasible and worthy of promotion in the optometry industry.

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Curricular Structure for Teaching Ethical and Professional Conduct in Optics and photonics

Curricular Structure for Teaching Ethical and Professional C...

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2021 Education and Training in Optics and photonics Conference, ETOP 2021

作者： Kuebler, Stephen M. Beever, Jonathan Pinkert, Laurie CREOL College of Optics and Photonics OrlandoFL32816 United States Chemistry Department OrlandoFL32816 United States Materials Science and Engineering Center for Ethics OrlandoFL32816 United States Department of Philosophy OrlandoFL32816 United States Texts and Technology Ph.D. Program OrlandoFL32816 United States

A full course focused on ethics and professional practice has been developed to complement technical coursework and provide comprehensive training for engineers studying optics. Related frameworks for ethical encultur... 详细信息

ISBN: (纸本)9781557528209

关键词： Personnel training

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Grinding wheel specification cybernetic recommendation with multi-task multi-imbalanced learning in smart manufacturing system

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Advanced Engineering Informatics 2024年 61卷

作者： Yao, Kuo-Ching Chen, Tzu-Li Chen, James C. Li, Chia-Ruei International Intercollegiate Ph.D. Program National Tsing Hua University Hsinchu30013 Taiwan Kinik Company New Taipei23942 Taiwan Graduate Institute of Intelligent Manufacturing Technology National Taiwan University of Science and Technology Taipei106335 Taiwan Department of Industrial Engineering and Engineering Management National Tsing Hua University Hsinchu300044 Taiwan

Over the years, the grinding wheels industry has played a crucial role in mechanical engineering. Grinding wheel specification is composed of various factors such as abrasive type, wheel grade, bond type, and more, which are derived from customer workpiece operation information. Traditionally, the determination process of grinding wheel specifications is complicated. Experienced engineers need to check out the limitation and consider the interaction of each factor. When the new specification order comes, engineers have to spend a lot of time on historical data search and discussion. Recently, the application of artificial intelligence attracts more and more attention in the manufacturing industry. Through collecting historical data, the model has the ability to extract the domain knowledge, predict the specification that does not exist, and reduce the decision time. However, when training the model, this grinding wheel specification faced multiple imbalanced targets and multi-task issues. In the past, research efforts primarily focused on studying single-task learning (STL) algorithms. Seldom of them has a systematic way to discuss the model determination of multiple targets and correlation influence, especially on the tabular-type dataset. In this study, we proposed a multiple resampling chain multi-task learning framework to address the issue of data science. To tackle the multi-task imbalance resampling problem, we also proposed a resampling strategy called Multiple Resampling Chain. Moreover, we conducted a sensitivity analysis to examine the correlation effect on model improvement. Finally, we proposed a cyber-recommendation system that integrates the training model and interface to provide a more intuitive way of specification prediction. This system not only can help engineers to improve the time spent on making decisions, but also make the whole manufacturing process to be more intelligent. © 2024 Elsevier Ltd

关键词： Grinding (machining)

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Improvement of catalytic activity of aluminum complexes for the ring-opening polymerization of ϵ-caprolactone: aluminum thioamidate and thioureidate systems

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dalton Transactions 2023年第46期52卷 17132-17147页

作者： Ganta, Prasanna Kumar Teja, Mallemadugula Ravi Chang, Chun-Juei Sambandam, Anandan Kamaraj, Rajiv Chu, Yu-Ting ding, Shangwu Chen, Hsing-Yin Chen, Hsuan-Ying Department of Medicinal and Applied Chemistry Drug Development and Value Creation Research Center Kaohsiung Medical University Kaohsiung80708 Taiwan Department of International Ph.D. Program for Science National Sun Yat-sen University Kaohsiung80424 Taiwan Nanomaterials and Solar Energy Conversion Lab Department of Chemistry National Institute of Technology Tiruchirappalli620015 India Department of Chemistry National Sun Yat-Sen University Kaohsiung80424 Taiwan Department of Medical Research Kaohsiung Medical University Hospital Kaohsiung80708 Taiwan National Pingtung University of Science and Technology Pingtung91201 Taiwan

In this study, a series of Al complexes bearing amidates, thioamidates, ureidates, and thioureidates were synthesized and their catalytic activity for ϵ-caprolactone (CL) polymerization was evaluated. SPr-Al exhibited a higher catalytic activity than OPr-Al (3.2 times as high for CL polymerization;[CL] : [SPr-Al] : [BnOH] = 100 : 0.5 : 2;[SPr-Al] = 10 mM, conv. = 93% after 14 min at 25 °C), and USCl-Al exhibited a higher catalytic activity than UCl-Al (4.6 times as high for CL polymerization;[CL] : [USCl-Al] : [BnOH] = 100 : 0.5 : 2;[USCl-Al] = 10 mM, conv. = 90% after 15 min at 25 °C). Regardless of whether aluminum amidates or ureidates were present, thioligands improved the polymerization rate of aluminum catalysts. density functional theory calculations revealed that the eight-membered ring [SPr-AlOMe2]2 decomposed into the four-membered ring SPr-AlOMe2. However, [OPr-AlOMe2]2 did not decompose because of its strong bridging Al-O bond. The overall activation energy required for CL polymerization was lower when using [SPr-AlOMe2]2 (18.1 kcal mol−1) as a catalyst than when using [OPr-AlOMe2]2 (23.9 kcal mol−1). This is because the TS2a transition state of SPr-AlOMe2 had a more open coordination geometry with a small N-Al-S angle (72.91°) than did TS3c of [OPr-AlOMe2]2, the crowded highest-energy transition state of [OPr-AlOMe2]2 with a larger N-Al-O angle (99.63°). © 2023 The Royal Society of Chemistry.

关键词： Synthesis (chemical)

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Humming-to-Instrument Conversion based on CycleGAN

Humming-to-Instrument Conversion based on CycleGAN

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2021 International Symposium on Intelligent Signal Processing and Communication Systems, ISPACS 2021

作者： Lai, Wen-Hsing Wang, Siou-Lin Xu, Zhi-Yao National Kaohsiung University of Science and Technology Dept. of Computer and Communication Engineering Kaohsiung Taiwan National Kaohsiung University of Science and Technology Ph.D. Program In Engineering Science and Technology College of Engineering Kaohsiung Taiwan

ISBN: (纸本)9781665419512

In this research, we propose a humming-to-instrument conversion system based on cycle-consistent adversarial networks (CycleGAN) to convert human humming to the sound of viola. This research adjusts the weight of cycle-consistency loss and identity loss to successfully convert the sound. From the experimental results of objective RMSE, the converted audio is more similar to viola compared to the similarity to humming. From the results of subjective MOS, the quality of the converted sound is fair to listeners. © 2021 IEEE.

关键词： Communication systems Signal processing

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ROBUST FEATURE LEARNING AGAINST NOISY LABELS

arXiv

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arXiv 2023年

作者： Tai, Tsung-Ming Jhang, Yun-Jie Hwang, Wen-Jyi Free University of Bozen-Bolzano Italy NVIDIA AI Technology Center Taiwan International Intercollegiate Ph.D. Program National Tsing Hua University Taiwan Department of Computer Science and Information Engineering National Taiwan Normal University Taiwan

Supervised learning of deep neural networks heavily relies on large-scale datasets annotated by high-quality labels. In contrast, mislabeled samples can significantly degrade the generalization of models and result in memorizing samples, further learning erroneous associations of data contents to incorrect annotations. To this end, this paper proposes an efficient approach to tackle noisy labels by learning robust feature representation based on unsupervised augmentation restoration and cluster regularization. In addition, progressive self-bootstrapping is introduced to minimize the negative impact of supervision from noisy labels. Our proposed design is generic and flexible in applying to existing classification architectures with minimal overheads. Experimental results show that our proposed method can efficiently and effectively enhance model robustness under severely noisy labels. Copyright © 2023, The Authors. All rights reserved.

关键词： Image classification

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Structure-Guided discovery of Pd-1/Pd-L1 Interaction Inhibitors: Peptide design, Screening, and Optimization via Computation-Aided phage display Engineering

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Journal of Chemical Information and Modeling 2024年第5期64卷 1615-1627页

作者： Tseng, Tien-Sheng Lee, Chao-Chang Chen, Po-Juei Lin, Chiu-Yuen Chen, Wang-Chuan Lee, Yu-Ching Lin, Jiun-Han Chen, Kaun-Wen Tsai, Keng-Chang Institute of Molecular Biology National Chung Hsing University Taichung40202 Taiwan National Research Institute of Chinese Medicine Ministry of Health and Welfare Taipei11221 Taiwan The School of Chinese Medicine for Post Baccalaureate I-Shou University Kaohsiung824005 Taiwan Department of Chinese Medicine E-Da Hospital Kaohsiung824005 Taiwan TMU Research Center of Cancer Translational Medicine Taipei Medical University Taipei11031 Taiwan Ph.D. Program in Medical Biotechnology College of Medical Science and Technology Taipei Medical University Taipei11031 Taiwan Department of Industrial Technology Ministry of Economic Affairs Taipei100210 Taiwan Food Industry Research and Development Institute Hsinchu30062 Taiwan Molecular Science and Digital Innovation Center Genetics Generation Advancement Corporation Taipei11949 Taiwan

Cancer immunotherapy harnesses the immune system to combat tumors and has emerged as a major cancer treatment modality. The Pd-1/Pd-L1 immune checkpoint modulates interactions between tumor cells and T cells and has been extensively targeted in cancer immunotherapy. However, the monoclonal antibodies known to target this immune checkpoint have considerable side effects, and novel Pd-1/Pd-L1 inhibitors are therefore required. Herein, a peptide inhibitor to disrupt Pd-1/Pd-L1 interactions was designed through structure-driven phage display engineering coupled to computational modification and optimization. BetaPb, a novel peptide library constructed by using the known structure of Pd-1/Pd-L, was used to develop inhibitors against the immune checkpoint, and specific peptides with high affinity toward Pd-1 were screened through enzyme-linked immunosorbent assays, homogeneous time-resolved fluorescence, and biolayer interferometry. A potential inhibitor, B8, was preliminarily screened through biopanning. The binding affinity of B8 toward Pd-1 was confirmed through computation-aided optimization. Assessment of B8 variants (B8.1, B8.2, B8.3, B8.4, and B8.5) demonstrated their attenuation of Pd-1/Pd-L1 interactions. B8.4 exhibited the strongest attenuation efficiency at a half-maximal effective concentration of 0.1 μM and the strongest binding affinity to Pd-1 (equilibrium dissociation constant = 0.1 μM). B8.4 outperformed the known Pd-1/Pd-L1 interaction inhibitor PL120131 in disrupting Pd-1/Pd-L1 interactions, revealing that B8.4 has remarkable potential for modification to yield an antitumor agent. This study provides valuable information for the future development of peptide-based drugs, therapeutics, and immunotherapies for cancer. © 2024 American Chemical Society.

关键词： Peptides

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What affects users to click social media ads and purchase intention? The roles of advertising value, emotional appeal and credibility

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Asia Pacific Journal of Marketing and Logistics 2022年第8期35卷 1900-1916页

作者： Wen-Kuo Chen Chia-Ju Ling Chien-Wen Chen Department of Money and Banking National Kaohsiung University of Science and Technology Kaohsiung Taiwan Ph.D. Program in Management Dayeh University Changhua Taiwan Department of Business Administration Feng Chia University College of Business Taichung Taiwan

Purpose This study is based on a web-based advertising value model, adding emotional appeal, advertising credibility, advertising clicks, product evaluation and incentive to examine the impact on consumers' product evaluation and purchase intention. design/methodology/approach In total, 313 valid online questionnaires were collected from those who had browsed the social media advertisement. Findings The results show that advertising credibility and emotional appeal have a higher impact on advertising attitude than informativeness and irritation in the original web-based advertising value model. Research limitations/implications The findings strengthen the literature on the antecedents of advertising attitude in social media context, confirming advertising clicks as a predictor of product evaluation, and determining that advertising attitude, product evaluation and incentive play key roles as predictors of consumer purchase intention. Practical implications The findings are particularly relevant to advertising marketing managers. In the context of social media advertising, the advertising credibility of consumers is the key to increasing consumers' willingness to purchase. Advertisers must establish a good advertising reputation to consumers in the social media context. Originality/value This study combines the web-based advertising value model, advertising clicks, product evaluation and incentive to investigate the factors that influence customers' purchase decisions in the context of social media.

关键词： Advertising value model Ad clicks Product evaluation Incentive Purchase intention

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Analysis on Predictive Water Temperature with PId Controller and SCAdA System

Analysis on Predictive Water Temperature with PID Controller...

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2021 International Symposium on Intelligent Signal Processing and Communication Systems, ISPACS 2021

作者： Tu, Wen-Fu Wang, Yi-Shun Chen, Tu-Sheng National Kaohsiung University of Science and Technology Marit Mechatronics Engineering Lab Department of Marine Engineering Kaohsiung Taiwan National Kaohsiung University of Science and Technology Ph.D. Program In Maritime Science and Technology College of Maritime Kaohsiung Taiwan

ISBN: (纸本)9781665419512

Marine diesel engine start-up goes through the following speed stages: dead slow, slow, half, and full. The jacket water should be heated initially to prevent the cylinder from cracking due to excessive temperature difference. In this paper, PId temperature controller and SCAdA system are used to heat the jacket water. Experimental tests have been evaluated to improve closed loop response with PId temperature controller and SCAdA system. The heating mode calls the appropriate PId controller according to the design temperature to compare the actual temperature at different stages. The experimental results show that the PId controller converges the temperature well between 35and 80, the optimal PId parameter are P=3, I=198, d=495 with the auto tune function and the max. power supply current I=8.8A, voltage V=110V. © 2021 IEEE.

关键词： Three term control systems

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Color Refractive Error Exam for Speech disorder

Color Refractive Error Exam for Speech Disorder

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2022 International Symposium on Intelligent Signal Processing and Communication Systems, ISPACS 2022

作者： Yeh, Feng-Ming Huang, Liang-Ying Chiang, Chun-Yu Chang, Rong-Seng Tien, Chuen-Lin Hsieh, Ya-Hui Chen, der-Chin Yuanpei University of Medical Technology Department of Optometry Hsinchu Taiwan National Central University Department of Optics and Photonics Taoyuan Taiwan Feng Chia University Ph.D. Program of Electrical and Communications Engineering Taichung Taiwan Feng Chia University Department of Electrical Engineering Taichung Taiwan Ming Chuan University Department of Healthcare Information and Management Taoyuan Taiwan

ISBN: (纸本)9798350332421

In this study, a micro-led display, an eye chart player software, and image capture and processing module were used to construct a color refractive error exam for subject with speech disorder. This method can be used to test subjects with refractive errors, eye's color vision and other pathological problems. The micro-led display uses an eye chart player program to display the capital letters E and the other fonts, and the gaps of the E letters can be tumbled in any direction. When subjects with speech disorder were examined for vision, the E chart was displayed sequentially from big letters to small letters, and the image capture and processing module was synchronized with the eye chart player program. The subjects only need to point out the direction of the gap with gestures, and the image capture and processing module can simultaneously capture the gestures of the subjects to judge visual test status. In this study, twenty subjects were tested and all obtained the correct VA value and wore excellent eye glasses. The characteristic of this innovative method is that the subjects with a speech disorder can use simple hand gestures to complete the visual exam through the image capture and processing module during the inspection. © 2022 IEEE.

关键词： Color

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