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检索条件"机构=UCSF-UC Berkeley Joint Graduate Program in Bioengineering"
103 条 记 录,以下是31-40 订阅
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De novo protein fold families expand the designable ligand binding site space
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PLoS Computational Biology 2021年 第11期17卷 e1009620-e1009620页
作者: Pan, Xingjie Kortemme, Tanja Department of Bioengineering and Therapeutic Sciences University of California San Francisco San FranciscoCA United States UC Berkeley-UCSF Graduate Program in Bioengineering University of California San Francisco San FranciscoCA United States University of California San Francisco San FranciscoCA United States Chan Zuckerberg Biohub San FranciscoCA United States
A major challenge in designing proteins de novo to bind user-defined ligands with high affinity is finding backbones structures into which a new binding site geometry can be engineered with high precision. Recent adva... 详细信息
来源: 评论
Author Correction: Miniscope3D: optimized single-shot miniature 3D fluorescence microscopy
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Light, science & applications 2023年 第1期12卷 93页
作者: Kyrollos Yanny Nick Antipa William Liberti Sam Dehaeck Kristina Monakhova Fanglin Linda Liu Konlin Shen Ren Ng Laura Waller UCB/UCSF Joint Graduate Program in Bioengineering University of California Berkeley CA 94720 USA. kyrollosyanny@***. Department of Electrical Engineering & Computer Sciences University of California Berkeley CA 94720 USA. naantipa@***. Department of Electrical Engineering & Computer Sciences University of California Berkeley CA 94720 USA. TIPs Department Université libre de Bruxelles (ULB) 1050 Brussels Belgium. UCB/UCSF Joint Graduate Program in Bioengineering University of California Berkeley CA 94720 USA.
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A complete allosteric map of a GTPase switch in its native cellular network
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Cell Systems 2023年 第3期14卷 237-246.e7页
作者: Mathy, Christopher J.P. Mishra, Parul Flynn, Julia M. Perica, Tina Mavor, David Bolon, Daniel N.A. Kortemme, Tanja Department of Bioengineering and Therapeutic Sciences University of California San Francisco San Francisco 94158 CA United States Quantitative Biosciences Institute University of California San Francisco San Francisco 94158 CA United States The UC Berkeley-UCSF Graduate Program in Bioengineering University of California San Francisco San Francisco 94158 CA United States Department of Biochemistry and Molecular Biotechnology University of Massachusetts Medical School Worcester 01605 MA United States Chan Zuckerberg Biohub San Francisco 94158 CA United States School of Life Sciences University of Hyderabad Telangana Hyderabad India
Allosteric regulation is central to protein function in cellular networks. A fundamental open question is whether cellular regulation of allosteric proteins occurs only at a few defined positions or at many sites dist... 详细信息
来源: 评论
Fourier diffuserscope: Single-shot 3d fourier light field microscopy with a diffuser
arXiv
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arXiv 2020年
作者: Liu, Fanglin Linda Grace, K.U.O. Antipa, Nick Yanny, Kyrollos Waller, Laura Electrical Engineering and Computer Sciences University of California Berkeley94709 United States UCB/UCSF Joint Graduate Program in Bioengineering University of California BerkeleyCA94709 United States
Light field microscopy (LFM) uses a microlens array (MLA) near the sensor plane of a microscope to achieve single-shot 3D imaging of a sample, without any moving parts. Unfortunately, the 3D capability of LFM comes wi... 详细信息
来源: 评论
Spectral DiffuserCam: lensless snapshot hyperspectral imaging with a spectral filter array
arXiv
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arXiv 2020年
作者: Monakhova, Kristina Yanny, Kyrollos Aggarwal, Neerja Waller, Laura Department of Electrical Engineering & Computer Sciences University of California BerkeleyCA94720 United States UCB/UCSF Joint Graduate Program in Bioengineering University of California BerkeleyCA94720 United States
Hyperspectral imaging is useful for applications ranging from medical diagnostics to crop monitoring;however, traditional scanning hyperspectral imagers are prohibitively slow and expensive for widespread adoption. Sn... 详细信息
来源: 评论
Osteocyte dysfunction promotes osteoarthritis through MMP13-dependent suppression of subchondral bone homeostasis
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Bone Research 2019年 第4期7卷 354-370页
作者: Courtney MMazur Jonathon JWoo Cristal SYee Aaron JFields Claire Acevedo Karsyn NBailey Serra Kaya Tristan WFowler Jeffrey CLotz Alexis Dang Alfred CKuo Thomas PVail Tamara Alliston Department of Orthopaedic Surgery University of CaliforniaSan FranciscoCA 94143USA UC Berkeley-UCSF Graduate Program in Bioengineering San FranciscoCA 94143USA Department of Mechanical Engineering University of UtahSalt Lake CityUT 84112USA San Francisco Veterans Affairs Medical Center San FranciscoCA 94121USA
Osteoarthritis(OA),long considered a primary disorder of articular cartilage,is commonly associated with subchondral bone ***,the cellular mechanisms responsible for changes to subchondral bone in OA,and the extent to... 详细信息
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Accessible and accurate cytometry analysis of adherent cells using fluorescence microscopes
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Scientific Reports 2025年 第1期15卷 1-9页
作者: Daniel Foyt Yiming Kuang Klaus Yserentant Bo Huang Samma Rehem UCSF-UC Berkeley Joint Graduate Program in Bioengineering University of California San Francisco San Francisco CA 94143 USA Department of Pharmaceutical Chemistry University of California San Francisco San Francisco CA 94143 USA Department of Biochemistry and Biophysics University of California San Francisco San Francisco CA 94143 USA Chan Zuckerberg Biohub San Francisco San Francisco CA 94158 USA Barnard College of Columbia University New York City NY 10027 USA
We have developed a method along with a Python-based analysis tool to capture images and produce flow-cytometry-like data for adherent cell culture utilizing simple accessible microscopes. Leveraging the recently deve...
来源: 评论
A metabolite specific 3D stack-of-spiral bSSFP sequence for improved lactate imaging in hyperpolarized [1-13C]pyruvate studies on a 3T clinical scanner
arXiv
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arXiv 2020年
作者: Tang, Shuyu Bok, Robert Qin, Hecong Reed, Galen VanCriekinge, Mark Santos, Romelyn Delos Overall, William Santos, Juan Gordon, Jeremy Wang, Zhen Jane Vigneron, Daniel B. Larson, Peder E.Z. UC Berkeley-UCSF Graduate Program in Bioengineering University of California San Francisco University of California Berkeley United States Department of Radiology and Biomedical Imaging University of California - San Francisco San FranciscoCA United States HeartVista Los AltosCA United States
Purpose: The balanced steady-state free precession sequence has been previously explored to improve the efficient use of non-recoverable hyperpolarized 13C magnetization, but suffers from poor spectral selectivity and... 详细信息
来源: 评论
Resistive-pulse sensing tumor-derived exosome detection device  22
Resistive-pulse sensing tumor-derived exosome detection devi...
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22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018
作者: Carey, Thomas R. Yu, Connie W. Hall, Jennifer Sohn, Lydia L. UC Berkeley UCSF Graduate Program in Bioengineering United States UC Berkeley Bioengineering United States UC Berkeley Molecular and Cell Biology United States UC Berkeley Mechanical Engineering United States
We present the theory, design, and proof-of-concept demonstration of a tumor-derived exosome detection platform that enables non-invasive, cost-effective, point-of-care cancer screening. Our platform detects exosomes ... 详细信息
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A Regional bolus tracking and Real-time B1 Calibration method for Hyperpolarized 13C MRI
arXiv
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arXiv 2020年
作者: Tang, Shuyu Milshteyn, Eugene Reed, Galen Gordon, Jeremy Bok, Robert Zhu, Xucheng Zhu, Zihan Vigneron, Daniel B. Larson, Peder E.Z. UC Berkeley-UCSF Graduate Program in Bioengineering University of California San Francisco United States University of California Berkeley United States Department of Radiology and Biomedical Imaging University of California - San Francisco San FranciscoCA United States HeartVista Los AltosCA United States
Purpose: Acquisition timing and B1 calibration are two key factors that affect the quality and accuracy of hyperpolarized 13C MRI. The goal of this project was to develop a new approach using regional bolus tracking t... 详细信息
来源: 评论