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Conference on computer Vision and Pattern Recognition (CVPR)

作者： Wei Shao YangYang Shi Daoqiang Zhang JunJie Zhou Peng Wan Ministry of Education College of Computer Science and Technology Nanjing University of Aeronautics and Astronautics Key Laboratory of Brain-Machine Intelligence Technology Nanjing China MIIT Key Laboratory of Pattern Analysis and Machine Intelligence Nanjing China

ISBN: (数字)9798350353006

ISBN: (纸本)9798350353013

The recent advance of deep learning technology brings the possibility of assisting the pathologist to predict the patients' survival from whole-slide pathological images (WSIs). However, most of the prevalent methods only worked on the sampled patches in specifically or randomly selected tumor areas of WSIs, which has very limited capability to capture the complex interactions between tumor and its surrounding micro-environment components. As a matter of fact, tumor is supported and nurtured in the heterogeneous tumor micro-environment(TME), and the detailed analysis of TME and their correlation with tumors are important to in-depth analyze the mechanism of cancer development. In this paper, we considered the spatial interactions among tumor and its two major TME components (i.e., lymphocytes and stromal fibrosis) and presented a Tumor Micro-environment Interactions Guided Graph Learning (TMEGL) algorithm for the prognosis prediction of human cancers. Specifically, we firstly selected different types of patches as nodes to build graph for each WSI. Then, a novel TME neighborhood organization guided graph embedding algorithm was proposed to learn node representations that can preserve their topological structure information. Finally, a Gated Graph Attention Network is applied to capture the survival-associated intersections among tumor and different TME components for clinical outcome prediction. We tested TMEGL on three cancer cohorts derived from The Cancer Genome Atlas (TCGA), and the experimental results indicated that TMEGL not only outperforms the existing WSI-based survival analysis models, but also has good explainable ability for survival prediction.

关键词： Pathology Analytical models Organizations Predictive models Semisupervised learning Prediction algorithms Pattern recognition

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Hydrogel wound dressings containing bioactive compounds originated from traditional Chinese herbs: A review

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Smart Materials in Medicine 2024年第1期5卷 153-165页

作者： Yang, Dan Chen, Hailan Wei, Hua Liu, An Wei, Dai-Xu Chen, Jing Institute of Medical Sciences The Second Hospital and Shandong University Center for Orthopaedics Cheeloo College of Medicine Shandong University Jinan250033 China Faculty of Animal Science and Technology Guangxi University Guangxi Nanning530004 China Key Laboratory of Colloid and Interface Chemistry Ministry of Education School of Chemistry and Chemical Engineering Shandong University Jinan250100 China Department of Orthopedics The Second Affiliated Hospital Zhejiang University School of Medicine Hangzhou310002 China Zigong Affiliated Hospital of Southwest Medical University Zigong Psychiatric Research Center Zigong Institute of Brain Science Zigong Sichuan Province 643002 China Key Laboratory of Resource Biology and Biotechnology in Western China Ministry of Education School of Medicine Faculty of Life Science & Medicine Northwest University Xi'an710069 China

Various factors can cause skin defects, resulting in the loss of physiological functions and even death due to severe concurrent infection. Dressings are often clinically used to fully cover the wounds to improve healing. Hydrogel wound dressings can be loaded with therapeutic compounds (e.g., curcumin) within their three-dimensional networks to enable the in situ delivery of compounds at skin defects for wound healing. In recent decades, natural herbal active components have gradually gained worldwide recognition owing to their safe and diverse therapeutic effects, and an increasing number of bioactive components can be loaded into hydrogels or directly act as hydrogel matrices to enhance safety and achieve the desired therapeutic effects. In this review, twelve bioactive compounds from natural Chinese herbs that can promote wound healing and their mechanism of action are summarized, and the latest research progress in the use of Chinese herbal hydrogels for wound treatment is reviewed. © 2023 The Authors

关键词： Hydrogels

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Game Generation via Large Language Models

Game Generation via Large Language Models

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IEEE Symposium on Computational Intelligence and Games, CIG

作者： Chengpeng Hu Yunlong Zhao Jialin Liu Department of Computer Science and Engineering Guangdong Key Laboratory of Brain-inspired Intelligent Computation Southern University of Science and Technology Shenzhen China LightSpeed Studios Tencent Shenzhen China

ISBN: (数字)9798350350678

ISBN: (纸本)9798350350685

Recently, the emergence of large language models (LLMs) has unlocked new opportunities for procedural content generation. However, recent attempts mainly focus on level generation for specific games with defined game rules such as Super Mario Bros. and Zelda. This paper investigates the game generation via LLMs. Based on video game description language, this paper proposes an LLM-based framework to generate game rules and levels simultaneously. Experiments demonstrate how the framework works with prompts considering different combinations of context. Our findings extend the current applications of LLMs and offer new insights for generating new games in the area of procedural content generation.

关键词： Video games Solid modeling Procedural generation Three-dimensional displays Large language models Prototypes Games

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Development of yellow-light TiO2 integrated photonics

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Optics Letters 2025年第11期50卷 3489-3492页

作者： Chen, Zequn Tang, Yiheng Wei, Maoliang Li, Xiaojing Sun, Boshu Wu, Yingchun Zou, Sishuo Huang, Ji Si, Ke Gong, Wei Lin, Hongtao Li, Lan Institute of Advanced Technology Westlake Institute for Advanced Study Hangzhou310024 China Zhejiang Key Laboratory of 3D Micro Nano Fabrication and Characterization School of Engineering Westlake University Hangzhou310030 China The State Key Lab of Brain-Machine Intelligence College of Information Science and Electronic Engineering Zhejiang University Hangzhou310027 China MOE Frontier Science Center for Brain Science & Brain-Machine Integration Zhejiang University Hangzhou310027 China Nanhu Brain-Computer Interface Institute Hangzhou311100 China College of Optical Science and Engineering Zhejiang University Hangzhou310027 China Westlake Institute for Optoelectronics Fuyang Zhejiang Hangzhou311421 China

Visible-light photonic integrated circuits (PICs) are rapidly emerging as a crucial technology to overcome the scaling challenges in quantum information processing and biosensing. Titanium dioxide (TiO2), with its high transparency in the visible range, is regarded as a promising material for facilitating the development of high-performance visible-light integrated systems. In this paper, we introduce a series of passive TiO2 integrated devices, which include waveguides, multimode interferometers (MMIs), and thermo-optic switches (TOSs), monolithically integrated for the first time to our knowledge at a working wavelength of 589 nm. A propagation loss of 5.46 ± 0.17 dB/cm demonstrates a significant improvement over previous reports on yellow-light TiO2 waveguides. This study marks the first fabrication of a TOS operating at 589 nm, featuring a TiO2 core and polymer cladding. Notably, it achieves a power consumption (Pπ) of 8.24 mW, which represents a threefold reduction compared to silicon nitride-based TOSs operating in the visible spectrum. These results offer new insight into the design and fabrication of visible waveguide-integrated devices, paving the way for future emerging applications, such as quantum information, sensors, and biomedical science. © 2025 Optica Publishing Group. All rights, including for text and data mining (TDM), Artificial Intelligence (AI) training, and similar technologies, are reserved.

关键词： Titanium dioxide

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Enabling Surrogate-Assisted Evolutionary Reinforcement Learning via Policy Embedding 1

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17th International Conference on Bio-Inspired Computing: Theories and Applications, BIC-TA 2022

作者： Tang, Lan Li, Xiaxi Zhang, Jinyuan Li, Guiying Yang, Peng Tang, Ke Guangdong Provincial Key Laboratory of Brain-Inspired Intelligent Computation Department of Computer Science and Engineering Southern University of Science and Technology Shenzhen518055 China Faculty of Engineering Shenzhen MSU-BIT University Shenzhen518172 China Research Institute of Trustworthy Autonomous Systems Southern University of Science and Technology Shenzhen518055 China Department of Statistics and Data Science Southern University of Science and Technology Shenzhen518055 China

ISBN: (数字)9789819915491

ISBN: (纸本)9789819915484

Evolutionary Reinforcement Learning (ERL) that applying Evolutionary Algorithms (EAs) to optimize the weight parameters of Deep Neural Network (DNN) based policies has been widely regarded as an alternative to traditional reinforcement learning methods. However, the evaluation of the iteratively generated population usually requires a large amount of computational time and can be prohibitively expensive, which may potentially restrict the applicability of ERL. Surrogate is often used to reduce the computational burden of evaluation in EAs. Unfortunately, in ERL, each individual of policy usually represents millions of weights parameters of DNN. This high-dimensional representation of policy has introduced a great challenge to the application of surrogates into ERL to speed up training. This paper proposes a PE-SAERL Framework to at the first time enable surrogate-assisted evolutionary reinforcement learning via policy embedding (PE). Empirical results on 5 Atari games show that the proposed method can perform more efficiently than the four state-of-the-art algorithms. The training process is accelerated up to 7x on tested games, comparing to its counterpart without the surrogate and PE. © 2023, The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd.

关键词： Reinforcement learning

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EAS-SNN: End-to-End Adaptive Sampling and Representation for Event-based Detection with Recurrent Spiking Neural Networks

arXiv

引用

arXiv 2024年

作者： Wang, Ziming Wang, Ziling Li, Huaning Qin, Lang Jiang, Runhao Ma, De Tang, Huajin College of Computer Science and Technology Zhejiang University Hangzhou310027 China State Key Laboratory of Brain-Machine Intelligence Zhejiang University Hangzhou310027 China

Event cameras, with their high dynamic range and temporal resolution, are ideally suited for object detection in scenarios with motion blur and challenging lighting conditions. However, while most existing approaches prioritize optimizing spatiotemporal representations with advanced detection backbones and early aggregation functions, the crucial issue of adaptive event sampling remains largely unaddressed. Spiking Neural Networks (SNNs), operating on an event-driven paradigm, align closely with the behavior of an ideal temporal event sampler. Motivated by this, we propose a novel adaptive sampling module that leverages recurrent convolutional SNNs enhanced with temporal memory, facilitating a fully end-to-end learnable framework for event-based detection. Additionally, we introduce Residual Potential Dropout (RPD) and Spike-Aware Training (SAT) to regulate potential distribution and address performance degradation encountered in spike-based sampling modules. Empirical evaluation on neuromorphic detection datasets demonstrates that our approach outperforms existing state-of-the-art spike-based methods with significantly fewer parameters and time steps. For instance, our method yields a 4.4% mAP improvement on the Gen1 dataset, while requiring 38% fewer parameters and only three time steps. Moreover, the applicability and effectiveness of our adaptive sampling methodology extend beyond SNNs, as demonstrated through further validation on conventional non-spiking models. Code is available at Github. Copyright © 2024, The Authors. All rights reserved.

关键词： Object detection

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OCET: One-Dimensional Convolution Embedding Transformer for Stock Trend Prediction 1

引用

17th International Conference on Bio-Inspired Computing: Theories and Applications, BIC-TA 2022

作者： Yang, Peng Fu, Lang Zhang, Jian Li, Guiying Department of Statistics and Data Science Southern University of Science and Technology Shenzhen518055 China Guangdong Provincial Key Laboratory of Brain-Inspired Intelligent Computation Department of Computer Science and Engineering Southern University of Science and Technology Shenzhen518055 China Research Institute of Trustworthy Autonomous Systems Southern University of Science and Technology Shenzhen518055 China Shenzhen Securities Information Co. Ltd. Shenzhen China

ISBN: (数字)9789819915491

ISBN: (纸本)9789819915484

Due to the strong data fitting ability of deep learning, the use of deep learning for quantitative trading has gradually sprung up in recent years. As a classical problem of quantitative trading, Stock Trend Prediction (STP) mainly predicts the movement of stock price in the future through the historical price information to better guide quantitative trading. In recent years, some deep learning work has made great progress in STP by effectively grasping long-term timing information. However, as a kind of real-time series data, short-term timing information is also very important, because stock trading is high-frequency and price fluctuates violently. And with the popularity of Transformer, there is a lack of an effective combination of feature extraction and Transformer in STP tasks. To make better use of short term information, we propose One-dimensional Convolution Embedding (OCE). Simultaneously, we introduce effective feature extraction with Transformer into STP problem to extract feature information and capture long-term timing information. By combining OCE and Transformer organically, we propose a noval STP prediction model, One-dimensional Convolution Embedding Transformer (OCET), to capture long-term and short-term time series information. Finally, OCET achieves a highest accuracy up to 0.927 in public benchmark FI-2010 When reasoning speed is twice that of SOTA models and a highest accuracy of 0.426 in HKGSAS-2020. Empirical results on these two datasets show that our OCET is significantly superior than other algorithms in STP tasks. Code are available at https://***/langgege-cqu/OCET. © 2023, The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd.

关键词： Convolution

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LICO: Explainable Models with Language-Image COnsistency

arXiv

引用

arXiv 2023年

作者： Lei, Yiming Li, Zilong Li, Yangyang Zhang, Junping Shan, Hongming Shanghai Key Laboratory of Intelligent Information Processing School of Computer Science Fudan University China Academy of Mathematics and Systems Science Chinese Academy of Sciences China Institute of Science and Technology for Brain-Inspired Intelligence and MOE Frontiers Center for Brain Science Fudan University China Shanghai Center for Brain Science and Brain-inspired Technology China

Interpreting the decisions of deep learning models has been actively studied since the explosion of deep neural networks. One of the most convincing interpretation approaches is salience-based visual interpretation, such as Grad-CAM, where the generation of attention maps depends merely on categorical labels. Although existing interpretation methods can provide explainable decision clues, they often yield partial correspondence between image and saliency maps due to the limited discriminative information from one-hot labels. This paper develops a Language-Image COnsistency model for explainable image classification, termed LICO, by correlating learnable linguistic prompts with corresponding visual features in a coarse-to-fine manner. Specifically, we first establish a coarse global manifold structure alignment by minimizing the distance between the distributions of image and language features. We then achieve fine-grained saliency maps by applying optimal transport (OT) theory to assign local feature maps with class-specific prompts. Extensive experimental results on eight benchmark datasets demonstrate that the proposed LICO achieves a significant improvement in generating more explainable attention maps in conjunction with existing interpretation methods such as Grad-CAM. Remarkably, LICO improves the classification performance of existing models without introducing any computational overhead during inference. Source code is made available at https://***/ymLeiFDU/LICO. Copyright © 2023, The Authors. All rights reserved.

关键词： Classification (of information)

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A Multi-objective Perspective Towards Improving Meta-Generalization

A Multi-objective Perspective Towards Improving Meta-General...

引用

International Joint Conference on Neural Networks (IJCNN)

作者： Weiduo Liao Ying Wei Qirui Sun Qingfu Zhang Hisao Ishibuchi Department of Computer Science City University of Hong Kong Department of Computer Science and Engineering Guangdong Provincial Key Laboratory of Brain-Inspired Intelligent Computation Southern University of Science and Technology School of Computer Science and Engineering Nanyang Technological University

ISBN: (数字)9798350359312

ISBN: (纸本)9798350359329

To improve meta-generalization, i.e., accommodating out-of-domain meta-testing tasks beyond meta-training ones, is of significance to extending the success of meta-learning beyond standard benchmarks. Previous heterogeneous meta-learning algorithms have shown that tailoring the global meta-knowledge by the learned clusters during meta-training promotes better meta-generalization to novel meta-testing tasks. Inspired by this, we propose a novel multi-objective perspective to sharpen the compositionality of the meta-trained clusters, through which we have empirically validated that the meta-generalization further improves. Grounded on the hierarchically structured meta-learning framework, we formulate a hypervolume loss to evaluate the degree of conflict between multiple cluster-conditioned parameters in the two-dimensional loss space over two randomly chosen tasks belonging to two clusters and two mixed tasks imitating out-of-domain tasks. Experimental results on more than 16 few-shot image classification datasets show not only improved performance on out-of-domain meta-testing datasets but also better clusters in visualization.

关键词： Metalearning Visualization Neural networks Clustering algorithms Benchmark testing Standards Image classification

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Effects of External Archives on the Performance of Multi-Objective Evolutionary Algorithms on Real-World Problems

Effects of External Archives on the Performance of Multi-Obj...

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Congress on Evolutionary Computation

作者： Yang Nan Tianye Shu Hisao Ishibuchi Department of Computer Science and Engineering Guangdong Provincial Key Laboratory of Brain-inspired Intelligent Computation Southern University of Science and Technology Shenzhen China

External archives have attracted more and more attention in the evolutionary multi-objective optimization (EMO) community. This is because a solution set selected from an external archive is usually better than the final population of an EMO algorithm. Whereas the effects of subset selection from external archives have already been investigated on artificial test problems, its effects on real-world problems have not been examined. In this paper, we examine the effects of subset selection from external archives for ten EMO algorithms on two real-world problem suites. Experimental results show that the performance improvement by subset selection is large for most algorithms and many problems but small for a few algorithms and a few problems (i.e., algorithm dependent and problem dependent).

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