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Dark Energy Survey Year 3 results: Cosmological constraints from galaxy clustering and weak lensing

Physical Review D 2022年第2期105卷 023520-023520页

作者： T. M. C. Abbott M. Aguena A. Alarcon S. Allam O. Alves A. Amon F. Andrade-Oliveira J. Annis S. Avila D. Bacon E. Baxter K. Bechtol M. R. Becker G. M. Bernstein S. Bhargava S. Birrer J. Blazek A. Brandao-Souza S. L. Bridle D. Brooks E. Buckley-Geer D. L. Burke H. Camacho A. Campos A. Carnero Rosell M. Carrasco Kind J. Carretero F. J. Castander R. Cawthon C. Chang A. Chen R. Chen A. Choi C. Conselice J. Cordero M. Costanzi M. Crocce L. N. da Costa M. E. da Silva Pereira C. Davis T. M. Davis J. De Vicente J. DeRose S. Desai E. Di Valentino H. T. Diehl J. P. Dietrich S. Dodelson P. Doel C. Doux A. Drlica-Wagner K. Eckert T. F. Eifler F. Elsner J. Elvin-Poole S. Everett A. E. Evrard X. Fang A. Farahi E. Fernandez I. Ferrero A. Ferté P. Fosalba O. Friedrich J. Frieman J. García-Bellido M. Gatti E. Gaztanaga D. W. Gerdes T. Giannantonio G. Giannini D. Gruen R. A. Gruendl J. Gschwend G. Gutierrez I. Harrison W. G. Hartley K. Herner S. R. Hinton D. L. Hollowood K. Honscheid B. Hoyle E. M. Huff D. Huterer B. Jain D. J. James M. Jarvis N. Jeffrey T. Jeltema A. Kovacs E. Krause R. Kron K. Kuehn N. Kuropatkin O. Lahav P.-F. Leget P. Lemos A. R. Liddle C. Lidman M. Lima H. Lin N. MacCrann M. A. G. Maia J. L. Marshall P. Martini J. McCullough P. Melchior J. Mena-Fernández F. Menanteau R. Miquel J. J. Mohr R. Morgan J. Muir J. Myles S. Nadathur A. Navarro-Alsina R. C. Nichol R. L. C. Ogando Y. Omori A. Palmese S. Pandey Y. Park F. Paz-Chinchón D. Petravick A. Pieres A. A. Plazas Malagón A. Porredon J. Prat M. Raveri M. Rodriguez-Monroy R. P. Rollins A. K. Romer A. Roodman R. Rosenfeld A. J. Ross E. S. Rykoff S. Samuroff C. Sánchez E. Sanchez J. Sanchez D. Sanchez Cid V. Scarpine M. Schubnell D. Scolnic L. F. Secco S. Serrano I. Sevilla-Noarbe E. Sheldon T. Shin M. Smith M. Soares-Santos E. Suchyta M. E. C. Swanson M. Tabbutt G. Tarle D. Thomas C. To A. Troja M. A. Troxel D. L. Tucker I. Tutusaus T. N. Varga A. R. Walker N. Weaverdyck R. Wechsler J. Weller B. Yanny B. Yin Y. Zhang J. Zuntz Cerro Tololo Inter-American Observatory NSF’s National Optical-Infrared Astronomy Research Laboratory Casilla 603 La Serena Chile Laboratório Interinstitucional de e-Astronomia—LIneA Rua Gal. José Cristino 77 Rio de Janeiro RJ—20921-400 Brazil Argonne National Laboratory 9700 South Cass Avenue Lemont Illinois 60439 USA Fermi National Accelerator Laboratory P. O. Box 500 Batavia Illinois 60510 USA Department of Physics University of Michigan Ann Arbor Michigan 48109 USA Instituto de Física Teórica Universidade Estadual Paulista São Paulo 01140-070 Brazil Kavli Institute for Particle Astrophysics and Cosmology P. O. Box 2450 Stanford University Stanford California 94305 USA Instituto de Fisica Teorica UAM/CSIC Universidad Autonoma de Madrid 28049 Madrid Spain Institute of Cosmology and Gravitation University of Portsmouth Portsmouth PO1 3FX United Kingdom Institute for Astronomy University of Hawai’i 2680 Woodlawn Drive Honolulu Hawaii 96822 USA Physics Department 2320 Chamberlin Hall University of Wisconsin-Madison 1150 University Avenue Madison Wisconsin 53706-1390 USA Department of Physics and Astronomy University of Pennsylvania Philadelphia Pennsylvania 19104 USA Department of Physics and Astronomy Pevensey Building University of Sussex Brighton BN1 9QH United Kingdom Graduate School of Education Stanford University 160 450 Serra Mall Stanford California 94305 USA Department of Physics Northeastern University Boston Massachusetts 02115 USA Laboratory of Astrophysics École Polytechnique Fédérale de Lausanne (EPFL) Observatoire de Sauverny 1290 Versoix Switzerland Instituto de Física Gleb Wataghin Universidade Estadual de Campinas 13083-859 Campinas SP Brazil Jodrell Bank Center for Astrophysics School of Physics and Astronomy University of Manchester Oxford Road Manchester M13 9PL United Kingdom Department of Physics and Astronomy University College London Gower Street London WC1E 6BT United Kingdom Department of Astronomy and Astroph

We present the first cosmology results from large-scale structure using the full 5000 deg2 of imaging data from the Dark Energy Survey (DES) data Release 1. We perform an analysis of large-scale structure combining three two-point correlation functions (3×2pt): (i) cosmic shear using 100 million source galaxies, (ii) galaxy clustering, and (iii) the cross-correlation of source galaxy shear with lens galaxy positions, galaxy–galaxy lensing. To achieve the cosmological precision enabled by these measurements has required updates to nearly every part of the analysis from DES Year 1, including the use of two independent galaxy clustering samples, modeling advances, and several novel improvements in the calibration of gravitational shear and photometric redshift inference. The analysis was performed under strict conditions to mitigate confirmation or observer bias; we describe specific changes made to the lens galaxy sample following unblinding of the results and tests of the robustness of our results to this decision. We model the data within the flat ΛCDM and wCDM cosmological models, marginalizing over 25 nuisance parameters. We find consistent cosmological results between the three two-point correlation functions; their combination yields clustering amplitude S8=0.776−0.017+0.017 and matter density Ωm=0.339−0.031+0.032 in ΛCDM, mean with 68% confidence limits; S8=0.775−0.024+0.026, Ωm=0.352−0.041+0.035, and dark energy equation-of-state parameter w=−0.98−0.20+0.32 in wCDM. These constraints correspond to an improvement in signal-to-noise of the DES Year 3 3×2pt data relative to DES Year 1 by a factor of 2.1, about 20% more than expected from the increase in observing area alone. This combination of DES data is consistent with the prediction of the model favored by the Planck 2018 cosmic microwave background (CMB) primary anisotropy data, which is quantified with a probability-to-exceed p=0.13–0.48. We find better agreement between DES 3×2pt and Planck than in DES Y1

关键词： Cosmological parameters Cosmology Dark energy Dark matter Large scale structure of the Universe

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Author Correction: Common variants in Alzheimer's disease and risk stratification by polygenic risk scores

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Nature communications 2023年第1期14卷 716页

作者： Itziar de Rojas Sonia Moreno-Grau Niccolo Tesi Benjamin Grenier-Boley Victor Andrade Iris E Jansen Nancy L Pedersen Najada Stringa Anna Zettergren Isabel Hernández Laura Montrreal Carmen Antúnez Anna Antonell Rick M Tankard Joshua C Bis Rebecca Sims Céline Bellenguez Inés Quintela Antonio González-Perez Miguel Calero Emilio Franco-Macías Juan Macías Rafael Blesa Laura Cervera-Carles Manuel Menéndez-González Ana Frank-García Jose Luís Royo Fermin Moreno Raquel Huerto Vilas Miquel Baquero Mónica Diez-Fairen Carmen Lage Sebastián García-Madrona Pablo García-González Emilio Alarcón-Martín Sergi Valero Oscar Sotolongo-Grau Abbe Ullgren Adam C Naj Afina W Lemstra Alba Benaque Alba Pérez-Cordón Alberto Benussi Alberto Rábano Alessandro Padovani Alessio Squassina Alexandre de Mendonça Alfonso Arias Pastor Almar A L Kok Alun Meggy Ana Belén Pastor Ana Espinosa Anaïs Corma-Gómez Angel Martín Montes Ángela Sanabria Anita L DeStefano Anja Schneider Annakaisa Haapasalo Anne Kinhult Ståhlbom Anne Tybjærg-Hansen Annette M Hartmann Annika Spottke Arturo Corbatón-Anchuelo Arvid Rongve Barbara Borroni Beatrice Arosio Benedetta Nacmias Børge G Nordestgaard Brian W Kunkle Camille Charbonnier Carla Abdelnour Carlo Masullo Carmen Martínez Rodríguez Carmen Muñoz-Fernandez Carole Dufouil Caroline Graff Catarina B Ferreira Caterina Chillotti Chandra A Reynolds Chiara Fenoglio Christine Van Broeckhoven Christopher Clark Claudia Pisanu Claudia L Satizabal Clive Holmes Dolores Buiza-Rueda Dag Aarsland Dan Rujescu Daniel Alcolea Daniela Galimberti David Wallon Davide Seripa Edna Grünblatt Efthimios Dardiotis Emrah Düzel Elio Scarpini Elisa Conti Elisa Rubino Ellen Gelpi Eloy Rodriguez-Rodriguez Emmanuelle Duron Eric Boerwinkle Evelyn Ferri Fabrizio Tagliavini Fahri Küçükali Florence Pasquier Florentino Sanchez-Garcia Francesca Mangialasche Frank Jessen Gaël Nicolas Geir Selbæk Gemma Ortega Geneviève Chêne Georgios Hadjigeorgiou Giacomina Rossi Gianfranco Spalletta Giorgio Giaccone Giulia Grande Giuliano Binetti Goran Papenberg Harald Hampel Research Center and Memory clinic Fundació ACE Institut Català de Neurociències Aplicades Universitat Internacional de Catalunya Barcelona Spain. CIBERNED Network Center for Biomedical Research in Neurodegenerative Diseases National Institute of Health Carlos III Madrid Spain. Alzheimer Center Amsterdam Department of Neurology Amsterdam Neuroscience Vrije Universiteit Amsterdam Amsterdam UMC Amsterdam The Netherlands. Section Genomics of Neurodegenerative Diseases and Aging Department of Clinical Genetics Vrije Universiteit Amsterdam Amsterdam UMC Amsterdam The Netherlands. Delft Bioinformatics Lab Delft Univeristy of Technology Delft The Netherlands. Univ. Lille Inserm Institut Pasteur de Lille CHU Lille U1167-Labex DISTALZ-RID-AGE-Risk Factors and Molecular Determinants of Aging-Related Diseases Lille France. Division of Neurogenetics and Molecular Psychiatry Department of Psychiatry and Psychotherapy University of Cologne Medical Faculty Cologne Germany. Department of Neurodegenerative diseases and Geriatric Psychiatry University Clinic Bonn Bonn Germany. Department of Complex Trait Genetics Center for Neurogenomics and Cognitive Research Amsterdam Neuroscience VU University Amsterdam The Netherlands. Department of Medical Epidemiology and Biostatistics Karolinska Institutet Stockholm Sweden. Amsterdam UMC-Vrije Universiteit Amsterdam Department of Epidemiology and Data Science Amsterdam Public Health Research Institute Amsterdam The Netherlands. Neuropsychiatric Epidemiology Unit Department of Psychiatry and Neurochemistry Institute of Neuroscience and Physiology Sahlgrenska Academy Centre for Ageing and Health (AgeCap) University of Gothenburg Gothenburg Sweden. Unidad de Demencias Hospital Clínico Universitario Virgen de la Arrixaca Murcia Spain. Alzheimer's disease and other cognitive disorders unit. Service of Neurology Hospital Clínic of Barcelona. Institut d'Investigacions Biomèdiques August Pi i Sunyer University of Barcelona Barcelona Spain

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Advances in understanding high-mass X-ray binaries with INTEGRAL and Future Directions

arXiv

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arXiv 2020年

作者： Kretschmar, Peter Fürst, Felix Sidoli, Lara Bozzo, Enrico Alfonso-Garzón, Julia Bodaghee, Arash Chaty, Sylvain Chernyakova, Masha Ferrigno, Carlo Manousakis, Antonios Negueruela, Ignacio Postnov, Konstantin Paizis, Adamantia Reig, Pablo Rodes-Roca, José Joaquín Tsygankov, Sergey Bird, Antony J. né Kühnel, Matthias Bissinger Blay, Pere Caballero, Isabel Coe, Malcolm J. Domingo, Albert Doroshenko, Victor Ducci, Lorenzo Falanga, Maurizio Grebenev, Sergei A. Grinberg, Victoria Hemphill, Paul Kreykenbohm, Ingo née Fritz, Sonja Kreykenbohm Li, Jian Lutovinov, Alexander A. Martínez-Núñez, Silvia Mas-Hesse, J. Miguel Masetti, Nicola McBride, Vanessa A. Neronov, Andrii Pottschmidt, Katja Rodriguez, Jérôme Romano, Patrizia Rothschild, Richard E. Santangelo, Andrea Sguera, Vito Staubert, Rüdiger Tomsick, John A. Torrejón, José Miguel Torres, Diego F. Walter, Roland Wilms, Jörn Wilson-Hodge, Colleen A. Zhang, Shu E-28692 Spain E-28692 Spain INAF - IASF Istituto di Astrofisica Spaziale e Fisica Cosmica Via A. Corti 12 MilanoI-20133 Italy Department of Astronomy ISDC University of Geneva Chemin d'Ecogia 16 VersoixCH-1290 Switzerland E-28692 Spain Department of Chemistry Physics and Astronomy Georgia College and State University MilledgevilleGA31061 United States AIM CEA CNRS Université Paris-Saclay Université de Paris Gif-sur-YvetteF-91191 France Université de Paris CNRS Astroparticule et Cosmologie ParisF-75006 France School of Physical Sciences and CfAR Dublin City University Dublin 9 Ireland Dublin Institute for Advanced Studies 31 Fitzwilliam Place Dublin 2 Ireland Department of Applied Physics & Astronomy University of Sharjah Sharjah United Arab Emirates Sharjah United Arab Emirates Department of Applied Physics University of Alicante AlicanteE-03080 Spain Sternberg Astronomical Institute Moscow State University Moscow119234 Russia Kazan Federal University Kazan Russia Institute of Astrophysics Foundation for Research and Technology-Hellas Heraklion Crete71110 Greece University of Crete Physics Department Institute of Theoretical & Computational Physics Heraklion Crete70013 Greece Department of Physics Systems Engineering and Signal Theory University of Alicante AlicanteE-03690 Spain University Institute of Physics Applied to Sciences and Technologies University of Alicante AlicanteE-03690 Spain Department of Physics and Astronomy University of Turku FI-20014 Finland Space Research Institute The Russian Academy of Sciences Profsoyuznaya Str. 84/32 Moscow117997 Russia School of Physics and Astronomy Faculty of Physical Sciences and Engineering University of Southampton SouthamptonSO17 1BJ United Kingdom Erwin-Rommel-Strae 1 Erlangen91058 Germany Universidad Internacional de Valencia - VIU C/Pintor Sorolla 21 Valencia46002 Spain E-28692 Spain Institut für Astronomie und Astrophysik Universität Tübingen Sand 1 Tübingen

High mass X-ray binaries are among the brightest X-ray sources in the Milky Way, as well as in nearby Galaxies. Thanks to their highly variable emissions and complex phenomenology, they have attracted the interest of the high energy astrophysical community since the dawn of X-ray Astronomy. In more recent years, they have challenged our comprehension of physical processes in many more energy bands, ranging from the infrared to very high energies. In this review, we provide a broad but concise summary of the physical processes dominating the emission from high mass X-ray binaries across virtually the whole electromagnetic spectrum. These comprise the interaction of stellar winds with the high gravitational and magnetic fields of compact objects, the behaviour of matter under extreme magnetic and gravity conditions, and the perturbation of the massive star evolutionary processes by presence in a binary system. We highlight the role of the INTEGRAL mission in the discovery of many of the most interesting objects in the high mass X-ray binary class and its contribution in reviving the interest for these sources over the past two decades. We show how the INTEGRAL discoveries have not only contributed to significantly increase the number of high mass X-ray binaries known, thus advancing our understanding of the population as a whole, but also have opened new windows of investigation that stimulated the multi-wavelength approach nowadays common in most astrophysical research fields. We conclude the review by providing an overview of future facilities being planned from the X-ray to the very high energy domain that will hopefully help us in finding an answer to the many questions left open after more than 18 years of INTEGRAL scientific observations. Copyright © 2020, The Authors. All rights reserved.

关键词： Galaxies

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The CALorimetric Electron Telescope (CALET) on the International Space Station: Results from the First Two Years On Orbit

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Journal of Physics: Conference Series 2019年第1期1181卷

作者： Y Asaoka O Adriani Y Akaike K Asano M G Bagliesi E Berti G Bigongiari W R Binns S Bonechi M Bongi A Bruno P Brogi J H Buckley N Cannady G Castellini C Checchia M L Cherry G Collazuol V Di Felice K Ebisawa H Fuke T G Guzik T Hams N Hasebe K Hibino M Ichimura K Ioka W Ishizaki M H Israel K Kasahara J Kataoka R Kataoka Y Katayose C Kato N Kawanaka Y Kawakubo K Kohri H S Krawczynski J F Krizmanic T Lomtadze P Maestro P S Marrocchesi A M Messineo J W Mitchell S Miyake A A Moiseev K Mori M Mori N Mori H M Motz K Munakata H Murakami S Nakahira J Nishimura G A De Nolfo S Okuno J F Ormes S Ozawa L Pacini F Palma V Pal'shin P Papini A V Penacchioni B F Rauch S B Ricciarini K Sakai T Sakamoto M Sasaki Y Shimizu A Shiomi R Sparvoli P Spillantini F Stolzi S Sugita J E Suh A Sulaj I Takahashi M Takayanagi M Takita T Tamura N Tateyama T Terasawa H Tomida S Torii Y Tsunesada Y Uchihori S Ueno E Vannuccini J P Wefel K Yamaoka S Yanagita A Yoshida K Yoshida Waseda Research Institute for Science and Engineering Waseda University Japan JEM Utilization Center Human Spaceflight Technology Directorate Japan Aerospace Exploration Agency Japan Department of Physics University of Florence Italy INFN Sezione di Florence Italy Department of Physics University of Maryland USA Astroparticle Physics Laboratory NASA/GSFC USA Institute for Cosmic Ray Research The University of Tokyo Japan Department of Physical Sciences Earth and Environment University of Siena Italy INFN Sezione di Pisa Italy Department of Physics Washington University USA Heliospheric Physics Laboratory NASA/GSFC USA Department of Physics and Astronomy Louisiana State University USA Institute of Applied Physics (IFAC) National Research Council (CNR) Italy Department of Physics and Astronomy University of Padova Italy INFN Sezione di Padova Italy University of Rome 'Tor Vergata' Italy INFN Sezione di Rome 'Tor Vergata' Italy Institute of Space and Astronautical Science Japan Aerospace Exploration Agency Japan CRESST and Astroparticle Physics Laboratory NASA/GSFC USA Kanagawa University Japan Faculty of Science and Technology Graduate School of Science and Technology Hirosaki University Japan Yukawa Institute for Theoretical Physics Kyoto University Japan National Institute of Polar Research Japan Faculty of Engineering Division of Intelligent Systems Engineering Yokohama National University Japan Faculty of Science Shinshu University Japan Hakubi Center Kyoto University Japan Department of Astronomy Graduate School of Science Kyoto University Japan College of Science and Engineering Department of Physics and Mathematics Aoyama Gakuin University Japan High Energy Accelerator Research Organization Japan University of Pisa Italy Department of Electrical and Electronic Systems Engineering National Institute of Technology Ibaraki College Japan Department of Astronomy University of Maryland College Park Maryland 20742 USA Department of Physical Sciences Co

The CALorimetric Electron Telescope (CALET) is a high-energy astroparticle physics space experiment installed on the International Space Station (ISS), developed and operated by Japan in collaboration with Italy and the united States. The CALET mission goals include the investigation of possible nearby sources of high-energy electrons, of the details of galactic particle acceleration and propagation, and of potential signatures of dark matter. CALET measures the cosmic-ray electron+positron flux up to 20 TeV, gamma-rays up to 10 TeV, and nuclei with Z=1 to 40 up to 1, 000 TeV for the more abundant elements during a long-term observation aboard the ISS. Starting science operation in mid-October 2015, CALET performed continuous observation without major interruption with close to 20 million triggered events over 10 GeV per month. Based on the data taken during the first two-years, we present an overview of CALET observations: 1) Electron+positron energy spectrum, 2) Nuclei analysis, 3) Gamma-ray observation including a characterization of on-orbit performance. Results of the electromagnetic counterpart search for LIGO/Virgo gravitational wave events are discussed as well.

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Author Correction: COVID-19 Disease Map, building a computational repository of SARS-CoV-2 virus-host interaction mechanisms

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Scientific data 2020年第1期7卷 247页

作者： Marek Ostaszewski Alexander Mazein Marc E Gillespie Inna Kuperstein Anna Niarakis Henning Hermjakob Alexander R Pico Egon L Willighagen Chris T Evelo Jan Hasenauer Falk Schreiber Andreas Dräger Emek Demir Olaf Wolkenhauer Laura I Furlong Emmanuel Barillot Joaquin Dopazo Aurelio Orta-Resendiz Francesco Messina Alfonso Valencia Akira Funahashi Hiroaki Kitano Charles Auffray Rudi Balling Reinhard Schneider Luxembourg Centre for Systems Biomedicine University of Luxembourg Belvaux Luxembourg. European Institute for Systems Biology and Medicine (EISBM) Vourles France. Ontario Institute for Cancer Research Toronto Canada. College of Pharmacy and Health Sciences St. John's University Queens NY USA. Institut Curie PSL Research University Mines Paris Tech Inserm Paris France. Department of Biology Univ. Évry University of Paris-Saclay Genopole 91025 Évry France. European Molecular Biology Laboratory European Bioinformatics Institute (EMBL-EBI) Hinxton UK. Institute of Data Science and Biotechnology Gladstone Institutes San Francisco United States. Department of Bioinformatics-BiGCaT NUTRIM Maastricht University Maastricht The Netherlands. Maastricht Centre for Systems Biology Maastricht University Maastricht The Netherlands. Helmholtz Zentrum München Institute of Computational Biology Neuherberg Germany. Center for Mathematics Technische Universität München Garching Germany. Faculty of Mathematics and Natural Sciences University of Bonn Bonn Germany. University of Konstanz Department of Computer and Information Science Konstanz Germany. Monash University Faculty of Information Technology Melbourne Australia. Computational Systems Biology of Infection and Antimicrobial-Resistant Pathogens Institute for Bioinformatics and Medical Informatics (IBMI) University of Tübingen 72076 Tübingen Germany. Department of Computer Science University of Tübingen 72076 Tübingen Germany. German Center for Infection Research (DZIF) partner site Tübingen Germany. Department of Molecular and Medical Genetics School of Medicine Oregon Health & Science University Portland USA. Department of Systems Biology & Bioinformatics University of Rostock Rostock Germany. Stellenbosch Institute of Advanced Study (STIAS) Wallenberg Research Centre at Stellenbosch University 7602 Stellenbosch South Africa. Research Programme on Biomedical informatics Hospital del Mar Medical Research

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

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Exome sequencing of Finnish isolates enhances rare-variant association power (vol 572, pg 323, 2019)

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NATURE 2019年第7783期575卷 E4-E4页

作者： Locke, Adam E. Steinberg, Karyn Meltz Chiang, Charleston W. K. Service, Susan K. Havulinna, Aki S. Stell, Laurel Pirinen, Matti Abel, Haley J. Chiang, Colby C. Fulton, Robert S. Jackson, Anne U. Kang, Chul Joo Kanchi, Krishna L. Koboldt, Daniel C. Larson, David E. Nelson, Joanne Nicholas, Thomas J. Pietila, Arto Ramensky, Vasily Ray, Debashree Scott, Laura J. Stringham, Heather M. Vangipurapu, Jagadish Welch, Ryan Yajnik, Pranav Yin, Xianyong Eriksson, Johan G. Ala-Korpela, Mika Jarvelin, Marjo-Riitta Mannikko, Minna Laivuori, Hannele Project, FinnGen Dutcher, Susan K. Stitziel, Nathan O. Wilson, Richard K. Hall, Ira M. Sabatti, Chiara Palotie, Aarno Salomaa, Veikko Laakso, Markku Ripatti, Samuli Boehnke, Michael Freimer, Nelson B. Department of Medicine Washington University School of Medicine St Louis USA McDonnell Genome Institute Washington University School of Medicine St Louis USA Department of Biostatistics and Center for Statistical Genetics University of Michigan School of Public Health Ann Arbor USA Department of Pediatrics Washington University School of Medicine St Louis USA Center for Neurobehavioral Genetics Jane and Terry Semel Institute for Neuroscience and Human Behavior University of California Los Angeles Los Angeles USA Center for Genetic Epidemiology Department of Preventive Medicine Keck School of Medicine University of Southern California Los Angeles USA Quantitative and Computational Biology Section Department of Biological Sciences University of Southern California Los Angeles USA Institute for Molecular Medicine Finland (FIMM) University of Helsinki Helsinki Finland National Institute for Health and Welfare Helsinki Finland Department of Biomedical Data Science Stanford University Stanford USA Department of Public Health University of Helsinki Helsinki Finland Helsinki Institute for Information Technology HIIT and Department of Mathematics and Statistics University of Helsinki Helsinki Finland Department of Genetics Washington University School of Medicine St Louis USA The Institute for Genomic Medicine Nationwide Children’s Hospital Columbus USA Department of Pediatrics The Ohio State University College of Medicine Columbus USA USTAR Center for Genetic Discovery and Department of Human Genetics University of Utah Salt Lake City USA Federal State Institution “National Medical Research Center for Preventive Medicine” of the Ministry of Healthcare of the Russian Federation Moscow Russia Departments of Epidemiology and Biostatistics Bloomberg School of Public Health Johns Hopkins University Baltimore USA Institute of Clinical Medicine Internal Medicine University of Eastern Finland Kuopio Finland Department of Public Health Solutions National Institute for

An Amendment to this paper has been published and can be accessed via a link at the top of the paper.

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Local nutrient addition drives plant diversity losses but not biotic homogenization in global grasslands

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Nature communications 2025年第1期16卷 4903页

作者： Qingqing Chen Shane A Blowes W Stanley Harpole Emma Ladouceur Elizabeth T Borer Andrew MacDougall Jason P Martina Jonathan D Bakker Pedro M Tognetti Eric W Seabloom Pedro Daleo Sally Power Christiane Roscher Peter B Adler Ian Donohue George Wheeler Carly Stevens G F Ciska Veen Anita C Risch Glenda M Wardle Yann Hautier Catalina Estrada Erika Hersch-Green Yujie Niu Pablo L Peri Anu Eskelinen Daniel S Gruner Harry Olde Venterink Carla D'Antonio Marc W Cadotte Sylvia Haider Nico Eisenhauer Jane Catford Risto Virtanen John W Morgan Michelle Tedder Sumanta Bagchi Maria C Caldeira Miguel N Bugalho Johannes M H Knops Chris R Dickman Nicole Hagenah Anke Jentsch Petr Macek Brooke B Osborne Lauri Laanisto Jonathan M Chase German Centre for Integrative Biodiversity Research (iDiv) Halle-Jena-Leipzig Puschstraße 4 04103 Leipzig Germany. chqq365@***. Senckenberg Museum for Natural History Görlitz D-02826 Görlitz Germany. chqq365@***. German Centre for Integrative Biodiversity Research (iDiv) Halle-Jena-Leipzig Puschstraße 4 04103 Leipzig Germany. Department of Computer Science Martin Luther University Halle-Wittenberg Halle (Saale) Germany. Helmholtz Center for Environmental Research-UFZ Department of Physiological Diversity Permoserstrasse 15 04318 Leipzig Germany. Martin Luther University Halle-Wittenberg Am Kirchtor 1 06108 Halle (Saale) Germany. Department of Biology University of Prince Edward Island Charlottetown PE Canada. Canadian Centre for Climate Change and Adaptation University of Prince Edward Island St. Peter's Bay Charlottetown PE C0A 2A0 Canada. School of Climate Change and Adaptation University of Prince Edward Island Charlottetown PE C1A 4P3 Canada. Department of Ecology Evolution and Behavior University of Minnesota St. Paul MN 55108 USA. Department of Integrative Biology University of Guelph Guelph ON N1G2W1 Canada. Department of Biology Texas State University San Marcos TX 78666 USA. School of Environmental and Forest Sciences University of Washington Seattle WA USA. Instituto de Investigaciones Fisiológicas y Ecológicas Vinculadas a La Agricultura (IFEVA) Facultad de Agronomía Universidad de Buenos Aires and CONICET Buenos Aires Argentina. Instituto de Investigaciones Marinas y Costeras (IIMyC) UNMdP-CONICET CC 1260 Correo Central B7600WAG Mar Del Plata Argentina. Hawkesbury Institute for the Environment Locked Bag 1797 Penrith NSW 2751 Australia. Department of Wildland Resources and the Ecology Center Utah State University Logan UT 84322 USA. Zoology School of Natural Sciences Trinity College Dublin Dublin Ireland. University of Nebraska-Lincoln Lincoln NE USA. Lancaster Environment Centre Lancaster University Lancaster LA1

Nutrient enrichment typically causes local plant diversity declines. A common but untested expectation is that nutrient enrichment also reduces variation in nutrient conditions among localities and selects for a smaller pool of species, causing greater diversity declines at larger than local scales and thus biotic homogenization. Here we apply a framework that links changes in species richness across scales to changes in the numbers of spatially restricted and widespread species for a standardized nutrient addition experiment across 72 grasslands on six continents. Overall, we find proportionally similar species loss at local and larger scales, suggesting similar declines of spatially restricted and widespread species, and no biotic homogenization after 4 years and up to 14 years of treatment. These patterns of diversity changes are generally consistent across species groups. Thus, nutrient enrichment poses threats to plant diversity, including for widespread species that are often critical for ecosystem functions.

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A second update on mapping the human genetic architecture of COVID-19

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Nature 2023年第7977期621卷 E7-E26页

作者： Masahiro Kanai Christine Stevens Benjamin M. Neale Mark Daly Andrea Ganna Amy Trankiem Mary K. Balaconis Samuli Ripatti Lindo Nkambul Mark J. Daly Sam Bryant Matthew Solomonson Shea J. Andrews Mattia Cordioli Juha Karjalainen Juha Mehtonen Matti Pirinen Andrea Corbetta Bradley Jermy Kati Donner Katja Kivinen Aarno Palotie Mari Kaunisto Kumar Veerapen Konrad J. Karczewski Alicia R. Martin Elizabeth G. Atkinson Kristin Tsuo Nikolas Baya Rahul Gupta Raymond K. Walters Duncan S. Palmer Gopal Sarma Nathan Cheng Wenhan Lu Claire Churchhouse Jacqueline I. Goldstein Daniel King Wei Zhou Cotton Seed Hilary Finucane F. Kyle Satterstrom Gita A. Pathak Akiko Iwasaki Karolina Chwialkowska Karolina Chwiałkowska Brooke N. Wolford Hajar Fauzan Ahmad Shea Andrews Kathrin Aprile von Hohenstaufen Puoti Palwende R. Boua Guillaume Butler-Laporte Celia M. T. Greenwood Bartha M. Knoppers Mark Lathrop Carmen L. Cadilla Francesca Colombo Nicole Dueker Chloe Kirk Atanu Kumar Dutta Yasser M. El-Sherbiny Jehan J. El-Jawhari Doaa Shahin Ahmed Elzeiny Tamer A. Mansour Madonna M. Eltoukhy Attia A. S. Mohamed Sahar Esmaeeli Annika Faucon Israel Fernández Cadenas Israel Fernandez-Cadenas Laia Llucià-Carol Natalia Cullell Elena Muiño Jara Cárcel-Márquez Margherita Francescatto Laurent Francioli Lindokuhle Nkambule Jatin Arora Soumya Raychaudhuri Caroline Cusick Lude Franke Macarena Fuentes Macarena Fuentes-Guajardo David Gómez Cabrero Emi N. Harry Philip Jansen József L. Szentpéteri Réka Várnai Elżbieta Kaja Athanasios Kousathanas Dorote Pasko Mark J. Caulfield Alex Stuckey Christopher A. Odhams Susan Walker Daniel Rhodes Richard H. Scott Loukas Moutsianas Afshan Siddiq Peter Goddard Sally Donovan Tala Zainy Fiona Maleady-Crowe Linda Todd Shahla Salehi Greg Elgar Georgia Chan Prabhu Arumugam Christine Patch Augusto Rendon Tom A. Fowler Jose E. Krieger Sanjay K. Patel Audrey Lemaçon Sophie Limou Pietro Lió Eirini Marouli Charles Hinds Minttu M. Marttila Carolina Medina-Gómez Isabelle Migeotte Soumyajit Mondal Andrés Moreno-Estrada Leire Moya Tomok Broad Institute of MIT and Harvard Cambridge MA USA Analytic and Translational Genetics Unit Massachusetts General Hospital Boston MA USA Program in Medical and Population Genetics Broad Institute of MIT and Harvard Cambridge MA USA Department of Biomedical Informatics Harvard Medical School Boston MA USA Program in Bioinformatics and Integrative Genomics Harvard Medical School Boston MA USA Institute for Molecular Medicine Finland (FIMM) University of Helsinki Helsinki Finland Institute for Molecular Medicine Finland University of Helsinki Helsinki Finland Institute for Molecular Medicine Finland (FIMM) HiLIFE University of Helsinki Helsinki Finland Public Health Faculty of Medicine University of Helsinki Helsinki Finland Analytic & Translational Genetics Unit Massachusetts General Hospital Boston MA USA Stanley Center for Psychiatric Research & Program in Medical and Population Genetics Cambridge UK Institute for Molecular Medicine Finland (FIMM) Univerisity of Helsinki Helsinki Finland University of California San Francisco San Francisco CA USA Department of Molecular and Human Genetics Baylor College of Medicine Houston TX USA Program in Biological and Biomedical Sciences Harvard Medical School Boston MA USA Department of Psychiatry School of Medicine Yale University New Haven CT USA Veteran Affairs Connecticut Healthcare System West Haven CT USA Yale University New Haven CT USA Centre for Bioinformatics and Data Analysis Medical University of Bialystok Bialystok Poland Department of Computational Medicine and Bioinformatics University of Michigan Ann Arbor MI USA Faculty of Industrial Sciences and Technology Universiti Malaysia Pahang Pahang Malaysia Icahn School of Medicine at Mount Sinai New York NY USA Genolier Innovation Network and Hub Swiss Medical Network Genolier Healthcare Campus Genolier Switzerland Immediate Independent Multidisciplinary Med & Biotech Research Association Milan Italy Clinical Research Unit of Nanor

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Octopus, a computational framework for exploring light-driven phenomena and quantum dynamics in extended and finite systems

arXiv

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arXiv 2019年

作者： Tancogne-Dejean, Nicolas Oliveira, Micael J.T. Andrade, Xavier Appel, Heiko Borca, Carlos H. Le Breton, Guillaume Buchholz, Florian Castro, Alberto Corni, Stefano Correa, Alfredo A. de Giovannini, Umberto Delgado, Alain Eich, Florian G. Flick, Johannes Gil, Gabriel Gomez, Adrián Helbig, Nicole Hübener, Hannes Jestädt, René Jornet-Somoza, Joaquim Larsen, Ask H. Lebedeva, Irina V. Lüders, Martin Marques, Miguel A.L. Ohlmann, Sebastian T. Pipolo, Silvio Rampp, Markus Rozzi, Carlo A. Strubbe, David A. Sato, Shunsuke A. Schäfer, Christian Theophilou, Iris Welden, Alicia Rubio, Angel Max Planck Institute for the Structure and Dynamics of Matter Luruper Chaussee 149 HamburgD-22761 Germany Quantum Simulations Group Lawrence Livermore National Laboratory LivermoreCA94551 United States Département de Physique École Normale Supérieure de Lyon 46 Allée d’Italie Lyon Cedex 07 France Institute for Biocomputation and Physics of Complex Systems University of Zaragoza Calle Mariano Esquillor Zaragoza50018 Spain ARAID Foundation Avda. de Ranillas 1-D Zaragoza50018 Spain Dipartimento di Scienze Chimiche Università degli studi di Padova via F. Marzolo 1 Padova35131 Italy CNR – Istituto Nanoscienze via Campi 213a Modena41125 Italy Xanadu 777 Bay Street TorontoONM5G 2C8 Canada John A. Paulson School of Engineering and Applied Sciences Harvard University CambridgeMA02138 United States Center for Computational Quantum Physics Flatiron Institute 162 5th Avenue New YorkNY10010 United States Instituto de Cibernética Matemática y Física Calle E 309 La Habana10400 Cuba Nanomat/Qmat/CESAM and ETSF Université de Liège Sart-TilmanB-4000 Belgium Nano-Bio Spectroscopy Group ETSF Universidad del País Vasco San Sebastián20018 Spain 06120 Germany Max Planck Computing and Data Facility Gießenbachstraße 2 Garching85741 Germany Universit de Lille CNRS Centrale Lille ENSCL Universit d Artois UMR 8181 UCCS Unit de Catalyse et Chimie du Solide LilleF-59000 France Department of Physics School of Natural Sciences University of California MercedCA95343 United States Center for Computational Sciences University of Tsukuba Tsukuba305-8577 Japan

Over the last years extraordinary advances in experimental and theoretical tools have allowed us to monitor and control matter at short time and atomic scales with a high-degree of precision. An appealing and challenging route towards engineering materials with tailored properties is to find ways to design or selectively manipulate materials, especially at the quantum level. To this end, having a state-of-the-art ab initio computer simulation tool that enables a reliable and accurate simulation of light-induced changes in the physical and chemical properties of complex systems is of utmost importance. The first principles real-space-based Octopus project was born with that idea in mind, providing an unique framework allowing to describe non-equilibrium phenomena in molecular complexes, low dimensional materials, and extended systems by accounting for electronic, ionic, and photon quantum mechanical effects within a generalized time-dependent density functional theory framework. The present article aims to present the new features that have been implemented over the last few years, including technical developments related to performance and massive parallelism. We also describe the major theoretical developments to address ultrafast light-driven processes, like the new theoretical framework of quantum electrodynamics density-functional formalism (QEDFT) for the description of novel light-matter hybrid states. Those advances, and other being released soon as part of the Octopus package, will enable the scientific community to simulate and characterize spatial and time-resolved spectroscopies, ultrafast phenomena in molecules and materials, and new emergent states of matter (QED-materials). Copyright © 2019, The Authors. All rights reserved.

关键词： Density functional theory

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Publisher Correction: Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes

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Nature genetics 2019年第7期51卷 1192-1193页

作者： Rainer Malik Ganesh Chauhan Matthew Traylor Muralidharan Sargurupremraj Yukinori Okada Aniket Mishra Loes Rutten-Jacobs Anne-Katrin Giese Sander W van der Laan Solveig Gretarsdottir Christopher D Anderson Michael Chong Hieab H H Adams Tetsuro Ago Peter Almgren Philippe Amouyel Hakan Ay Traci M Bartz Oscar R Benavente Steve Bevan Giorgio B Boncoraglio Robert D Brown Adam S Butterworth Caty Carrera Cara L Carty Daniel I Chasman Wei-Min Chen John W Cole Adolfo Correa Ioana Cotlarciuc Carlos Cruchaga John Danesh Paul I W de Bakker Anita L DeStefano Marcel den Hoed Qing Duan Stefan T Engelter Guido J Falcone Rebecca F Gottesman Raji P Grewal Vilmundur Gudnason Stefan Gustafsson Jeffrey Haessler Tamara B Harris Ahamad Hassan Aki S Havulinna Susan R Heckbert Elizabeth G Holliday George Howard Fang-Chi Hsu Hyacinth I Hyacinth M Arfan Ikram Erik Ingelsson Marguerite R Irvin Xueqiu Jian Jordi Jiménez-Conde Julie A Johnson J Wouter Jukema Masahiro Kanai Keith L Keene Brett M Kissela Dawn O Kleindorfer Charles Kooperberg Michiaki Kubo Leslie A Lange Carl D Langefeld Claudia Langenberg Lenore J Launer Jin-Moo Lee Robin Lemmens Didier Leys Cathryn M Lewis Wei-Yu Lin Arne G Lindgren Erik Lorentzen Patrik K Magnusson Jane Maguire Ani Manichaikul Patrick F McArdle James F Meschia Braxton D Mitchell Thomas H Mosley Michael A Nalls Toshiharu Ninomiya Martin J O'Donnell Bruce M Psaty Sara L Pulit Kristiina Rannikmäe Alexander P Reiner Kathryn M Rexrode Kenneth Rice Stephen S Rich Paul M Ridker Natalia S Rost Peter M Rothwell Jerome I Rotter Tatjana Rundek Ralph L Sacco Saori Sakaue Michele M Sale Veikko Salomaa Bishwa R Sapkota Reinhold Schmidt Carsten O Schmidt Ulf Schminke Pankaj Sharma Agnieszka Slowik Cathie L M Sudlow Christian Tanislav Turgut Tatlisumak Kent D Taylor Vincent N S Thijs Gudmar Thorleifsson Unnur Thorsteinsdottir Steffen Tiedt Stella Trompet Christophe Tzourio Cornelia M van Duijn Matthew Walters Nicholas J Wareham Sylvia Wassertheil-Smoller James G Wilson Kerri L Wiggins Qiong Yang Salim Yusuf Joshua C Bis Tomi Institute for Stroke and Dementia Research (ISD) University Hospital LMU Munich Munich Germany. Centre for Brain Research Indian Institute of Science Bangalore India. INSERM U1219 Bordeaux Population Health Research Center University of Bordeaux Bordeaux France. Stroke Research Group Division of Clinical Neurosciences University of Cambridge Cambridge UK. Department of Neurology Institute for Neurodegenerative Disease Bordeaux University Hospital Bordeaux France. Laboratory for Statistical Analysis RIKEN Center for Integrative Medical Sciences Yokohama Japan. Department of Statistical Genetics Osaka University Graduate School of Medicine Osaka Japan. Laboratory of Statistical Immunology Immunology Frontier Research Center (WPI-IFReC) Osaka University Suita Japan. Department of Neurology Massachusetts General Hospital (MGH) Harvard Medical School Boston MA USA. Laboratory of Experimental Cardiology Department of Cardiology Division of Heart and Lungs University Medical Center Utrecht University of Utrecht Utrecht the Netherlands. deCODE genetics/AMGEN Inc. Reykjavik Iceland. Center for Genomic Medicine MGH Boston MA USA. J. Philip Kistler Stroke Research Center Department of Neurology MGH Boston MA USA. Program in Medical and Population Genetics Broad Institute Cambridge MA USA. Population Health Research Institute McMaster University Hamilton Ontario Canada. Department of Epidemiology Erasmus University Medical Center Rotterdam the Netherlands. Department of Radiology and Nuclear Medicine Erasmus University Medical Center Rotterdam the Netherlands. Department of Medicine and Clinical Science Graduate School of Medical Sciences Kyushu University Fukuoka Japan. Department of Clinical Sciences Lund University Malmö Sweden. INSERM Institut Pasteur de Lille LabEx DISTALZ-UMR1167 Risk Factors and Molecular Determinants of Aging-Related Diseases Université Lille Lille France. Centre Hospitalier Université Lille Epidemiology and Public Health D

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

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