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Prediction of Intrinsically Disordered Proteins with a Low Computational Complexity Method

Computer Modeling in Engineering & Sciences 2020年第10期125卷 111-123页

作者： Jia Yang Haiyuan Liu Hao He Nankai University School of Electronic Information and Optical EngineeringTianjin Key Laboratory of Optoelectronic Sensor and Sensing Network TechnologyTianjin300350China Hebei University of Technology Tianjin300400China

The prediction of intrinsically disordered proteins is a hot research area in *** to the high cost of experimental methods to evaluate disordered regions of protein sequences,it is becoming increasingly important to predict those regions through computational *** this paper,we developed a novel scheme by employing sequence complexity to calculate six features for each residue of a protein sequence,which includes the Shannon entropy,the topological entropy,the sample entropy and three amino acid preferences including Remark 465,Deleage/Roux,and Bfactor(2STD).Particularly,we introduced the sample entropy for calculating time series complexity by mapping the amino acid sequence to a time series of *** our knowledge,the sample entropy has not been previously used for predicting IDPs and hence is being used for the first time in our *** addition,the scheme used a properly sized sliding window in every protein sequence which greatly improved the prediction ***,we used seven machine learning algorithms and tested with 10-fold cross-validation to get the results on the dataset R80 collected by Yang et *** of the dataset DIS1556 from the Database of Protein Disorder(DisProt)(https://***)containing experimentally determined intrinsically disordered proteins(IDPs).The results showed that k-Nearest Neighbor was more appropriate and an overall prediction accuracy of 92%.Furthermore,our method just used six features and hence required lower computational complexity.

关键词： Bioinformatics intrinsically disordered proteins machine learning algorithms sequences computational complexity

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Study on ultra-precision phase synchronization technique employing phase-locked loop

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optoelectronics Letters 2021年第3期17卷 134-139页

作者： ZHANG Wan-peng WU Hong ZHOU Wei-feng ZHAO Ying-xin LIU Zhi-yang YANG Meng-huan Tianjin Key Laboratory of Optoelectronic Sensor and Sensing Network Technology College of Electronic Information and Optical EngineeringNankai UniversityTianjin 300350China

Microwave-to-optical phase synchronization techniques have attracted growing research interests in recent years. Here, we demonstrate tight, real-time phase synchronization of an optical frequency comb to a rubidium atomic clock. A detailed mathematical model of the phase locking system is developed to optimize its built-in parameters. Based on the model, we fabricate a phase locking circuit with high integration. Once synchronized, the fractional frequency instability of the repetition rate agrees to 6.35×10^(-12) at 1 s and the standard deviation is 1.5 mHz, which indicates the phase synchronization system can implement high-precision stabilization. This integrated stable laser comb should enable a wide range of applications beyond the laboratory.

关键词： synchronization phase locking

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Resolution and contrast enhancement in optical subtraction microscopy with annular aperture

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optoelectronics Letters 2019年第2期15卷 93-97页

作者： LI Zheng-ya WANG Xiang-hui FAN Fei CHENG Jie-rong CHANG Sheng-jiang Tianjin Key Laboratory of Optoelectronic Sensor and Sensing Network Technology Institute of Modern Optics Nankai University

A method for improving lateral resolution and reducing imaging distortion of optical subtraction microscopy is ***, an azimuthally polarized(AP) light is modulated by an annular ***, an image with higher lateral resolution is obtained by subtracting an image obtained by an annular AP beam from an image obtained by a radially polarized *** simulation results demonstrate that compared with the case without the annular aperture, negative side-lobes in the effective point spread function are effectively suppressed, and the imaging quality of subtraction microscopy is obviously enhanced.

关键词： PSF Resolution enhancement subtraction

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Growth of TlBa_2Ca_2Cu_3O_9 Epitaxial Thin Films by Two-Step Method in Argon

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Chinese Physics Letters 2019年第5期36卷 79-83页

作者： Jian Xing Li-Tian Wang Xiao-Xin Gao Xue-Lian Liang Kai-Yong He Ting Xue Sheng-Hui Zhao Jin-Li Zhang Ming He Xin-Jie Zhao Shao-Lin Yan Pei Wang Lu Ji College of Electronic Information and Optical Engineering Nankai UniversityTianjin 300350 Tianjin Key Laboratory of Optoelectronic Sensor and Sensing Network Technology Tianjin 300350 Key Laboratory of Photoelectronic Thin Film Devices and Technology of Tianjin Tianjin 300350 Beijing Institute of Radio Measurement Beijing 100854

TlBa_2 Ca_2 Cu_3 O_9(Tl-1223) films have promising applications due to their high critical temperature and strong magnetic flux pinning. Nevertheless, the preparation of pure phase Tl-1223 film is still a challenge. We successfully fabricate Tl-1223 thin films on LaAlO_3(001) substrates using dc magnetic sputtering and a post annealing two-step method in argon atmosphere. The crystallization temperature of Tl-1223 films in argon is reduced by 100℃ compared to that in oxygen. This greatly reduces the volatilization of Tl and improves the surface morphology of films. The lower annealing temperature can effectively improve the repeatability of the Tl-1223 film preparation. In addition, pure Tl-1223 phase can be obtained in a broad temperature zone,from 790℃ to 830℃. In our study, the films show homogenous and dense surface morphology using the presented method. The best critical temperature of Tl-1223 films is characterized to be 110 K, and the critical current J_c(77 K, 0 T) is up to 2.13 × 106 A/cm^2.

关键词： Ba Cu Ca

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Analysis of base stations deployment on power saving for heterogeneous network 17

Analysis of base stations deployment on power saving for het...

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17th IEEE International Conference on Communication technology, ICCT 2017

作者： Lv, Yuanhong Zhang, Hui Xueming, Sui NanKai University Tianjin Key Laboratory of Optoelectronic Sensor and Sensing Network Technology Tianjin China

ISBN: (纸本)9781509039432

With the increasing of energy consumption in the wireless network, Heterogeneous network (HetNet) is used to improve the capability of communication networks, save transmitting power of base stations (BSs), enhance the coverage of communication network and so on. Designing an energy efficient network should not only consider the energy efficient operation of BSs, but also take the energy efficiency of mobile devices (MDs) into account. This paper considers the energy efficiency of BSs and MDs and studies the power saving of HetNet from a more comprehensive and systematic perspective. This paper mainly analyzes the deployment of a certain number of micro BSs in the region which has a certain number of macro BSs, and compares the power saving indicator at different radius of the micro BSs in three algorithms, which are that the region-based deployment algorithm, the grid-based deployment algorithm and the greedy BSs deployment algorithm. The greedy BSs deployment algorithm is used to determine the most suitable positions of micro BSs, in order to maximize the overall power saving indicator of the entire HetNet. © 2017 IEEE.

关键词： Heterogeneous networks

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Research on Resource Allocation Based on Immune Algorithm in D2D System 19

Research on Resource Allocation Based on Immune Algorithm in...

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19th IEEE International Conference on Communication technology, ICCT 2019

作者： Zheng, Tianyu Zhang, Hui Fei, Lei Li, Luan Nankai University Tianjin Key Laboratory of Optoelectronic Sensor and Sensing Network Technology Tianjin China

ISBN: (纸本)9781728105352

D2D technology is a communication method in which two users can communicate directly by multiplexing cellular channels. Due to the existence of co-channel interference, research on resource allocation is particularly significant. We first describe the D2D communication scenario and discuss the difference of path loss model between D2D users and cellular users, then summarize the problem as an optimization model to maximize the multiplexed channel throughput. According to this optimization goal, a resource allocation algorithm based on immune theory is proposed, which can find the best multiplexed channels for D2D pairs. The simulation results show that the proposed algorithm can effectively improve the channel throughput compared with the existing literature algorithms. © 2019 IEEE.

关键词： Resource allocation

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Laser-tuned whispering gallery modes in silica microbubble resonator integrated with iron oxide particles

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optoelectronics Letters 2021年第3期17卷 129-133页

作者： LIANG Cong-zhou ZHANG Hao WANG Yu-jia WU Ji-xuan LIN Wei LIU Bo LIU Hai-feng Tianjin Key Laboratory of Optoelectronic Sensor and Sensing Network Technology Institute of Modern OpticsNankai UniversityTianjin 300350China Tianjin Key Laboratory of Optoelectronic Detection Technology and Systems College of Electronic and Information EngineeringTianjin Polytechnic UniversityTianjin 300387China

A 473-nm-laser-tuned whispering gallery mode(WGM) silica microbubble resonator integrated with iron oxide particles is demonstrated in this paper. Owing to the photo-induced thermal effect, the WGM resonance wavelength could be tuned by adjusting laser power density of the illuminating light absorbed by the iron oxide particles. A wavelength tuning sensitivity of 0.03 nm/(mW·mm^(-2)) and a tuning range of 0.18 nm are experimentally achieved. Moreover, the influence of ambient temperature on the WGM spectral characteristics is experimentally studied, and a silica-microbubble-based reference scheme is demonstrated to compensate for the temperature-caused resonance wavelength variation. The proposed laser-tuned microresonator has great potential in optical modulation and high-precision optical filtering applications.

关键词： resonator tuning silica

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Single-molecule devices reveal step-by-step dynamics of hydrogen bonds

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Science China Chemistry 2018年第6期61卷 639-640页

作者： Lifa Ni Dong Xiang Takhee Lee Tianjin Key Laboratory of Optoelectronic Sensor and Sensing Network Technology College of Electronic Information and Optical Engineering Nankai University Department of Physics and Astronomy Seoul National University

Intermolecular interactions,including hydrogen bonding,hydrophobic interactions,halogen bonding etc.,are ubiquitous in nature,which play key roles in the basic chemical,physical and biochemical process of *** them,hydrogen bonds are particularly attractive because they dominate many important structures and functions in nature from elegant base-pair interactions in DNAs to sophisticated protein folding and are regarded as an important element in the discovery of new *** better elucidate fundamental mechanisms,

关键词：氢结合单个分子动力学设备相互作用生物化学分子间 DNA

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Simulation and measurement of millimeter-wave radiation from Josephson junction array

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Chinese Physics B 2019年第6期28卷 87-90页

作者： Xin Zhang Sheng-Hui Zhao Li-Tian Wang Jian Xing Sheng-Fang Zhang Xue-Lian Liang Ze He Pei Wang Xin-Jie Zhao Ming He Lu Ji College of Electronic Information and Optical Engineering Nankai UniversityTianjin 300350China Beijing Institute of Radio Measurement Beijing 100854China Key Laboratory of Photoelectronic Thin Film Devices and Technology of Tianjin Tianjin 300350China Tianjin Key Laboratory of Optoelectronic Sensor and Sensing Network Technology Tianjin 300350China

We report the circuit simulations and experiments of millimeter-wave radiation from a high temperature superconducting(HTS) bicrystal Josephson junction(BJJ) array. To study the effects of junction characteristic parameters on radiation properties, new radiation circuit models are proposed in this paper. The series resistively and capacitively shunted junction(RCSJ) models are packaged into a Josephson junction array(JJA) model in the simulation. The current-voltage characteristics(IVCs) curve and radiation peaks are simulated and analyzed by circuit models, which are also observed from the experiment at liquid nitrogen temperature. The experimental radiation linewidth and power are in good agreement with simulated results. The presented circuit models clearly demonstrate that the inconsistency of the JJA will cause a broad linewidth and a low detected power. The junction radiation properties are also investigated at the optimal situation by circuit simulation. The results further confirm that the consistent JJA characteristic parameters can successfully narrow the radiation linewidth and increase the power of junction radiation.

关键词： high temperature superconducting(HTS) Josephson junction array radiation circuit model simulation

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Improved sensing performance of WO_(3) nanoparticles decorated with Ag and Pt nanoparticles

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Rare Metals 2021年第6期40卷 1642-1650页

作者： Dong-Liang Feng Zheng-You Zhu Ling-Ling Du Xia-Xia Xing Chen Wang Jian Chen Yong-Tao Tian Da-Chi Yang Tianjin Key Laboratory of Optoelectronic Sensor and Sensing Network Technology and Department of ElectronicsCollege of Electronic Information and Optical EngineeringNankai UniversityTianjin 300350China School of Physics and Engineering and Key Laboratory of Materials Physics Ministry of EducationZhengzhou UniversityZhengzhou 450001China

Gas sensors built with metal oxide semiconductors have attracted tremendous attention due to the growing demand for the detection of inflammable,explosive and toxic ***,to improve the sensing response,WO_(3) nanoparticles decorated with Ag and Pt bimetals(Ag and Pt/WO_(3) NPs)have been developed via combined hydrolysis and hydrothermal *** sensors prototypes show high response to acetone(Ra/Rg=250@100×10^(-6),140℃),which is 6.1 fold as high as that of the pristine WO_(3) NPs(Ra/Rg=41@100×10^(-6),140℃).Moreover,the recovery time of Ag and Pt/WO_(3) NPs was reduced from 138 to 13 s compared with that of the pristine WO_(3) *** improved acetone sensing performance may be attributed to that the chemical and electronic sensitization of Ag and Pt to WO_(3) NPs increases adsorbed oxygen species,speeds up the reaction and thus boosts the sensing *** strategy that decoration of dual precious metals onto WO_(3) NPs improves the acetone sensing performance may be applied to the gas sensors of other sensing materials.

关键词： WO_(3)nanoparticles Ag and Pt bimetals Acetone sensing Chemical sensitization Recovery time

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