MicroRNAs(miRNAs)are closely related to numerous complex human diseases,therefore,exploring miRNA-disease associations(MDAs)can help people gain a better understanding of complex disease *** increasing number of compu...
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MicroRNAs(miRNAs)are closely related to numerous complex human diseases,therefore,exploring miRNA-disease associations(MDAs)can help people gain a better understanding of complex disease *** increasing number of computational methods have been developed to predict ***,the sparsity of the MDAs may hinder the performance of many *** addition,many methods fail to capture the nonlinear relationships of miRNA-disease network and inadequately leverage the features of network and neighbor *** this study,we propose a deep matrix factorization model with variational autoencoder(DMFVAE)to predict potential *** first decomposes the original association matrix and the enhanced association matrix,in which the enhanced association matrix is enhanced by self-adjusting the nearest neighbor method,to obtain sparse vectors and dense vectors,***,the variational encoder is employed to obtain the nonlinear latent vectors of miRNA and disease for the sparse vectors,and meanwhile,node2vec is used to obtain the network structure embedding vectors of miRNA and disease for the dense ***,sample features are acquired by combining the latent vectors and network structure embedding vectors,and the final prediction is implemented by convolutional neural network with channel *** evaluate the performance of DMFVAE,we conduct five-fold cross validation on the HMDD v2.0 and HMDD v3.2 datasets and the results show that DMFVAE performs ***,case studies on lung neoplasms,colon neoplasms,and esophageal neoplasms confirm the ability of DMFVAE in identifying potential miRNAs for human diseases.
Fourier ptychographic microscopy (FPM) combines the concepts of phase retrieval algorithms and synthetic apertures and can solve the problem in which it is difficult to combine a large field of view with high resoluti...
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Fourier ptychographic microscopy (FPM) combines the concepts of phase retrieval algorithms and synthetic apertures and can solve the problem in which it is difficult to combine a large field of view with high resolution. However, the use of the coherent transfer function in conventional calculations to describe the linear transfer proc-ess of an imaging system can lead to ringing artifacts. In addition, the Gerchberg-Saxton iterative algorithm can cause the phase retrieval part of the FPM algorithm to fall into a local optimum. In this paper, Gaussian apodization coherent transfer function is proposed to describe the imaging process and is combined with an iterative method based on amplitude weighting and phase gradient descent to reduce the presence of ringing artifacts while ensuring the accuracy of the reconstructed results. In simulated experiments, the proposed algorithm is shown to give a smaller mean square error and higher structural similarity, both in the presence and absence of noise. Finally, the proposed algorithm is validated in terms of giving reconstruction results with high accuracy and high resolution, using images acquired with a new microscope system and open-source images. (c) 2023 Optica Publishing Group
This article presents a Symplectic Geometric Mode Decomposition (SGMD) method incorporating K-means clustering, coupled with wavelet denoising, for mitigating noise in Linear Frequency Modulation (LFM) signals. This m...
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The paper proposes a noise reduction algorithm based on symplectic Geometric Mode Decomposition (SGMD) and Savitzky-Golay (SG)filtering to address the issue of noise interference during signal transmission. Firstly, t...
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In this paper, a novel and comprehensive signal denoising method is proposed by combining Symplectic Geometric Modal Decomposition (SGMD) and Block Thresholding denoising. The proposed approach involves a three-step p...
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Aiming at the traditional blind source separation for the received single-channel mixed radar signal makes it difficult to accurately recover the source signal, a single-channel radar signal comprehensive separation m...
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A miniaturized reconfigurable bandpass chip filter with semi-lumped topology and Gallium Arsenide pseudomorphic High electron mobility transistor（GaAs pHEMT） technology is proposed. Semi-lumped topology is employed ...
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A miniaturized reconfigurable bandpass chip filter with semi-lumped topology and Gallium Arsenide pseudomorphic High electron mobility transistor（GaAs pHEMT） technology is proposed. Semi-lumped topology is employed to instead the traditional lumped inductor with microstrip transmission line, which can reduced the size of the tunable filter significantly. Three-order series and shunt resonated bandpass filter is implemented with shorted stubs and metal-insulator-metal capacitors. Two transmission zeros are introduced with the series resonator and the shunted GaAs FET. By tuning the gate bias circuit of the FET, the capacitance of the series resonator is changed and the bandwidth of the filter is adjusted correspondingly. An equivalent circuit model is developed to interpret the mechanism of the proposed filter circuit. A reconfigurable on chip filter sample operated at 10 GHz is fabricated to validate the design. Two fractional bandwidth of 14.3% and 23.5% are tuned with bias voltage of the FET, while insertion loss of 2.4 d B and 2.2 d B are observed with the filter, respectively. The area of the chip filter is 0.86 × 0.96 mm2and is equivalent to an electrical length of 0.08 × 0.09λg2at center frequency. Measurement results agree well with the simulation ones.
A wideband GCPW-SIW fed slots antenna in millimeter wave band is designed in this paper. The structure is composed of four inclined slots which are placed on the one side of the SIW with three shorting vias and fed by...
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A 38×38×4mm3 wideband circularly polarized (CP) antenna with Hybrid Metasurface (MTS) for wearable devices is proposed. The proposed antenna achieves CP radiation by cutting corners on a square microstrip pa...
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Reversible data hiding in encrypted domain (RDH-ED) fortifies data security and privacy safeguards while upholding the original data’s integrity and accessibility. Current research on RDH-ED focuses on 2D images, whi...
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