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48th IEEE International Conference on Acoustics, Speech and Signal Processing, ICASSP 2023

作者： Liu, Xiaokang Wang, Zhiqiang Hu, Kai Gao, Xieping Xiangtan University Key Laboratory of Intelligent Computing and Information Processing of Ministry of Education Xiangtan411105 China Xiangnan University College of Medical Imaging Laboratory and Rehabilitation Chenzhou423000 China Hunan Normal University Hunan Provincial Key Laboratory of Intelligent Computing and Language Information Processing Changsha410081 China

ISBN: (纸本)9781728163277

Unsupervised domain adaptation (UDA) attracts extra attention in medical image processing because no additional labels are required when adapting to different distributions. In this work, we propose a novel unsupervised domain adaptation framework named as Domain Expansion and PseudoLabeling (DEPL). We extend the domain of a labeled source domain data to four different distributed domains and use adversarial learning to align the image appearance level and feature level from the four different domains to the unlabeled target domain. In addition, we propose a selective pseudolabeling mechanism, namely using strong confidence pseudolabeling to boost model performance. We evaluate our model for the MR to CT adaptation segmentation task on the public dataset MMWHS. Compared to seven other state-of-the-art segmentation methods, our DEPL achieves the best Dice similarity coefficient by 82.4%, which is at least 3.9% higher than the other UDA segmentation methods. © 2023 IEEE.

关键词： Adversarial learning domain extension image segmentation Selective pseudo-labeling Unsupervised domain adaptive

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A multi-instance tumor subtype classification method for small PET datasets using RA-DL attention module guided deep feature extraction with radiomics features

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Computers in Biology and Medicine 2024年 174卷 108461-108461页

作者： Diao, Zhaoshuo Jiang, Huiyan Software College Northeastern University Shenyang110819 China Key Laboratory of Intelligent Computing in Medical Image Ministry of Education Northeastern University Shenyang110819 China

Background: Positron emission tomography (PET) is extensively employed for diagnosing and staging various tumors, including liver cancer, lung cancer, and lymphoma. Accurate subtype classification of tumors plays a crucial role in formulating effective treatment plans for patients. Notably, lymphoma comprises subtypes like diffuse large B-cell lymphoma and Hodgkin's lymphoma, while lung cancer encompasses adenocarcinoma, small cell carcinoma, and squamous cell carcinoma. Similarly, liver cancer consists of subtypes such as cholangiocarcinoma and hepatocellular carcinoma. Consequently, the subtype classification of tumors based on PET images holds immense clinical significance. However, in clinical practice, the number of cases available for each subtype is often limited and imbalanced. Therefore, the primary challenge lies in achieving precise subtype classification using a small dataset. Method: This paper presents a novel approach for tumor subtype classification in small datasets using RA-DL (Radiomics-DeepLearning) attention. To address the limited sample size, Support Vector Machines (SVM) is employed as the classifier for tumor subtypes instead of deep learning methods. Emphasizing the importance of texture information in tumor subtype recognition, radiomics features are extracted from the tumor regions during the feature extraction stage. These features are compressed using an autoencoder to reduce redundancy. In addition to radiomics features, deep features are also extracted from the tumors to leverage the feature extraction capabilities of deep learning. In contrast to existing methods, our proposed approach utilizes the RA-DL-Attention mechanism to guide the deep network in extracting complementary deep features that enhance the expressive capacity of the final features while minimizing redundancy. To address the challenges of limited and imbalanced data, our method avoids using classification labels during deep feature extraction and instead incorporates

关键词： Classification (of information)

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Dynamic Prediction of Intraoperative Hypotension Based on Hemodynamic Monitoring Data With a Transformer-Based Deep Learning Model

Dynamic Prediction of Intraoperative Hypotension Based on He...

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IEEE International Conference on Bioinformatics and Biomedicine (BIBM)

作者： Kai Yang Mucheng Ren Jun Xu Xian Zeng Jiangsu Key Laboratory of Intelligent Medical Image Computing School of Future Technology Nanjing University of Information Science and Technology Nanjing China

ISBN: (数字)9798350386226

ISBN: (纸本)9798350386233

Timely prediction and intervention for Intraoperative Hypotension (IOH), a prevalent complication associated with general anesthesia, is crucial to prevent severe postoperative outcomes. While existing machine learning methods for IOH prediction have shown promise, they face limitations such as reliance on single data sources and disregard for crucial features like the trend in Arterial Blood Pressure (ABP) waveforms. To address these challenges, this paper proposes a novel multichannel deep learning framework that combines Convolutional Neural Networks (CNN) and Transformers for automatic IOH prediction. The model leverages four types of physiological waveforms, including ABP, ElectroCardioGram (ECG), photoplethysmography (PLE), and Carbon Dioxide (CO2), to capture both local and global information, enhancing information representation. Experimental results on retrospective data of 14,140 adult patients undergoing non-cardiac surgery from VitalDB, a public data repository of vital signs taken during surgeries in 10 operating rooms at Seoul National University Hospital (from January 6, 2005 to March 1, 2014), demonstrate that the proposed model consistently outperforms other methods, achieving superior AUROC values of 0.943, 0.928, and 0.923 at 5, 10, and 15 minutes before the event, respectively. These results demonstrate the powerfulness of multi-modal data source as well as the importance of ABP waveform trends. Additionally, the incorporation of multi-task learning and the attention mechanism validates the effectiveness and superiority of our model, highlighting its potential for proactive clinical interventions and improved postoperative patient outcomes.

关键词： Analytical models Soft sensors Surgery Predictive models Transformers Market research Data models Biomedical monitoring Monitoring Hypotension

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Dual Attention Poser: Dual Path Body Tracking Based on Attention

Dual Attention Poser: Dual Path Body Tracking Based on Atten...

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2023 IEEE/CVF Conference on Computer Vision and Pattern Recognition Workshops, CVPRW 2023

作者： Di, Xinhan Dai, Xiaokun Zhang, Xinkang Chen, Xinrong Fudan Universiry Academy for Engineering&Technology China Deepearthgo Fudan University Shanghai Key Laboratory of Medical Image Computing and Computer Assisted Intervention China

ISBN: (纸本)9798350302493

Currently, mixed reality head-mounted displays tracking the full body of users is an important human-computer interaction mode through the pose of the head and the hands. Unfortunately, users' virtual representation and experience is limited due to high reconstruction error when simple transformer network architecture is applied. In this paper, we present a novel model, named Dual Attention Poser, which can learn the whole body reconstruction at a high accuracy. The proposed model consists of three key modules. Among them, dual-path attention encoder is designed to extract feature of the sparse signals. Cross attention mixer module enable the fusion of representation in the double path. Attention-gated-mlp decoder is applied to decode the hidden feature from the sparse input through attention gate. Test results on the AMASS dataset show that Dual Attention Poser can reduce the error by up to 18.2% in comparison with the state-of-the-art results. © 2023 IEEE.

关键词： Network architecture

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Air Pollution Monitoring By Integrating Local and Global Information in Self-Adaptive Multiscale Transform Domain

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IEEE Transactions on Multimedia 2025年 27卷 3716-3728页

作者： Gu, Ke Liu, Yuchen Liu, Hongyan Liu, Bo Qiao, Junfei Lin, Weisi Zhang, Wenjun Beijing University of Technology School of Information Science and Technology Engineering Research Center of Intelligent Perception and Autonomous Control of Ministry of Education Beijing Laboratory of Smart Environmental Protection Beijing Key Laboratory of Computational Intelligence and Intelligent System Beijing Artificial Intelligence Institute Beijing100124 China Massey University School of Mathematical and Computational Sciences New Zealand Nanyang Technological University College of Computing and Data Science Singapore Shanghai Jiao Tong University Institute of Image Communication and Information Processing Shanghai China

As the deadliest form of pollution, air pollution had a prolonged severe damage to the human health and life safety of nearly 99% of the world's population. Facing to the problem that billions of tons of pollutants discharged into the air per year by industrial activities, this paper proposed a novel image-based air pollution monitor (IAPM) by incorporating local and global information in the self-adaptive multiscale transform domain, so as to achieve the timely and effective leakage detection of typical air pollutants from a single image. To be specific, this paper first developed a screen-shaped module according to two significant findings in visual neuroscience, which include the high sensitivity of human eyes to horizontal and vertical stimuli and the center-surround inhibition, by designing and fusing the square module, horizontal strip module and vertical strip module parallelly for simulating the behaviour of human eyes to extract local features. Second, the learnable weights and proportional mapping were applied to incorporate the screen-shaped module and lightweight vision transformer as backbone, towards more richly exploiting and fusing local and global information just as the way a brain perceives external stimuli. Third, a new self-adaptive multiscale transform domain method was devised based on two motivations from the visual characteristics of multiscale perception and the brain characteristics of self-adaptive domain transform to modify the backbone by using the operations of pooling and pointwise convolution. Extensive experiments implemented on the datasets of carbon particulate matters and ethylene leakage confirmed the superior monitoring performance of the proposed IAPM model beyond the state-of-the-art (SOTA) peers by an accuracy gain of about 4%. Furthermore, the proposed IAPM model only required 0.089 GFLOPs and 0.15 million model parameters, remarkably outperforming SOTA competitors in computational efficiency and storage resources. © 1999-2

关键词： Information leakage

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An Unsupervised Domain Adaptation Model Based on Multi-Level Joint Alignment for Multi-Modal Cardiac image Segmentation

An Unsupervised Domain Adaptation Model Based on Multi-Level...

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2023 International Conference on Biomimetic Intelligence and Robotics

作者： Li, Jiapeng Lv, Yimou Xu, Lisheng Qi, Lin College of Medicine and Biological Information Engineering Northeastern University Shenyang110169 China Engineering Research Center of Medical Imaging and Intelligent Analysis Ministry of Education Shenyang110169 China Key Laboratory of Medical Image Computing Ministry of Education Northeastern University Shenyang110169 China

Unsupervised Domain Adaptation has greatly boosted the performance of multi-modal medical segmentation when there are only source domain labels and no labels in the target domain. Many previous work relies on Convolutional Neural Networks for distribution or instance alignment, however, the receptive field of CNN makes it overly concerned with texture and local semantic information of images, while losing the global style information and semantic information and lacking relationships between local and global semantics. In order to address these issues, we propose a two-stage, multi-level framework for unsupervised domain adaptation, which consists of an image translation network and a Transformer-based domain adaptation segmentation network, jointly aligning the data distribution in the source and target domains from the image, feature and output level through adversarial learning. Experimental results indicate that our method can achieve satisfactory results and outperform other state-of-the-art medical image segmentation methods. © 2023 The Authors. Published by Elsevier B.V.

关键词： Textures

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Incorporating dynamic attention gating mechanism and pre-trained embedding for Chinese clinical named entity recognition

Incorporating dynamic attention gating mechanism and pre-tra...

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2023 International Conference on Biomimetic Intelligence and Robotics

作者： Qiu, Zhenming Pan, Anyu Qi, Lin College of Medicine and Biological Information Engineering Northeastern University Shenyang110169 China Engineering Research Center of Medical Imaging and Intelligent Analysis Ministry of Education Shenyang110169 China Key Laboratory of Medical Image Computing Ministry of Education Northeastern University Shenyang110169 China

Clinical Named Entity Recognition (CNER) serves as a cornerstone in clinical research and healthcare informatics, with its primary goal being the discernment and categorization of clinical terminologies present within Electronic medical Records (EMRs). While deep learning has significantly improved CNER’s performance, these models still face challenges in identifying rare or unseen entities. Our study unveils an innovative DAGM-BiLSTM-CRF model that seamlessly integrates data-driven deep learning strategies with human knowledge to surmount this limitation. The distinctive features of this model lie in its integration of a pre-trained character embedding layer, adept at encapsulating nuanced semantic variations at the granularity of individual characters. Furthermore, it incorporates a bidirectional Long Short-Term Memory (BiLSTM) layer, proficient in deriving contextually relevant information by traversing the sequence from both endpoints. The most noteworthy aspect of our model is the inclusion of a Dynamic Attention Gating Mechanism (DAGM) that dynamically recalibrates attention weights based on the traits of the input sequence and a Conditional Random Fields (CRF) layer that considers interdependencies among output labels within a sequence. The evaluation was carried out on the CCKS-2017 CNER benchmark dataset to underscore the superiority of our model over existing cutting-edge methods, thereby validating its proficiency in deciphering the intricacies of Chinese electronic medical records. © 2023 The Authors. Published by Elsevier B.V.

关键词： Embeddings

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GDTNet: A Synergistic Dilated Transformer and CNN by Gate Attention for Abdominal Multi-organ Segmentation 30th

GDTNet: A Synergistic Dilated Transformer and CNN by Gate ...

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30th International Conference on MultiMedia Modeling, MMM 2024

作者： Zhang, Can Wang, Zhiqiang Zhang, Yuan Li, Xuanya Hu, Kai Key Laboratory of Intelligent Computing and Information Processing of Ministry of Education Xiangtan University Xiangtan411105 China Key Laboratory of Medical Imaging and Artificial Intelligence of Hunan Province Xiangnan University Chenzhou423000 China Baidu Inc. Beijing100085 China

ISBN: (纸本)9783031533013

As one of the key problems in computer-aided medical image analysis, learning how to model global relationships and extract local details is crucial to improve the performance of abdominal multi-organ segmentation. While current techniques for Convolutional Neural Networks (CNNs) are quite mature, their limited receptive field makes it difficult to balance the ability to capture global relationships with local details, especially when stacked onto deeper networks. Thus, several recent works have proposed Vision Transformer based on a self-attentive mechanism and used it for abdominal multi-organ segmentation. However, Vision Transformer is computationally expensive by modeling long-range relationships on pairs of patches. To address these issues, we propose a novel multi-organ segmentation framework, named GDTNet, based on the synergy of CNN and Transformer for mining global relationships and local details. To achieve this goal, we innovatively design a Dilated Attention Module (DAM) that can efficiently capture global contextual features and construct global semantic information. Specifically, we employ a three-parallel branching structure to model the global semantic information of multiscale encoded features by Dilated Transformer, combined with global average pooling under the supervision of Gate Attention. In addition, we fuse each DAM with DAMs from all previous layers to further encode features between scales. Extensive experiments on the Synapse dataset show that our method outperforms ten other state-of-the-art segmentation methods, achieving accurate segmentation of multiple organs in the abdomen. © The Author(s), under exclusive license to Springer Nature Switzerland AG 2024.

关键词： Computer aided analysis

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Self-supervised fast reconstruction method for diffusion MRI based on multi-directional assistance 17

Self-supervised fast reconstruction method for diffusion MRI...

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17th IEEE International Conference on Signal Processing, ICSP 2024

作者： Wu, Yuxin Zhang, Jian Wang, Lihui Cao, Ying Wu, Linhai Wu, Yunjia Ye, Chen Zhu, Yuemin Guizhou University Key Laboratory of Intelligent Medical Image Analysis and Precise Diagnosis of Guizhou Province Engineering Research Center of Text Computing & Cognitive Intelligence Ministry of Education State Key Laboratory of Public Big Data College of Computer Science and Technology Guiyang China Univ Lyon Insa Lyon Cnrs Inserm Creatis Umr 5220 U1206 France

ISBN: (纸本)9798350387384

Diffusion MRI (dMRI) is widely used for the detection and diagnosis of various pathologies due to its non-invasive nature. However, its signal acquisition process is relatively slow and susceptible to motions. In order to accelerate reconstruction process, many deep learning-based methods have been developed in recent years to achieve promising results, while most of them are supervised based methods and require fully sampled data which are difficult to obtain in practical applications to train the network. Self-supervised based methods were proposed to deal with this problem to a certain extent, however, they are devoted only to conventional MRI data, ignoring the correlation between the directions of dMRI data. To address this issue, we propose a self-supervised fast reconstruction method for dMRI based on multi-directional assistance. The method better utilizes the information between dMRI data directions by Partition-Replace operation, cleverly constructing data pairs and designing effective self-supervised strategy for bi-directional prediction, which can overcome the problem of data incompleteness and guide the model to reconstruct unsampled signals in spite of the difficulty of acquiring fully sampled data. Experimental results show that our method achieves better reconstruction in the absence of fully sampled data, even with an 8-fold acceleration factor. © 2024 IEEE.

关键词： Self-supervised learning

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Penta-Encoder with medical Transformer for Incomplete Multimodal Learning of Brain Tumor Segmentation 17

Penta-Encoder with Medical Transformer for Incomplete Multim...

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17th IEEE International Conference on Signal Processing, ICSP 2024

作者： Yu, Guohui Wang, Lihui Chen, Qijian Wang, Li Tang, Kun Cheng, Xinyu Zhu, Yuemin Guizhou University Key Laboratory of Intelligent Medical Image Analysis and Precise Diagnosis of Guizhou Province Engineering Research Center of Text Computing & Cognitive Intelligence Ministry of Education State Key Laboratory of Public Big Data College of Computer Science and Technology Guiyang China Univ Lyon Insa Lyon Cnrs Inserm Creatis Umr 5220 U1206 Lyon France

ISBN: (纸本)9798350387384

Accurate brain tumor segmentation of magnetic resonance imaging (MRI) images requires the integration of multimodal data in effective collaborative learning. However, clinical scenarios often face missing modalities, significantly impacting segmentation performance. In this paper, we propose the penta-encoder with medical transformer (Penta-MedTrans) for incomplete multimodal learning, which consists of four main components: a modality-specific encoder (MSE), a modality-dynamic encoder (MDE), a multimodal fusion module (MMFM) and a convolutional decoder. The MSE extracts unique features for each modality, while the MDE captures inter-modal semantics to address missing modalities. The MMFM establishes and aligns long-range correlations between modal-invariant features and global semantics of tumor regions. The convolutional decoder generates robust segmentation results by progressively upsampling and fusing modality-invariant features. We extensively validated our method on the BraTS 2020 and BraTS 2021 datasets for brain tumor segmentation. Results showed that our method outperforms SOTA for incomplete multimodal brain tumor segmentation across most subsets. © 2024 IEEE.

关键词： Semantic Segmentation

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