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Author Correction: Genomic footprints of activated telomere maintenance mechanisms in cancer (Dec, 10.1038/s41467-019-13824-9, 2022)

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NATURE COMMUNICATIONS 2022年第1期13卷 1-1页

作者： Sieverling, Lina Hong, Chen Koser, Sandra D. Ginsbach, Philip Kleinheinz, Kortine Hutter, Barbara Braun, Delia M. Cortes-Ciriano, Isidro Xi, Ruibin Kabbe, Rolf Park, Peter J. Eils, Roland Schlesner, Matthias Brors, Benedikt Rippe, Karsten Jones, David T. W. Feuerbach, Lars Division of Applied Bioinformatics German Cancer Research Center (DKFZ) 69120 Heidelberg Germany Faculty of Biosciences Heidelberg University 69120 Heidelberg Germany Division of Applied Bioinformatics German Cancer Research Center (DKFZ) Heidelberg Germany Faculty of Biosciences Heidelberg University Heidelberg Germany Division of Theoretical Bioinformatics German Cancer Research Center (DKFZ) 69120 Heidelberg Germany Department for Bioinformatics and Functional Genomics Institute for Pharmacy and Molecular Biotechnology (IPMB) and BioQuant 69120 Heidelberg Germany Division of Theoretical Bioinformatics German Cancer Research Center (DKFZ) Heidelberg Germany Institute of Pharmacy and Molecular Biotechnology and BioQuant Heidelberg University Heidelberg Germany German Cancer Consortium (DKTK) Heidelberg Germany National Center for Tumor Diseases (NCT) Heidelberg Heidelberg Germany Heidelberg Center for Personalized Oncology (DKFZ-HIPO) German Cancer Research Center (DKFZ) Heidelberg Germany German Cancer Consortium (DKTK) German Cancer Research Center (DKFZ) Heidelberg Germany Division of Chromatin Networks German Cancer Research Center (DKFZ) and BioQuant 69120 Heidelberg Germany Department of Biomedical Informatics Harvard Medical School Boston Massachusetts 02115 USA Department of Chemistry Centre for Molecular Science Informatics University of Cambridge Cambridge CB2 1EW UK Ludwig Center at Harvard Medical School Boston Massachusetts 02115 USA Department of Biomedical Informatics Harvard Medical School Boston MA USA Department of Chemistry Centre for Molecular Science Informatics University of Cambridge Cambridge UK Ludwig Center at Harvard Medical School Boston MA USA School of Mathematical Sciences and Center for Statistical Science Peking University Beijing 100871 China Heidelberg University Heidelberg Germany New BIH Digital Health Center Berlin Institute of Health (BIH) and Charité - Universitätsmedizin Berlin Berlin Germany Bioi

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Changing life expectancy in European countries 1990–2021: a subanalysis of causes and risk factors from the Global Burden of Disease Study 2021

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The Lancet Public Health 2025年第3期10卷 e172-e188页

作者： Steel, Nicholas Bauer-Staeb, Clarissa Maria Mercedes Ford, John A. Abbafati, Cristiana Abdalla, Mohammed Altigani Abdelkader, Atef Abdi, Parsa Zuñiga, Roberto Ariel Abeldaño Abiodun, Olugbenga Olusola Abolhassani, Hassan Abu-Gharbieh, Eman Abukhadijah, Hana J. Abu-Zaid, Ahmed Addo, Isaac Yeboah Addolorato, Giovanni Adekanmbi, Victor Adetunji, Juliana Bunmi Adeyeoluwa, Temitayo Esther Agardh, Emilie E. Agyemang-Duah, Williams Ahmad, Danish Ahmed, Ayman Ahmed, Syed Anees Akinosoglou, Karolina Akkaif, Mohammed Ahmed Al Awaidy, Salah Al Hasan, Syed Mahfuz Al Zaabi, Omar Ali Mohammed Aldridge, Robert W. Algammal, Abdelazeem M. Al-Gheethi, Adel Ali Saeed Ali, Abid Ali, Mohammed Usman Ali, Syed Shujait Ali, Waad Alicandro, Gianfranco Alif, Sheikh Mohammad Al-Jumaily, Adel Allebeck, Peter Alrawashdeh, Ahmad Al-Rifai, Rami H. Alsabri, Mohammed A. Alshahrani, Najim Z. Aluh, Deborah Oyine Al-Wardat, Mohammad Al-Zyoud, Walid A. Amiri, Sohrab Anderlini, Deanna Andrei, Catalina Liliana Anil, Abhishek Anvari, Saeid Anyasodor, Anayochukwu Edward Appiah, Seth Christopher Yaw Aquilano, Michele Arabloo, Jalal Arafat, Mosab Areda, Demelash Aremu, Abdulfatai Armani, Keivan Armocida, Benedetta Ärnlöv, Johan Asaduzzaman, Muhammad Astell-Burt, Thomas Aujayeb, Avinash Ausloos, Marcel Azadnajafabad, Sina Aziz, Shahkaar Azzam, Ahmed Y. Babu, Giridhara Rathnaiah Badache, Andreea Corina Badiye, Ashish D. Bahramian, Saeed Baig, Atif Amin Baker, Jennifer L. Bansal, Hansi Bärnighausen, Till Winfried Barone, Mark Thomaz Ugliara Barrow, Amadou Barteit, Sandra Bashir, Shahid Bashiru, Hameed Akande Basso, João Diogo Bastan, Mohammad-Mahdi Basu, Sanjay Batra, Kavita Bauckneht, Matteo Baune, Bernhard T. Beghi, Massimiliano Beiranvand, Maryam Béjot, Yannick Bell, Michelle L. Bello, Olorunjuwon Omolaja Belo, Luis Beloukas, Apostolos Beneke, Alice A. Bettencourt, Paulo J.G. Bhagavathula, Akshaya Srikanth Bhala, Neeraj Bhaskar, Sonu Bisulli, Francesca Bjørge, Tone Bodunrin, Aadam Olalekan Carvajal, Alejandro Botero Bouaoud, Souad Brayne, Carol Brenner, H Department of Primary Care and Public Health University of East Anglia Norwich United Kingdom Office for Health Improvement and Disparities Department of Health and Social Care London United Kingdom Department of Legal and Economic Studies La Sapienza University Rome Italy Rome Italy Hull York Medical School University of Hull Hull United Kingdom Department of Mathematics and Sciences Ajman University Ajman United Arab Emirates Department of Medicine Memorial University St. John's NL Canada Postgraduate Department University of Sierra Sur Miahuatlan de Porfirio Diaz Mexico Yhteiskuntadatatieteen keskus (Centre for Social Data Science) Helsinki Finland Department of Internal Medicine Federal Medical Centre Abuja Nigeria Research Center for Immunodeficiencies Tehran University of Medical Sciences Tehran Iran Department of Medical Biochemistry and Biophysics Karolinska Institutet (Karolinska Institute) Stockholm Sweden Department of Clinical Sciences University of Sharjah Sharjah United Arab Emirates Department of Biopharmaceutics and Clinical Pharmacy University of Jordan Amman Jordan Medical Research Center Hamad Medical Corporation Doha Qatar Department of Biochemistry and Molecular Medicine Alfaisal University Riyadh Saudi Arabia College of Graduate Health Sciences University of Tennessee Memphis TN United States School of Medicine Sydney NSW Australia Centre for Social Research in Health University of New South Wales Sydney NSW Australia Internal Medicine and Alcohol Related Disease Unit Fondazione Policlinico Universitario A. Gemelli IRCCS Rome Italy Department of Medical and Surgical Sciences Università Cattolica di Roma (Catholic University of Rome) Rome Italy Department of Obstetrics and Gynecology University of Texas Medical Branch Galveston TX United States Department of Biochemistry Osun State University Osogbo Nigeria Department of Pharmacology and Therapeutics University of Medical Sciences Ondo Ondo Nigeria Department of Veteri

Background: Decades of steady improvements in life expectancy in Europe slowed down from around 2011, well before the COVID-19 pandemic, for reasons which remain disputed. We aimed to assess how changes in risk factors and cause-specific death rates in different European countries related to changes in life expectancy in those countries before and during the COVID-19 pandemic. Methods: We used data and methods from the Global Burden of Diseases, Injuries, and Risk Factors Study 2021 to compare changes in life expectancy at birth, causes of death, and population exposure to risk factors in 16 European Economic Area countries (Austria, Belgium, Denmark, Finland, France, Germany, Greece, Iceland, Ireland, Italy, Luxembourg, the Netherlands, Norway, Portugal, Spain, and Sweden) and the four UK nations (England, Northern Ireland, Scotland, and Wales) for three time periods: 1990–2011, 2011–19, and 2019–21. Changes in life expectancy and causes of death were estimated with an established life expectancy cause-specific decomposition method, and compared with summary exposure values of risk factors for the major causes of death influencing life expectancy. Findings: All countries showed mean annual improvements in life expectancy in both 1990–2011 (overall mean 0·23 years [95% uncertainty interval [UI] 0·23 to 0·24]) and 2011–19 (overall mean 0·15 years [0·13 to 0·16]). The rate of improvement was lower in 2011–19 than in 1990–2011 in all countries except for Norway, where the mean annual increase in life expectancy rose from 0·21 years (95% UI 0·20 to 0·22) in 1990–2011 to 0·23 years (0·21 to 0·26) in 2011–19 (difference of 0·03 years). In other countries, the difference in mean annual improvement between these periods ranged from –0·01 years in Iceland (0·19 years [95% UI 0·16 to 0·21] vs 0·18 years [0·09 to 0·26]), to –0·18 years in England (0·25 years [0·24 to 0·25] vs 0·07 years [0·06 to 0·08]). In 2019–21, there was an overall decrease in mean annual life expectancy a

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When function mirrors structure: how slow waves are shaped by cortical layers

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BMC Neuroscience 2015年第1期16卷 1-2页

作者： Cristiano Capone Paolo Del Giudice Maurizio Mattia Beatriz Rebollo Maria Victoria Sanchez-Vives Alberto Muñoz-Cespédes PhD Program in Physics Sapienza University Rome Italy Istituto Superiore di Sanità Rome Italy IDIBAPS Barcelona Spain ICREA Barcelona Spain Universidad Complutense de Madrid Madrid Spain

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Triaxial MMG investigation during FES-induced cycle movements

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Journal of physics: Conference Series 2016年第1期705卷

作者： M C Gelain G N Nogueira-Neto P Nohama P M Gewehr Master's student of Electrical Engineering and Industrial Informatics at UTFPR (Rehabilitation engineering laboratory phone: +55 (41) 3310-4489) Brazil PhD in Biomedical Engineering researcher and professor of Computer Engineering at Pontifícia Universidade Católica do Paraná (PUCPR) Brazil PhD in Biomedical Engineering researcher and full professor at the PPGTS stricto sensu program at Pontifícia Universidade Católica do Paraná (PUCPR) Brazil PhD in Medical Physics Bioengineering and professor of Biomedical engineering at UTFPR Brazil

Spinal cord injury is damage to the spinal cord that results in loss of functions, causes muscle, joint and bone deficits, moreover it increases the muscle tone level. FEScycling is an alternative rehabilitation process to conserve the musculoskeletal system affected by the injury in the functional state. The aim of this study is to get the legs bilaterally synchronized by FES and compare MMG signal responses. The preliminary protocol consists of five consecutive contractions. The first and the last contractions were discarded and the three intermediate contractions were analyzed. A ratio between MMG values of muscle responses during propulsion and return of pedalling phases was calculated for each cycle and each leg. The applied FES profile consisted of pulse and burst on time of 250 us and 5 ms and frequencies of 1000 Hz and 20 Hz, respectively. Results showed that greater MMG RMS values tend to occur during the propulsion phase than in the return phase. MMG Z axis of RLL and MMG X axis of LLL were the axes that presented the greatest ratios. The MMG RMS signal showed that greater values tend to occur during the propulsion phase than in the return phase of the same thigh.

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26th Annual Computational Neuroscience Meeting (CNS*2017) of the Organization for Computational Neuroscience Antwerp, Belgium, July 15-20, 2017

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BMC NEUROSCIENCE 2017年第SUPPL 1期18卷 59-59页

作者： [Anonymous] Indiana University Purdue University Indianapolis Indianapolis IN 46032 USA Stark Neurosciences Research Institute Indiana University School of Medicine Indianapolis IN 46032 USA Department of Mathematics East Carolina University Greenville NC 27858 USA Jülich Supercomputing Centre Forschungszentrum Jülich 52425 Jülich Germany Future Systems Swiss National Supercomputing Centre 8092 Zurich Switzerland User Engagement and Support Swiss National Supercomputing Centre 6900 Lugano Switzerland Institut de Neurosciences des Systèmes Aix Marseille Univ 13005 Marseille France Simulation Lab Neuroscience Forschungszentrum Jülich Jülich Germany Department of Experimental Psychology Ghent University 9000 Ghent Belgium Donders Center for Cognitive Neuroimaging Radboud University 6525HR Nijmegen The Netherlands Department of Electrical Computer and Energy Engineering University of Colorado Boulder CO 80309 USA Department of Neurosurgery Johns Hopkins School of Medicine Baltimore MD 21287 USA Department of Neurology Johns Hopkins School of Medicine Baltimore MD 21287 USA Department of Otolaryngology Johns Hopkins School of Medicine Baltimore MD 21287 USA INSERM U968 Paris France Sorbonne Universités UPMC University Paris 06 UMR_S 968 Institut de la Vision Paris France CNRS UMR_7210 Paris France Department of Computer Architecture and Technology University of Granada (CITIC) Granada Spain Sorbonne Universités UPMC Univ Paris 06 INSERM CNRS Institut de la Vision Paris France Department of Adaptive Machine Systems Osaka University Osaka Japan Department of Computer Science University of Cergy-Pontoise Cergy-Pontoise France Department of Physics and Astronomy College of Charleston Charleston SC 29424 USA School of Physics Faculty of Science University of Sydney Sydney NSW 2006 Australia Center of Excellence for Integrative Brain Function Australian Research Council Sydney Australia Max Planck Institute for Human Cognitive and Brain Sciences Saxony Lei

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A Questionnaire on Materialisms

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OCTOBER 2016年第155期 3-110页

作者： [Anonymous] EMILY APTER is Chair of the Department of Comparative Literature at NYU and coeditor of the Dictionary of Untranslatables: A Philosophical Lexicon (Princeton 2014). ED ATKINS is an artist who lives in Berlin. ARMEN AVANESSIAN is a philosopher and the editor-in-chief at Merve Verlag Berlin founder of . BILL BROWN author of “Thing Theory” (Critical Inquiry 28 Autumn 2001) and Other Things (Chicago 2015) teaches at the University of Chicago. GIULIANA BRUNO is Emmet Blakeney Gleason Professor of Visual and Environmental Studies at Harvard University. JULIA Bryan-Wilson is Associate Professor of Contemporary Art at UC Berkeley. D. GRAHAM BURNETT writes and makes things. He teaches at Princeton and is an editor at Cabinet. MEL Y. CHEN is Associate Professor of Gender and Women's Studies at UC Berkeley and the author of Animacies (Duke 2012). ANDREW COLE is professor of English and director of the Gauss Seminars at Princeton University. His most recent book is The Birth of Theory (Chicago 2014). CHRISTOPH COX is Professor of Philosophy at Hampshire College. SUHAIL MALIK is co-director of MFA Fine Art Goldsmiths London and author of On the Necessity of Art's Exit from Contemporary Art (Urbanomic 2016). T. J. DEMOS is Professor in the Department of the History of Art and Visual Culture University of California Santa Cruz and Director of its Center for Creative Ecologies. JEFF DOLVEN teaches English at Princeton University and is an editor-at-large at Cabinet magazine. DAVID T. DORIS is Associate Professor at the University of Michigan directly above the center of the Earth. He wrote Vigilant Things (Washington 2011). HELMUT DRAXLER is professor for Art Theory at the University of Applied Arts in Vienna. PATRICIA FALGUIÈRES is a professor at the École des Hautes Études en Sciences Sociales (EHESS) Paris. PETER GALISON is the Joseph Pellegrino University Professor in History of Science and Physics at Harvard University. ALEXANDER R. GALLOWAY teaches media theory at New York University. RACHEL HAIDU is Asso

Recent philosophical tendencies of Actor-Network Theory, Object-Oriented Ontology, and Speculative Realism have profoundly challenged the centrality of subjectivity in the humanities, and many artists and curators, particularly in the UK, Germany, and the United States, appear deeply influenced by this shift from epistemology to ontology. October editors asked artists, historians, and philosophers invested in these projectsfrom Graham Harman and Alexander R. Galloway to Armen Avanessian and Patricia Falguieres to Ed Atkins and Amie Siegelto explore what the rewards and risks of assigning agency to objects may be, and how, or if, such new materialisms can be productive for making and thinking about art today.

关键词： Objectivity in art Materialism Art & society

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Conditions of the fuzzy internet mortgage market submodels implementation

Frontiers in Artificial Intelligence and Applications

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Frontiers in Artificial Intelligence and Applications 2012年 243卷 1470-1479页

作者： Orlowski, Aleksander Szczerbicki, Edward Gdansk University of Technology Faculty of Applied Physics Mathematics PhD Program Poland Gdansk University of Technology Faculty of Management and Economics Poland

ISBN: (纸本)9781614991045

The paper introduces some challenges of the fast growing mortgage market in Poland, being also the next step of research presented in previous publications, showing the complete process of building and verifying three submodels for the internet mortgage market. The sub-models are described for three market situations, i.e. stable market, crisis, and boom, then the variables within the models are analyzed statistically (e.g. correlation level) and finally the models are verified. The paper presents the process of verification of submodel nr 3 (fast growing market) as an example of the verification process that was applied. The paper concludes with directions for further research in this area leading to the ultimate application of the proposed model in a real life prognosis process. © 2012 The authors and IOS Press. All rights reserved.

关键词： Fuzzy logic

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Characteristics of Leachate at Sukawinatan Landfill, Palembang, Indonesia

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Journal of physics: Conference Series 2013年第1期423卷

作者： Eka Sri Yusmartini Dedi Setiabudidaya Ridwan Marsi Faizal PhD Candidate Postgraduate Program Sriwijaya University Indonesia Department of Physics Faculty of Mathematics and Science Sriwijaya University Indonesia Nuclear Industrial Materials Technology Centre Serpong Indonesia Faculty of Agriculture Sriwijaya University Indonesia Department of Chemical Engineering Faculty of Engineering Sriwijaya University Indonesia

Landfill (TPA) Sukawinatan Palembang is an open dumping system which covers an area of 25 hectares. This system may bring an environmental damage to the surrounding area because it does not provide leachate treatment. Leachate is the landfill waste that dissolves many compounds that contain pollutants from both organic substances and heavy metal origin. This paper presents the results of laboratory analysis on samples of leachate as well as shallow groundwater from the surrounding area. The results were compared to established quality standards to evaluate whether the leachate has influenced the quality of the shallow groundwater in the surrounding area. The results show that there are some indications that the quality of groundwater has been polluted by the leachate of both organic substances and heavy metals produced by the Sukawinatan landfill.

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Simultaneous Photoacoustic Detection of Red Blood Cell Aggregation and Oxygenation

Simultaneous Photoacoustic Detection of Red Blood Cell Aggre...

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IEEE International Ultrasonics Symposium

作者： Eno Hysi Ratan K. Saha Michael C. Kolios Department of Physics Ryerson University Toronto ON. Canada. He is now at the Louisiana State University School of Medicine MD-PhD Program New Orleans LA. USA Applied Material Science Division Saha Institute of Nuclear Physics Kolkata India Department of Physics Ryerson University Toronto ON. Canada

ISBN: (纸本)9781467345613

Red blood cell (RBC) aggregation is a reversible process which occurs in the presence of increased plasma fibrinogen concentration and low flow conditions. It results in the RBCs forming structures that resemble "stacks of coins" and/or clusters impairing blood flow and the ability of oxygen to diffuse to surrounding tissues. We investigate the use of photoacoustics (PA) to detect and monitor RBC aggregation and the effect of aggregation on the sample oxygenation level. In this study, porcine RBCs were illuminated at 750nm and 1064 nm and the oxygen saturation of each sample was estimated. Aggregation was induced by varying the concentration of Dextran-70. Changes in the photoacoustic signal strength suggest that in the presence of RBC aggregates, the release of oxygen into the surroundings is impaired. A 30% increase in oxygen saturation was measured based on changes in the PA signal when comparing the non-aggregated and aggregated blood samples. This work demonstrates that PA imaging has the potential to detect changes due to RBC aggregation and monitor oxygenation level.

关键词： Photoacoustics Red Blood Cell Aggregation Oxygen Saturation

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Corrigendum: Rapid and highly sensitive detection of Enterovirus 71 by using nanogold-enhanced electrochemical impedance spectroscopy

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Nanotechnology 2013年第39期24卷

作者： Hsing-Yuan Li Shing-Hua Tseng Tsai-Mu Cheng Hsueh-Liang Chu Yu-Ning Lu Fang-Yu Wang Li-Yun Tsai Juo-Yu Shieh Jyh-Yuan Yang Chien-Chang Juan Lung-Chen Tu Chia-Ching Chang Department of Biological Science and Technology National Chiao Tung University Hsinchu Taiwan Department of Pediatrics National Taiwan University Hospital Hsinchu Branch Hsinchu Taiwan The PhD Program for Translational Medicine Taipei Medical University and Academia Sinica Taiwan Institute of Biomedical Sciences Academia Sinica Taiwan Department of Health Research and Diagnostic Center Centers for Disease Control Taipei Taiwan Department of Pediatrics National Yang-Ming University School of Medicine Ilan branch Taiwan Department of Plastic Surgery Mackay Memorial Hospital Taipei Taiwan Institute of Physics Academia Sinica Taiwan

The full text of this article is available in the PDF provided.

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