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A Review of Deep Learning for Biomedical Signals: Current Applications, Advancements, Future Prospects, Interpretation, and Challenges

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computers, Materials and Continua 2025年第3期83卷 3753-3841页

作者： Ali Mohammad Alqudah Zahra Moussavi Biomedical Engineering Program University of Manitoba Winnipeg MB R3T 2N2 Canada Department of Electrical and Computer Engineering University of Manitoba Winnipeg MB R3T 2N2 Canada

This review presents a comprehensive technical analysis of deep learning (DL) methodologies in biomedical signal processing, focusing on architectural innovations, experimental validation, and evaluation frameworks. We systematically evaluate key deep learning architectures including convolutional neural networks (CNNs), recurrent neural networks (RNNs), transformer-based models, and hybrid systems across critical tasks such as arrhythmia classification, seizure detection, and anomaly segmentation. The study dissects preprocessing techniques (e.g., wavelet denoising, spectral normalization) and feature extraction strategies (time-frequency analysis, attention mechanisms), demonstrating their impact on model accuracy, noise robustness, and computational efficiency. Experimental results underscore the superiority of deep learning over traditional methods, particularly in automated feature extraction, real-time processing, cross-modal generalization, and achieving up to a 15% increase in classification accuracy and enhanced noise resilience across electrocardiogram (ECG), electroencephalogram (EEG), and electromyogram (EMG) signals. Performance is rigorously benchmarked using precision, recall, F1-scores, area under the receiver operating characteristic curve (AUC-ROC), and computational complexity metrics, providing a unified framework for comparing model efficacy. The survey addresses persistent challenges: synthetic data generation mitigates limited training samples, interpretability tools (e.g., Gradient-weighted Class Activation Mapping (Grad-CAM), Shapley values) resolve model opacity, and federated learning ensures privacy-compliant deployments. Distinguished from prior reviews, this work offers a structured taxonomy of deep learning architectures, integrates emerging paradigms like transformers and domain-specific attention mechanisms, and evaluates preprocessing pipelines for spectral-temporal trade-offs. It advances the field by bridging technical advancement

关键词： Deep learning deep models biomedical signals physiological signals biosignals

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Arabic text sentiment analysis and emotion classification using transformers

Arabic text sentiment analysis and emotion classification us...

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Electronics, Communications, and Computations (JAC-ECC), International Japan-Africa Conference on

作者： Nada Mossad Youssef Mohamed A Fares Ahmed B. Zaky Egypt-Japan University of Science and Technology (E-JUST) Alexandria Egypt The Department of Electrical Engineering The Computer Systems Engineering Program Faculty of Engineering at Shoubra Benha University

Sentiment analysis and emotion classification are two crucial components of natural language processing (NLP), which have been widely explored in recent years due to their broad applications. Sentiment analysis aims to identify the polarity of written texts, ranging from positive to negative. Meanwhile, emotion classification is focused on recognizing and categorizing the emotional states expressed in the text. To achieve a deeper understanding of sentiments and emotions, it's essential to utilize models like BERT transformers that can effectively interpret the context. The process begins with data preprocessing, including tokenization and noise removal, followed by fine-tuning techniques to adapt the BERT model to the proposed tasks. We employed the BERT model on four datasets obtained from various sources, including Twitter, news websites, and restaurant reviews, where each dataset represents a distinct Arabic dialect. Our proposed model outperforms commonly used techniques like LSTM and CNN, yielding superior results. Despite the progress made, there are still challenges to overcome, such as dealing with Arabic diacritics, the new Arabic Arabizi, which uses Latin characters, and handling Arabic idioms. Further research is required to address these challenges adequately.

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Meta-optic accelerators for object classification

Meta-optic accelerators for object classification

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2023 Flat Optics: Components to Systems, FLatOptics 2023 in Optica Imaging Congress - Part of Imaging and Applied Optics Congress 2023

作者： Zheng, Hanyu Liu, Quan Zhou, You Kravchenko, Ivan I. Huo, Yuankai Valentine, Jason Department of Electrical and Computer Engineering Vanderbilt University NashvilleTN37212 United States Department of Computer Science Vanderbilt University NashvilleTN37212 United States Department of Mechanical Engineering Vanderbilt University NashvilleTN37212 United States Interdisciplinary Materials Science Program Vanderbilt University NashvilleTN37212 United States Center for Nanophase Materials Sciences Oak Ridge National Laboratory Oak RidgeTN37830 United States

A meta-optic platform for accelerating object classification is demonstrated. End-to-end design is used to co-optimize the optical and digital systems resulting in high-speed classifiers that are demonstrated for hand... 详细信息

ISBN: (纸本)9781957171289

关键词： Imaging systems Machine vision Neural networks Optical components Optical neural systems Optical systems

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Delayed Muscle Activity in Stroke Survivors with Upper-Limb Hemiparesis

Delayed Muscle Activity in Stroke Survivors with Upper-Limb ...

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Annual International Conference of the IEEE engineering in Medicine and Biology Society (EMBC)

作者： Danielle R. Lopez Caleb J. Thomson Fredi R. Mino Steven R. Edgely Patrick P. Maitre Marta M. Iversen Jacob A. George Interdepartmental Neuroscience Program University of Utah Salt Lake City UT USA Department of Biomedical Engineering University of Utah Department of Electrical and Computer Engineering University of Utah Department of Physical Medicine and Rehabilitation University of Utah Departments of Electrical and Computer Engineering and Physical Medicine and Rehabilitation University of Utah

Stroke is the leading cause of disability worldwide, and nearly 80% of stroke survivors suffer from upper-limb hemiparesis. Myoelectric exoskeletons can restore dexterity and independence to stroke survivors with upper-limb hemiparesis. However, the ability of patients to dexterously control myoelectric exoskeletons is limited by an incomplete understanding of the electromyographic (EMG) hallmarks of hemiparesis, such as muscle weakness and spasticity. Here we show that stroke survivors with upper-limb hemiparesis suffer from delayed voluntary muscle contraction and delayed muscle relaxation. We quantified the time constants of EMG activity associated with initiating and terminating voluntary hand grasps and extensions for both the paretic and non-paretic hands of stroke survivors. We found that the initiation and termination time constants were greater on the paretic side for both hand grasps and hand extensions. Notably, the initiation time constant during hand extension was approximately three times longer for the paretic hand than for the contralateral non-paretic hand (0.618 vs 0.189 s). We also show a positive correlation between the initiation and termination time constants and clinical scores on the Modified Ashworth Scale. The difficulty stroke survivors have in efficiently modulating their EMG presents a challenge for appropriate control of assistive myoelectric devices, such as exoskeletons. This work constitutes an important step towards understanding EMG differences after stroke and how to accommodate these EMG differences in assistive myoelectric devices. Real-time quantitative biofeedback of EMG time constants may also have broad implications for guiding rehabilitation and monitoring patient *** Relevance— After a stroke, muscle activity changes, and these changes make it difficult to use muscle activity to drive assistive and rehabilitative technologies. We identified slower muscle contraction and muscle relaxation as a key difference i

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Deep Learning Networks for Handwritten Bangla Character Recognition

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IAENG International Journal of Applied Mathematics 2023年第4期53卷 1页

作者： Begum, H. Islam, M.M. Eva, H.S. Emon, N.H. Siddique, F.A. Department of Electrical and Electronic Engineering East West University A/2 Aftabnagar Dhaka Bangladesh Department of Electrical Engineering and Computer Science South Dakota State University United States Engineering and Design Department Reverie Power and Automation Engineering Limited Bangladesh Program in Smart System Integrated Solutions Aalto University Finland

In recent years, deep convolutional networks (DCNN) have gained popularity for different classification (or recognition) tasks. In this paper, three well known DCNN structures were used, i.e., AlexNet, SqueezeNet and GoogLeNet, and their classification performances in recognizing handwritten Bangla isolated characters were compared. These networks have simpler structures compared to the recent DCNNs. Experiments on a standard Bangla database revealed that the overall performance of GoogLeNet is slightly better than the other two networks. Further analysis using saliency maps of the test samples revealed the important features that are learned by the networks for classifying characters. This information led us to understand why classification of some samples fail and how to rectify these. © (2023), (International Association of Engineers). All Rights Reserved.

关键词： Classification (of information)

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Opto2P-FCM: A MEMS Based Miniature Two-Photon Microscope with Patterned Optogenetic Stimulation

Opto2P-FCM: A MEMS Based Miniature Two-Photon Microscope wit...

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Microscopy Histopathology and Analytics, Microscopy 2024 - Part of Optica Biophotonics Congress: Biomedical Optics

作者： Futia, Gregory L. Zohrabi, Mo McCullough, Connor Teel, Alec de Souza, Fabio Simoes Oroke, Ryan Bright, Victor M. Restrepo, Diego Gopinath, Juliet T. Gibson, Emily A. Department of Bioengineering University of Colorado Anschutz Medical Campus AuroraCO80045 United States Department of Cell and Developmental Biology University of Colorado Anschutz Medical Campus AuroraCO80045 United States Department of Electrical Computer and Energy Engineering University of Colorado BoulderCO80309 United States Department of Mechanical Engineering University of Colorado BoulderCO80309 United States Department of Physics University of Colorado BoulderCO80309 United States Materials Science and Engineering Program University of Colorado BoulderCO80309 United States

Miniaturized microscopes for monitoring neural activity are an indispensable tool for neuroscience research. We present a novel MEMS based miniature microscope with patterned optogenetic stimulation capabilities enabl... 详细信息

ISBN: (纸本)9781957171340

关键词： Microscopes

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UAV-Based Optimization for Fruit Counting in Greenhouses

UAV-Based Optimization for Fruit Counting in Greenhouses

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International Conference on Unmanned Aircraft Systems (ICUAS)

作者： João Vítor R. Vasconcelos Thayron M. Hudson André G. dos Santos Martin Saska Alexandre S. Brandão Department of Electrical Engineering Núcleo de Especialização em Robótica Graduate Program on Computer Science Federal Univer-sity of Vicosa Vicosa MG Brazil Graduate Program on Computer Science Federal University of Vicosa Vicosa MG Brazil Department of Cybernetics Multi-robot Systems Group Faculty of Electrical Engineering Czech Technical University in Prague Czech Republic

ISBN: (数字)9798350357882

ISBN: (纸本)9798350357899

This paper presents a solution for counting fruit in agricultural greenhouses using Unmanned Aerial Vehicles (UAV s). Initially, a heuristic based on Simulated Annealing was used to optimize the UAV's trajectory, ensuring efficient coverage of the beds. Next, digital image processing (DIP) techniques were implemented to count the fruit, including depth segmentation, application of bounding boxes, color filtering, and element counting. The DIP accuracy was evaluated in multiple scenarios and the results indicate high reliability in fruit counting, with the potential to optimize agricultural operations and provide valuable information to producers. Possible future improvements could include further refinements in image processing to increase the accuracy of counting other fruits. Ultimately, this work contributes to the advancement of automation in agriculture by offering a viable and efficient solution for counting fruit in greenhouses using UAV s.

关键词： Image segmentation Accuracy Image color analysis Greenhouses Simulated annealing Autonomous aerial vehicles Trajectory

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ReViT: A Hybrid Approach for BCLC Staging of Hepatocellular Carcinoma Using 3D CT with Multiple Instance Learning

ReViT: A Hybrid Approach for BCLC Staging of Hepatocellular ...

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2024 IEEE-EMBS International Conference on Biomedical and Health Informatics, BHI 2024

作者： Chang, Shun-Cheng Yu, Hsin-Pei Hsieh, Yi-Hsien Wang, Pochuang Wang, Weichung Su, Tung-Hung Kao, Jia-Horng Lin, Che Taipei10617 Taiwan Department of Computer Science and Information Engineering Ntu Taipei10617 Taiwan Institute of Applied Mathematical Sciences Ntu Taipei10617 Taiwan National Taiwan University Hospital Division of Gastroenterology and Hepatology Department of Internal Medicine Taipei10048 Taiwan Department of Electrical Engineering Ntu Taipei10617 Taiwan Center for Advanced Computing and Imaging in Biomedicine Ntu Taipei10617 Taiwan Smart Medicine and Health Informatics Program Ntu Taipei10617 Taiwan

ISBN: (纸本)9798350351552

Deep learning has revolutionized medical imaging, offering advanced methods for accurate diagnosis and treatment planning. The BCLC staging system is crucial for staging Hepatocellular Carcinoma (HCC), a high-mortality cancer. An automated BCLC staging system could significantly enhance diagnosis and treatment planning efficiency. However, we found that BCLC staging, which is directly related to the size and number of liver tumors, aligns well with the principles of the Multiple Instance Learning (MIL) framework. To effectively achieve this, we proposed a new preprocessing technique called Masked Cropping and Padding(MCP), which addresses the variability in liver volumes and ensures consistent input sizes. This technique preserves the structural integrity of the liver, facilitating more effective learning. Furthermore, we introduced Re ViT, a novel hybrid model that integrates the local feature extraction capabilities of Convolutional Neural Networks (CNNs) with the global context modeling of Vision Transformers (ViTs). Re ViT leverages the strengths of both architectures within the MIL framework, enabling a robust and accurate approach for BCLC staging. We will further explore the trade-off between performance and interpretability by employing TopK Pooling strategies, as our model focuses on the most informative instances within each bag. © 2024 IEEE.

关键词： Convolutional neural networks

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A BCLC Staging System for Hepatocellular Carcinoma using Swin Transformer and CT Imaging 46

A BCLC Staging System for Hepatocellular Carcinoma using Swi...

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46th Annual International Conference of the IEEE engineering in Medicine and Biology Society, EMBC 2024

作者： Chang, Shun-Cheng Wang, Pochuang Wang, Weichung Su, Tung-Hung Kao, Jia-Horng Lin, Che Taipei10617 Taiwan Department of Computer Science and Information Engineering Ntu Taipei10617 Taiwan Institute of Applied Mathematical Sciences Ntu Taipei10617 Taiwan Division of Gastroenterology and Hepatology Department of Internal Medicine National Taiwan University Hospital Taipei10048 Taiwan Department of Electrical Engineering Ntu Taipei10617 Taiwan Center for Advanced Computing and Imaging in Biomedicine Ntu Taipei10617 Taiwan Smart Medicine and Health Informatics Program Ntu Taipei10617 Taiwan

ISBN: (纸本)9798350371499

The Barcelona Clinic Liver Cancer (BCLC) staging system plays a crucial role in clinical planning, offering valuable insights for effectively managing hepatocellular carcinoma. Accurate prediction of BCLC stages can significantly ease the workload on radiologists. However, few datasets are explicitly designed for discerning BCLC stages. Despite the common practice of appending BCLC labels to clinical data within datasets, the inherent imbalance in BCLC distribution is further amplified by the diverse purposes for which datasets are curated. In this study, we aim to develop a BCLC staging system using the advanced Swin Transformer model. Additionally, we explore the integration of two datasets, each originally intended for separate objectives, highlighting the critical challenge of preserving class distribution in practical study designs. This exploration is pivotal for ensuring the applicability of our developed staging system in the designed clinical settings. Our resulting BCLC staging system demonstrates an accuracy of 55.81% (±7.8%), contributing to advancing medical image-based research for predicting BCLC stages. © 2024 IEEE.

关键词： Distribution transformers

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DEAL: Decoupled Classifier with Adaptive Linear Modulation for Group Robust Early Diagnosis of MCI to AD Conversion

arXiv

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arXiv 2024年

作者： Lee, Donggyu Park, Juhyeon Moon, Taesup The Department of Electrical and Computer Engineering Sungkyunkwan University Suwon16419 Korea Republic of The Interdisciplinary Program in Artificial Intelligence Seoul National University Seoul08826 Korea Republic of The Department of Electrical and Computer Engineering Automation and Systems Research Institute Institute of New Media and Communications Interdisciplinary Program in Artificial Intelligence Artificial Intelligent Institute Seoul National University Seoul08826 Korea Republic of

While deep learning-based Alzheimer's disease (AD) diagnosis has recently made significant advancements, particularly in predicting the conversion of mild cognitive impairment (MCI) to AD based on MRI images, there remains a critical gap in research regarding the group robustness of the diagnosis. Although numerous studies pointed out that deep learning-based classifiers may exhibit poor performance in certain groups by relying on unimportant attributes, this issue has been largely overlooked in the early diagnosis of MCI to AD conversion. In this paper, we present the first comprehensive investigation of the group robustness in the early diagnosis of MCI to AD conversion using MRI images, focusing on disparities in accuracy between groups, specifically sMCI and pMCI individuals divided by age. Our experiments reveal that standard classifiers consistently underperform for certain groups across different architectures, highlighting the need for more tailored approaches. To address this, we propose a novel method, dubbed DEAL (DEcoupled classifier with Adaptive Linear modulation), comprising two key components: (1) a linear modulation of features from the penultimate layer, incorporating easily obtainable age and cognitive indicative tabular features, and (2) a decoupled classifier that provides more tailored decision boundaries for each group, further improving performance. Through extensive experiments and evaluations across different architectures, we demonstrate the efficacy of DEAL in improving the group robustness of the MCI to AD conversion prediction. © 2024, CC BY-NC-SA.

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