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Electrically and thermally tunable multifunctional terahertz metasurface array

Physical Review A 2022年第3期105卷 033520-033520页

作者： Yue Wang Dajian Cui Yu Wang Guohui Yang Chunhui Wang National Key Laboratory of Tunable Laser Technology Harbin Institute of Technology Harbin Heilongjiang 150001 China Glint Institute of Artificial Intelligence and Robotics Shenzhen Guangdong 518063 China The 44th Research Institute of China Electronics Technology Group Corporation Chongqing 400060 China The School of Electronic and Information Engineering Harbin Institute of Technology Harbin Heilongjiang 150001 China

In this paper we propose a kind of all-solid-state and a hybrid electrically and thermally tunable multifunctional metasurface array based on the graphene pattern and vanadium dioxide configuration, which can realize the functions of band-stop filtering, beam steering, and beam splitting. When VO2 is in the dielectric state, this metasurface can be used as an angle-insensitive filter that can realize the function of the dual-frequency adjustable band-stop filtering by changing the Fermi level of graphene in the range of 4.11–6.51 THz. When VO2 is in the metal state, this metasurface can be used as a terahertz phased array device. By changing the Fermi level of graphene and the phase distribution, it is proved that this metasurface can achieve a specific deflection angle, a continuous scanning range of 0–68.37∘, or beam splitting at angles of ±25.56∘ and ±59.29∘. Our work shows great potential in the field of multifunctional integrated chips.

关键词： Metamaterials Photonics Plasmonics Split-ring resonators

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Natural product 1,2,3,4,6-penta-O-galloyl-β-D-glucopyranose is a reversible inhibitor of glyceraldehyde 3-phosphate dehydrogenase

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中国药理学报（英文版） 2022年第2期43卷 470-482页

作者： Wen Li Li-ping Liao Ning Song Yan-jun Liu Yi-luan Ding Yuan-yuan Zhang Xiao-ru Zhou Zhong-ya Sun Sen-hao Xiao Hong-bo Wang Jing Lu Nai-xia Zhang Hua-liang Jiang Kai-xian Chen Chuan-peng Liu Jie Zheng Ke-hao Zhao Cheng Luo School of Pharmacy Key Laboratory of Molecular Pharmacology and Drug Evaluation(Yantai University)Ministry of EducationCollaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of ShandongYantai UniversityYantai 264005China Drug Discovery and Design Center the Center for Chemical BiologyState Key Laboratory of Drug ResearchShanghai Institute of Materia MedicaChinese Academy of SciencesShanghai 201203China University of Chinese Academy of Sciences Beijing 100049China University of Chinese Academy of Sciences Beijing 100049China Center of Immunological Diseases Shanghai Institute of Materia MedicaChinese Academy of SciencesShanghai 201203China Drug Discovery and Design Center the Center for Chemical BiologyState Key Laboratory of Drug ResearchShanghai Institute of Materia MedicaChinese Academy of SciencesShanghai 201203China Department of Gastroenterology Xinhua HospitalSchool of MedicineShanghai Jiaotong UniversityShanghai 201210China Department of Analytical Chemistry Shanghai Institute of Materia MedicaChinese Academy of SciencesShanghai 201203China Drug Discovery and Design Center the Center for Chemical BiologyState Key Laboratory of Drug ResearchShanghai Institute of Materia MedicaChinese Academy of SciencesShanghai 201203China Drug Discovery and Design Center the Center for Chemical BiologyState Key Laboratory of Drug ResearchShanghai Institute of Materia MedicaChinese Academy of SciencesShanghai 201203China University of Chinese Academy of Sciences Beijing 100049China School of Life Science and Technology Shanghai Tech UniversityShanghai 201210China Drug Discovery and Design Center the Center for Chemical BiologyState Key Laboratory of Drug ResearchShanghai Institute of Materia MedicaChinese Academy of SciencesShanghai 201203China School of Life Science and Technology Harbin Institute of TechnologyHarbin 200092China Drug Discovery and Design Center the Center for Chemical BiologyState Key Laboratory of Drug ResearchSha

Aerobic glycolysis,also known as the Warburg effect,is a hallmark of cancer cell glucose metabolism and plays a crucial role in the activation of various types of immune *** 3-phosphate dehydrogenase(GAPDH)catalyzes the conversion of D-glyceraldehyde 3-phosphate to D-glycerate 1,3-bisphosphate in the 6th critical step in *** exerts metabolic flux control during aerobic glycolysis and therefore is an attractive therapeutic target for cancer and autoimmune ***,GAPDH inhibitors were reported to function through common suicide inactivation by covalent binding to the cysteine catalytic residue of ***,by developing a high-throughput enzymatic screening assay,we discovered that the natural product 1,2,3,4,6-penta-O-galloyl-β-D-glucopyranose(PGG)is an inhibitor of GAPDH with Ki=0.5 μ*** blocks GAPDH activity by a reversible and NAD+and Pi competitive mechanism,suggesting that it represents a novel class of GAPDH ***-depth hydrogen deuterium exchange mass spectrometry(HDX-MS)analysis revealed that PGG binds to a region that disrupts NAD+and inorganic phosphate binding,resulting in a distal conformational change at the GAPDH tetramer *** addition,structural modeling analysis indicated that PGG probably reversibly binds to the center pocket of ***,PGG inhibits LPS-stimulated macrophage activation by specific downregulation of GAPDH-dependent glucose consumption and lactate *** summary,PGG represents a novel class of GAPDH inhibitors that probably reversibly binds to the center pocket of *** study sheds new light on factors for designing a more potent and specific inhibitor of GAPDH for future therapeutic applications.

关键词： glyceraldehyde 3-phosphate dehydrogenase 1,2,3,4,6-penta-O-galloyl-β-D-glucopyranose hydrogen deuterium exchange mass spectrometry reversible inhibitor glycolysis

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How Collective Intelligence Emerges in a Crowd of People Through Learned Division of Labor: A Case Study

How Collective Intelligence Emerges in a Crowd of People Thr...

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IEEE International Conference on systems, Man and Cybernetics

作者： Dekun Wang Hongwei Zhang Guangdong Provincial Key Laboratory of Intelligent Morphing Mechanisms and Adaptive Robotics School of Mechanical Engineering and Automation Harbin Institute of Technology Shenzhen Guangdong P.R. China

ISBN: (数字)9781665410205

ISBN: (纸本)9781665410212

This paper investigates the factors fostering collective intelligence (CI) through a case study of *LinVi's Experiment, where over 2000 human players collectively controll an avatar car. By conducting theoretical analysis and replicating observed behaviors through numerical simulations, we demonstrate how self-organized division of labor (DOL) among individuals fosters the emergence of CI and identify two essential conditions fostering CI by formulating this problem into a stability problem of a Markov Jump Linear system (MJLS). These conditions, independent of external stimulus, emphasize the importance of both elite and common players in fostering CI. Additionally, we propose an index for emergence of CI and a distributed method for estimating joint actions, enabling individuals to learn their optimal social roles without global action information of the whole crowd.

关键词： Linear systems Avatars Stability criteria Collective intelligence Numerical simulation Resource management Indexes Automobiles Numerical stability Cybernetics

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End-to-end Semantic Segmentation Network for Low-Light Scenes

End-to-end Semantic Segmentation Network for Low-Light Scene...

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IEEE International Conference on robotics and Automation (ICRA)

作者： Hongmin Mu Gang Zhang MengChu Zhou Zhengcai Cao College of Information Science and Technology Beijing University of Chemical Technology Beijing China Department of Macao Institute of Systems Engineering Macau University of Science and Technology Macao China Helen and John C. Hartmann Department of Electrical and Computer Engineering New Jersey Institute of Technology Newark NJ USA State Key Laboratory of Robotics and Systems Harbin Institute of Technology Harbin China

ISBN: (数字)9798350384574

ISBN: (纸本)9798350384581

In the fields of robotic perception and computer vision, achieving accurate semantic segmentation of low-light or nighttime scenes is challenging. This is primarily due to the limited visibility of objects and the reduced texture and color contrasts among them. To address the issue of limited visibility, we propose a hierarchical gated convolution unit, which simultaneously expands the receptive field and restores edge texture. To address the issue of reduced texture among objects, we propose a dual closed-loop bipartite matching algorithm to establish a total loss function consisting of the unsupervised illumination enhancement loss and supervised intersection-over-union loss, thus enabling the joint minimization of both losses via the Hungarian algorithm. We thus achieve end-to-end training for a semantic segmentation network especially suitable for handling low-light scenes. Experimental results demonstrate that the proposed network surpasses existing methods on the Cityscapes dataset and notably outperforms state-of-the-art methods on both Dark Zurich and Nighttime Driving datasets.

关键词： Training Computer vision Accuracy Convolution Semantic segmentation Lighting Logic gates

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Experimental jet control with Bayesian optimization and persistent data topology

arXiv

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arXiv 2024年

作者： Reumschüssel, Johann Moritz Li, Yiqing Nedden, Philipp Maximilian zur Wang, Tianyu Noack, Bernd R. Paschereit, Christian Oliver Fluid Dynamics Technische Universität Berlin Germany Artificial Intelligence and Aerodynamics School of Mechanical Engineering and Automation Harbin Institute of Technology Shenzhen518055 China Guangdong Provincial Key Laboratory of Intelligent Morphing Mechanisms and Adaptive Robotics Harbin Institute of Technology Shenzhen518055 China

This study experimentally optimizes the mixing of a turbulent jet at Reynolds number 10000 with the surrounding air by targeted shear layer actuation. The forcing is composed of superposed harmonic signals of different azimuthal wavenumber m generated by eight loudspeakers circumferentially distributed around the nozzle lip. Amplitudes and frequencies of the individual harmonic contributions serve as optimization parameters and the time-averaged centerline velocity downstream of the potential core is used as a metric for mixing optimization. The actuation is optimized through Bayesian optimization. Three search spaces are explored — axisymmetric forcing, m = 0, superposed axisymmetric and helical forcing, m ∈ {0, 1}, and axisymmetric actuation combined with two counter-rotating helical modes, m ∈ {−1, 0, 1}. High-speed PIV is employed to analyze the jet response to the optimized forcing. The optimization processes are analyzed by persistent data topology. In the search space of axisymmetric excitation, the routine identifies an actuation at the natural frequency of the flow to be most efficient, with the centerline velocity being decreased by 15%. The optimal solutions in both the two-mode and three-mode search space converge to a similar forcing with one axial and one helical mode combined at a frequency ratio of around 2.3. Spectral analysis of the PIV images reveals that for the identified optimal forcing frequencies, a non-linear interaction between forced and natural structures in the jet flow is triggered, leading to a reduction in centerline velocity of around 35%. The topology of the most complex search space from the discrete data reveals four basins of attractions, classified into three forcing patterns including axisymmetric, axisymmetric-helical, and axisymmetric-flapping. Two deep basins are related to the optimal pattern found as axisymmetric-helical, and the others are shallower. © 2024, CC BY-NC-SA.

关键词： Topology

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Strenuous exercise-tolerance stretchable dry electrodes for continuous multi-channel electrophysiological monitoring

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npj Flexible Electronics 2022年第1期6卷 745-753页

作者： Ruijie Xie Qingsong Li Lijun Teng Zhengshuai Cao Fei Han Qiong Tian Jing Sun Yang Zhao Mei Yu Dianpeng Qi Peizhi Guo Guanglin Li Fengwei Huo Zhiyuan Liu CAS Key Laboratory of Human-Machine Intelligence-Synergy Systems Shenzhen Institutes of Advanced TechnologyChinese Academy of Sciences(CAS)Shenzhen 518055China The Institute of Flexible Electronics(IFE Future Technologies)Xiamen UniversityXiamen361005 FujianChina Key Laboratory of Flexible Electronics(KLOFE) School of Flexible Electronics(Future Technologies)Nanjing Tech University30 South Puzhu RoadNanjing 211816China Institute of Materials for Energy and Environment State Key Laboratory of Bio-fibers and Eco-textilesCollege of Materials Science and EngineeringQingdao UniversityQingdao 266071China MIIT Key Laboratory of Critical Materials Technology for New Energy Conversion and Storage School of Chemistry and Chemical EngineeringHarbin Institute of TechnologyHarbin 150001China

Electrophysiological monitoring under strenuous exercise by using stretchable dry electrodes is vital for healthcare monitoring,prosthetic control,human−machine interfaces and other biomedical ***,the existing dry electrodes are not applicable to the strenuous exercise situation that always involves both fast moving and profuse ***,we present a nano-thick porous stretchable dry electrode system with high stretchability and water *** system attaches conformably to the skin and stretches with it under Van der Waals forces even at sweating conditions,allowing the detection of electromyogram when moving with an acceleration of 10 g at a sweating rate of 2.8 mg cm^(−2) min^(−1).It is also capable of acquiring electrocardiogram and electroencephalogram *** strategy proposed would enable the biomedical studies and related applications with the requirement of stably recording electrophysiological signals under strenuous exercise scenarios.

关键词： acceleration recording enable

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Filter algorithm based on cochlear mechanics and neuron filter mechanism and application on enhancement of audio signals

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Journal of Central South University 2021年第6期28卷 1813-1828页

作者： GAO Wa KAN Yue ZHA Fu-sheng College of Furnishings and Industrial Design Nanjing Forestry UniversityNanjing 210037China School of Mechanical and Power Engineering Henan Polytechnic UniversityJiaozuo 454003China The State Key Laboratory of Robotics and System Harbin Institute of TechnologyHarbin 150001China

A filter algorithm based on cochlear mechanics and neuron filter mechanism is proposed from the view point of *** helps to solve the problem that the non-linear amplification is rarely considered in studying the auditory filters.A cochlear mechanical transduction model is built to illustrate the audio signals processing procedure in cochlea,and then the neuron filter mechanism is modeled to indirectly obtain the outputs with the cochlear properties of frequency tuning and non-linear *** mathematic description of the proposed algorithm is derived by the two *** parameter space,the parameter selection rules and the error correction of the proposed algorithm are *** unit impulse responses in the time domain and the frequency domain are simulated and compared to probe into the characteristics of the proposed *** a 24-channel filter bank is built based on the proposed algorithm and applied to the enhancements of the audio *** experiments and comparisons verify that,the proposed algorithm can effectively divide the audio signals into different frequencies,significantly enhance the high frequency parts,and provide positive impacts on the performance of speech enhancement in different noise environments,especially for the babble noise and the volvo noise.

关键词： cochlea neuron filter audio signal processing speech enhancement

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Data-based Stabilization of Unknown Discrete-time 2-D Roesser systems

Data-based Stabilization of Unknown Discrete-time 2-D Roesse...

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International Conference on Machine Learning and Cybernetics (ICMLC)

作者： Runmin Yang Rongni Yang Renjie Ma Yanzheng Zhu Peng Shi School of Control Science and Engineering Shandong University Jinan China State Key Laboratory of Robotics and Systems Harbin Institute of Technology Harbin China College of Electrical Engineering and Automation Shandong University of Science and Technology Qingdao China School of Electrical and Mechanical Engineering University of Adelaide Adelaide SA Australia

ISBN: (数字)9798331528041

ISBN: (纸本)9798331528058

This paper studies the stabilization problem of discrete-time two-dimensional (2-D) systems represented by Roesser based on available data. First of all, based on the pre-collected input-state data, the original system is transformed into a data-based form. Then a set is established to represent all systems capable of generating the given data, thereby indirectly stabilizing the original system by stabilizing all systems within this set. Next, by utilizing the S-procedure, sufficient conditions are established for the resultant closed-loop systems that incorporate a state feedback controller based on collected data. Finally, an example is given to demonstrate the effectiveness of the proposed approach.

关键词： Sufficient conditions state feedback Two-dimensional displays Transforms Machine learning Stability analysis Data models Numerical models Closed loop systems Numerical stability

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Research on Programmable Spatial Capture Mechanism and its Motion Characteristics Based on Origami Principle

SSRN

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SSRN 2022年

作者： Wang, Gang Wang, Jingtian Yao, Yimeng Yang, Fei Yue, Honghao Hebei Province Micro-nano Satellite Collaborative Innovation Center North China Institute Of Aerospace Engineering Langfang065000 China State Key Laboratory of Robotics and System Harbin Institute of Technology Harbin150001 China

In view of the capture requirements of non-cooperative targets in space debris removal tasks, this paper designs a programmable spatial capture mechanism by using the closed envelope characteristic of the origami mechanism. An enveloping origami mechanism was proposed and its programmable parametric design was carried out. Firstly, the kinematic model of the origami mechanism was established and the motion law of the axisymmetric folding state of the origami mechanism was analyzed. The folding performance of the origami mechanism under the three parameter characteristics of equal proportion crease length, equal proportion folding plate area and equal proportional configuration angle. The optimal parameters of the origami mechanism with closed edges, large envelope space, smooth envelope contour, small windup and smooth folding motion were obtained. The drive mechanism was designed for the motion characteristics of the axisymmetric folding origami mechanism. The simulation software was used to simulate the capture of space debris by origami mechanisms in a microgravity environment. The simulation results show that the origami mechanism can achieve the space debris capture task with highly reliable, large tolerance and enveloping. © 2022, The Authors. All rights reserved.

关键词： Space debris

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Underwater Robots and key Technologies for Operation Control

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Cyborg and Bionic systems 2024年第1期5卷 611-626页

作者： Linxiang Sun Yu Wang Xiaolong Hui Xibo Ma Xuejian Bai Min Tan School of Automation Harbin University of Science and TechnologyHarbinChina State Key Laboratory of Multimodal Artificial Intelligence Systems Institute of AutomationChinese Academy of SciencesBeijingChina School of Artificial Intelligence University of Chinese Academy of SciencesBeijing 100049China School of Electrical Engineering Liaoning University of TechnologyJinzhouChina Institute of Automation Chinese

Over time,the utilization of the Underwater Vehicle-Manipulator system(UVMS)has steadily increased in exploring and harnessing marine ***,the underwater environment poses big challenges for controlling,navigating,and communicating with *** challenges have not only spurred the continuous advancement of related technologies,but also made the development of the UVMS even more *** article firstly provides a review of development status of the UVMS and discusses the current limitations and future directions,and then reviews in detail the dynamic and hydrodynamic modeling methods,and analyzes the principles,advantages,and disadvantages of various ***,we try to review 2 key technologies of operation control methods,including underwater positioning and navigation technologies and vehicle-manipulator coordinated control ***,a reasonable prospect for the future development of UVMS is given.

关键词： operation control exploring harnessing marine resourceshoweverthe dynamic modeling vehicle manipulator coordinated control underwater robots navigation technologies UVMS hydrodynamic modeling

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