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arXiv 2022年

作者： Maier-Hein, Lena Reinke, Annika Godau, Patrick Tizabi, Minu D. Buettner, Florian Christodoulou, Evangelia Glocker, Ben Isensee, Fabian Kleesiek, Jens Kozubek, Michal Reyes, Mauricio Riegler, Michael A. Wiesenfarth, Manuel Emre Kavur, A. Sudre, Carole H. Baumgartner, Michael Eisenmann, Matthias Heckmann-Nötzel, Doreen Rädsch, Tim Acion, Laura Antonelli, Michela Arbel, Tal Bakas, Spyridon Benis, Arriel Blaschko, Matthew B. Jorge Cardoso, M. Cheplygina, Veronika Cimini, Beth A. Collins, Gary S. Farahani, Keyvan Ferrer, Luciana Galdran, Adrian Ginneken, Bram Van Haase, Robert Hashimoto, Daniel A. Hoffman, Michael M. Huisman, Merel Jannin, Pierre Kahn, Charles E. Kainmueller, Dagmar Kainz, Bernhard Karargyris, Alexandros Karthikesalingam, Alan Kenngott, Hannes Kofler, Florian Kopp-Schneider, Annette Kreshuk, Anna Kurc, Tahsin Landman, Bennett A. Litjens, Geert Madani, Amin Maier-Hein, Klaus Martel, Anne L. Mattson, Peter Meijering, Erik Menze, Bjoern Moons, Karel G.M. Müller, Henning Nichyporuk, Brennan Nickel, Felix Petersen, Jens Rajpoot, Nasir Rieke, Nicola Saez-Rodriguez, Julio Sánchez, Clara I. Shetty, Shravya Smeden, Maarten Van Summers, Ronald M. Taha, Abdel A. Tiulpin, Aleksei Tsaftaris, Sotirios A. Calster, Ben Van Varoquaux, Gaël Jäger, Paul F. Heidelberg Division of Intelligent Medical Systems and HI Helmholtz Imaging Germany Faculty of Mathematics and Computer Science and Medical Faculty Heidelberg University Heidelberg Germany NCT Heidelberg a partnership between DKFZ University Medical Center Heidelberg Germany Faculty of Mathematics and Computer Science Heidelberg University Heidelberg Germany Heidelberg Division of Intelligent Medical Systems Germany partner site Frankfurt/Mainz a partnership between DKFZ and UCT Frankfurt-Marburg Germany Heidelberg Goethe University Frankfurt Germany Department of Medicine Goethe University Frankfurt Germany Department of Informatics Frankfurt Cancer Insititute Germany Department of Computing Imperial College London London United Kingdom Heidelberg Division of Medical Image Computing and HI Applied Computer Vision Lab Germany Institute for AI in Medicine University Medicine Essen Essen Germany Centre for Biomedical Image Analysis Faculty of Informatics Masaryk University Brno Czech Republic ARTORG Center for Biomedical Engineering Research University of Bern Bern Switzerland Department of Radiation Oncology University Hospital Bern University of Bern Bern Switzerland Simula Metropolitan Center for Digital Engineering Oslo Norway UiT The Arctic University of Norway Romsø Norway Heidelberg Division of Biostatistics Germany Heidelberg Division of Intelligent Medical Systems Division of Medical Image Computing HI Applied Computer Vision Lab Germany MRC Unit for Lifelong Health and Ageing UCL Centre for Medical Image Computing Department of Computer Science University College London London United Kingdom School of Biomedical Engineering and Imaging Science King’s College London London United Kingdom Heidelberg Division of Medical Image Computing Germany Instituto de Cálculo CONICET – Universidad de Buenos Aires Buenos Aires Argentina Centre for Medical Image Computing University College London London United Kingdom McGill University Montréal

Increasing evidence shows that flaws in machine learning (ML) algorithm validation are an underestimated global problem. Particularly in automatic biomedical image analysis, chosen performance metrics often do not reflect the domain interest, thus failing to adequately measure scientific progress and hindering translation of ML techniques into practice. To overcome this, we created Metrics Reloaded, a comprehensive framework guiding researchers in the problem-aware selection of metrics. It was developed by a large international consortium in a multi-stage Delphi process and is based on the novel concept of a problem fingerprint – a structured representation of the given problem that captures all aspects that are relevant for metric selection, from the domain interest to the properties of the target structure(s), data set and algorithm output. Based on the problem fingerprint, users are guided through the process of choosing and applying appropriate validation metrics while being made aware of potential pitfalls. Metrics Reloaded targets image analysis problems that can be interpreted as a classification task at image, object or pixel level, namely image-level classification, object detection, semantic segmentation, and instance segmentation tasks. To improve the user experience, we implemented the framework in the Metrics Reloaded online tool. Following the convergence of ML methodology across application domains, Metrics Reloaded fosters the convergence of validation methodology. Its applicability is demonstrated for various biomedical use cases. © 2022, CC BY.

关键词： Semantic Segmentation

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Benchmarking quality-dependent and cost-sensitive score-level multimodal biometric fusion algorithms

arXiv

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arXiv 2021年

作者： Poh, Norman Bourlai, Thirimachos Kittler, Josef Allano, Lorene Alonso-Fernandez, Fernando Ambekar, Onkar Baker, John Dorizzi, Bernadette Fatukasi, Omolara Fierrez, Julian Ganster, Harald Ortega-Garcia, Javier Maurer, Donald Salah, Albert Ali Scheidat, Tobias Vielhauer, Claus Centre for Vision Speech and Signal Processing School of Electronics and Physical Sciences University of Surrey Guildford SurreyGU2 7XH United Kingdom Biometrics Center Lane Department of Computer Science and Electrical Engineering College of Engineering and Mineral Resources West Virginia University MorgantownWV26506-6109 United States Institut Telecom Telecom and Management SudParis Evry91011 France Biometric Recognition Group – ATVS Escuela Politecnica Superior Universidad Autonoma de Madrid Madrid28049 Spain Amsterdam1098 XG Netherlands Applied Physics Laboratory Johns Hopkins University LaurelMD20723 United States Electronics and Physics Department Institut Telecom Telecom and Management SudParis Evry91011 France Institute of Digital Image Processing Joanneum Research Graz8010 Austria ISLA-ISIS University of Amsterdam Amsterdam1098 XG Netherlands Department of Informatics and Media Brandenburg University of Applied Sciences Brandenburg an der HavelD-14770 Germany Research Group Multimedia and Security Department of Technical and Business Information Systems Faculty of Computer Science Otto-von-Guericke-University of Magdeburg MagdeburgD-39106 Germany

Automatically verifying the identity of a person by means of biometrics (e.g., face and fingerprint) is an important application in our day-to-day activities such as accessing banking services and security control in airports. To increase the system reliability, several biometric devices are often used. Such a combined system is known as a multimodal biometric system. This paper reports a benchmarking study carried out within the framework of the BioSecure DS2 (Access Control) evaluation campaign organized by the University of Surrey, involving face, fingerprint, and iris biometrics for person authentication, targeting the application of physical access control in a medium-size establishment with some 500 persons. While multimodal biometrics is a well-investigated subject in the literature, there exists no benchmark for a fusion algorithm comparison. Working towards this goal, we designed two sets of experiments: quality-dependent and cost-sensitive evaluation. The quality-dependent evaluation aims at assessing how well fusion algorithms can perform under changing quality of raw biometric images principally due to change of devices. The cost-sensitive evaluation, on the other hand, investigates how well a fusion algorithm can perform given restricted computation and in the presence of software and hardware failures, resulting in errors such as failure-to-acquire and failure-to-match. Since multiple capturing devices are available, a fusion algorithm should be able to handle this nonideal but nevertheless realistic scenario. In both evaluations, each fusion algorithm is provided with scores from each biometric comparison subsystem as well as the quality measures of both the template and the query data. The response to the call of the evaluation campaign proved very encouraging, with the submission of 22 fusion systems. To the best of our knowledge, this campaign is the first attempt to benchmark quality-based multimodal fusion algorithms. In the presence of changing

关键词： Benchmarking

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Different ways of research on pricing done math model base on big data

Different ways of research on pricing done math model base o...

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International Conference on Mechatronics and Intelligent Robotics, ICMIR 2018

作者： Yang, Chenghui Peng, Xing Luo, Zhongfu Liu, Zeyi College of Electrical Engineering Northwest Minzu University No. 1 Northwest Xincun LanzhouGansu730030 China China National Institute of Information Research No. 1 Northwest Xincun LanzhouGansu730030 China School of Automation and Electrical Engineering Lanzhou Jiaotong University No. 188 AnNing West Rode LanzhouGansu730070 China Gansu Provincial Engineering Research Center for Artificial Intelligence and Graphics and Image Processing No. 188 AnNing West Rode LanzhouGansu730070 China School of Civil Engineering Northwest Minzu University No. 1 Northwest Xincun LanzhouGansu730030 China

ISBN: (纸本)9783030002138

The use of MATLAB, EXCEL and other software for the classification of data presentment, the completion of the task, through the comparison between the region and the price to find out the reasons for the task is not completed. Combined with the workflow scheduling framework, we take the solution of releasing crowdsourced packages to APP members by combining the tasks together, and combining with the operation flow of crowdsourcing mode, and using the reverse-oriented pricing method to get a new pricing method. Determine the optimal solution, come to the unfinished task area new pricing, improve the completion of the task rate, solve the "photo shoot money" APP task pricing problem. © Springer Nature Switzerland AG 2019.

关键词： MATLAB

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image-based material characterization of complex microarchitectured additively manufactured structures

arXiv

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arXiv 2019年

作者： Korshunova, N. Jomo, J. Lékó, G. Reznik, D. Balázs, P. Kollmannsberger, S. Chair for Computation in Engineering Technische Universität München Arcisstr. 21 München80333 Germany Research and Technology Center Siemens AG Corporate Technology Siemensdamm 50 Berlin13629 Germany Department of Image Processing and Computer Graphics University of Szeged Árpád tér 2 SzegedH-6720 Hungary

Significant developments in the field of additive manufacturing (AM) allowed the fabrication of complex microarchitectured components with varying porosity across different scales. However, due to the high complexity of this process, the final parts can exhibit significant variations in the nominal geometry. computer tomographic images of 3D printed components provide extensive information about these microstructural variations, such as process-induced porosity, surface roughness, and other undesired morphological discrepancies. Yet, techniques to incorporate these imperfect AM geometries into the numerical material characterization analysis are computationally demanding. In this contribution, an efficient image-to-material-characterization framework using the high-order parallel Finite Cell Method is proposed. In this way, a flexible non-geometry-conforming discretization facilitates mesh generation for very complex microstructures at hand and allows a direct analysis of the images stemming from CT-scans. Numerical examples including a comparison to the experiments illustrate the potential of the proposed framework in the field of additive manufacturing product simulation. Copyright © 2019, The Authors. All rights reserved.

关键词： 3D printers

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GazeGAN: A robust generative adversarial saliency model based on invariance analysis of human gaze during scene free viewing

arXiv

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arXiv 2019年

作者： Che, Zhaohui Borji, Ali Zhai, Guangtao Min, Xiongkuo Guo, Guodong Le Callet, Patrick Institute of Image Communication and Network Engineering Shanghai Key Laboratory of Digital Media Processing and Transmissions Shanghai Jiao Tong University Shanghai200240 China MarkableAI United States Institute of Deep Learning Baidu Research Department of Computer Science and Electrical Engineering West Virginia University MorgantownWV United States Equipe Image Perception et Interaction Laboratoire des Sciences du Numérique de Nantes Université de Nantes France

—Data size is the bottleneck for developing deep saliency models, because collecting eye-movement data is very time-consuming and expensive. Most of current studies on human attention and saliency modeling have used high-quality stereotype stimuli. In real world, however, captured images undergo various types of transformations. Can we use these transformations to augment existing saliency datasets? Here, we first create a novel saliency dataset including fixations of 10 observers over 1900 images degraded by 19 types of transformations. Second, by analyzing eye movements, we find that observers look at different locations over transformed versus original images. Third, we utilize the new data over transformed images, called data augmentation transformation (DAT), to train deep saliency models. We find that label-preserving DATs with negligible impact on human gaze boost saliency prediction, whereas some other DATs that severely impact human gaze degrade the performance. These label-preserving valid augmentation transformations provide a solution to enlarge existing saliency datasets. Finally, we introduce a novel saliency model based on generative adversarial network (dubbed GazeGAN). A modified U-Net is proposed as the generator of the GazeGAN, which combines classic "skip connections" with a novel "center-surround connection (CSC)", in order to leverage multi-level features. We also propose a histogram loss based on Alternative Chi-Square Distance (ACS HistLoss) to refine the saliency map in terms of luminance distribution. Extensive experiments and comparisons over 3 datasets indicate that GazeGAN achieves the best performance in terms of popular saliency evaluation metrics, and is more robust to various perturbations. We also provide a comprehensive quantitative comparison of 22 state-of-the-art saliency models on distorted images, which contributes a robustness benchmark for saliency community. Our code and data are available at: https://***/CZHQuality/

关键词： Luminance

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Universal enzymatic numerical P systems with small number of enzymatic variables

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Science China(Information Sciences) 2018年第9期61卷 38-49页

作者： Zhiqiang ZHANG Tingfang WU ANDrei P■UN Linqiang PAN Key Laboratory of Image Information Processing and Intelligent Control of Education Ministry of China School of Automation Huazhong University of Science and Technology Department of Computer Science Faculty of Mathematics and Computer ScienceUniversity of Bucharest Bioinformatics Department National Institute of Research and Development for Biological Sciences School of Electric and Information Engineering Zhengzhou University of Light Industry

Numerical P systems(for short, NP systems) are distributed and parallel computing models inspired from the structure of living cells and economics. Enzymatic numerical P systems(for short, ENP systems) are a variant of NP systems, which have been successfully applied in designing and implementing controllers for mobile robots. Since ENP systems were proved to be Turing universal, there has been much work to simplify the universal systems, where the complexity parameters considered are the number of membranes, the degrees of polynomial production functions or the number of variables used in the *** the number of enzymatic variables, which is essential for ENP systems to reach universality, has not been investigated. Here we consider the problem of searching for the smallest number of enzymatic variables needed for universal ENP systems. We prove that for ENP systems as number acceptors working in the all-parallel or one-parallel mode, one enzymatic variable is sufficient to reach universality; while for the one-parallel ENP systems as number generators, two enzymatic variables are sufficient to reach *** results improve the best known results that the numbers of enzymatic variables are 13 and 52 for the all-parallel and one-parallel systems, respectively.

关键词： bio-inspired computing numerical P system mobile robot membrane controller universality

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An improved convex programming model for the inverse problem in intensity-modulated radiation therapy

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International Journal of Performability Engineering 2018年第5期14卷 871-884页

作者： Lan, Yihua Zhang, Xingang Zhang, Jianyang Wang, Yang Hung, Chih-Cheng School of Computer and Information Technology Nanyang Normal University Nanyang473061 China Institute of Image Processing and Pattern Recognition Nanyang Normal University Nanyang473061 China Radiology Department Central Hospital of Nanyang Nanyang473061 China Laboratory for Machine Vision and Security Research College of Computing and Software Engineering Kennesaw State University - Marietta Campus 1100 South Marietta Parkway MariettaGA30067-2896 United States

Intensity modulated radiation therapy technology (IMRT) is one of the main approaches in cancer treatment because it can guarantee the killing of cancer cells while optimally protecting normal tissue from complications. Inverse planning, which is the core component of the entire IMRT system, is mainly based on accurate mathematical modeling and associated fast solving methods. In inverse planning, the fluence map optimization, which considers the multi-leaf collimator (MLC) modulation, is the current research focus. Although the hitting constrain problem with the unidirectional movement of leaf-sweeping has been solved, our goal is to solve the hitting constrain problem with the bidirectional movement of leaf-sweeping. In this study, we propose a non-synchronized type to solve the hitting constrain problem with the bidirectional movement of leaf-sweeping schemes for IMRT. In solving this problem, a new mathematical model is proposed under the framework of convex programming. The advantage of the convex model is to avoid the uncertainty and inaccuracy that occurs in the non-convex programming solving process. Experimental results for two clinical testing cases show that under the same condition of total number of monitoring units, the new proposed model produces better dose distribution than those of the total variance and quadratic models. © 2018 Totem Publisher, Inc. All rights reserved.

关键词： Convex optimization

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Common Limitations of image processing Metrics: A Picture Story

arXiv

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arXiv 2021年

作者： Reinke, Annika Tizabi, Minu D. Sudre, Carole H. Eisenmann, Matthias Rädsch, Tim Baumgartner, Michael Acion, Laura Antonelli, Michela Arbel, Tal Bakas, Spyridon Bankhead, Peter Benis, Arriel Blaschko, Matthew Buettner, Florian Cardoso, M. Jorge Chen, Jianxu Cheplygina, Veronika Christodoulou, Evangelia Cimini, Beth A. Collins, Gary S. Engelhardt, Sandy Farahani, Keyvan Ferrer, Luciana Galdran, Adrian van Ginneken, Bram Glocker, Ben Godau, Patrick Haase, Robert Hamprecht, Fred Hashimoto, Daniel A. Heckmann-Nötzel, Doreen Hirsch, Peter Hoffman, Michael M. Huisman, Merel Isensee, Fabian Jannin, Pierre Kahn, Charles E. Kainmueller, Dagmar Kainz, Bernhard Karargyris, Alexandros Karthikesalingam, Alan Kavur, A. Emre Kenngott, Hannes Kleesiek, Jens Kleppe, Andreas Koehler, Sven Kofler, Florian Kopp-Schneider, Annette Kooi, Thijs Kozubek, Michal Kreshuk, Anna Kurc, Tahsin Landman, Bennett A. Litjens, Geert Madani, Amin Maier-Hein, Klaus Martel, Anne L. Mattson, Peter Meijering, Erik Menze, Bjoern Moher, David Moons, Karel G.M. Müller, Henning Nichyporuk, Brennan Nickel, Felix Noyan, M. Alican Petersen, Jens Polat, Gorkem Rafelski, Susanne M. Rajpoot, Nasir Reyes, Mauricio Rieke, Nicola Riegler, Michael A. Rivaz, Hassan Saez-Rodriguez, Julio Sánchez, Clara I. Schroeter, Julien Saha, Anindo Selver, M. Alper Sharan, Lalith Shetty, Shravya Smeden, Maarten V.A.N. Stieltjes, Bram Summers, Ronald M. Taha, Abdel A. Tiulpin, Aleksei Tsaftaris, Sotirios A. Calster, Ben V.A.N. Varoquaux, Gaël Wiesenfarth, Manuel Yaniv, Ziv R. Jäger, Paul Maier-Hein, Lena Division of Intelligent Medical Systems and HI Helmholtz Imaging Heidelberg Germany Faculty of Mathematics and Computer Science Heidelberg University Heidelberg Germany Division of Intelligent Medical Systems Heidelberg Germany NCT Heidelberg DKFZ University Medical Center Heidelberg Germany MRC Unit for Lifelong Health and Ageing UCL Centre for Medical Image Computing Department of Computer Science University College London London United Kingdom School of Biomedical Engineering and Imaging Science King’s College London London United Kingdom Division of Medical Image Computing Heidelberg Germany Instituto de Cálculo CONICET – Universidad de Buenos Aires Buenos Aires Argentina Centre for Medical Image Computing University College London London United Kingdom McGill University Montréal Canada Division of Computational Pathology Dept of Pathology & Laboratory Medicine Indiana University School of Medicine IU Health Information and Translational Sciences Building Indianapolis United States University of Pennsylvania Richards Medical Research Laboratories FL7 PhiladelphiaPA United States Institute of Genetics and Cancer University of Edinburgh Edinburgh United Kingdom Department of Digital Medical Technologies Holon Institute of Technology Holon Israel European Federation for Medical Informatics Le Mont-sur-Lausanne Switzerland Center for Processing Speech and Images Department of Electrical Engineering KU Leuven Kasteelpark Arenberg 10 - box 2441 Leuven3001 Belgium Frankfurt/Mainz DKFZ UCT Frankfurt-Marburg Germany Heidelberg Germany Goethe University Frankfurt Department of Medicine Germany Goethe University Frankfurt Department of Informatics Germany Frankfurt Cancer Insititute Germany Leibniz-Institut für Analytische Wissenschaften – ISAS – e.V. Dortmund Germany Department of Computer Science IT University of Copenhagen Copenhagen Denmark Imaging Platform Broad Institute of MIT and Harvard CambridgeMA United States Centre for St

While the importance of automatic image analysis is continuously increasing, recent meta-research revealed major flaws with respect to algorithm validation. Performance metrics are particularly key for meaningful, objective, and transparent performance assessment and validation of the used automatic algorithms, but relatively little attention has been given to the practical pitfalls when using specific metrics for a given image analysis task. These are typically related to (1) the disregard of inherent metric properties, such as the behaviour in the presence of class imbalance or small target structures, (2) the disregard of inherent data set properties, such as the non-independence of the test cases, and (3) the disregard of the actual biomedical domain interest that the metrics should reflect. This living dynamically document has the purpose to illustrate important limitations of performance metrics commonly applied in the field of image analysis. In this context, it focuses on biomedical image analysis problems that can be phrased as image-level classification, semantic segmentation, instance segmentation, or object detection task. The current version is based on a Delphi process on metrics conducted by an international consortium of image analysis experts from more than 60 institutions worldwide. © 2021, CC BY.

关键词： Medical imaging

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Weakly supervised scene parsing with point-based distance metric learning

arXiv

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arXiv 2018年

作者： Qian, Rui Wei, Yunchao Shi, Honghui Li, Jiachen Liu, Jiaying Huang, Thomas Institute of Computer Science and Technology Peking University Beijing China IBM T.J. Watson Research Center Image Formation and Processing Group Beckman Institute UIUC

Semantic scene parsing is suffering from the fact that pixellevel annotations are hard to be collected. To tackle this issue, we propose a Point-based Distance Metric Learning (PDML) in this paper. PDML does not require dense annotated masks and only leverages several labeled points that are much easier to obtain to guide the training process. Concretely, we leverage semantic relationship among the annotated points by encouraging the feature representations of the intra- and intercategory points to keep consistent, i.e. points within the same category should have more similar feature representations compared to those from different categories. We formulate such a characteristic into a simple distance metric loss, which collaborates with the point-wise cross-entropy loss to optimize the deep neural networks. Furthermore, to fully exploit the limited annotations, distance metric learning is conducted across different training images instead of simply adopting an image-dependent manner. We conduct extensive experiments on two challenging scene parsing benchmarks of PASCALContext and ADE 20K to validate the effectiveness of our PDML, and competitive mIoU scores are achieved. Copyright © 2018, The Authors. All rights reserved.

关键词： Deep neural networks

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[P276] Impact on proton range estimates using a novel mr-based artifact reduction algorithm

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Physica Medica 2018年 52卷 179-180页

作者： Jonathan Scharff Nielsen Koen Van Leemput Jens M. Edmund Radiotherapy Research Unit Herlev and Gentofte Hospital Image Analysis and Computer Graphics Section Dtu Compute Department of Oncology Herlev Denmark Dtu-Technical University of Denmark Copenhagen Massachusetts General Hospital Harvard Medical School Image Analysis and Computer Graphics Section Lyngby Denmark Radiotherapy Research Unit Herlev and Gentofte Hospital University Hospital of Copenhagen The Niels Bohr Institute Copenhagen University Denmark Department of Oncology Herlev Denmark

Purpose Metal implants lead to streak and cupping artifacts in computed tomography (CT) images, causing erroneous CT number estimates for radiation therapy (RT) planning. We recently introduced kerMAR, a novel Magnetic Resonance (MR)-based CT metal artifact reduction algorithm that combines kernel regression on uncorrupted CT value/MR patch pairs with a forward model of the CT metal artifacts. Here, we compare the impact of kerMAR and the clinical oMAR algorithm (Philips) on the proton range in calculated spot scanning (SS) dose plans for proton RT. Methods We acquired T1w MR and CT image sets of a veal shank phantom with and without metal markers inserted, and applied kerMAR and oMAR to the former. We then created SS plans in Eclipse v. 13.7 (Varian) delivering 150 MeV protons in a 0.55 cm single spot that passed 1) near a metal marker at shallow depth and 2) near two different markers located at shallow (near bone) and deep depths, respectively. Similar images were acquired for 4 head-and-neck (HN) RT patients with dental implants , and plans using the same phantom beam, angled through the artifact corrupted oral cavity , were devised, leading to a configuration most resembling phantom beam 2. We finally recalculated the dose plans for the same beamline settings and monitor units on all CT sets, and compared the proton ranges defined as the depth with 80% of the maximum dose. Results For the phantom plans, the following range deviations relative to the metal-free reference plan (uncorrected CT, oMAR, kerMAR) were observed: Plan 1: (0.6, 0.6, 0.6)%; plan 2: (−4, −1.8, −2.1)%. The patient plans showed the following deviations from the uncorrected CT plan: kerMAR: (10, 8, −7, 11)%; oMAR: (3, 0.1, −10, 0.2)%. Conclusions Proton range calculations on a phantom showed similar improvements compared to the uncorrupted reference with kerMAR and oMAR. Similar calculations on HN patients, however, displayed systematic proton range increases when applying kerMAR as compared t

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