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检索条件"机构=The PhD program in Biochemistry"
69 条 记 录,以下是1-10 订阅
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Teaching Green Chemistry Through Student-Generated Open Educational Resources
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Journal of College Science Teaching 2023年 第4期52卷 3-5页
作者: Grieger, Krystal Leontyev, Alexey Department of Chemistry and Biochemistry North Dakota State University in Fargo ND United States Department of Chemistry and Biochemistry and Discipline-Based Education Research PhD Program North Dakota State University Fargo ND United States
This article describes the implementation of a student-generated open educational resource project into a majors ’ organic chemistry laboratory. This scaffolded semester-long project was organized into six phases and...
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Variations in kinase and effector signaling logic in a bacterial two component signaling network
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Journal of Biological Chemistry 2025年 第6期301卷 108534页
作者: Swingle, Danielle Epstein, Leah Aymon, Ramisha Isiorho, Eta A. Abzalimov, Rinat R. Favaro, Denize C. Gardner, Kevin H. Structural Biology Initiative CUNY Advanced Science Research Center New YorkNY United States PhD. Program in Biochemistry The Graduate Center – City University of New York New YorkNY United States Department of Chemistry and Biochemistry City College of New York New YorkNY United States PhD. Programs in Biochemistry Biology and Chemistry The Graduate Center – City University of New York New YorkNY United States
The general stress response (GSR) protects bacteria from a wide range of stressors. In Alphaproteobacteria, GSR activation is coordinated by HWE/HisKA2 family histidine kinases (HKs), which can exhibit noncanonical st... 详细信息
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Taming Multiple Binding Poses in Alchemical Binding Free Energy Prediction: the β-cyclodextrin Host-Guest SAMPL9 Blinded Challenge
arXiv
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arXiv 2023年
作者: Khuttan, Sheenam Azimi, Solmaz Wu, Joe Z. Dick, Sebastian Wu, Chuanjie Xu, Huafeng Gallicchio, Emilio Department of Chemistry Brooklyn College The City University of New York United States PhD Program in Biochemistry Graduate Center of the City University of New York United States PhD Program in Chemistry Graduate Center of the City University of New York United States Roivant Sciences New YorkNY United States
We apply the Alchemical Transfer Method (ATM) and a bespoke fixed partial charge force field to the SAMPL9 bCD host-guest binding free energy prediction challenge that comprises a combination of complexes formed betwe... 详细信息
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DNA-damage-associated protein co-expression network in cardiomyocytes informs on tolerance to genetic variation and disease
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iScience 2025年 第5期28卷
作者: Johnson, Omar Darrel Paul, Sayan Gutiérrez, José Angel Russell, William Kent Ward, Michelle Claire Biochemistry Cellular and Molecular Biology Graduate Program University of Texas Medical Branch Galveston 77555 TX United States MD-PhD Combined Degree Program University of Texas Medical Branch Galveston 77555 TX United States Department of Biochemistry and Molecular Biology University of Texas Medical Branch Galveston 77555 TX United States
Cardiovascular disease (CVD) is associated with genetic variants and environmental factors. A consequence of multiple risk factors is DNA damage. To examine how DNA damage influences the cardiomyocyte proteome and its... 详细信息
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Kinetics of primary mechanochemical covalent-bond-forming reactions
RSC Mechanochemistry
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RSC Mechanochemistry 2024年 第1期1卷 11-32页
作者: Yerzhan S. Zholdassov Ryan W. Kwok Milan A. Shlain Monil Patel Mateusz Marianski Adam B. Braunschweig Advanced Science Research Center at the Graduate Center of the City University of New York 85 St Nicholas Terrace New York NY 10031 USA abraunschweig@gc.cuny.edu Department of Chemistry Hunter College 695 Park Ave New York NY 10065 USA PhD Program in Chemistry Graduate Center of the City University of New York 365 5th Ave New York NY 10016 USA PhD Program in Biochemistry Graduate Center of the City University of New York 365 5th Ave New York NY 10016 USA
Mechanical activation of reactions can reduce significantly the amounts of solvent and energy required to form covalent organic bonds. Despite growing interest in the field of mechanochemistry and increasing reports o...
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A good gut feeling on Sarml-mediated axon degeneration
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Protein & Cell 2021年 第8期12卷 596-598页
作者: Victoria E.von Saucken David J.Simon Department of Biochemistry Weill Cornell Medical College1300 York AvenueNew YorkNY 10065USA Tri-lnstitutional MD-PhD Program Weill Cornell MedicineRockefeller UniversityMemorial Sloan Kettering Cancer Center1300 York AvenueNew YorkNY 10065USA
Axons,the cable-like projections of neurons,experience a wide range of stressors throughout their *** result of any one of these challenges can be catastrophic,promoting degeneration of the *** degeneration is an acti... 详细信息
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Enhancing Protein-Ligand Binding Affinity Predictions using Neural Network Potentials
arXiv
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arXiv 2024年
作者: Zariquiey, Francesc Sabanés Galvelis, Raimondas Gallicchio, Emilio Chodera, John D. Markland, Thomas E. De Fabritiis, Gianni C Dr. Aiguader 88 Barcelona08003 Spain Acellera Labs C Dr Trueta 183 Barcelona08005 Spain Department of Chemistry Brooklyn College of the City University of New York PhD Program in Chemistry Graduate Center of the City University of New York PhD Program in Biochemistry Graduate Center of the City University of New York NY11210 United States Computational and Systems Biology Program Sloan Kettering Institute Memorial Sloan Kettering Cancer Center New YorkNY10065 United States Department of Chemistry Stanford University 337 Campus Drive StanfordCA94305 United States Passeig Lluis Companys 23 Barcelona08010 Spain
This letter gives results on improving protein-ligand binding affinity predictions based on molecular dynamics simulations using machine learning potentials with a hybrid neural network potential and molecular mechani... 详细信息
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Mechanistic insights of evaporation-induced actuation in supramolecular crystals (Sept, 10.1038/s41563-020-0799-0, 2020)
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NATURE MATERIALS 2021年 第3期20卷 434-434页
作者: Piotrowska, Roxana Hesketh, Travis Wang, Haozhen Martin, Alan R. G. Bowering, Deborah Zhang, Chunqiu Hu, Chunhua T. McPhee, Scott A. Wang, Tong Park, Yaewon Singla, Pulkit McGlone, Thomas Florence, Alastair Tuttle, Tell Ulijn, Rein V. Chen, Xi Advanced Science Research Center (ASRC) at the Graduate Center of the City University of New York New York NY USA PhD Program in Chemistry The Graduate Center of the City University of New York New York NY USA Department of Pure and Applied Chemistry University of Strathclyde Glasgow UK PhD Program in Physics The Graduate Center of the City University of New York New York NY USA EPSRC Continuous Manufacturing and Crystallisation Future Research Hub c/o Strathclyde Institute of Pharmacy and Biomedical Sciences Technology Innovation Centre University of Strathclyde Glasgow UK Department of Chemistry New York University New York NY USA Department of Chemistry and Biochemistry Hunter College City University of New York New York NY USA Department of Chemical Engineering The City College of New York New York NY USA
A Correction to this paper has been published: https://***/10.1038/s41563-021-00950-3.
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Validation of the Alchemical Transfer Method for the Estimation of Relative Binding Affinities of Molecular Series
arXiv
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arXiv 2023年
作者: Zariquiey, Francesc Sabanés Pérez, Adrià Majewski, Maciej Gallicchio, Emilio De Fabritiis, Gianni C Dr. Aiguader 88 Barcelona08003 Spain Acellera Labs C Dr Trueta 183 Barcelona08005 Spain Department of Chemistry Brooklyn College of the City University of New York PhD Program in Chemistry Graduate Center of the City University of New York PhD Program in Biochemistry Graduate Center of the City University of New York United States Acellera Devonshire House 582 Honeypot Lane Stanmore Middlesex HA7 1JS United Kingdom Passeig Lluis Companys 23 Barcelona08010 Spain
The accurate prediction of protein-ligand binding affinities is crucial for drug discovery. Alchemical free energy calculations have become a popular tool for this purpose. However, the accuracy and reliability of the... 详细信息
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Directed discovery of high-loading nanoaggregates enabled by drug-matched oligo-peptide excipients
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Chem 2025年
作者: Berisha, Naxhije Farahpour, Atena Ramakrishnan, Maithreyi Chen, Chen McPhee, Scott A. Wang, Tong Li, Tai-De Hema, Kuntrapakam Panagiotakopoulou, Magdalini Athiyarath, Vignesh Coste, Maeva Marciano, Yaron Sherman, Emmet Ulijn, Rein V. Heller, Daniel A. Nanoscience Initiative Advanced Science Research Center CUNY Graduate Center City University of New York New York 10031 NY United States Department of Chemistry and Biochemistry Hunter College City University of New York New York 10065 NY United States PhD Program in Chemistry CUNY Graduate Center City University of New York New York 10016 NY United States Molecular Pharmacology Program Memorial Sloan Kettering Cancer Center New York 10065 NY United States Tri-Institutional PhD Program in Chemical Biology Memorial Sloan Kettering Cancer Center New York 10065 NY United States Department of Physics City College of New York City University of New York New York 10031 NY United States Department of Chemistry Brooklyn College City University of New York 2900 Bedford Avenue Brooklyn 11210 NY United States PhD Program in Biochemistry CUNY Graduate Center City University of New York New York 10016 NY United States Weill Cornell Medicine Cornell University New York 10065 NY United States
Nanoparticles can improve drug pharmacokinetics, but low loading efficiencies can limit treatment efficacy. Drug-aggregation-based nanoparticles have demonstrated improved loadings of up to 90%, but few excipients fac... 详细信息
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