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Publisher Correction: The ENCODE Imputation Challenge: a critical assessment of methods for cross-cell type imputation of epigenomic profiles

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Genome biology 2025年第1期26卷 31页

作者： Jacob Matthew Schreiber Carles A Boix Jin Wook Lee Hongyang Li Yuanfang Guan Chun-Chieh Chang Jen-Chien Chang Alex Hawkins-Hooker Bernhard Schölkopf Gabriele Schweikert Mateo Rojas Carulla Arif Canakoglu Francesco Guzzo Luca Nanni Marco Masseroli Mark James Carman Pietro Pinoli Chenyang Hong Kevin Y Yip Jefrey P Spence Sanjit Singh Batra Yun S Song Shaun Mahony Zheng Zhang Wuwei Tan Yang Shen Yuanfei Sun Minyi Shi Jessika Adrian Richard S Sandstrom Nina P Farrell Jessica M Halow Kristen Lee Lixia Jiang Xinqiong Yang Charles B Epstein J Seth Strattan Bradley E Bernstein Michael P Snyder Manolis Kellis William S Noble Anshul Bharat Kundaje Department of Genetics Stanford University Stanford CA USA. jmschreiber91@***. Computer Science and Artificial Intelligence Laboratory Massachusetts Institute of Technology Cambridge MA USA. Department of Genetics Stanford University Stanford CA USA. Department of Computational Medicine and Bioinformatics University of Michigan Ann Arbor MI USA. Department of Research and Development DeepSeq.AI San Francisco CA USA. RIKEN Center for Integrative Medical Sciences Yokohama Japan. Department of Empirical Inference Max Planck Institute for Intelligent Systems Stuttgart Germany. School of Life Sciences University of Dundee Dundee UK. Department of Electronics Information and Bioengineering Politecnico Di Milano Milan Italy. Department of Computational Biology University of Lausanne Lausanne Switzerland. Department of Computer Science and Engineering The Chinese University of Hong Kong Sha Tin Hong Kong. Sanford Burnham Prebys Medical Discovery Institute San Diego CA USA. Department of Electrical Engineering and Computer Sciences University of California Berkeley Berkeley CA USA. Department of Statistics University of California Berkeley Berkeley CA USA. Department of Biochemistry & Molecular Biology Center for Eukaryotic Gene Regulation Pennsylvania State University University Park PA USA. Department of Statistics Pennsylvania State University University Park PA USA. Department of Electrical and Computer Engineering Texas A&M University College Station TX USA. Altius Institute Seattle WA USA. Epigenomics Program The Broad Institute of MIT and Harvard Cambridge MA USA. Department of Genome Sciences University of Washington Seattle WA USA. Department of Computer Science Stanford University Stanford CA USA.

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Effect of Zeeman coupling on the Majorana vortex modes in iron-based topological superconductors

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Physical Review B 2020年第2期101卷 020504(R)-020504(R)页

作者： Areg Ghazaryan P. L. S. Lopes Pavan Hosur Matthew J. Gilbert Pouyan Ghaemi IST Austria (Institute of Science and Technology Austria) Am Campus 1 3400 Klosterneuburg Austria Stewart Blusson Quantum Matter Institute University of British Columbia Vancouver British Columbia Canada V6T 1Z4 Department of Physics University of Houston Houston Texas 77204 USA Micro and Nanotechnology Laboratory University of Illinois at Urbana-Champaign Urbana Illinois 61801 USA Department of Electrical and Computer Engineering University of Illinois at Urbana-Champaign Urbana Illinois 61801 USA Department of Electrical Engineering Stanford University Stanford California 94305 USA Physics Department City College of the City University of New York New York New York 10031 USA Physics Program Graduate Center of the City University of New York New York 10031 USA

In the superconducting regime of FeTe(1−x)Sex, there exist two types of vortices which are distinguished by the presence or absence of zero-energy states in their core. To understand their origin, we examine the interplay of Zeeman coupling and superconducting pairings in three-dimensional metals with band inversion. Weak Zeeman fields are found to suppress intraorbital spin-singlet pairing, known to localize the states at the ends of the vortices on the surface. On the other hand, an orbital-triplet pairing is shown to be stable against Zeeman interactions, but leads to delocalized zero-energy Majorana modes which extend through the vortex. In contrast, the finite-energy vortex modes remain localized at the vortex ends even when the pairing is of orbital-triplet form. Phenomenologically, this manifests as an observed disappearance of zero-bias peaks within the cores of topological vortices upon an increase of the applied magnetic field. The presence of magnetic impurities in FeTe(1−x)Sex, which are attracted to the vortices, would lead to such Zeeman-induced delocalization of Majorana modes in a fraction of vortices that capture a large enough number of magnetic impurities. Our results provide an explanation for the dichotomy between topological and nontopological vortices recently observed in FeTe(1−x)Sex.

关键词： Majorana bound states Topological superconductors Iron-based superconductors

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Quasielectrostatic Wave Propagation Beyond the Delay-Bandwidth Limit in Switched Networks

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Physical Review X 2019年第3期9卷 031015-031015页

作者： Mykhailo Tymchenko Dimitrios Sounas Aravind Nagulu Harish Krishnaswamy Andrea Alù Department of Electrical and Computer Engineering The University of Texas at Austin 1 University Station C0803 Austin Texas 78712 USA Department of Electrical and Computer Engineering Wayne State University Detroit Michigan 48202 USA Department of Electrical Engineering Columbia University 1300 South West Mudd 500 West 120th Street New York New York 10027 USA Photonics Initiative Advanced Science Research Center City University of New York New York New York 10031 USA Physics Program Graduate Center City University of New York New York New York 10026 USA Department of Electrical Engineering City College of New York New York New York 10031 USA

The delay-bandwidth limit implies a stringent trade-off between the time delay, bandwidth, and propagation distance of an electromagnetic signal. Here, we show that temporal modulation can overcome this constraint, enabling extremely broadband wave propagation with close-to-zero group velocity dispersion in switched multipath electronic networks. Contrary to time-invariant waveguides, in which wave propagation implies a delicate balance between electric and magnetic stored energies, in such modulated networks the stored energy is largely electrostatic in nature. We show that in this case the phase and group velocities become independent of the properties of their constituent elements, and they are controlled only by the modulation scheme. Based on these findings, we provide practical designs of deeply subwavelength CMOS-compatible reciprocal and nonreciprocal microwave components, such as delay lines, phase shifters, couplers, and circulators. The obtained results also explicitly show that temporally modulated systems are not bound by constraints of time-invariant systems and can achieve arbitrarily large delay-bandwidth products.

关键词： Metamaterials

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Building a quantum engineering undergraduate program

arXiv

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arXiv 2021年

作者： Asfaw, Abraham Blais, Alexandre Brown, Kenneth R. Candelaria, Jonathan Cantwell, Christopher Carr, Lincoln D. Combes, Joshua Debroy, Dripto M. Donohue, John M. Economou, Sophia E. Edwards, Emily Fox, Michael F.J. Girvin, Steven M. Ho, Alan Hurst, Hilary M. Jacob, Zubin Johnson, Blake R. Johnston-Halperin, Ezekiel Joynt, Robert Kapit, Eliot Klein-Seetharaman, Judith Laforest, Martin Lewandowski, H.J. Lynn, Theresa W. McRae, Corey Rae H. Merzbacher, Celia Michalakis, Spyridon Narang, Prineha Oliver, William D. Palsberg, Jens Pappas, David P. Raymer, Michael G. Reilly, David J. Saffman, Mark Searles, Thomas A. Shapiro, Jeffrey H. Singh, Chandralekha IBM Quantum IBM T. J. Watson Research Center Yorktown HeightsNY United States Institut Quantique Département de Physique Université de Sherbrooke SherbrookeQCJ1K 2R1 Canada Canadian Institute for Advanced Research TorontoONM5G 1M1 Canada The Duke Quantum Center Department of Physics Department of Electrical and Computer Engineering Department of Chemistry Duke University DurhamNC27708 United States SystemX Program Department of Electrical Engineering Stanford University StanfordCA94305 United States Department of Physics and Astronomy University of Southern California Los AngelesCA90089 United States The Quantum Engineering Program Department of Physics Colorado School of Mines GoldenCO80401 United States The Department of Electrical Computer and Energy Engineering University of Colorado Boulder BoulderCO80309 United States The Institute for Quantum Computing University of Waterloo WaterlooONN2L 3G1 Canada The Department of Physics Virginia Tech BlacksburgVA24061 United States The IQUIST University of Illinois Urbana-Champaign UrbanaIL61801 United States JILA National Institute of Standards and Technology The University of Colorado BoulderCO80309 United States Department of Physics University of Colorado Boulder BoulderCO80309 United States The Department of Physics Imperial College London Prince Consort Road LondonSW7 2AZ United Kingdom The Yale Quantum Institute Department of Physics Yale University New HavenCT06520 United States Google Research VeniceCA90291 United States The Department of Physics & Astronomy San José State University San JoséCA95192 United States The School of Electrical and Computer Engineering Purdue University Indiana West Lafayatte47907 United States The Department of Physics The Ohio State University ColumbusOH43210 United States The Department of Physics University of Wisconsin-Madison 1150 University Avenue MadisonWI53706 United States The Quantitative Biosciences and Engineering

The rapidly growing quantum information science and engineering (QISE) industry will require both quantum-aware and quantum-proficient engineers at the bachelor's level. We provide a roadmap for building a quantum engineering education program to satisfy this need. For quantum-aware engineers, we describe how to design a first quantum engineering course accessible to all STEM students. For the education and training of quantum-proficient engineers, we detail both a quantum engineering minor accessible to all STEM majors, and a quantum track directly integrated into individual engineering majors. We propose that such programs typically require only three or four newly developed courses that complement existing engineering and science classes available on most larger campuses. We describe a conceptual quantum information science course for implementation at any post-secondary institution, including community colleges and military schools. QISE presents extraordinary opportunities to work towards rectifying issues of inclusivity and equity that continue to be pervasive within engineering. We present a plan to do so and describe how quantum engineering education presents an excellent set of education research opportunities. Finally, we outline a hands-on training plan on quantum hardware, a key component of any quantum engineering program, with a variety of technologies including optics, atoms and ions, cryogenic and solid-state technologies, nanofabrication, and control and readout electronics. Our recommendations provide a flexible framework that can be tailored for academic institutions ranging from teaching and undergraduate-focused two- and four-year colleges to research-intensive universities. © 2021, CC BY.

关键词： engineering education

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Coupling rendering and generative adversarial networks for artificial SAS image generation

arXiv

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arXiv 2019年

作者： Reed, Albert Gerg, Isaac D. McKay, John D. Brown, Daniel C. Williams, David P. Jayasuriya, Suren School of Electrical Computer & Energy Engineering Arizona State University TempeAZ United States School of Arts Media & Engineering Arizona State University TempeAZ United States Applied Research Laboratory Pennsylvania State University State College PA United States Graduate Program in Acoustics Pennsylvania State University State College PA United States School of Electrical Engineering and Computer Science Pennsylvania State University State College PA United States NATO STO Centre for Maritime Research & Experimentation La Spezia Italy

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Blueshift: Rebalancing engineering engagement, integrity, and learning outcomes across an electronically-enabled remediation hierarchy

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computers in Education Journal 2019年第1期10卷 1-12页

作者： DeMara, Ronald F. Sheikhfaal, Shadi Wilder, Paul J. Chen, Baiyun Hartshorne, Richard Department of Electrical Engineering and Computer Science University of Central Florida OrlandoFL32816 United States Department of Engineering Computer Program and Technology Valencia College OrlandoFL32811 United States Center for Distributed Learning University of Central Florida OrlandoFL32816 United States Division Dean for Learning Sciences Educational Research University of Central Florida OrlandoFL32816 United States

With a growing number of enrollments in engineering programs, more time and energy for tutoring and grading exams/quizzes is necessary. The BLUESHIFT framework utilizes a synergistic combination of faculty, Graduate Teaching Assistants, and educational technologies to provide reliable approaches to not only meet the increased time, cost, and energy efficiency needed for increasing numbers of engineering students, but also to focus on improving the quality of education, skills, and employability of our graduates in computing-related fields. An Evaluation and Proficiency Center (EPC) has been piloted at a large state university, where key elements of the BLUESHIFT learning flow have been integrated into selected undergraduate engineering courses. The EPC integrates computer-based evaluation with a close-knit review and learning cycle based on directed and open tutoring. This approach has received overwhelmingly positive responses from students regarding the effectiveness of pedagogical approaches (i.e., Exemplar Vignettes, content tutoring), assessment models (i.e., electronically delivered quizzes, flexible scheduling, use of testing center), and tutoring strategies (i.e., self-paced, exam results review). Survey results have been positive with respect to student perceptions across a variety of perspectives compared to paper-based delivery. In this manuscript, the BLUESHIFT framework and process, as well as results collected from student performance and perceptions of the initial implementation, will be addressed. © 2019 American Society for engineering Education. All rights reserved.

关键词： Students

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Exciton Localization of High-Quality ZnO/Mg_xZn_1-xO Multiple Quantum Wells on Si (111) with a Y₂O₃ Buffer Layer (vol 1, pg 3829, 2018)

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ACS APPLIED NANO MATERIALS 2018年第10期1卷 5958-5958页

作者： Liu, Wei-Rein Huang, Wei-Lun Wu, Yung-Chi Lai, Liang-Hsun Hsu, Chia-Hung Hsieh, Wen-Feng Chiang, Tsung-Hung Wan, H. W. Hong, M. Kao, J. National Synchrotron Radiation Research Center Hsinchu 30076 Taiwan Program for Science and Technology of Accelerator Light Source National Chiao Tung University Hsinchu 30010 Taiwan Department of Photonics College of Electrical and Computer Engineering National Chiao Tung University Hsinchu 30010 Taiwan Department of Photonics College of Electrical and Computer Engineering National Chiao Tung University Hsinchu 30010 Taiwan Department of Materials Science & Engineering National Tsing Hua University Hsinchu 30013 Taiwan Graduate Institute of Applied Physics and Department of Physics National Taiwan University Taipei 10617 Taiwan Department of Physics National Tsing Hua University Hsinchu 30013 Taiwan

We report the structural and optical properties of ten-period ZnO/MgxZn1–xO multiple quantum wells (MQWs) prepared on the most widely used semiconductor material, Si. The introduction of a nanometer thick high-k Y2O3transition layer between Si (111) substrate and a ZnO buffer layer significantly improves the structural perfection of the MQWs grown on top of it. The high structural quality of the ZnO/MgxZn1–xO MQWs is evidenced by the appearance of pronounced high order satellite peaks in X-ray crystal truncation rods; high resolution cross-sectional transmission electron microscopy images also confirmed the regularly arranged well and barrier layers. When the well width is less than ∼2.7 nm, the quantum-confined Stark effect in MQWs can be negligible. Not only the increasing exciton-binding energy but also reducing exciton–phonon coupling determined in temperature-dependent photoluminescence spectra indicate quantum-size effect. Our results demonstrate that ZnO/MgxZn1–xO MQWs integrated on Si have great potential in UV optoelectronic device applications.

关键词： Excitons Phonons Oxides Binding energy Layers

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Development of a smartphone-based app for determination of formaldehyde concentration indoors 15

Development of a smartphone-based app for determination of f...

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15th Conference of the International Society of Indoor Air Quality and Climate, INDOOR AIR 2018

作者： Zhang, Siyang Shapiro, Nicholas Gehrke, Gretchen Castner, Jessica Liu, Zhenlei Guo, Beverly Zhang, Jianshun Haines, Sarah Kormos, David Frey, Paige Qin, Rongjun Dannemiller, Karen C. Department of Computer Science and Engineering Ohio State University United States Public Laboratory for Open Technology and Science Department of Mechanical and Aerospace Engineering Syracuse University Environmental Science Graduate Program Ohio State University United States Department of Civil Environmental and Geodetic Engineering College of Engineering Ohio State University United States Strand Associates Incorporated Department of Electrical and Computer Engineering Ohio State University United States Department of Environmental Health Sciences College of Public Health Ohio State University United States

ISBN: (纸本)9781713826514

Formaldehyde is a ubiquitous contaminant in the indoor environment that is both a carcinogen and irritant. The goal of this project is to develop a smartphone-based app for use by citizen scientists or researchers that can be paired with low-cost colorimetric badges for detection of indoor formaldehyde. We conducted both national and geographically-targeted surveys prior to app design. We have subsequently developed the app and conducted a beta test. Surveys of 147 individuals indicated broad public interest in formaldehyde testing using smartphone technology. Testing of the badges indicated consistent change in illumination with increasing formaldehyde exposure. Beta testing indicated users were able to navigate the existing app, and highlighted areas for improvement including incorporation of public surveys. Planned future analysis includes extensive calibration testing and a community-based field test. © 2018 15th Conference of the International Society of Indoor Air Quality and Climate, INDOOR AIR 2018. All rights reserved.

关键词： Formaldehyde

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Telecommunication-wavelength lasing in er-doped gan multiple quantum wells at room temperature

Telecommunication-wavelength lasing in er-doped gan multiple...

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Advanced Solid State Lasers, ASSL 2018

作者： Ho, V.X. Al Tahtamouni, T.M. Wang, Y. Jiang, H.X. Lin, J.Y. Zavada, J.M. Vinh, N.Q. Department of Physics Center for Soft Matter and Biological Physics Virginia Tech BlacksburgVA24061 United States Materials Science and Technology Program College of Arts and Sciences Qatar University Doha2713 Qatar Department of Electrical and Computer Engineering Texas Tech University LubbockTX79409 United States Department of Electrical and Computer Engineering New York University BrooklynNY11201 United States

We report the realization of room-temperature, stimulated-emission in Er-doped-GaN multiple-quantum-wells at the 1.5-µm. Structures were grown by MOCVD and lasing was confirmed by threshold-behaviors of emission-... 详细信息

ISBN: (纸本)9781943580484

关键词： Semiconductor quantum wells

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Graphene composites with dual functionality: electromagnetic shielding and thermal management

arXiv

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arXiv 2018年

作者： Kargar, Fariborz Barani, Zahra Balinskiy, Michael G. Magana, Andres Sanchez Lewis, Jacob S. Balandin, Alexander A. Center Department of Electrical and Computer Engineering Materials Science and Engineering Program Bourns College of Engineering University of California RiversideCA92521 United States

We report on the synthesis and characterization of the epoxy-based composites with the few-layer graphene fillers, which are capable of the duel functional applications. It was found that composites with the certain types of few-layer graphene fillers reveal an efficient total electromagnetic interference shielding, SEtot~45 dB, in the important X-band frequency range, f = 8.2 GHz − 12.4 GHz, while simultaneously providing the high thermal conductivity, K ≈ 8 Wm−1K−1, which is a factor of ×35 larger than that of the base matrix material. The efficiency of the dual functional application depends on the filler characteristics: thickness, lateral dimensions, aspect ratio and concentration. Graphene loading fractions above the percolation threshold allow for strong enhancement of both the electromagnetic interference shielding and heat conduction properties. Interestingly, graphene composites can block the electromagnetic energy even below the percolation threshold, remaining electrically insulating, which is an important feature for some types of thermal interface materials. The dual functionality of the graphene composites can substantially improve the electromagnetic shielding and thermal management of the airborne systems while simultaneously reducing their weight and cost. Copyright © 2018, The Authors. All rights reserved.

关键词： Thermal conductivity

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