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Global Sensitivity Analysis for a perfusion bioreactor system in tissue engineering

IFAC-PapersOnLine 2021年第15期54卷 550-555页

作者： Ioana Nascu Tao Chen Wenli Du Key Laboratory of Advanced Control and Optimization for Chemical Processes Ministry of Education East China University of Science and Technology Shanghai 200237 China Shanghai Institute of Intelligent Science and Technology Tongji University Shanghai 200092 China Department of Chemical and Process Engineering University of Surrey GU2 7XH Guildford United Kingdom

This work presents a global sensitivity analysis and simulations of a perfusion bioreactor process using the method of high-dimensional model representation (HDMR). This method was developed to express the input–output relationships of a complex model with a high dimensional input space. The comprehensive mathematical model of convection and diffusion in a perfusion bioreactor, combined with cell growth kinetics, is developed and implemented using Computational Fluid Dynamics (with the commercial software COMSOL Multiphysics v5.5). The model describes the spatio-temporal evolution of glucose concentration, oxygen concentration, lactate concentration and cell density within a 3D polymeric scaffold. A quantitative analysis of the complex kinetic mechanisms using recent development of advanced mathematical approaches to global sensitivity and uncertainty analysis through HDMR can be exploited to investigate the important features of the perfusion bioreactor process as well as possible factors underlying qualitative discrepancies.

关键词： tissue engineering perfusion bioreactor CFD modeling high-dimensional model representation global sensitivity analysis

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A combined computational-fluid-dynamics model and control strategies for perfusion bioreactor systems in tissue engineering

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IFAC-PapersOnLine 2021年第3期54卷 324-329页

作者： Ioana Nascu Daniel Sebastia-Saez Tao Chen Wenli Du Key Laboratory of Advanced Control and Optimization for Chemical Processes Ministry of Education East China University of Science and Technology Shanghai 200237 China Shanghai Institute of Intelligent Science and Technology Tongji University Shanghai 200092 China Department of Chemical and Process Engineering University of Surrey GU2 7XH Guildford United Kingdom

This work sets the foundations for the design of control algorithms to facilitate manufacturing of a cell growth process using a continuous perfusion bioreactor. The algorithms are designed to work with different types of cell cultures and deal with major disturbances that might appear in the process. Different types of control strategies are designed, implemented and tested. First, a comprehensive mathematical model of convection and diffusion in a perfusion bioreactor, combined with cell growth kinetics, is developed and implemented using Computational Fluid Dynamics. The model describes the spatio-temporal evolution of glucose concentration and cell density within a 3D polymeric scaffold. Since such a model is too complex to be used directly for control studies, a simplified version is used for the design of the controllers. Finally, the performances of the control strategies are validated against the original high-fidelity CFD model, thus closing the loop. The simulations show good performances and satisfactory behavior.

关键词： tissue engineering perfusion bioreactor CFD modeling PID

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Implementation of adaptive fault-tolerant tracking control for robot manipulators with integral sliding mode

Research Square

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Research Square 2021年

作者： Liu, Linzhi Zhang, Liyin Hou, Yinlong Tang, Dafeng Liu, Hui Xi’an Key Laboratory of Advanced Control and Intelligent Process School of Automation Xi’an University of Posts and Telecommunications Xi’an China China Ship Scientific Research Center China China State Shipbuilding Corporation Limited Xi’an Dong Yi Science Technology and Industry Group Co. Ltd Xi’an China

This paper addresses an adaptive fault-tolerant tracking control for robot manipulators. By fully considering the effects of uncertainties and actuator effectiveness faults (UAEFs), a robust fault-tolerant tracking control combining with an auxiliary function and an integral sliding manifold is first developed for uncertain robot manipulators. Then, an adaptive law for unknown parameters of the upper bounded uncertainties is constructed to obtain a robust fault-tolerant approach with the elimination of the reaching phase of sliding mode control (SMC). The stability of the proposed approaches is accomplished by Lyapunov stable theory. The key contributions of the proposed approach are as follows: i) the reaching phase of SMC is removed in the control design and then the sliding mode starts at very beginning;(ii) the nominal control term is eliminated in the design of integral sliding surface and then the algebraic loop problem is also avoided in the proposed approach for robot manipulators;(iii) the simple control structure with an adaptive law is obtained for improving chattering-restraining ability of the proposed approach and then the effects of time delay and computational burden are also restrained from the proposed approach. Simulation and experimental comparisons have been accomplished for verifying the effectiveness of the proposed approach. © 2021, CC BY.

关键词： Sliding mode control

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The 110kV Live-Maintaining Robot control System Design for Substation Equipment in Complex Working Conditions

The 110kV Live-Maintaining Robot Control System Design for S...

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Chinese control Conference (CCC)

作者： Chenyu Hu Xin Chen Chengyu Li Guangxian Huang Cheng Zhou Xu Jian School of Automation China University of Geosciences Wuhan China Hubei Key Laboratory of Advanced Control and Intelligent Automation for Complex Systems Wuhan China School of Future Technology China University of Geosciences Wuhan China Distribution Department State Grid Hubei Electric Power Co. Ltd. Xianning Power Supply Company Xianning China Operations and Maintenance Department State Grid Hubei Electric Power Co. Ltd Xianning Xian'an District Power Supply Company Xianning China Equipment Technology Center State Grid Hubei Electric Power Co. Ltd. Electric Power Science Research Institute Wuhan China Engineering Research Center of Intelligent Technology for Geo-Exploration Ministry of Education Wuhan China

Live-maintaining work is essential for continuous power supply to the substation. To improve the safety and efficiency of live-maintaining work, this paper proposes an equipotential live-maintaining robot system suitable for 110kV voltage levels. Considering the narrow space, complex working conditions and strong electromagnetic interference in substations, binocular vision technology, manipulator trajectory planning algorithm based on time-energy optimization, high voltage electromagnetic shielding technology are utilized to develop the system, and the live-maintaining robot is successfully applied in actual substation. By accurately identifying and locating the joint bolts and insulator, the robot system can achieve equipotential live-disassemble, live-assemble the joint bolts within 18 minutes and live-clean insulator within 5 minutes, demonstrating its the effectiveness and practicability.

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Finite-time Sliding Mode control Under Dynamic Event-triggered Scheme ⁎

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IFAC-PapersOnLine 2020年第2期53卷 5069-5074页

作者： Jiarui Li Yugang Niu Bei Chen The Key Laboratory of Advanced Control and Optimization for Chemical Process (East China University of Science and Technology) Ministry of Education and The Shanghai Institute of Intelligent Science and Technology (Tongji University) Shanghai China The School of Electric and Electronic Engineering Shanghai University of Engineering Science Shanghai 201620 China

In this work, we investigate the finite-time boundedness (FTB) problem for a class of continuous-time uncertain systems via sliding mode control (SMC) method. A dynamic event-triggered scheme is introduced to determine whether the measurement output will be transmitted. And then, a state observer is designed by means of the transmitted output information, based on which a sliding surface in the estimation space is construct. It is shown that the corresponding SMC law can drive the system trajectories onto the specified sliding surface in a finite (possibly short) time. Meanwhile, a partitioning strategy is introduced to analyze the FTB over both reaching phase and the sliding motion, respectively. Finally, a numerical simulation is given.

关键词： Sliding mode control finite-time boundedness event-triggered control external disturbance partitioning strategy

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Output Feedback Based Iterative Learning control with Finite Frequency Range Specifications via a Heuristic Approach for Batch processes with Polytopic Uncertainties ⁎

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IFAC-PapersOnLine 2020年第2期53卷 1397-1402页

作者： Shoulin Hao Tao Liu Wojciech Paszke Hongfeng Tao Key Laboratory of Intelligent Control and Optimization for Industrial Equipment of Ministry of Education Dalian University of Technology Dalian 116024 China School of Control Science and Engineering Dalian University of Technology Dalian 116024 China Institute of Automation Electronic and Electrical Engineering University of Zielona Góra ul. Szafrana 2 65-516 Zielona Góra Poland Key Laboratory of Advanced Process Control for Light Industry of Ministry of Education Jiangnan University Wuxi 214122 China

For robust control and iterative optimization of industrial batch processes with polytopic uncertainties, this paper proposes a robust output feedback based iterative learning control (ILC) design in terms of finite frequency range stability specifications. Robust stability conditions for the closed-loop ILC system along both time and batch directions are first established based on the generalized Kalman-Yakubovich-Popov lemma and linear repetitive system theory. To facilitate the ILC controller design with respect to process uncertainties described in a polytopic form, extended sufficient conditions for the system stability are then derived in terms of matrix inequalities. Correspondingly, a two-stage heuristic approach is developed to iteratively compute feasible ILC controller gains for implementation. An illustrative example is given to demonstrate the effectiveness of the proposed control design.

关键词： Batch processes polytopic uncertainties output feedback iterative learning control finite frequency range design

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Regret and cumulative constraint violation analysis for online convex optimization with long term constraints

arXiv

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arXiv 2021年

作者： Yi, Xinlei Li, Xiuxian Yang, Tao Xie, Lihua Chai, Tianyou Johansson, Karl H. School of Electrical Engineering and Computer Science and Digital Futures KTH Royal Institute of Technology Stockholm Sweden Department of Control Science and Engineering College of Electronics and Information Engineering Shanghai Research Institute for Intelligent Autonomous Systems Institute for Advanced Study Tongji University Shanghai China State Key Laboratory of Synthetical Automation for Process Industries Northeastern University Shenyang China School of Electrical and Electronic Engineering Nanyang Technological University Singapore Singapore

This paper considers online convex optimization with long term constraints, where constraints can be violated in intermediate rounds, but need to be satisfied in the long run. The cumulative constraint violation is used as the metric to measure constraint violations, which excludes the situation that strictly feasible constraints can compensate the effects of violated constraints. A novel algorithm is first proposed and it achieves an O(Tmax{c,1-c}) bound for static regret and an O(T (1-c)/2) bound for cumulative constraint violation, where c ϵ (0, 1) is a user-defined trade-off parameter, and thus has improved performance compared with existing results. Both static regret and cumulative constraint violation bounds are reduced to O(log(T )) when the loss functions are strongly convex, which also improves existing results. In order to achieve the optimal regret with respect to any comparator sequence, another algorithm is then proposed and it achieves the optimal O( p T (1 + PT )) regret and an O(√T) cumulative constraint violation, where PT is the path-length of the comparator sequence. Finally, numerical simulations are provided to illustrate the effectiveness of the theoretical results. Copyright © 2021, The Authors. All rights reserved.

关键词： Comparators (optical)

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Point cloud-based registration and image fusion between cardiac SPECT MPI and CTA

arXiv

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arXiv 2024年

作者： Shaojie, Tang Penpen, Miao Xingyu, Gao Yu, Zhong Dantong, Zhu Haixing, Wen Zhihui, Xu Qiuyue, Wei Hongping, Yao Xin, Huang Rui, Gao Chen, Zhao Weihua, Zhou School of Automation Xi’an University of Posts and Telecommunications Shaanxi Xi’an710121 China Xi'an Key Laboratory of Advanced Control and Intelligent Process Shaanxi Xi’an710121 China Second Clinical Medical School of Nanjing Medical University Jiangsu Nanjing210011 China Department of Cardiology The First Affiliated Hospital of Nanjing Medical University Jiangsu Nanjing210000 China Department of Pharmacy The First Affiliated Hospital of Xi’an Jiaotong University Shaanxi Xi’an710061 China Department of Cardiology The First Affiliated Hospital of Xi’an Jiaotong University Shaanxi Xi’an710061 China Department of Nuclear Medicine The First Affiliated Hospital of Xi’an Jiaotong University Shaanxi Xi’an710061 China Department of Computer Science Kennesaw State University MariettaGA30060 United States Department of Applied Computing Center for Biocomputing and Digital Health Institute of Computing and Cybersystems Health Research Institute Michigan Technological University HoughtonMI49931 United States

A method was proposed for the point cloud-based registration and image fusion between cardiac single photon emission computed tomography (SPECT) myocardial perfusion images (MPI) and cardiac computed tomography angiograms (CTA). Firstly, the left ventricle (LV) epicardial regions (LVERs) in SPECT and CTA images were segmented by using different U-Net neural networks trained to generate the point clouds of the LV epicardial contours (LVECs). Secondly, according to the characteristics of cardiac anatomy, the special points of anterior and posterior interventricular grooves (APIGs) were manually marked in both SPECT and CTA image volumes. Thirdly, we developed an in-house program for coarsely registering the special points of APIGs to ensure a correct cardiac orientation alignment between SPECT and CTA images. Fourthly, we employed ICP, SICP or CPD algorithm to achieve a fine registration for the point clouds (together with the special points of APIGs) of the LV epicardial surfaces (LVERs) in SPECT and CTA images. Finally, the image fusion between SPECT and CTA was realized after the fine registration. The experimental results showed that the cardiac orientation was aligned well and the mean distance error of the optimal registration method (CPD with affine transform) was consistently less than 3 mm. The proposed method could effectively fuse the structures from cardiac CTA and SPECT functional images, and demonstrated a potential in assisting in accurate diagnosis of cardiac diseases by combining complementary advantages of the two imaging modalities. © 2024, CC BY.

关键词： Image fusion

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Facial expression recognition based on deep residual network

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Journal of Computers (Taiwan) 2020年第2期31卷 12-19页

作者： Qu, Junsuo Zhang, Ruijun Zhang, Zhiwei Pan, Jeng-Shyang Xi'an Key Laboratory of Advanced Control and Intelligent Process School of Automation Xi'an University of Posts and Telecommunications Xi'an710061 China Innovation Lab Xi'an University of Posts and Telecommunications Xi'an710061 China School of Information Science and Engineering Fujian University of Technolgy Fuzhou350000 China

Low accuracy of facial expression recognition for traditional methods, a facial expression recognition algorithm is proposed. Using the deep residual network model as the feature extractor, the residual block of the residual network is improved to enhance the information flow in the deep network. During training, apply some pre-processing techniques to extract only expression specific features from a face image and explore the presentation order of the samples and use softmax to classify and identify the extracted feature vectors. The experimental results show that a higher recognition rate is obtained on FER-2013. © 2020 Computer Society of the Republic of China. All rights reserved.

关键词： Face recognition

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Preface——Special Issue on New Directions in Nonlinear and Distributed control

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Journal of Systems Science & Complexity 2018年第1期31卷 1-3页

作者： LIU Tengfei XIN Bin JIANG Zhong-Ping State Key Laboratory of Synthetical Automation for Process Industries Northeastern University Shenyang 110819 China School of Automation State Key Laboratory of Intelligent Control and Decision of Complex Systems Beijing Advanced Innovation Center for Intelligent Robots and Systems Beijing Institute of Technology Beijing 100081 China Tandon School of Engineering New York University Brooklyn NY 11201 USA

Nonlinearity is ubiquitous in engineering and natural *** development of nonlinear control can be traced back to decades *** date,the research has reached the stage that emphasizes developing methodologies that can ha... 详细信息

关键词：控制问题非线性分布式工程应用程序电子物理自然系统生产线相互作用

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