检索结果-内蒙古大学图书馆

Rapamycin promotes Schwann cell migration and nerve growth factor secretion

Neural Regeneration Research 2014年第6期9卷 602-609页

作者： Fang Liu Haiwei Zhang Kaiming Zhang Xinyu Wang Shipu Li Yixia Yin Department of Orthopedics Second Hospital of Yueyang State Key Laboratory of Advanced Technology for Materials Synthesis and Processing and Biomedical Materials and Engineering Center Wuhan University of Technology

Rapamycin, similar to FKS06, can promote neural regeneration in vitro. We assumed that the mechanisms of action of rapamycin and FK506 in promoting peripheral nerve regeneration were similar. This study compared the effects of different concentrations of raparnycin and FK506 on Sc hwann cells and investigated effects and mechanisms of rapamycin on improving peripheral nerve regeneration. Results demonstrated that the lowest rapamycin concentration （1.53 nmol/L） more significantly promoted Schwann cell migration than the highest FK506 concentration （100μmol/L）. Rapamycin promoted the secretion of nerve growth factors and upregulated growth-associated protein 43 expression in Schwann cells, but did not significantly affect Schwann cell proliferation. Therefore, rapamycin has potential application in peripheral nerve regeneration therapy.

关键词： nerve regeneration peripheral nerve injury rapamycin FK506 Schwann cell cell mi-gration nerve growth factor growth-associated protein 43 NSFC grant neural regeneration

来源：评论

学校读者我要写书评

暂无评论

Dynamic biointerfaces: from recognition to function

引用

Small (Weinheim an der Bergstrasse, Germany) 2015年第9-10期11卷 1097-112页

作者： Baisong Chang Mingxi Zhang Guangyan Qing Taolei Sun State Key Laboratory of Advanced Technology for Materials Synthesis and Processing Wuhan University of Technology Wuhan 430070 PR China.

The transformation of recognition signals into regulating macroscopic behaviors of biological entities (e.g., biomolecules and cells) is an extraordinarily challenging task in engineering interfacial properties of artificial materials. Recently, there has been extensive research for dynamic biointerfaces driven by biomimetic techniques. Weak interactions and chirality are two crucial routes that nature uses to achieve its functions, including protein folding, the DNA double helix, phospholipid membranes, photosystems, and shell and tooth growths. Learning from nature inspires us to design dynamic biointerfaces, which usually take advantage of highly selective weak interactions (e.g., synergetic chiral H-bonding interactions) to tailor their molecular assemblies on external stimuli. Biomolecules can induce the conformational transitions of dynamic biointerfaces, then drive a switching of surface characteristics (topographic structure, wettability, etc.), and eventually achieve macroscopic functions. The emerging progresses of dynamic biointerfaces are reviewed and its role from molecular recognitions to biological functions highlighted. Finally, a discussion is presented of the integration of dynamic biointerfaces with the basic biochemical processes, possibly solving the big challenges in life science.

关键词： H-bonding interactions biointerfaces biological functions chirality dynamic biointerfaces molecular recognition

来源：评论

学校读者我要写书评

暂无评论

Graphene-based composite photocatalytic materials for hydrogen production

Graphene-based composite photocatalytic materials for hydrog...

引用

2014国际纳米技术和新能源材料研讨会——暨世界著名科学家来鄂讲学计划武汉论坛

作者： Jiaguo Yu State Key Laboratory ofAdvanced Technology for Material Synthesis and Processing Wuhan University of Technology

The generation of chemical fuels by solar energy conversion is considered to be one of major strategies for solving the global energy and environmental problems in the future. Photocatalytic water splitting for H2 production has become an important and promising method for clean, economical, and renewal production of hydrogen by using solar light since Fujishima and Honda first r eported the photoelectrochemical water splitting on a TiO2 electrode in 1972. Among various semiconductors, titania (TiO2 ) has drawn special

关键词： Graphene-based composite photocatalytic materials for hydrogen production

来源：评论

学校读者我要写书评

暂无评论

Effect of sintering atmosphere on pore properties and microstructure of YAG porous ceramics

引用

Rengong Jingti Xuebao/Journal of Synthetic Crystals 2015年 44卷 221-224and233页

作者： Song, Jie-Guang Xu, Ming-Han Du, Da-Ming Wang, Fang Li, Shi-Bin Ma, Ming-Liang Ji, Gang-Chang Chen, Fei Engineering and Technology Research Center for Materials Surface Remanufacturing of Jiangxi Province School of Mechanical and Materials Engineering Jiujiang University Jiujiang China State Key Laboratory of Advanced Technology for Materials Synthesis and Processing Wuhan University of Technology Wuhan China

The YAG porous ceramics were prepared under different sintering atmosphere. The results show that the amount of sintering neck increases as holding time prolonging and sintering temperature increasing, which improves the binding degree among ceramic particles. YAG porous ceramics are sintered at 1550 for 2 h through considering the cost performance. The pore microstructure of prepared YAG porous ceramics via the vacuum sintering method is more homogeneous than that prepared via the atmosphere sintering method and the pore shape is more smooth. In addition, the binding degree of prepared YAG porous ceramics between the ceramic particles via the vacuum sintering method is higher than that prepared via the atmosphere sintering method. © 2015, Chinese Ceramic Society. All right reserved.

关键词： Yttrium aluminum garnet

来源：评论

学校读者我要写书评

暂无评论

Highly porous TiO 2 hollow microspheres constructed by radially oriented nanorods chains for high capacity, high rate and long cycle capability lithium battery

引用

Nano Energy 2015年 16卷 339-349页

作者： Jun Jin Shao-Zhuan Huang Jie Shu Hong-En Wang Yu Li Yong Yu Li-Hua Chen Bin-Jie Wang Bao-Lian Su Laboratory of Living Materials at the State Key Laboratory of Advanced Technology for Materials Synthesis and Processing Wuhan University of Technology 122 Luoshi Road 430070 Wuhan Hubei China Faculty of Materials Science and Chemical Engineering Ningbo University 818 Fenghua Road 315211 Ningbo Zhejiang China FEI Company Shanghai Nanoport 399 Shengxia Road 201210 Shanghai China Laboratory of Inorganic Materials Chemistry (CMI) University of Namur 61 rue de Bruxelles B-5000 Namur Belgium Department of Chemistry and Clare Hall College University of Cambridge UK

Hierarchical nanorods chains-constructed TiO 2 hollow microspheres (HNC-TiO 2 -HMSs) have been designed and prepared through a facile one-pot fluorine-free solvothermal alcoholysis route using TiCl 4 and isopropanol reaction system. Owing to the assembly of radially oriented nanorods chains leading to the formation of the shell of the hollow spheres, a large series of straight channels along nanorods chains are formed. Such highly porous hollow microspheres with hollow cavity, straight nanorods chains and straight nanochannels are highly desirable for Li ions batteries because such structure can easily store the electrolyte, facilitate the charge diffusion and Li + insertion and buffer the volume change during the Li + insertion/extraction process. One of the key innovation of the present work is the fine tuning of water amount released from the esterification of alcohol to induce in a well controlled hydrolysis of TiCl 4 and engineer precisely HNC-TiO 2 -HMSs formation. Most importantly, the released Cl − ions direct the nanorods growing along (001) crystal plane and self-assembling along the radial direction accompanying with nanorods size controlling to form HNC-TiO 2 -HMSs. The obtained TiO 2 anode material with such special structure demonstrates excellent Li + storage capacity with outstanding cycle performance and superior rate capability at different rates over 700 cycles: a reversible capacity of 216 mA h g −1 is obtained after 100 cycles at 1 C and a reversible capacity of 112 mA h g −1 is retained after 100 cycles at 10 C. The SEM, TEM, HRTEM and in-situ XRD techniques have been utilized to shed light on the Li + insertion process and the phase transformation. Most importantly, a self-improving phenomenon of cycle performance and storage capacity was observed owing to the formation of numerous ~5 nm Li 2 Ti 2 O 4 nanocrystals formed on the surface of the nanorods chains. The results reveal that the high performance of the as-prepared HNC

关键词： Highly porous hollow microspheres TiO 2 Nanorods chains Lithium ion batteries Self-improving phenomenon

来源：评论

学校读者我要写书评

暂无评论

Nanowire Thin Film Devices for Electrochemical Energy Storage

Nanowire Thin Film Devices for Electrochemical Energy Storag...

引用

第十四届全国固体薄膜学术会议

作者： Xiujuan Wei Mengyu Yan Lin Xu Yunlong Zhao Chunhua Han Liang He Liqiang Mai State Key Laboratory of Advanced Technology for Materials Synthesis and Processing.WUT-Harvard Joint State Key Laboratory of Advanced Technology for Materials Synthesis and Processing.WUT-Harvard Joint

Nanowires have attracted increasing interests because one-dimensional (1-D) nanomaterials can offer a range of unique advantages in many energy related fields.[1-6] For previous Iithium battery applications, bulk materials made of nanowires were usually used as the *** the electrochemical properties could be improved, the fast capacity fading is still one of the key issues and the intrinsic reasons are not clear until *** situ probing has been increasingly employed in nanotechnology.[7-8] To understand intrinsic reason of capacity fading,we designed the single nanowire electrochemical devices for in situ probing the direct relationship between electrical transport, structure, and electrochemical properties of the single nanowire electrode, which may push the fundamental limits of the nanowire materials for energy storage applications.[9] Our results show that conductivity of the nanowire electrode decreased during theelectrochemical reaction, which limits the cycle life of the devices.

关键词：

来源：评论

学校读者我要写书评

暂无评论

Effects of PRGD/PDLLA/β-TCP conduit on peripheral nerve regeneration and neuroma formation

Effects of PRGD/PDLLA/β-TCP conduit on peripheral nerve reg...

引用

第四届国际神经再生高峰论坛(INRS2014)暨第九届亚太神经再生论坛(APSNR2014)暨第六届脊髓损伤治疗与临床试验国际交流会(ISCITT2014)

作者： Yixia Yin Jiling Yi Tong Qiu Qiongjiao Yan Honglian Dai Shipu Li State Key Laboratory of Advanced Technology for Materials Synthesis and Processing Wuhan University of Technology

Peripheral nerve injury is the common cause that leads to disability. Large nerve defect and traumatic neuroma are two main bottleneck problems during repairing after peripheral nerve injury. So far, there is very limited research on neuroma inhibition with nerve conduit. Our group previously found that a PDLLA/PRGD/β-TCP composite conduit had beneficial effect on nerve regeneration, and no obvious neuroma formation was found in 00 experimental animals（Huang et al., 2013;Qiu et al., 2014）. Neuroma formation is based on excessively sedimentary collagen proliferation. We hypothesized that PDLLA/PRGD/β-TCP composite had the effect on the neural scar formation-related cytokines such as NGF, IFN-γ, etc., gene expression and protein level of collagen. In in vitro test, PRGD/PDLLA/β-TCP membranes showed better cytocompatibility with Schwann cells. In vivo tests demonstrated that PRGD/PDLLA/β-TCP conduits effectively promoted axonal regeneration of 10 mm rat sciatic nerve defect, which was close to the success of autograft. After an observation period of 1, 3, 6 month, PRGD/PDLLA/β-TCP conduit-implanted showed no neuroma and significantly improving on the neurophysiological and neuropathological levels compared with the PDLLA conduit as control group. The microenvironment of the inner conduit, containing an appropriate concentration of calcium ion, growth factors and immunologic factors（Figure 1）, played an important role in the inhibition of neuroma formation. The effect of the conduit on neural scar distributionand scar ratio, nerve function recovery, and structure of regenerated myelin sheath has been studied. The neural scar distribution is perineural scarring and the scar ratio is lower than the control of PDLLA group（Figure 2）. The study revealed that PRGD/PDLLA/β-TCP conduits promoted nerve regeneration and inhibited neuroma formation. It will provide experimental basis for future studies in nerve conduits for inhibition of neuroma formation and promoting long-distan

关键词： anerve repairing composite neural scar cytokine inhibition neuroma formation

来源：评论

学校读者我要写书评

暂无评论

Preparation of ATO thin films from SPS-derived large size ATO ceramic targets by PVD methods

Preparation of ATO thin films from SPS-derived large size AT...

引用

8th International Conference on processing and Manufacturing of advanced materials, THERMEC 2013

作者： Chen, Fei Wu, Jun Yan Shen, Qiang Schoenung, Julie M. Zhang, Lian Meng State Key Laboratory of Advanced Technology for Materials Synthesis and Processing Wuhan University of Technology Wuhan 430070 China Key Laboratory of Advanced Technology for Specially Functional Materials Ministry of Education Wuhan University of Technology Wuhan 430070 China Department of Chemical Engineering and Materials Science University of California Davis CA 95616 United States

ISBN: (纸本)9783038350736

Good crystalline of ATO thin films is necessary to improve the electrical and optical properties. In this paper, ATO thin films were fabricated using PLD method at high temperature of 550 °C, and the effect of laser energy density on the microstructure, electrical property and optical property of the ATO films is discussed. The results suggest that ATO films show good crystalline when deposited at high temperature of 550 °C. Both the electrical and optical properties have been enhanced with the increasing of laser energy density. When the laser energy density is 5.4 J/cm2, the lowest resistivity of ATO thin film is obtained with the value of 6.52×10-4 Ω·cm and the average optical transmittances is 82.0%. © (2014) Trans Tech Publications, Switzerland.

关键词： Pulsed laser deposition

来源：评论

学校读者我要写书评

暂无评论

synthesis and Characterization of Bismuth Nanowires via Seeded Growth Approach

Synthesis and Characterization of Bismuth Nanowires via Seed...

引用

2014国际纳米技术和新能源材料研讨会——暨世界著名科学家来鄂讲学计划武汉论坛

作者： Xin Mu Wenyu Zhao Danqi He Hongyu Zhou Wanting Zhu Qingjie Zhang State Key Laboratory of Advanced Technology for Materials Synthesis and Processing Wuhan University of Technology

Nanowires have attracted extensive attention in improving the thermoelectric figure of m erit ZT due to quantum confinement effect and enhanced phonon scattering. In this work, a seeded growth approach composed of seed synthesis and seed growth was first proposed to synthesize of bismuth nanowires. Bismuth seeds, as nucleation center of growing bismuth nanowires, were first synthesized by reducing BiCl3 in the ice

关键词： synthesis and Characterization of Bismuth Nanowires via Seeded Growth Approach

来源：评论

学校读者我要写书评

暂无评论

Design and synthesis of Artificial Photosynthesis Bioreactor for Carbon Dioxide Conversion

Design and Synthesis of Artificial Photosynthesis Bioreactor...

引用

2014第七届国际工业生物技术大会

作者： Xiao-Yu Yang Nan Jiang Wei Geng Guo-Liang Ting Shao-Yin Liu Bao-Lian Su State Key Laboratory of Advanced Technology for Materials Synthesis and Processing Wuhan University of Technology

It is of great importance to utilize solar energy and convert CO in the fields of energy,environment and sustainable *** photosynthetic bioreactor has been paid more attention due to its "green and natural" photosynthesis process,which can directly eliminate CO and convert CO to biomass by using ***,photosynthetic bioentities used in artificial photosynthesis bioreactor are often unstable,especially in adverse *** technology is an essential approach to improve the stability and reusability of photosynthetic bioentities for further applications in biosensors,biofuel cells,such as layer-by-layer and sol-gel ***,the stability and reusability of photosynthesis bioreactor have proven *** approach is to design a biocompatible biohybrid shell for the encapsulation and stabilization of single photosynthesis cell as the core of artificial photosynthesis *** material as the shell is advantageous for protecting photosynthetic bioentities from chemical and physical affection and beneficial for mass diffusion as well as endowing photosynthetic bioentities with exogenous properties such as anti-UV,heat-tolerance,acid-alkaline ***,this method can also be extended to diverse living organisms,which is essential for the potential applications in the development of energy exploitation,water treatment,and environment *** instance,in the technology for removal of organic sulfur from fossil fuels,the high stability of encapsulated desulphurizing bacteria could have greater desulfurizing activity and operational stability and may be potential for large-scale industrial ***,the strategy will also beneficial for the stability of artificial hydrogen bio-production *** believe that it will open up a new door to use a simple and green approach to fabricate stable artificial photosynthesis bioreactors for CO conversion,energy and environment m

关键词： Design and synthesis of Artificial Photosynthesis Bioreactor for Carbon Dioxide Conversion

来源：评论

学校读者我要写书评

暂无评论

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

请选择保存的检索档案：

请选择收藏分类：

通借通还

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：