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Importance of considering microscopic structures in modeling brain stimulation

Brain stimulation 2025年第4期18卷 1150-1152页

作者： Zhen Qi Gregory M Noetscher Alton Miles Konstantin Weise Thomas R Knösche Cameron R Cadman Alina R Potashinsky Kelu Liu William A Wartman Guillermo Nunez Ponasso Marom Bikson Hanbing Lu Zhi-De Deng Aapo Nummenmaa Sergey N Makaroff Electrical and Computer Engineering Department Worcester Polytechnic Institute Worcester MA USA. Electrical and Computer Engineering Department Worcester Polytechnic Institute Worcester MA USA. Electronic address: gregn@wpi.edu. Max Planck Institute for Human Cognitive and Brain Sciences Leipzig Germany Leipzig University of Applied Sciences (HTWK) Faculty of Engineering Leipzig Germany. Max Planck Institute for Human Cognitive and Brain Sciences Leipzig Germany. Department of Biomedical Engineering The City College of New York New York NY USA. Neuroimaging Research Branch NIDA Intramural Research Program National Institutes of Health Baltimore MD USA. Computational Neurostimulation Research Program Noninvasive Neuromodulation Unit Experimental Therapeutics and Pathophysiology Branch NIMH National Institutes of Health Baltimore MD USA. Massachusetts General Hospital Harvard Medical School Boston MA USA. Electrical and Computer Engineering Department Worcester Polytechnic Institute Worcester MA USA Massachusetts General Hospital Harvard Medical School Boston MA USA Department of Mathematical Sciences Worcester Polytechnic Institute Worcester MA USA.

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Sample Preconcentration Through Airjet-Induced Liquid Phase Enrichment

SSRN

引用

SSRN 2023年

作者： Wang, Edward Laurent, Louise C. Hall, Drew A. Lo, Yu-Hwa Department of Aerospace and Mechanical Engineering Materials Science and Engineering Program University of California La Jolla San DiegoCA United States Sanford Consortium of Regenerative Medicine United States Department of Electrical and Computer Engineering University of California La Jolla San DiegoCA United States Department of Bioengineering

Sample preparation is essential for nucleic acid assays, affecting their sensitivity and reliability. However, this process often results in a significant loss or dilution of the analyte, which becomes a bottleneck that limits downstream assay performance, particularly for assays that accept a limited input sample volume. To overcome this challenge, we present an evaporative-based sample enrichment method that uses an airjet to concentrate analytes within a small, defined volume by reversing the coffee-ring effect. A small, concentrated sample can then be collected for analysis to increase the initial sample load. The effectiveness of the reported airjet enrichment was quantified using qPCR of λ-DNA, HeLa-S3 RNA, and heat-inactivated SARS-CoV-2 samples. Comparisons between airjet enrichment and conventional evaporative concentration methods demonstrated significant advantages of airjet enrichment, including the ability to concentrate a high percentage of analyte within a 1 µL volume. The enrichment method was then integrated and adapted for various fluid volumes commonly found in nucleic acid sample preparation procedures. Here, airjet enrichment reduced the overall [[EQUATION]] by an average of 9.27 cycles for each analyte, resulting in a 600-fold enrichment from the initial concentration. In addition, to perform selective enrichment and prevent salt-based interference in downstream analysis, PEG was added to reduce the co-enrichment of salt. These studies show how airjet enrichment technology can be easily integrated into existing laboratory protocols with minimal modification and significantly improve the performance of nucleic acid amplification assays. © 2023, The Authors. All rights reserved.

关键词： Biomolecules

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Hierarchical B-Frame Video Coding Using Two-Layer CANF Without Motion Coding

Hierarchical B-Frame Video Coding Using Two-Layer CANF Witho...

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Conference on computer Vision and Pattern Recognition (CVPR)

作者： David Alexandre Hsueh-Ming Hang Wen-Hsiao Peng Electrical Engineering and Computer Science International Graduate Program National Yang Ming Chiao Tung University Hsinchu Taiwan Institute of Electronics National Yang Ming Chiao Tung University Hsinchu Taiwan Department of Computer Science National Yang Ming Chiao Tung University Hsinchu Taiwan

Typical video compression systems consist of two main modules: motion coding and residual coding. This general architecture is adopted by classical coding schemes (such as international standards H.265 and H.266) and deep learning-based coding schemes. We propose a novel B-frame coding architecture based on two-layer Conditional Augmented Normalization Flows (CANF). It has the striking feature of not transmitting any motion information. Our proposed idea of video compression without motion coding offers a new direction for learned video coding. Our base layer is a low-resolution image compressor that replaces the full-resolution motion compressor. The low-resolution coded image is merged with the warped high-resolution images to generate a high-quality image as a conditioning signal for the enhancement-layer image coding in full resolution. One advantage of this architecture is significantly reduced computational complexity due to eliminating the motion information compressor. In addition, we adopt a skip-mode coding technique to reduce the transmitted latent samples. The rate-distortion performance of our scheme is slightly lower than that of the state-of-the-art learned B-frame coding scheme, B-CANF, but outperforms other learned B-frame coding schemes. However, compared to B-CANF, our scheme saves 45% of multiply-accumulate operations (MACs) for encoding and 27% of MACs for decoding. The code is available at https://***.

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Dementia Detection by Shopping Refugees Support Robot 2

Dementia Detection by Shopping Refugees Support Robot

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2nd IEEE Global Conference on Life Sciences and Technologies, LifeTech 2020

作者： Kishimoto, Yuta Arai, Kenichi Imai, Tetsuo Kobayashi, Toru Nagasaki University Computer and Information Science Program Graduate School of Engineering Nagasaki Japan Nagasaki University Division of Electrical Engineering and Computer Science Graduate School of Engineering Nagasaki Japan

ISBN: (纸本)9781728170633

We have developed the Shopping Refugees Support Robot that enables the elderly to order items through Social Networking Service (SNS) by voice conversation without relying on smartphones. This paper proposes a detection method of dementia signs using this Robot. Concretely, deterioration of cognitive function is detected by the evaluation of short-term memory utilizing order history of the Robot. We expect detection of dementia signs on a daily basis without making the elderly person conscious of having a dementia test, by information that only the person knows. We implemented a prototype and confirmed its functional validity. © 2020 IEEE.

关键词： Internet of things

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TEAM: Task-Clustering and Enhanced Adaptability for Meta-Reinforcement Learning on Robotics Through Multi-Task Diffusion and Optimization

TEAM: Task-Clustering and Enhanced Adaptability for Meta-Rei...

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IEEE International Conference on Robotic Computing (IRC)

作者： Joshua Ho Chien-Min Wang Chung-Ta King Chi-Wei Feng Shih-Yun Sunkuan Social Networks and Human-Centered Computing Program Taiwan International Graduate Program Institute of Information Science Academia Sinica Taipei Taiwan Institute of Information Systems and Applications National Tsing Hua University Hsinchu Taiwan Department of Computer Science National Tsing Hua University Hsinchu Taiwan Department of Electrical Engineering National Taiwan University Taipei Taiwan

ISBN: (数字)9798331521554

ISBN: (纸本)9798331521561

The ability of robots to imitate human learning strategies-rapidly adapting to new tasks without large datasets-has garnered significant attention in meta-learning. Meta-reinforcement learning seeks to enhance robotic agent flexibility across diverse tasks and contexts, offering promise where single-task learning often fails. Despite advancements like multi-task diffusion models and task-weighted optimization mechanisms, effectively training tasks with varying complexities simultaneously remains a major challenge. This paper introduces a novel meta-reinforcement learning method that addresses this issue by clustering the training tasks of robotic arms based on semantic and trajectory similarities, while leveraging adaptive learning rates and task-specific weights proposed by the multitask optimization techniques. Our approach, TEAM, emphasizes performance-driven semantic clustering, optimizing based on robotic task similarity, complexity, and convergence objectives. We also integrate fast adaptive and multi-task optimization of the diffusion model to enhance computational efficiency and adaptability. More specifically, we introduce a cluster-specific optimization technique, using specialized parameters for each group to allow more refined task handling. The experimental validation demonstrates the effectiveness of this scalable method in improving performance, adaptability, and efficiency in real-world, heterogeneous robotic tasks, further advancing robotic computing in meta-reinforcement learning.

关键词： Training Metalearning program processors Semantics Multitasking Diffusion models Complexity theory Trajectory Robots Optimization

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Psychological Stress Classification Using Extreme Gradient Boosting Algorithm

Psychological Stress Classification Using Extreme Gradient B...

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International Conference on Information and Communication Technology Convergence (ICTC)

作者： Maria Mahardini Sakanti Viacheslav Siniaev Aurelia Amaris Win-Jet Luo Suhartono C. Bambang Dwi Kuncoro Graduate Institute of Precision Manufacturing National Chin-Yi University of Technology Taichung Taichung Taiwan Institute of Applied Computer Science ITMO University St. Petersburg Russian Federation Department of Informatics Engineering Faculty of Computer Science Universitas Brawijaya Malang Indonesia Ph.D. Program Prospective Technology of Electrical Engineering and Computer Science National Chin-Yi University of Technology Taichung Taichung Taiwan Department of Refrigeration Air Conditioning and Energy Engineering National Chin-Yi University of Technology Taichung Taiwan

ISBN: (数字)9798350364637

ISBN: (纸本)9798350364644

Stress, as a reaction to threatening situations, can raise heart rate and result in serious conditions that might cause significant damage or even be life-threatening. Traditional methods for evaluating stress, which rely on subjective self-reporting and clinical assessments, often suffer from biases and inconsistencies. Artificial intelligence models have been explored to predict stress levels more accurately. This paper investigates the application of Extreme Gradient Boosting in classifying psychological stress using the WESAD dataset, which includes parameters such as acceleration, electrocardiogram, electromyography, electrodermal activity, temperature, and respiration. The dataset was balanced and sampled to create a manageable subset for experimental. Extreme Gradient Boosting was chosen for its efficiency and scalability in handling complex datasets. The model was trained and validated, achieving a 95% accuracy in predicting stress levels. This study highlights the potential of integrating Extreme Gradient Boosting models into wearable devices for real-time stress monitoring. Future work involves optimizing the model to utilize fewer sensors without decreasing accuracy, ensuring it can be integrated into portable/wearable systems using tiny microcontrollers.

关键词： Accuracy Microcontrollers Psychology Human factors Predictive models Boosting Prediction algorithms Real-time systems Sensors Wearable devices

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Towards High Generalization Performance on Electrocardiogram Classification

Towards High Generalization Performance on Electrocardiogram...

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2021 Computing in Cardiology, CinC 2021

作者： Han, Hyeongrok Park, Seongjae Min, Seonwoo Choi, Hyun-Soo Kim, Eunji Kim, Hyunki Park, Sangha Kim, Jinkook Park, Junsang An, Junho Lee, Kwanglo Jeong, Wonsun Chon, Sangil Ha, Kwonwoo Han, Myungkyu Yoon, Sungroh Department of Electrical and Computer Engineering Seoul National University Seoul Korea Republic of HUINNO Co. Ltd Seoul Korea Republic of LG AI Research Seoul Korea Republic of Department of Computer Science and Engineering Kangwon National University Chuncheon Korea Republic of Department of Biological Sciences Interdisciplinary Program in Bioinformatics Interdisciplinary Program in Artificial Intelligence ASRI INMC Institute of Engineering Research Seoul National University Seoul Korea Republic of

ISBN: (纸本)9781665479165

Recently, many electrocardiogram (ECG) classification algorithms using deep learning have been proposed. The characteristics of ECG vary from dataset to dataset for various reasons (i.e., hospital, race, etc.). Therefore, it is important for a model to have high generalization performance consistently over all datasets. In this paper, as part of the PhysioNet / Computing in Cardiology Challenge 2021, we present a model developed to classify cardiac abnormalities from 12 lead and reduced-lead ECGs. In particular, to upgrade our previous model for improving generalization performance, we newly adopt constant-weighted cross-entropy loss, additional features, Mixup augmentation, and squeeze/excitation block, OneCycle learning rate scheduler, which are selected via evaluation of generalization performance using leave-one-dataset-out cross-validation setting. With the present model, our DSAILSNU team has received challenge scores of 0.55, 0.58, 0.58, 0.57 and 0.57 (ranked 2nd, 1st, 1st, 2nd, 2nd out of 39 teams) for the 12-lead, 6-lead, 4-lead, 3-lead, and 2-lead versions of the hidden test set, respectively. The present model achieves higher generalization performance over all versions of the hidden test set than the model submitted last year. © 2021 Creative Commons.

关键词： Deep learning

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Unbiased Estimation using Underdamped Langevin Dynamics

arXiv

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arXiv 2022年

作者： Ruzayqat, Hamza Chada, Neil K. Jasra, Ajay Applied Mathematics and Computational Science Program Computer Electrical and Mathematical Sciences and Engineering Division King Abdullah University of Science and Technology Thuwal23955-6900 Saudi Arabia

In this work we consider the unbiased estimation of expectations w.r.t. probability measures that have non-negative Lebesgue density, and which are known point-wise up-to a normalizing constant. We focus upon developing an unbiased method via the underdamped Langevin dynamics, which has proven to be popular of late due to applications in statistics and machine learning. Specifically in continuous-time, the dynamics can be constructed so that as the time goes to infinity they admit the probability of interest as a stationary measure. In many cases, time-discretized versions of the underdamped Langevin dynamics are used in practice which are run only with a fixed number of iterations. We develop a novel scheme based upon doubly randomized estimation as in [17, 19], which requires access only to time-discretized versions of the dynamics. The proposed scheme aims to remove the dicretization bias and the bias resulting from running the dynamics for a finite number of iterations. We prove, under standard assumptions, that our estimator is of finite variance and either has finite expected cost, or has finite cost with a high probability. To illustrate our theoretical findings we provide numerical experiments which verify our theory, which include challenging examples from Bayesian statistics and statistical *** Codes 60J22, 65C05, 65C40, 82C31, 62G08, 35Q56 © 2022, CC BY.

关键词： Dynamics

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AGV Detection in Industrial Environments through computer Vision

AGV Detection in Industrial Environments through Computer Vi...

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IEEE Latin American Robotics Symposium, LARS

作者： Wilson Eduardo Barioni Igor Pardal Latini André Lazzaretti Marco Teixeira Flavio Neves Lucia Valeria Ramos De Arruda Automation and Advanced Control System Laboratory (LASCA) Graduate Program in Electrical and Computer Engineering (CPGEI) Universidade Tecnologica Federal do Parana (UTFPR) Curitiba Parana Brazil

ISBN: (数字)9781665462808

ISBN: (纸本)9781665462815

Automated Guided Vehicles (AGVs) are usual in industrial settings, with an increasing economic impact on processes. They move through numerous environments inside factories, commonly navigating long distances, while performing several activities. The constant detection of such vehicles, especially in cases of maintenance and safety, is a main issue in an industry setting. Usually, this information could be provided by a supervisory system, but many applications are not so large as to make such a system viable. Thus, a solution via machine learning and computer vision is developed in this work, by using simple cameras, such as the factories' security cameras. As the industrial environment is a scenario with a lot of variation and noise, the Transfer Learning technique is used to improve the training step of the developed AGV detection system. Finally, a database with 1067 images is used to build and validate the model, achieving a result greater than 80% of F1-score for various confidence values.

关键词： Training computer vision Remotely guided vehicles Computational modeling Transfer learning Cameras Production facilities

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Reconfigurable Intelligent Surface-Aided Joint Radar and Covert Communications: Fundamentals, Optimization, and Challenges

arXiv

引用

arXiv 2022年

作者： Du, Hongyang Kang, Jiawen Niyato, Dusit Zhang, Jiayi Kim, Dong In The School of Computer Science and Engineering The Energy Research Institute @ NTU Interdisciplinary Graduate Program Nanyang Technological University Singapore The School of Computer Science and Engineering Nanyang Technological University Singapore The School of Electronic and Information Engineering Beijing Jiaotong University Beijing100044 China The Department of Electrical and Computer Engineering Sungkyunkwan University Suwon16419 Korea Republic of

Future wireless communication systems will evolve toward multi-functional integrated systems to improve spectrum utilization and reduce equipment sizes. A joint radar and communication (JRC) system, which can support simultaneous information transmission and target detection, has been regarded as a promising solution for emerging applications such as autonomous vehicles. In JRC, data security and privacy protection are critical issues. Thus, we first apply covert communication into JRC and propose a joint radar and covert communication (JRCC) system to achieve high spectrum utilization and secure data transmission simultaneously. In the JRCC system, an existence of sensitive data transmission is hidden from a maliciously observant warden. However, the performance of JRCC is restricted by severe signal propagation environment and hardware devices. Fortunately, reconfigurable intelligent surfaces (RISs) can change the signal propagation smartly to improve the networks performance with low cost. We first overview fundamental concepts of JRCC and RIS and then propose the RIS-aided JRCC system design. Furthermore, both covert communication and radar performance metrics are investigated and a game theory-based covert rate optimization scheme is designed to achieve secure communication. Finally, we present several promising applications and future directions of RIS-aided JRCC systems. © 2022, CC BY.

关键词： Data transfer

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