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arXiv 2019年

作者： Wan, Jun Lin, Chi Wen, Longyin Li, Yunan Miao, Qiguang Escalera, Sergio Anbarjafari, Gholamreza Guyon, Isabelle Guo, Guodong Li, Stan Z. National Laboratory of Pattern Recognition Institute of Automation Chinese Academy of Sciences Beijing100190 China JD Finance Mountain ViewCA United States University of Southern California Los AngelesCA90089-0911 United States School of Computer Science and Technology Xidian University & Xi'an Key Laboratory of Big Data and Intelligent Vision 2nd South Taibai Road Xi'an710071 China Universitat de Barcelona Computer Vision Center Spain iCV Lab Institute of Technology University of Tartu Estonia Faculty of Engineering Hasan Kalyoncu University Gaziantep Turkey Institute of Digital Technologies Loughborough University London United Kingdom ChaLearn United States University Paris-Saclay France institute of Deep Learning Baidu Research National Engineering Laboratory for Deep Learning Technology and Application China

The ChaLearn large-scale gesture recognition challenge has been run twice in two workshops in conjunction with the International Conference on pattern recognition (ICPR) 2016 and International Conference on computer vision (ICCV) 2017, attracting more than 200 teams around the world. This challenge has two tracks, focusing on isolated and continuous gesture recognition, respectively. This paper describes the creation of both benchmark datasets and analyzes the advances in large-scale gesture recognition based on these two datasets. We discuss the challenges of collecting large-scale ground-truth annotations of gesture recognition, and provide a detailed analysis of the current state-of-the-art methods for large-scale isolated and continuous gesture recognition based on RGB-D video sequences. In addition to recognition rate and mean jaccard index (MJI) as evaluation metrics used in our previous challenges, we also introduce the corrected segmentation rate (CSR) metric to evaluate the performance of temporal segmentation for continuous gesture recognition. Furthermore, we propose a bidirectional long short-term memory (Bi-LSTM) baseline method, determining the video division points based on the skeleton points extracted by convolutional pose machine (CPM). Experiments demonstrate that the proposed Bi-LSTM outperforms the state-of-the-art methods with an absolute improvement of 8.1% (from 0.8917 to 0.9639) of CSR. Copyright © 2019, The Authors. All rights reserved.

关键词： Long short-term memory

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Clustering-based Discriminative Locality Alignment for Face Gender recognition

Clustering-based Discriminative Locality Alignment for Face ...

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IEEE/RSJ International Conference on Intelligent Robotics and Systems

作者： Duo Chen Jun Cheng Dacheng Tao College of Communication Engineering Chongqing University Chongqing 400044 China. He is also with the Shenzhen Key Laboratory of Computer Vision and Pattern Recognition Shenzhen Institutes of Advanced Technology Chinese Academy of Sciences. Shenzhen Institutes of Advanced Technology Chinese Academy of Sciences Shenzhen 518055 China. He is also with the Chinese University of Hong Kong and Guangdong Provincial Key Laboratory of Robotics and Intelligent System. Center for Quantum Computation and Intelligent System Faculty of Engineering and Information Technology University of Technology Sydney New South Wales 2007 Australia.

ISBN: (数字)9781467317368

ISBN: (纸本)9781467317375

To facilitate human-robot interactions, human gender information is very important. Motivated by the success of manifold learning for visual recognition, we present a novel clustering-based discriminative locality alignment (CDLA) algorithm to discover the low-dimensional intrinsic submanifold from the embedding high-dimensional ambient space for improving the face gender recognition performance. In particular, CDLA exploits the global geometry through k-means clustering, extracts the discriminative information through margin maximization and explores the local geometry through intra cluster sample concentration. These three properties uniquely characterize CDLA for face gender recognition. The experimental results obtained from the FERET data sets suggest the superiority of the proposed method in terms of recognition speed and accuracy by comparing with several representative methods.

关键词： FERET CDLA comparing recognition (Psychology) Gender Global geometry Compare Face Face

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Towards Phytoplankton Parasite Detection Using Autoencoders

arXiv

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arXiv 2023年

作者： Bilik, Simon Batrakhanov, Daniel Eerola, Tuomas Haraguchi, Lumi Kraft, Kaisa Van den Wyngaert, Silke Kangas, Jonna Sjöqvist, Conny Madsen, Karin Lensu, Lasse Kälviäinen, Heikki Horak, Karel Computer Vision and Pattern Recognition Laboratory Department of Computational Engineering Lappeenranta-Lahti University of Technology LUT Yliopistonkatu 34 Lappeenranta53850 Finland Department of Control and Instrumentation Faculty of Electrical Engineering and Communication Brno University of Technology Technická 3058/10 Brno61600 Czech Republic Marine Ecology Measurements Finnish Environment Institute Agnes Sjöbergin Katu 2 Helsinki00790 Finland Department of Biology University of Turku Vesilinnantie 5 Turku20014 Finland Environmental and Marine Biology Åbo Akademi University Henrikinkatu 2 Turku20014 Finland

Phytoplankton parasites are largely understudied microbial components with a potentially significant ecological impact on phytoplankton bloom dynamics. To better understand their impact, we need improved detection methods to integrate phytoplankton parasite interactions in monitoring aquatic ecosystems. Automated imaging devices usually produce high amount of phytoplankton image data, while the occurrence of anomalous phytoplankton data is rare. Thus, we propose an unsupervised anomaly detection system based on the similarity of the original and autoencoder-reconstructed samples. With this approach, we were able to reach an overall F1 score of 0.75 in nine phytoplankton species, which could be further improved by species-specific fine-tuning. The proposed unsupervised approach was further compared with the supervised Faster R-CNN based object detector. With this supervised approach and the model trained on plankton species and anomalies, we were able to reach the highest F1 score of 0.86. However, the unsupervised approach is expected to be more universal as it can detect also unknown anomalies and it does not require any annotated anomalous data that may not be always available in sufficient quantities. Although other studies have dealt with plankton anomaly detection in terms of non-plankton particles, or air bubble detection, our paper is according to our best knowledge the first one which focuses on automated anomaly detection considering putative phytoplankton parasites or infections. © 2023, CC BY.

关键词： Object detection

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Group shift pointwise convolution for volumetric medical image segmentation

arXiv

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arXiv 2021年

作者： He, Junjun Ye, Jin Li, Cheng Song, Diping Chen, Wanli Wang, Shanshan Gu, Lixu Qiao, Yu School of Biomedical Engineering Shanghai Jiao Tong University Shanghai China Institute of Medical Robotics Shanghai Jiao Tong University Shanghai China Shenzhen Key Lab of Computer Vision and Pattern Recognition SIAT-SenseTime Joint Lab Shenzhen Institute of Advanced Technology Chinese Academy of Sciences Guangdong Shenzhen China Shanghai AI Lab Shanghai China Paul C. Lauterbur Research Center for Biomedical Imaging Shenzhen Institute of Advanced Technology Chinese Academy of Sciences Guangdong Shenzhen China The Chinese University of Hong Kong Hong Kong Peng Cheng Laboratory Guangdong Shenzhen China Pazhou Lab Guangdong Guangzhou China

Recent studies have witnessed the effectiveness of 3D convolutions on segmenting volumetric medical images. Compared with the 2D counterparts, 3D convolutions can capture the spatial context in three dimensions. Nevertheless, models employing 3D convolutions introduce more trainable parameters and are more computationally complex, which may lead easily to model overfitting especially for medical applications with limited available training data. This paper aims to improve the effectiveness and efficiency of 3D convolutions by introducing a novel Group Shift Pointwise Convolution (GSP-Conv). GSP-Conv simplifies 3D convolutions into pointwise ones with 1 × 1 × 1 kernels, which dramatically reduces the number of model parameters and FLOPs (e.g. 27× fewer than 3D convolutions with 3 × 3 × 3 kernels). Naïve pointwise convolutions with limited receptive fields cannot make full use of the spatial image context. To address this problem, we propose a parameter-free operation, Group Shift (GS), which shifts the feature maps along different spatial directions in an elegant way. With GS, pointwise convolutions can access features from different spatial locations, and the limited receptive fields of pointwise convolutions can be compensated. We evaluate the proposed methods on two datasets, PROMISE12 and BraTS18. Results show that our method, with substantially decreased model complexity, achieves comparable or even better performance than models employing 3D convolutions. Copyright © 2021, The Authors. All rights reserved.

关键词： Convolution

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Multi-View Partial (MVP) Point Cloud Challenge 2021 on Completion and Registration: Methods and Results

arXiv

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arXiv 2021年

作者： Pan, Liang Wu, Tong Cai, Zhongang Liu, Ziwei Yu, Xumin Rao, Yongming Lu, Jiwen Zhou, Jie Xu, Mingye Luo, Xiaoyuan Fu, Kexue Gao, Peng Wang, Manning Wang, Yali Qiao, Yu Zhou, Junsheng Wen, Xin Xiang, Peng Liu, Yu-Shen Han, Zhizhong Yan, Yuanjie An, Junyi Zhu, Lifa Lin, Changwei Liu, Dongrui Li, Xin Gómez-Fernández, Francisco Wang, Qinlong Yang, Yang S-Lab Nanyang Technological University Singapore SenseTime-CUHK Joint Lab The Chinese University of Hong Kong Hong Kong Sensetime Research Shanghai AI Laboratory China Department of Automation Tsinghua University China University of Chinese Academy of Sciences China ShenZhen Key Lab of Computer Vision and Pattern Recognition SIAT-SenseTime Joint Lab Shenzhen Institutes of Advanced Technology Chinese Academy of Sciences China Digital Medical Research Center School of Basic Medical Science Fudan University China School of Software BNRist Tsinghua University China *** Wayne State University State Key Laboratory for Novel Software Technology Nanjing University China DeepGlint Shanghai Jiao Tong University China Sichuan University China Xi'an Jiaotong University China

As real-scanned point clouds are mostly partial due to occlusions and viewpoints, reconstructing complete 3D shapes based on incomplete observations becomes a fundamental problem for computer vision. With a single incomplete point cloud, it becomes the partial point cloud completion problem. Given multiple different observations, 3D reconstruction can be addressed by performing partial-to-partial point cloud registration. Recently, a large-scale Multi-View Partial (MVP) point cloud dataset has been released, which consists of over 100,000 high-quality virtual-scanned partial point clouds. Based on the MVP dataset, this paper reports methods and results in the Multi-View Partial Point Cloud Challenge 2021 on Completion and Registration. In total, 128 participants registered for the competition, and 31 teams made valid submissions. The top-ranked solutions will be analyzed, and then we will discuss future research directions. Copyright © 2021, The Authors. All rights reserved.

关键词： Surface measurement

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Corrigendum to Intrusion detection based on improved density peak clustering for imbalanced data on sensor-cloud systems Journal of Systems Architecture volume 118 (2021) 102212

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Journal of Systems Architecture 2021年 119卷

作者： Ming Yan Yewang Chen Xiaoliang Hu Dongdong Cheng Yi Chen Jixiang Du The College of Computer Science and Technology Huaqiao University Xiamen China Beijing Key Laboratory of Big Data Technology for Food Safety Beijing Technology and Business University Beijing China Provincial Key Laboratory for Computer Information Processing Technology Soochow University Soochow China Xiamen Key Laboratory of Computer Vision and Pattern Recognition Huaqiao University Fujian Key Laboratory of Big Data Intelligence and Security Huaqiao University Xiamen China College of Big Data and Intelligent Engineering Yangtze Normal University Chongqing China

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A novel hybrid convolutional neural network for accurate organ segmentation in 3d head and neck CT images

arXiv

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arXiv 2021年

作者： Chen, Zijie Li, Cheng He, Junjun Ye, Jin Song, Diping Wang, Shanshan Gu, Lixu Qiao, Yu Shenzhen Key Lab of Computer Vision and Pattern Recognition SIAT-SenseTime Joint Lab Shenzhen Institute of Advanced Technology Chinese Academy of Sciences Guangdong Shenzhen China Shanghai AI Lab Shanghai China Shenzhen Yino Intelligence Techonology Co. Ltd. Guangdong Shenzhen China Co. Ltd. Guangdong Shenzhen China Paul C. Lauterbur Research Center for Biomedical Imaging Shenzhen Institute of Advanced Technology Chinese Academy of Sciences Guangdong Shenzhen China School of Biomedical Engineering Shanghai Jiao Tong University Shanghai China Institute of Medical Robotics Shanghai Jiao Tong University Shanghai China Peng Cheng Laboratory Guangdong Shenzhen China Pazhou Lab Guangdong Guangzhou China

Radiation therapy (RT) is widely employed in the clinic for the treatment of head and neck (HaN) cancers. An essential step of RT planning is the accurate segmentation of various organs-at-risks (OARs) in HaN CT images. Nevertheless, segmenting OARs manually is time-consuming, tedious, and error-prone considering that typical HaN CT images contain tens to hundreds of slices. Automated segmentation algorithms are urgently required. Recently, convolutional neural networks (CNNs) have been extensively investigated on this task. Particularly, 3D CNNs are frequently adopted to process 3D HaN CT images. There are two issues with naïve 3D CNNs. First, the depth resolution of 3D CT images is usually several times lower than the in-plane resolution. Direct employment of 3D CNNs without distinguishing this difference can lead to the extraction of distorted image features and influence the final segmentation performance. Second, a severe class imbalance problem exists, and large organs can be orders of times larger than small organs. It is difficult to simultaneously achieve accurate segmentation for all the organs. To address these issues, we propose a novel hybrid CNN that fuses 2D and 3D convolutions to combat the different spatial resolutions and extract effective edge and semantic features from 3D HaN CT images. To accommodate large and small organs, our final model, named Organ-Net2.5D, consists of only two instead of the classic four downsampling operations, and hybrid dilated convolutions are introduced to maintain the respective field. Experiments on the MICCAI 2015 challenge dataset demonstrate that OrganNet2.5D achieves promising performance compared to state-of-the-art methods. Copyright © 2021, The Authors. All rights reserved.

关键词： Convolution

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REFUGE2 CHALLENGE: A TREASURE TROVE FOR MULTI-DIMENSION ANALYSIS AND EVALUATION IN GLAUCOMA SCREENING

arXiv

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arXiv 2022年

作者： Fang, Huihui Li, Fei Wu, Junde Fu, Huazhu Sun, Xu Son, Jaemin Yu, Shuang Zhang, Menglu Yuan, Chenglang Bian, Cheng Lei, Baiying Zhao, Benjian Xu, Xinxing Li, Shaohua Fumero, Francisco Sigut, José Almubarak, Haidar Bazi, Yakoub Guo, Yuanhao Zhou, Yating Baid, Ujjwal Innani, Shubham Guo, Tianjiao Yang, Jie Orlando, José Ignacio Bogunović, Hrvoje Zhang, Xiulan Xu, Yanwu The REFUGE2 Challenge Australia State Key Laboratory of Ophthalmology Zhongshan Ophthalmic Center Sun Yat-Sen University Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science Guangzhou China Intelligent Healthcare Unit Baidu Inc. Beijing China The Institute of High Performance Computing Agency for Science Technology and Research Singapore Yatiris Group PLADEMA Institute CONICET UNICEN Tandil Argentina Christian Doppler Lab for Artificial Intelligence in Retina Department of Ophthalmology and Optometry Medical University of Vienna Vienna Austria VUNO Inc Seoul Korea Republic of Tencent HealthCare Tencent Shenzhen China Computer Vision Institute College of Computer Science and Software Engineering of Shenzhen University Shenzhen China School of Biomedical Engineering Health Science Center Shenzhen University China Xiaohe Healthcare ByteDance Guangdong Guangzhou510000 China School of Biomedical Engineering Shenzhen University China College of Computer Science & Software Engineering Shenzhen University China Department of Computer Science and Systems Engineering Universidad de La Laguna Spain Saudi Electronic University Saudi Arabia King Saud University Saudi Arabia Institute of Automation Chinese Academy of Sciences Beijing China University of Chinese Academy of Sciences Beijing China SGGS Institute of Engineering and Technology India Institute of Medical Robotics Shanghai Jiao Tong University China Institute of Image Processing and Pattern Recognition Shanghai Jiao Tong University China

With the rapid development of artificial intelligence (AI) in medical image processing, deep learning in color fundus photography (CFP) analysis is also evolving. Although there are some open-source, labeled datasets of CFPs in the ophthalmology community, large-scale datasets for screening only have labels of disease categories, and datasets with annotations of fundus structures are usually small in size. In addition, labeling standards are not uniform across datasets, and there is no clear information on the acquisition device. Here we release a multi-annotation, multi-quality, and multi-device color fundus image dataset for glaucoma analysis on an original challenge-Retinal Fundus Glaucoma Challenge 2nd Edition (REFUGE2). The REFUGE2 dataset contains 2000 color fundus images with annotations of glaucoma classification, optic disc/cup segmentation, as well as fovea localization. Meanwhile, the REFUGE2 challenge sets three sub-tasks of automatic glaucoma diagnosis and fundus structure analysis and provides an online evaluation framework. Based on the characteristics of multi-device and multi-quality data, some methods with strong generalizations are provided in the challenge to make the predictions more robust. This shows that REFUGE2 brings attention to the characteristics of real-world multi-domain data, bridging the gap between scientific research and clinical application. © 2022, CC BY-NC-ND.

关键词： Color

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Author Correction: Development and clinical deployment of a smartphone-based visual field deep learning system for glaucoma detection

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NPJ digital medicine 2022年第1期5卷 38页

作者： Fei Li Diping Song Han Chen Jian Xiong Xingyi Li Hua Zhong Guangxian Tang Sujie Fan Dennis S C Lam Weihua Pan Yajuan Zheng Ying Li Guoxiang Qu Junjun He Zhe Wang Ling Jin Rouxi Zhou Yunhe Song Yi Sun Weijing Cheng Chunman Yang Yazhi Fan Yingjie Li Hengli Zhang Ye Yuan Yang Xu Yunfan Xiong Lingfei Jin Aiguo Lv Lingzhi Niu Yuhong Liu Shaoli Li Jiani Zhang Linda M Zangwill Alejandro F Frangi Tin Aung Ching-Yu Cheng Yu Qiao Xiulan Zhang Daniel S W Ting State Key Laboratory of Ophthalmology Zhongshan Ophthalmic Center Sun Yat-Sen University Guangzhou People's Republic of China. ShenZhen Key Lab of Computer Vision and Pattern Recognition Shenzhen Institutes of Advanced Technology The Chinese Academy of Sciences Shenzhen People's Republic of China. University of Chinese Academy of Sciences Beijing People's Republic of China. Department of Ophthalmology The First Affiliated Hospital of Kunming Medical University Kunming People's Republic of China. The First Hospital of Shijiazhuang City Shijiazhuang People's Republic of China. gxtykyy@***. Handan City Eye Hospital Handan People's Republic of China. C-MER (Shenzhen) Dennis Lam Eye Hospital International Eye Research Institute of The Chinese University of Hong Kong (Shenzhen) Shenzhen People's Republic of China. The Eye Hospital WMU at Hangzhou Hangzhou People's Republic of China. Department of Ophthalmology The Second Hospital of Jilin University Changchun People's Republic of China. SenseTime Group Limited Hong Kong People's Republic of China. Department of Ophthalmology The Second Affiliated Hospital of Guizhou Medical University Kaili People's Republic of China. Department of Ophthalmology The Second Affiliated Hospital of Xi'an Jiaotong University Xi'an People's Republic of China. Department of Ophthalmology The Third Affiliated Hospital of Nanchang University Nanchang People's Republic of China. The First Hospital of Shijiazhuang City Shijiazhuang People's Republic of China. Hamilton Glaucoma Center Shiley Eye Institute Viterbi Family Department of Ophthalmology UC San Diego La Jolla CA United States. CISTIB Center for Computational Imaging and Simulation Technologies in Biomedicine Schools of Computing and Medicine University of Leeds Leeds UK. Singapore Eye Research Institute and Singapore National Eye Centre Singapore Singapore. ShenZhen Key Lab of Computer Vision and Pattern Recognition Shenzhen Institutes of Advanced Technology The Chinese Academy of Sci

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Global investments in pandemic preparedness and COVID-19: development assistance and domestic spending on health between 1990 and 2026

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The Lancet Global Health 2023年第3期11卷 e385-e413页

作者： Micah, Angela E. Bhangdia, Kayleigh Cogswell, Ian E. Lasher, Dylan Lidral-Porter, Brendan Maddison, Emilie R. Nguyen, Trang Nhu Ngoc Patel, Nishali Pedroza, Paola Solorio, Juan Stutzman, Hayley Tsakalos, Golsum Wang, Yifeng Warriner, Wesley Zhao, Yingxi Zlavog, Bianca S. Abbafati, Cristiana Abbas, Jaffar Abbasi-Kangevari, Mohsen Abbasi-Kangevari, Zeinab Abdelmasseh, Michael Abdulah, Deldar Morad Abedi, Aidin Abegaz, Kedir Hussein Abhilash, E.S. Aboagye, Richard Gyan Abolhassani, Hassan Abrigo, Michael R.M. Abubaker Ali, Hiwa Abu-Gharbieh, Eman Adem, Mohammed Hussien Afzal, Muhammad Sohail Ahmadi, Ali Ahmed, Haroon Ahmed Rashid, Tarik Aji, Budi Akbarialiabad, Hossein Akelew, Yibeltal Al Hamad, Hanadi Alam, Khurshid Alanezi, Fahad Mashhour Alanzi, Turki M. Al-Hanawi, Mohammed Khaled Alhassan, Robert Kaba Aljunid, Syed Mohamed Almustanyir, Sami Al-Raddadi, Rajaa M. Alvis-Guzman, Nelson Alvis-Zakzuk, Nelson J. Amare, Azmeraw T. Ameyaw, Edward Kwabena Amini-Rarani, Mostafa Amu, Hubert Ancuceanu, Robert Andrei, Tudorel Anwar, Sumadi Lukman Appiah, Francis Aqeel, Muhammad Arabloo, Jalal Arab-Zozani, Morteza Aravkin, Aleksandr Y. Aremu, Olatunde Aruleba, Raphael Taiwo Athari, Seyyed Shamsadin Avila-Burgos, Leticia Ayanore, Martin Amogre Azari, Samad Baig, Atif Amin Bantie, Abere Tilahun Barrow, Amadou Baskaran, Pritish Basu, Sanjay Batiha, Abdul-Monim Mohammad Baune, Bernhard T. Berezvai, Zombor Bhardwaj, Nikha Bhardwaj, Pankaj Bhaskar, Sonu Boachie, Micheal Kofi Bodolica, Virginia Botelho, João Silva Botelho Braithwaite, Dejana Breitborde, Nicholas J.K. Busse, Reinhard Cahuana-Hurtado, Lucero Catalá-López, Ferrán Chansa, Collins Charan, Jaykaran Chattu, Vijay Kumar Chen, Simiao Chukwu, Isaac Sunday Dadras, Omid Dandona, Lalit Dandona, Rakhi Dargahi, Abdollah Debela, Sisay Abebe Denova-Gutiérrez, Edgar Desye, Belay Dharmaratne, Samath Dhamminda Diao, Nancy Doan, Linh Phuong Dodangeh, Milad dos Santos, Wendel Mombaque Doshmangir, Leila Dube, John Eini, Ebrahim El Sayed Zaki, Maysaa El Tantawi, Maha Enyew, Daniel Berhanie Institute for Health Metrics and Evaluation University of Washington Seattle WA United States Department of Applied Mathematics University of Washington Seattle WA United States Department of Health Metrics Sciences School of Medicine University of Washington Seattle WA United States Nuffield Department of Medicine University of Oxford Oxford United Kingdom Department of Juridical and Economic Studies La Sapienza University Rome Italy Antai College of Economics Shanghai Jiao Tong University Shanghai China Non-communicable Diseases Research Center Tehran University of Medical Sciences Tehran Iran Research Center for Immunodeficiencies Tehran University of Medical Sciences Tehran Iran Multiple Sclerosis Research Center Tehran University of Medical Sciences Tehran Iran Children’s Medical Center Tehran University of Medical Sciences Tehran Iran Department of Epidemiology and Biostatistics Tehran University of Medical Sciences Tehran Iran Tehran Heart Center Tehran University of Medical Sciences Tehran Iran Faculty of Medicine Tehran University of Medical Sciences Tehran Iran National Institute for Health Research Tehran University of Medical Sciences Tehran Iran Department of Pharmacology Tehran University of Medical Sciences Tehran Iran Department of Cardiology Tehran University of Medical Sciences Tehran Iran Sina Trauma and Surgery Research Center Tehran University of Medical Sciences Tehran Iran Digestive Diseases Research Institute Tehran University of Medical Sciences Tehran Iran Department of Neurology Tehran University of Medical Sciences Tehran Iran Social Determinants of Health Research Center Shahid Beheshti University of Medical Sciences Tehran Iran Department of Epidemiology Shahid Beheshti University of Medical Sciences Tehran Iran Department of Health Economics and Statistics Shahid Beheshti University of Medical Sciences Tehran Iran Department of Neurosurgery Shahid Beheshti University of Medical Sciences Tehran Iran Ophthalmic R

Background: The COVID-19 pandemic highlighted gaps in health surveillance systems, disease prevention, and treatment globally. Among the many factors that might have led to these gaps is the issue of the financing of national health systems, especially in low-income and middle-income countries (LMICs), as well as a robust global system for pandemic preparedness. We aimed to provide a comparative assessment of global health spending at the onset of the pandemic;characterise the amount of development assistance for pandemic preparedness and response disbursed in the first 2 years of the COVID-19 pandemic;and examine expectations for future health spending and put into context the expected need for investment in pandemic preparedness. Methods: In this analysis of global health spending between 1990 and 2021, and prediction from 2021 to 2026, we estimated four sources of health spending: development assistance for health (DAH), government spending, out-of-pocket spending, and prepaid private spending across 204 countries and territories. We used the Organisation for Economic Co-operation and Development (OECD)'s Creditor Reporting System (CRS) and the WHO Global Health Expenditure Database (GHED) to estimate spending. We estimated development assistance for general health, COVID-19 response, and pandemic preparedness and response using a keyword search. Health spending estimates were combined with estimates of resources needed for pandemic prevention and preparedness to analyse future health spending patterns, relative to need. Findings: In 2019, at the onset of the COVID-19 pandemic, US$9·2 trillion (95% uncertainty interval [UI] 9·1–9·3) was spent on health worldwide. We found great disparities in the amount of resources devoted to health, with high-income countries spending $7·3 trillion (95% UI 7·2–7·4) in 2019;293·7 times the $24·8 billion (95% UI 24·3–25·3) spent by low-income countries in 2019. That same year, $43·1 billion in development assistance was provided

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