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Ce-doped defective titanium oxide coating with antibacterial,antioxidant and anti-inflammatory properties for potential application of peri-implantitis treatment

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Rare Metals 2025年第1期44卷 472-488页

作者： Yun-Hao Chen Shi-Wei Guan Min Xing Kelvin Wai-Kwok Yeung Xuan-Yong Liu Wen-Hao Qian Jing-Bo Yin Jia-Jun Qiu School of Materials Science and Engineering Shanghai UniversityShanghai 200444China State Key Laboratory of High Performance Ceramics and Superfine Microstructure Shanghai Institute of CeramicsChinese Academy of SciencesShanghai 200050China Shanghai Xuhui District Dental Center Shanghai 200032China Department of Orthopaedics and Traumatology Li Ka Shing Faculty of MedicineThe University of Hong KongHong Kong 999077China School of Chemistry and Materials Science Hangzhou Institute for Advanced StudyUniversity of Chinese Academy of SciencesHangzhou 310024China

Implant-related infections and tissue inflammation are the main factors for *** of antibacterial activity and poor soft tissue sealing property increase the occurrence probability of *** prevent and treat peri-implantitis,cerium-doped defective titanium oxide coatings are prepared on medical titanium surfaces by plasma electrolytic oxidation and thermal reduction *** the darkness,Ce-doped defective titanium oxide coatings with micro-porous structure surface can inhibit the bacteria adhesion to some extent with antibacterial rates of 38.0%against *** and 65.0%against *** near infrared(NIR)irradiation,Ce-doped defective titanium oxide coatings show good photothermal antibacterial activity with antibacterial rates of 99.9%against *** and 99.9%against ***,with the increasing content of Ce-doping,the coatings exhibit higher capacity to scavenge hydrogen peroxide(H2O2)and 2,2′-azinobis-(3-ethylbenzothiazoline-6-sulfonic acid)radical cation(ABTS^(·+)).The coatings with enhanced antioxidant effect can protect human gingival fibroblasts from oxidative stress damage by eliminating reactive oxygen species and promoting initial cell ***,Ce-doped coatings can regulate the immune microenvironment by up-regulating the expression of anti-inflammatory genes and down-regulating the pro-inflammatory *** vivo animal experiments further confirm the good antibacterial activity of Ce-doped defective titanium oxide coatings under NIR irradiation and good *** work provides a novel surface modification strategy for implant abutment,which shows good application prospects for preventing and treating peri-implantitis.

关键词： Peri-implantitis Antibacterial Soft tissue sealing Titanium oxide Cerium(Ce)

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Efficient factored gradient descent algorithm for quantum state tomography

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Physical Review Research 2024年第3期6卷 033034-033034页

作者： Yong Wang Lijun Liu Shuming Cheng Li Li Jie Chen College of Electronics and Information Engineering Department of Mathematics and Computer Science Shanghai Research Institute for Intelligent Autonomous Systems Institute for Advanced Study

Reconstructing the state of quantum many-body systems is of fundamental importance in quantum information tasks, but extremely challenging due to the curse of dimensionality. In this work, we present an efficient quantum tomography protocol that combines the state-factored with eigenvalue mapping to address the rank-deficient issue and incorporates a momentum-accelerated gradient descent algorithm to speed up the optimization process. We implement extensive numerical experiments to demonstrate that our factored gradient descent algorithm efficiently mitigates the rank-deficient problem and admits orders of magnitude better tomography accuracy and faster convergence. We also find that our method can accomplish the full-state tomography of random 11-qubit mixed states within one minute.

关键词： Quantum communication, protocols & technology Quantum engineering Quantum tomography

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Parallel Repetition of k-Player Projection Games 27

Parallel Repetition of k-Player Projection Games

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27th International Conference on Approximation Algorithms for Combinatorial Optimization Problems, APPROX 2024 and the 28th International Conference on Randomization and Computation, RANDOM 2024

作者： Bhangale, Amey Braverman, Mark Khot, Subhash Liu, Yang P. Minzer, Dor Department of Computer Science and Engineering University of California RiversideCA United States Department of Computer Science Princeton University NJ United States Department of Computer Science Courant Institute of Mathematical Sciences New York University NY United States School of Mathematics Institute for Advanced Study PrincetonNJ United States Department of Mathematics Massachusetts Institute of Technology CambridgeMA United States

We study parallel repetition of k-player games where the constraints satisfy the projection property. We prove exponential decay in the value of a parallel repetition of projection games with a value less than 1. ... 详细信息

ISBN: (纸本)9783959773485

关键词： Multiplayer games Parallel Repetition Projection games

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Frontiers in high entropy alloys and high entropy functional materials

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Rare Metals 2024年第10期43卷 4639-4776页

作者： Wen-Tao Zhang Xue-Qian Wang Feng-Qi Zhang Xiao-Ya Cui Bing-Bing Fan Jia-Ming Guo Zhi-Min Guo Rui Huang Wen Huang Xu-Bo Li Meng-Ru Li Yan Ma Zhi-Hua Shen Yong-Gang Sun De-Zhuang Wang Fei-Yang Wang Li-Qiang Wang Nan Wang Tian-Li Wang Wei Wang Xiao-Yang Wang Yi-Han Wang Fu-Jie Yu Yu-Zhen Yin Ling-Kun Zhang Yi Zhang Jian-Yang Zhang Qi Zhao Yu-Ping Zhao Xin-Dong Zhu Yasir Sohail Ya-Nan Chen Tao Feng Qi-Long Gao Hai-Yan He Yong-Jiang Huang Zeng-Bao Jiao Hua Ji Yao Jiang Qiang Li Xiao-Ming Li Wei-Bing Liao Huai-Jun Lin Hui Liu Qi Liu Qing-Feng Liu Wei-Di Liu Xiong-Jun Liu Yang Lu Yi-Ping Lu Wen Ma Xue-Fei Miao Jie Pan Qing Wang Hong-Hui Wu Yuan Wu Tao Yang Wei-Ming Yang Qian Yu Jin-Yu Zhang Zhi-Gang Chen Liang Mao Yang Ren Bao-Long Shen Xun-Li Wang Zhe Jia He Zhu Zhen-Duo Wu Si Lan School of Materials Science and Engineering Nanjing University of Science and TechnologyNanjing 210094China Jiangsu Key Laboratory for Advanced Metallic Materials School of Materials Science and EngineeringSoutheast UniversityNanjing 211189China Department of Physics City University of Hong KongHongKong 999077China School of Materials Science and Engineering Tianjin UniversityTianjin 300072China School of Physics and Microelectronics Zhengzhou UniversityZhengzhou 450001China Department of Mechanical Engineering Research Institute for Advanced ManufacturingThe Hong Kong Polytechnic UniversityHong Kong 100872China Center of Electron Microscopy and State Key Laboratory of Silicon Materials School of Materials Science and EngineeringZhejiang UniversityHangzhou 310027China Key Laboratory of Solidification Control and Digital Preparation Technology(Liaoning Province) School of Materials Science and EngineeringDalian University of TechnologyDalian 116024China Institute of Advanced Wear&Corrosion Resistance and Functional Materials Jinan UniversityGuangzhou 510632China School of Mechanics and Civil Engineering China University of Mining and TechnologyXuzhou 221116China School of Physical Sciences Great Bay UniversityDongguan 523000China School of Materials Science and Engineering Harbin Institute of TechnologyHarbin 150001China State Key Laboratory of Materials-Oriented Chemical Engineering College of Chemical EngineeringNanjing Tech UniversityNanjing 211816China Beijing Advanced Innovation Center for Materials Genome Engineering Research Institute for Carbon NeutralityUniversity of Science and Technology BeijingBeijing 100083China Department of Mechanical Engineering The University of Hong KongHong Kong 999077China School of Computing Macquarie UniversitySydney 2113Australia Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province College of Physics and Optoelectronic EngineeringShenzhen UniversityShenzhen 518060China State Key Laborato

Owing to their exceptional properties,high-entropy alloys(HEAs)and high-entropy materials have emerged as promising research areas and shown diverse ***,the recent advances in the field are comprehensively reviewed,organized into five *** first section introduces the background of HEAs,covering their definition,significance,application prospects,basic properties,design principles,and *** subsequent section focuses on cutting-edge high-entropy structural materials,highlighting developments such as nanostructured alloys,grain boundary engineering,eutectic systems,cryogenic alloys,thin films,micro-nano-lattice structures,additive manufacturing,high entropy metallic glasses,nano-precipitate strengthened alloys,composition modulation,alloy fibers,and refractory *** the following section,the emphasis shifts to functional materials,exploring HEAs as catalysts,magneto-caloric materials,corrosion-resistant alloys,radiation-resistant alloys,hydrogen storage systems,and materials for ***,the review encompasses functional high-entropy materials outside the realm of alloys,including thermoelectric,quantum dots,nanooxide catalysts,energy storage materials,negative thermal expansion ceramics,and high-entropy wave absorption *** paper concludes with an outlook,discussing future directions and potential growth areas in the *** this comprehensive review,researchers,engineers,and scientists may gain valuable insights into the recent progress and opportunities for further exploration in the exciting domains of high-entropy alloys and functional materials.

关键词： High entropy alloys Cutting-edge structural materials Cutting-edgefunctional materials

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Unsupervised Adaptive Lesion Segmentation with Similarity Based Cross Pseudo Supervision 7

Unsupervised Adaptive Lesion Segmentation with Similarity Ba...

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7th Asian Conference on Artificial Intelligence Technology, ACAIT 2023

作者： Zhu, Yuxin Li, Shuhao Yang, Aodi Feng, Mei Pu, Xiaorong Ren, Yazhou University of Electronic Science And Technology of China School of Computer Science And Engineering China The Third People's Hospital of Sichuan Department of Medical Oncology China University of Electronic Science And Technology of China School of Computer Science And Engineering Shenzhen Institute For Advanced Study China

ISBN: (纸本)9798350359145

Notable advancement has been made in lesion segmentation based on deep learning. Nonetheless, the effectiveness of deep learning heavily relies on the availability of a substantial amount of high-quality labeled data, which is labor-intensive and expensive to require. Moreover, when applied to a different domain, deep learning-based lesion segmentation methods often experience a decline in performance due to variations in device vendors and patient populations. The unsupervised domain adaptation method is proposed to tackle the domain discrepancy problem. There are certain similarities between semi-supervised learning and unsupervised domain adaptation. From an application perspective, semi-supervised learning models can be used to solve unsupervised domain adaptation *** this end, we introduce the cross-pseudo-supervision mechanism in the semi-supervised field for unsupervised adaptive lesion segmentation. However, the method ignores the similar characteristics in medical images. To fully leverage the semantic similarity between domains, a novel similarity-based cross-pseudo-supervised lesion segmentation model is proposed. The proposed model employs a U-Net encoder, trained on source domain, to extract features from both the source and target domains. Subsequently, cosine similarity is computed based on these extracted features. The obtained similarity scores are then employed to weigh the source samples during the training process. The effectiveness of the proposed method is demonstrated through cross-domain experiments conducted on two publicly available COVID-19 lesion segmentation datasets. © 2023 IEEE.

关键词： Population statistics

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Aerodynamic Super-Repellent Surfaces

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Research 2024年第2期2023卷 115-122页

作者： Fanfei Yu Jinlong Yang Ran Tao Yao Tan Jinpei Wang Dehui Wang Longquan Chen Zuankai Wang Xu Deng Institute of Fundamental and Frontier Sciences University of Electronic Science and Technology of ChinaChengdu 610054P.R.China Department of Mechanical Engineering City University of Hong KongKowloonHong Kong Special Administrative Region 999077P.R.China School of Physics.University of Electronic Science and Technology of China Chengdu 610054P.R.China Department of Mechanical Engineering Hong Kong Polytechnic UniversityKowloonHong Kong Special Administrative Region 999077P.R.China Shenzhen Institute for Advanced Study University of Electronic Science and Technology of ChinaShenzhen 518110P.R.China

Repelling liquid drops from engineering surfaces has attracted great attention in a variety of *** achieve efficient liquid shedding,delicate surface textures are often introduced to sustain air pockets at the liquid-solid ***,those surfaces are prone to suffer from mechanical failure,which may bring reliability issues and thus limits their ***,inspired by the aerodynamic Leidenfrost effect,we present that impacting drops are directionally repelled from smooth surfaces supplied with an exogenous air *** theoretical analysis reveals that the synchronized nonwetting and oblique bouncing behavior is attributed to the aerodynamic force arising from the air *** versatility and practicability of our approach allow for drop repellency without the aid of any surface wettability treatment and also avoid the consideration of mechanical stability issues,which thereby provides a promising candidate for the applications that necessitate liquid shedding,e.g.,resolve the problem of tiny raindrop adhesion on the automobile side window during driving.

关键词： thereby driving attributed

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Target-oriented Reference Construction for supervised cell type identification in scRNA-seq

Target-oriented Reference Construction for supervised cell t...

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2024 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2024

作者： Wei, Xin Ma, Wenjing Wu, Zhijin Wu, Hao Brown University Department of Biostatistics United States University of Michigan Department of Biostatistics Ann Arbor United States Shenzhen University of Advanced Technology Faculty of Computer Science and Control Engineering Shenzhen China Chinese Academy of Sciences Shenzhen Institute of Advanced Technology Shenzhen China

ISBN: (纸本)9798350386226

Cell type identification is a crucial step in single-cell RNA-seq (scRNA-seq) data analysis. The supervised cell type identification method is a preferred solution due to its accuracy and efficiency. The performance of such methods highly depends on the quality of the reference data. Although there are many supervised cell type identification tools, no method currently exists for constructing reference data. Here, we develop Target-Oriented Reference Construction (TORC), a widely applicable strategy for constructing references based on target datasets in scRNA-seq supervised cell type identification. TORC focuses on alleviating differences in cell type composition between the reference and target sets. Extensive benchmarks on simulated and real data analyses demonstrate consistent improvements in cell type identification with TORC. © 2024 IEEE.

关键词： Self-supervised learning

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Liquid-like polymer lubricating surfaces:Mechanism and applications

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Nano Research 2024年第2期17卷 476-491页

作者： Dagui Wang Jinglong Yang Junchang Guo Zhijuan Duan Deihui Wang Fan Xia Fei Deng Xu Deng Yangtze Delta Region Institute(Huzhou) University of Electronic Science and Technology of ChinaHuzhou 313001China Institute of Fundamental and Frontier Sciences University of Electronic Science and Technology of ChinaChengdu 610054China State Key Laboratory of Biogeology and Environmental Geology Engineering Research Center of Nano-Geomaterials of Ministry of EducationFaculty of Materials Science and ChemistryChina University of GeosciencesWuhan 430070China Department of Nephrology Sichuan Provincial People’s HospitalUniversity of Electronic Science and Technology of ChinaChengdu 610054China Department of Nephrology Sichuan Provincial People’s Hospital Jinniu HospitalChengdu Jinniu District People’s HospitalChengdu 610054China Shenzhen Institute for Advanced Study University of Electronic Science and Technology of ChinaShenzhen 518110China

Liquid-like polymer lubricating surfaces(LPLSs)are solid substrates with highly flexible polymer chains grafted via covalent *** unique modification enables ultralow contact-angle hysteresis,repellency of various liquids and bulk ice,and *** distinctive wettability and universality of LPLSs have potential applications in liquid motion,biological detection,and environmental *** this review,we summarize the mechanisms,preparation,and applications of *** discuss the wettability and lubrication mechanisms of liquid droplets on *** then categorize LPLS fabrication into“grafted onto”and“grafted from”groups,depending on the type of *** highlight representative applications with recent developments in anti-complex liquid,anti-icing,anti-biological adhesions,biosensing,and photocatalytic ***,we discuss future challenges and outlooks for LPLSs.

关键词： liquid-like polymer surface lubricating wettability

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Longitudinal study on Puberty Onset and Adolescent Obesity—Suzhou City,Jiangsu Province,China,2012–2022

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China CDC weekly 2024年第45期6卷 1183-1187,I0001页

作者： Huiling Lyu Ziyao Ding Bowen Chen Di Han Xi Wang Xiao Jiang Jiale Hu Hui Shen Jia Hu School of Public Health Nanjing Medical UniversityNanjing CityJiangsu ProvinceChina Department of School Health Suzhou Center for Disease Prevention and ControlSuzhou CityJiangsu ProvinceChina Department of Computer and Information Science University of PennsylvaniaPhiladelphiaPAUSA Suzhou Institute of Advanced Study in Public Health Gusu SchoolNanjing Medical UniversitySuzhou CityJiangsu ProvinceChina

What is already known about this topic?The early onset of puberty increases the risk of cardiovascular *** research has focused on the association between the onset of puberty,based on sudden increases in height,and obesity in late *** is added by this report?This report assessed the age at take-off and age at peak height velocity for children and adolescents in China from 2012 to *** results indicated that age at take-off and age at peak height velocity were negatively associated with the risk of late adolescence obesity in boys,independent of childhood body mass index;however,no similar association was found in *** are the implications for public health practice?Puberty timing influences *** monitoring and management of pubertal development are necessary,and attention should be paid to sex differences.

关键词： les Pub Jiangsu

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The ubiquitin codes in cellular stress responses

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Protein & Cell 2024年第3期15卷 157-190页

作者： Xiangpeng Sheng Zhixiong Xia Hanting Yang Ronggui Hu Key Laboratory of Systems Health Science of Zhejiang Province School of Life ScienceHangzhou Institute for Advanced StudyUniversity of Chinese Academy of SciencesHangzhou 310024China State Key Laboratory of Molecular Biology Shanghai Institute of Biochemistry and Cell BiologyCenter for Excellence in Molecular Cell ScienceChinese Academy of SciencesShanghai 200031China State Key Laboratory of Animal Disease Control Harbin Veterinary Research InstituteChinese Academy of Agricultural SciencesHarbin 150069China Department of Neurology State Key Laboratory of Medical NeurobiologyInstitute for Translational Brain ResearchMOE Frontiers Center for Brain ScienceZhongshan HospitalFudan UniversityShanghai 200032China

Ubiquitination/ubiquitylation,one of the most fundamental post-translational modifications,regulates almost every critical cellular process in *** evidence has shown that essential components of numerous biological processes undergo ubiquitination in mammalian cells upon exposure to diverse stresses,from exogenous factors to cellular reactions,causing a dazzling variety of functional *** forms of ubiquitin sig-nals generated by ubiquitylation events in specific milieus,known as ubiquitin codes,constitute an intrinsic part of myriad cellular stress *** ubiquitination events,leading to proteolytic turnover of the substrates or just switch in functionality,initiate,regulate,or supervise multiple cellular stress-associated responses,supporting adaptation,homeostasis recovery,and survival of the stressed *** this review,we attempted to summarize the crucial roles of ubiquitination in response to different environmental and intracellular stresses,while discussing how stresses modulate the ubiquitin *** review also updates the most recent advances in understanding ubiquitination machinery as well as different stress responses and discusses some important questions that may warrant future investigation.

关键词： ubiquitin E3 ligase environmental stresses intercellular stresses stress response homeostasis

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