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Mem Brain: An Easy-to-Use Online Webserver for Transmembrane Protein Structure Prediction

Nano-Micro Letters 2018年第1期10卷 12-19页

作者： Xi Yin Jing Yang Feng Xiao Yang Yang Hong-Bin Shen Institute of Image Processing and Pattern Recognition Shanghai Jiao Tong University Key Laboratory of System Control and Information Processing Ministry of Education of China Department of Computer Science Shanghai Jiao Tong University Key Laboratory of Shanghai Education Commission for Intelligent Interaction and Cognitive Engineering

Membrane proteins are an important kind of proteins embedded in the membranes of cells and play crucial roles in living organisms, such as ion channels,transporters, receptors. Because it is difficult to determinate the membrane protein's structure by wet-lab experiments,accurate and fast amino acid sequence-based computational methods are highly desired. In this paper, we report an online prediction tool called Mem Brain, whose input is the amino acid sequence. Mem Brain consists of specialized modules for predicting transmembrane helices, residue–residue contacts and relative accessible surface area of a-helical membrane proteins. Mem Brain achieves aprediction accuracy of 97.9% of ATMH, 87.1% of AP,3.2 ± 3.0 of N-score, 3.1 ± 2.8 of C-score. Mem BrainContact obtains 62%/64.1% prediction accuracy on training and independent dataset on top L/5 contact prediction,respectively. And Mem Brain-Rasa achieves Pearson correlation coefficient of 0.733 and its mean absolute error of13.593. These prediction results provide valuable hints for revealing the structure and function of membrane *** Brain web server is free for academic use and available at ***/bioinf/Mem Brain/.

关键词： Transmembrane a-helices Structure prediction Machine learning Contact map prediction Relative accessible surface area

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Research on a novel restoration algorithm of turbulence-degraded images with alternant iterations

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Journal of Systems Engineering and Electronics 2006年第3期17卷 477-482页

作者： Liu Chunsheng Hong Hanyu Zhang Tianxu Inst. for Pattern Recognition and AI State Key Laboratory of Image Processing and Intelligent Control Huazhong Univ. of Science and Technology Wuhan 430074 P. R. China

A new restoration algorithm based on double loops and alternant iterations is proposed to restore the object image effectively from a few frames of turbulence-degraded images, Based on the double loops, the iterative relations for estimating the turbulent point spread function PSF and object image alternately are derived. The restoration experiments have been made on computers, showing that the proposed algorithm can obtain the optimal estimations of the object and the point spread function, with the feasibility and practicality of the proposed algorithm being convincing.

关键词： turbulence-degraded image image restoration double loops alternant iterations.

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On string languages generated by spiking neural P systems with exhaustive use of rules

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Natural Computing 2008年第4期7卷 535-549页

作者： Zhang, Xingyi Zeng, Xiangxiang Pan, Linqiang Key Laboratory of Image Processing and Intelligent Control Department of Control Science and Engineering Huazhong University of Science and Technology Wuhan 430074 Hubei China

We continue the study of (extended) spiking neural P systems with exhaustive use of rules by considering these computing devices as language generators. Specifically, a step is associated with a symbol according to the number of spikes emitted by the output neuron and the sequence of these symbols associated with a halting computation constitutes a string. Two cases are considered: one of them interprets a step when no spike is emitted as a specified symbol, the other interprets such a step as the empty string. In both cases, it is proved that finite and recursively enumerable languages are characterized by extended spiking neural P systems working in the exhaustive mode. The relationships with regular languages are also investigated. © Springer Science+Business Media B.V. 2008.

关键词： Membrane computing Register machine SN P systems

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control design of 60kW PEMFC generation system for residential applications

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2013年第9期14卷 679-685页

作者： Ying-ying ZHANG Ying ZHANG Xi LI Guang-yi CAO Shandong Provincial Key Laboratory of Ocean Environment Monitoring Technology Institute of Oceanographic Instrumentation Shandong Academy of Sciences Control Science and Engineering Department Key Laboratory of the Ministry of Education for Image Processing and Intelligent Control Huazhong University of Science and Technology Fuel Cell Institute Department of Automation Shanghai Jiao Tong University

This paper presented a control design methodology for a proton exchange membrane fuel cell (PEMFC) generation system for residential applications. The dynamic behavior of the generation system is complex in such applications. A comprehensive control design is very important for achieving a steady system operation and efficiency. The control strategy for a 60 kW generation system was proposed and tested based on the system dynamic model. A two-variable single neuron proportional-integral (PI) decoupling controller was developed for anode pressure and humidity by adjusting the hydrogen flow and water injection. A similar controller was developed for cathode pressure and humidity by adjusting the exhaust flow and water injection. The desired oxygen excess ratio was kept by a feedback controller based on the load current. An optimal seeking controller was used to trace the unique optimal power point. Two negative feedback controllers were used to provide AC power and a suitable voltage for residential loads by a power conditioning unit. control simulation tests showed that 60 kW PEMFC generation system responded well for computer-simulated step changes in the load power demand. This control methodology for a 60 kW PEMFC generation system would be a competitive solution for system level designs such as parameter design, performance analysis, and online optimization.

关键词： Proton exchange membrane fuel cell （PEMFC） Generation system control strategy decoupling control Optimalseeking control

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Consensus in second-order multi-agent systems via impulsive control using position-only information with heterogeneous delays

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IET control Theory and Applications 2015年第3期9卷 336-345页

作者： Wang, Yan-Wu Yi, Jing-Wen School of Automation Huazhong University of Science and Technology Wuhan430074 China Key Laboratory of Image Processing and Intelligent Control Huazhong University of Science AndTechnology Ministry of China China

This study investigates the consensus problem of second-order multi-agent systems (MASs) via impulsive control using position-only information with communication delays. The communication delays between any two distinct agents are different which can be larger than one impulsive period. A distributed impulsive consensus protocol is designed, in which only the delayed sampled relative positions to neighbours and the relative position to the last sampling state are utilised. By introducing some virtual subgraphs and performing three steps of model transformation, the consensus problem of original continuous-time system is converted to the stability problem of a discrete-time expanded error system. Some necessary and sufficient criteria are derived to grantee the dynamic average-consensus of the MAS. Furthermore, a special case, that is, the delays less than one impulsive period, is discussed, and the bounds of impulsive periods for the dynamic average-consensus are obtained in explicit expressions for both the undirected and directed communication graphs, respectively. Two numerical simulation examples are given to illustrate the effectiveness of theoretical results. © 2015 The Institution of Engineering and Technology.

关键词： Multi agent systems

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Improved taboo search algorithm for designing DNA sequences

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Progress in Natural Science:Materials International 2008年第5期18卷 623-627页

作者： Kai Zhang a, Jin Xu a,b, Xiutang Geng a, Jianhua Xiao a, Linqiang Pana, a The key laboratory of image processing and intelligent control, Department of control Science and Engineering, Huazhong University of Science and Technology, Wuhan 430074, China b School of Electronic Engineering and Computer Science, Peking University, Beijing 100871, China The Key Laboratory of Image Processing and Intelligent Control Department of Control Science and Engineering Huazhong University of Science and Technology Wuhan 430074 China School of Electronic Engineering and Computer Science Peking University Beijing 100871 China

The design of DNA sequences is one of the most practical and important research topics in DNA computing. We adopt taboo search algorithm and improve the method for the systematic design of equal-length DNA sequences, which can satisfy certain combinatorial and thermodynamic constraints. Using taboo search algorithm, our method can avoid trapping into local optimization and can nd a set of good DNA sequences satisfying required constraints.

关键词： DNA computing Taboo search algorithm DNA sequence design

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Arithmetic computation using self-assembly of DNA tiles:subtraction and division

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Progress in Natural Science:Materials International 2009年第3期19卷 377-388页

作者： Xuncai Zhang a,b, Yanfeng Wang b, Zhihua Chen a, Jin Xu a,*, Guangzhao Cui b a The key laboratory of image processing and intelligent control, Department of control Science and Engineering, Huazhong University of Science and Technology, Wuhan 430074, China b School of Electrical and Electronic Engineering, Zhengzhou University of Light Industry, Zhengzhou 450002, China [a]The Key Laboratory of Image Processing and Intelligent Control Department of Control Science and Engineering Huazhong University of Science and Technology Wuhan 430074 China [b]School of Electrical and Electronic Engineering Zhengzhou University of Light Industry Zhengzhou 450002 China

Recently, experiments have demonstrated that simple binary arithmetic and logical operations can be computed by the process of self- assembly of DNA tiles. In this paper, we show how the tile assembly process can be used for subtraction and division. In order to achieve this aim, four systems, including the comparator system, the duplicator system, the subtraction system, and the division system, are pro- posed to compute the difference and quotient of two input numbers using the tile assembly model. This work indicates that these systems can be carried out in polynomial time with optimal O(1) distinct tile types in parallel and at very low cost. Furthermore, we provide a scheme to factor the product of two prime numbers, and it is a breakthrough in basic biological operations using a molecular computer by self-assembly.

关键词： Self-assembly Subtractor Divider Tile assembly model DNA tiles DNA computing

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Tracking control of pneumatic muscle using Lyapunov based control method

Tracking control of pneumatic muscle using Lyapunov based co...

引用

2012 International Conference on Modelling, Identification and control, ICMIC 2012

作者： Elobaid, Youssif M. T. Huang, Jian Wang, Yongji Wu, Jun Key Laboratory of Image Processing and Intelligent Control Department of Control Science and Technology Huazhong University of Science and Technology Wuhan China

ISBN: (纸本)9780956715715

Presently pneumatic muscles (PMs) are used in various applications due to their simple construction, lightweight and high force to weight ratio. However, pneumatic muscles are facing various problems due to their nonlinear characteristic in various mechanical applications. The model of PM is nonlinear and time-varying. In this paper, a Lyapunov-based control (LBC) approach is proposed for the control of PM. Based on the nonlinear characteristic of PM, a dynamic model of the PM actuator with pulling a mass against gravity is formed. control objectives are both a regulation and an asymptotic tracking of a desired trajectory. Stability analysis based on Lyapunov method with respect to our proposed control law is discussed. The simulation results show the validity, effectiveness and enhancing robustness of the proposed method. © 2012 Huazhong Univ of Sci & Tec.

关键词： Lyapunov methods

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Passivity-Based Robust control Against Quantified False Data Injection Attacks in Cyber-Physical Systems

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IEEE/CAA Journal of Automatica Sinica 2021年第8期8卷 1440-1450页

作者： Yue Zhao Ze Chen Chunjie Zhou Yu-Chu Tian Yuanqing Qin Key Laboratory of Ministry of Education for Image Processing and Intelligent Control School of Artificial Intelligence and AutomationHuazhong University of Science and TechnologyWuhan 430074China School of Computer Science Queensland University of TechnologyBrisbane QLD 4001Australia

Secure control against cyber attacks becomes increasingly significant in cyber-physical systems(CPSs).False data injection attacks are a class of cyber attacks that aim to compromise CPS functions by injecting false data such as sensor measurements and control *** quantified false data injection attacks,this paper establishes an effective defense framework from the energy conversion ***,we design an energy controller to dynamically adjust the system energy changes caused by unknown *** designed energy controller stabilizes the attacked CPSs and ensures the dynamic performance of the system by adjusting the amount of damping ***,with the disturbance attenuation technique,the burden of control system design is simplified because there is no need to design an attack *** addition,this secure control method is simple to implement because it avoids complicated mathematical *** effectiveness of our control method is demonstrated through an industrial CPS that controls a permanent magnet synchronous motor.

关键词： Cyber-physical systems energy controller energy conversion false data injection attacks L2 disturbance attenuation technology

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An improved estimation of distribution algorithm for multi-compartment electric vehicle routing problem

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Journal of Systems Engineering and Electronics 2021年第2期32卷 365-379页

作者： SHEN Yindong PENG Liwen LI Jingpeng Key Laboratory of Image Processing and Intelligent Control School of Artificial Intelligence and AutomationHuazhong University of Science and TechnologyWuhan 430074China Division of Computing Science and Mathematics University of StirlingStirling FK94LAUK

The multi-compartment electric vehicle routing problem(EVRP)with soft time window and multiple charging types(MCEVRP-STW&MCT)is studied,in which electric multi-compartment vehicles that are environmentally friendly but need to be recharged in course of transport process,are employed.A mathematical model for this optimization problem is established with the objective of minimizing the function composed of vehicle cost,distribution cost,time window penalty cost and charging service *** solve the problem,an estimation of the distribution algorithm based on Lévy flight(EDA-LF)is proposed to perform a local search at each iteration to prevent the algorithm from falling into local *** results demonstrate that the EDA-LF algorithm can find better solutions and has stronger robustness than the basic EDA *** addition,when comparing with existing algorithms,the result shows that the EDA-LF can often get better solutions in a relatively short time when solving medium and large-scale *** experiments show that using electric multi-compartment vehicles to deliver incompatible products can produce better results than using traditional fuel vehicles.

关键词： multi-compartment vehicle routing problem electric vehicle routing problem(EVRP) soft time window multiple charging type estimation of distribution algorithm(EDA) Lévy flight

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