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Graph Convolutional Network-based Functional-structural Sub-region Framework for Head and Neck Cancer Prognosis with PET/CT Imaging

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Graph Convolutional Network-based Functional-structural Sub-...

IEEE Symposium on Nuclear Science (NSS/MIC)

作者： Zidong Zhou Junyi Peng Guoyu Lin Huiqin Wu Wenbing Lv Lijun Lu School of Biomedical Engineering Guangdong Province Engineering Laboratory for Medical Imaging and Diagnostic Technology Southern Medical University Guangdong Provincial Key Laboratory of Medical Image Processing Guangzhou China School of Information Science and Engineering Yunnan University Kunming China Pazhou Lab Guangzhou China

In order to improve the behavior of the prognostic model for patients with head and neck cancer (HNC), we constructed a graph convolutional network (GCN), characterizing the interaction of functional and structural information among different sub-regions of tumors in both PET and CT images. Sub-regions were obtained by using the Watershed-based method and were regarded as vertexes in the graph. The element of 1 in the adjacency matrix indicates corresponding two vertices are spatially contiguous, while the element of 0 indicates they are separated. The selected radiomics features were used to characterize each vertex. 642 HNC patients from 8 different centers were used. The best C-index of 0.767 was achieved by the combination of GCN and clinical parameters compared to the radiomics model (0.747) or GCN model (0.702). the proposed approach has great potential in aiding treatment decision-making.

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A MULTI-SCALE SPATIAL TRANSFORMER U-NET FOR SIMULTANEOUSLY AUTOMATIC REORIENTATION AND SEGMENTATION OF 3D NUCLEAR CARDIAC imageS

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arXiv 2023年

作者： Ni, Yangfan Zhang, Duo Ma, Gege Lu, Lijun Huang, Zhongke Zhu, Wentao Research Center for Human-Machine Augmented Intelligence Zhejiang Lab Hangzhou China School of Biomedical Engineering and Guangdong Provincial Key Laboratory of Medical Image Processing Southern Medical University Guangzhou China Department of Nuclear Medicine Sir Run Run Shaw Hospital Hangzhou China

Accurate reorientation and segmentation of the left ventricular (LV) is essential for the quantitative analysis of myocardial perfusion imaging (MPI), in which one critical step is to reorient the reconstructed transaxial nuclear cardiac images into standard short-axis slices for subsequent image processing. Small-scale LV myocardium (LV-MY) region detection and the diverse cardiac structures of individual patients pose challenges to LV segmentation operation. To mitigate these issues, we propose an end-to-end model, named as multi-scale spatial transformer UNet (MS-ST-UNet), that involves the multi-scale spatial transformer network (MSSTN) and multi-scale UNet (MSUNet) modules to perform simultaneous reorientation and segmentation of LV region from nuclear cardiac images. The proposed method is trained and tested using two different nuclear cardiac image modalities: 13N-ammonia PET and 99mTc-sestamibi SPECT. We use a multi-scale strategy to generate and extract image features with different scales. Our experimental results demonstrate that the proposed method significantly improves the reorientation and segmentation performance. This joint learning framework promotes mutual enhancement between reorientation and segmentation tasks, leading to cutting edge performance and an efficient image processing workflow. The proposed end-to-end deep network has the potential to reduce the burden of manual delineation for cardiac images, thereby providing multimodal quantitative analysis assistance for physicists. Copyright © 2023, The Authors. All rights reserved.

关键词： Ammonia

A hierarchical image matting model for blood vessel segmentation in fundus images

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arXiv 2017年

作者： Fan, Zhun Lu, Jiewei Li, Wenji Wei, Caimin Huang, Han Cai, Xinye Chen, Xinjian Guangdong Provincial Key Laboratory of Digital Signal and Image Processing College of Engineering Shantou University Shan'tou515063 China Department of Mathematics Shantou University Shan'tou515063 China School of Software Engineering South China University of Technology Guang'zhou510006 China College of Computer Science and Technology Nanjing University of Aeronautics and Astronautics Jiang'su210016 China Medical Image Processing and Analysis Lab School of Electronics and Information Engineering Soochow University Su'zhou215006 China

In this paper, a hierarchical image matting model is proposed to extract blood vessels from fundus images. More specifically, a hierarchical strategy utilizing the continuity and extendibility of retinal blood vessels is integrated into the image matting model for blood vessel segmentation. Normally the matting models require the user specified trimap, which separates the input image into three regions manually: the foreground, background and unknown regions. However, since creating a user specified trimap is a tedious and time-consuming task, region features of blood vessels are used to generate the trimap automatically in this paper. The proposed model has low computational complexity and outperforms many other state-of-art supervised and unsupervised methods in terms of accuracy, which achieves a vessel segmentation accuracy of 96.0%, 95.7% and 95.1% in an average time of 10.72s, 15.74s and 50.71s on images from three publicly available fundus image datasets DRIVE, STARE, and CHASE_DB1, respectively. Copyright © 2017, The Authors. All rights reserved.

关键词： Blood vessels

Efficient spatialtemporal context modeling for action recognition?

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arXiv 2021年

作者： Cao, Congqi Lu, Yue Zhang, Yifan Jiang, Dongmei Zhang, Yanning Natl. Engineering Laboratory for Integrated Aero-Space-Ground-Ocean Big Data Application Technology Shaanxi Provincial Key Lab on Speech and Image Information Processing School of Computer Science Northwestern Poly-technical University Xi'an710129 China National Laboratory of Pattern Recognition Institute of Automation Chinese Academy of Sciences University of Chinese Academy of Sciences Beijing100190 China

Contextual information plays an important role in action recognition. Local operations have difficulty to model the relation between two elements with a long-distance interval. However, directly modeling the contextual information between any two points brings huge cost in computation and memory, especially for action recognition, where there is an additional temporal dimension. Inspired from 2D criss-cross attention used in segmentation task, we propose a recurrent 3D criss-cross attention (RCCA-3D) module to model the dense long-range spatiotemporal contextual information in video for action recognition. The global context is factorized into sparse relation maps. We model the relationship between points in the same line along the direction of horizon, vertical and depth at each time, which forms a 3D criss-cross structure, and duplicate the same operation with recurrent mechanism to transmit the relation between points in a line to a plane finally to the whole spatiotemporal space. Compared with the non-local method, the proposed RCCA-3D module reduces the number of parameters and FLOPs by 25% and 30% for video context modeling. We evaluate the performance of RCCA-3D with two latest action recognition networks on three datasets and make a thorough analysis of the architecture, obtaining the optimal way to factorize and fuse the relation maps. Comparisons with other state-of-the-art methods demonstrate the effectiveness and efficiency of our model. Copyright © 2021, The Authors. All rights reserved.

关键词： Machine learning

FULL-LENGTH-BODY CBCT IMAGING IN UPRIGHT POSITION WITH ROBOTIC-ARM SYSTEM: A SIMULATION STUDY

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arXiv 2023年

作者： Lin, Tong Lyu, Tianling Wu, Zhan Xi, Yan Zhu, Wentao Chen, Yang Laboratory of Image Science and Technology Southeast University Nanjing China Research Center of Augmented Intelligence Zhejiang Lab Hangzhou China Shanghai First-Imaging Tech Shanghai China Jiangsu Provincial Joint International Research Laboratory of Medical Information Processing Southeast University Nanjing China Key Laboratory of New Generation Artificial Intelligence Technology and Its Interdisciplinary Applications Southeast University Nanjing China

Upright position CT scans make it possible for full-length-body imaging at conditions more relevant to daily situations, but the substantial weight of the upright CT scanners increases the risks to floor’s stability and patients’ safety. Robotic-arm CBCT systems are supposed to be a better solution for this task, but such systems still face challenges including long scanning time and low reconstruction quality. To address the above challenges, this paper proposes a novel method to calculate optimal scanning pitch based on data completeness analysis, which can complete the whole-body scan in the shortest time without a significant decline in image quality. Besides, an FDK-style reconstruction method based on normalized projections is proposed to obtain fast image reconstruction. Extensive experiments prove the effectiveness of the proposed optimal scanning trajectory. Qualitative and quantitative comparisons with FDK and iterative algorithms show that the proposed reconstruction method can obtain high imaging quality with reasonable computation costs. The method proposed in this paper is expected to promote the application of robotic-arm CBCT systems in orthopedic functional analysis. © 2023, CC BY-NC-SA.

关键词： Robotic arms

Intra-Guided Dual-Energy Material Decomposition Method for Dual-Source CBCT Systems

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Intra-Guided Dual-Energy Material Decomposition Method for D...

Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)

作者： Xinyun Zhong Tianling Lyu Zhan Wu Wei Gao Yan Xi Wei Zhao Wentao Zhu Yang Chen Laboratory of Image Science and Technology School of Computer Science and Engineering Southeast University Nanjing China Zhejiang Lab Hangzhou China First-Imaging Tech. Shanghai China Beihang University Beijing China Jiangsu Provincial Joint International Research Laboratory of Medical Information Processing Key Laboratory of New Generation Artificial Intelligence Technology and Its Interdisciplinary Applications Southeast University Nanjing China

ISBN: (数字)9798350371499

ISBN: (纸本)9798350371505

Dual-energy CBCT imaging plays a crucial role in advanced imaging applications due to its ability to quantify material components. Although there are multiple established systems for dual-energy imaging, they often come with high deployment costs. This study investigates the feasibility of dual-energy material decomposition on a less expensive dual-source CBCT system. Due to the specific geometry of dual-source CBCT, cone-beam (CB) artifacts seriously degrade the material decomposition quality when the direct inversion method is adopted. In this paper, a novel dual-source intra-guided material decomposition framework is proposed to suppress CB artifacts in the material maps. Firstly, a dual-source two-pass algorithm is developed for artifact pre-correction during image reconstruction. Then, the structure of small cone-angle regions from one X-ray source is utilized to guide cone beam artifact removal in large cone-angle regions from another source. Finally, direct matrix inverse material decomposition is applied to the filtered image. Extensive experiments have been conducted on the authentic human phantom and demonstrate that the proposed framework achieves excellent performance in cone beam artifact reduction compared to other methods, and significantly enhances the quality of the material maps.

关键词： Geometry Head Costs Imaging Phantoms Filtering algorithms Matrix decomposition Engineering in medicine and biology image reconstruction X-ray imaging

Full-Length-Body CBCT Imaging in Upright Position with Robotic-arm System: A Simulation Study

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Full-Length-Body CBCT Imaging in Upright Position with Robot...

IEEE International Symposium on Biomedical Imaging

作者： Tong Lin Tianling Lyu Zhan Wu Yan Xi Wentao Zhu Yang Chen Laboratory of Image Science and Technology Southeast University Nanjing China Research Center of Augmented Intelligence Zhejiang Lab Hangzhou China Shanghai First-Imaging Tech Shanghai China Jiangsu Provincial Joint International Research Laboratory of Medical Information Processing Southeast University Nanjing China Key Laboratory of New Generation Artificial Intelligence Technology and Its Interdisciplinary Applications Southeast University Nanjing China

ISBN: (数字)9798350313338

ISBN: (纸本)9798350313345

关键词： image quality Computed tomography Reconstruction algorithms Stability analysis Trajectory Safety Iterative methods

HU-Net: Hessian-incorporated U-Net for CBCT projection-domain metal segmentation with guidance from SAM

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HU-Net: Hessian-incorporated U-Net for CBCT projection-domai...

IEEE Conference on Cybernetics and Intelligent Systems

作者： Chen Jiang Tianling Lyu Gege Ma Yan Xi Yang Chen Wentao Zhu Zhejiang Lab Hangzhou China Hangzhou Institute for Advanced Study of UCAS Hangzhou China Shanghai First-Imaging Tech. Shanghai China Laboratory of Image Science and Technology Southeast University Nanjing China Jiangsu Provincial Joint International Research Laboratory of Medical Information Processing the Key Laboratory of New Generation Artificial Intelligence Technology and Its Interdisciplinary Applications Southeast University Nanjing China

ISBN: (数字)9798350364194

ISBN: (纸本)9798350364200

Metal artifact is a prevailing factor reducing the image quality of CBCT in minimally invasive spine surgery. In CBCT, conventional metal artifact reduction algorithms pay more attention to the inpainting of the metal traces, but metal segmentation is also challenging. Despite the current success in image segmentation with deep learning, the substantial expense associated with annotating metal traces in the projection domain makes most of these approaches impractical for this task. To address this, we propose a Hessian-incorporated U-Net (HU-Net) for CBCT projection-domain metal segmentation with guidance from SAM. The proposed method has been tested on both digital phantom data and clinical CBCT data. According to the experimental results, our method has demonstrated notable improvement in the segmentation of metal traces across both datasets. This paper presents a feasible approach for metal trace segmentation in the projection domain with deep learning and has the potential to be applied in clinical applications.

关键词： Deep learning image quality image segmentation Minimally invasive surgery Mechatronics Metals Phantoms

Denoising of 3D magnetic resonance images using a residual encoder-decoder wasserstein generative adversarial network

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arXiv 2018年

作者： Ran, Maosong Hu, Jinrong Chen, Yang Chen, Hu Sun, Huaiqiang Zhou, Jiliu Zhang, Yi College of Computer Science Sichuan University Chengdu610065 China Department of Computer Science Chengdu University of Information Technology Chengdu610225 China Lab of Image Science and Technology School of Computer Science and Engineering Southeast University Nanjing210096 China School of Cyber Science and Engineering Southeast University Nanjing210096 China Ministry of Education Nanjing210096 China Department of Radiology West China Hospital of Sichuan University Chengdu610041 China Guangdong Provincial Key Laboratory of Medical Image Processing Southern Medical University Guangzhou510515 China

Structure-preserved denoising of 3D magnetic resonance imaging (MRI) images is a critical step in medical image analysis. Over the past few years, many algorithms with impressive performances have been proposed. In this paper, inspired by the idea of deep learning, we introduce an MRI denoising method based on the residual encoder-decoder Wasserstein generative adversarial network (RED-WGAN). Specifically, to explore the structure similarity between neighboring slices, a 3D configuration is utilized as the basic processing unit. Residual autoencoders combined with deconvolution operations are introduced into the generator network. Furthermore, to alleviate the oversmoothing shortcoming of the traditional mean squared error (MSE) loss function, the perceptual similarity, which is implemented by calculating the distances in the feature space extracted by a pretrained VGG-19 network, is incorporated with the MSE and adversarial losses to form the new loss function. Extensive experiments are implemented to assess the performance of the proposed method. The experimental results show that the proposed RED-WGAN achieves performance superior to several state-of-the-art methods in both simulated and real clinical data. In particular, our method demonstrates powerful abilities in both noise suppression and structure preservation. Copyright © 2018, The Authors. All rights reserved.

关键词： Magnetic resonance imaging