In this work, a model predictive control of a fed-batch bioreactor is presented, described by the dynamic enzyme-cost FBA model (deFBA). The deFBA model is employed within a bilevel optimization to obtain fed-batch op...
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Modulating the expression of target genes is an effective metabolic engineering approach to increase bioprocess productivity. In this work, a bilevel optimization framework is applied for dynamic manipulation of gene ...
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We develop a stability preserving model reduction method for linearly coupled linear time-invariant (LTI) systems. The method extends the work of Monshizadeh et al. for multi-agent systems with identical LTI agents. T...
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We develop a stability preserving model reduction method for linearly coupled linear time-invariant (LTI) systems. The method extends the work of Monshizadeh et al. for multi-agent systems with identical LTI agen...
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