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Relationship between pulmonary nodule malignancy and surrounding pleurae, airways and vessels: a quantitative study using the public LIDC-IDRI dataset

arXiv

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arXiv 2021年

作者： Qin, Yulei Gu, Yun Zhang, Hanxiao Yang, Jie Wang, Lihui Wang, Zhexin Yao, Feng Zhu, Yue-Min Institute of Image Processing and Pattern Recognition Shanghai Jiao Tong University Shanghai200240 China Institute of Medical Robotics Shanghai Jiao Tong University Shanghai200240 China CREATIS INSA Lyon CNRS UMR 5220 INSERM U1206 Université de Lyon Villeurbanne69621 France Key Laboratory of Intelligent Medical Image Analysis and Precise Diagnosis of Guizhou Province School of Computer Science and Technology Guizhou University Guiyang550025 China Department of Thoracic Surgery Shanghai Chest Hospital Shanghai Jiao Tong University Shanghai200025 China

Objectives: To investigate whether the pleurae, airways and vessels surrounding a nodule on non-contrast computed tomography (CT) can discriminate benign and malignant pulmonary nodules. Materials and Methods: The LIDC-IDRI dataset, one of the largest publicly available CT database, was exploited for study. A total of 1556 nodules from 694 patients were involved in statistical analysis, where nodules with average scorings 3 were respectively denoted as benign and malignant. Besides, 339 nodules from 113 patients with diagnosis ground-truth were independently evaluated. Computer algorithms were developed to segment pulmonary structures and quantify the distances to pleural surface, airways and vessels, as well as the counting number and normalized volume of airways and vessels near a nodule. Odds ratio (OR) and Chi-square (χ2) testing were performed to assess the correlation between features of surrounding structures and nodule malignancy. A non-parametric receiver operating characteristic (ROC) analysis was conducted in logistic regression to evaluate discrimination ability of each structure. Results: For the benign and malignant groups, the average distances from nodules to pleural surface, airways and vessels are respectively (6.56, 5.19), (37.08, 26.43) and (1.42, 1.07) mm. The correlation between nodules and the counting number of airways and vessels that contact or project towards nodules are respectively (OR=22.96, χ2=105.04) and (OR=7.06, χ2=290.11). The correlation between nodules and the volume of airways and vessels are (OR=9.19, χ2=159.02) and (OR=2.29, χ2=55.89). The areas-under-curves (AUCs) for pleurae, airways and vessels are respectively 0.5202, 0.6943 and 0.6529. Conclusion: Our results show that malignant nodules are often surrounded by more pulmonary structures compared with benign ones, suggesting that features of these structures could be viewed as lung cancer biomarkers. © 2021, CC BY.

关键词： Computerized tomography

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Size-Invariance Matters: Rethinking Metrics and Losses for Imbalanced Multi-object Salient Object Detection

arXiv

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arXiv 2024年

作者： Li, Feiran Xu, Qianqian Bao, Shilong Yang, Zhiyong Cong, Runmin Cao, Xiaochun Huang, Qingming Institute of Information Engineering Chinese Academy of Sciences Beijing China School of Cyber Security University of Chinese Academy of Sciences Beijing China Key Laboratory of Intelligent Information Processing Institute of Computing Technology Chinese Academy of Sciences Beijing China School of Computer Science and Technology University of Chinese Academy of Sciences Beijing China Institute of Information Science Beijing Jiaotong University Beijing China School of Control Science and Engineering Shandong University Jinan China Key Laboratory of Machine Intelligence and System Control Ministry of Education Jinan China School of Cyber Science and Tech. Sun Yat-Sen University Shenzhen Campus China Key Laboratory of Big Data Mining and Knowledge Management Chinese Academy of Sciences Beijing China

This paper explores the size-invariance of evaluation metrics in Salient Object Detection (SOD), especially when multiple targets of diverse sizes co-exist in the same image. We observe that current metrics are size-sensitive, where larger objects are focused, and smaller ones tend to be ignored. We argue that the evaluation should be size-invariant because bias based on size is unjustified without additional semantic information. In pursuit of this, we propose a generic approach that evaluates each salient object separately and then combines the results, effectively alleviating the imbalance. We further develop an optimization framework tailored to this goal, achieving considerable improvements in detecting objects of different sizes. Theoretically, we provide evidence supporting the validity of our new metrics and present the generalization analysis of SOD. Extensive experiments demonstrate the effectiveness of our method. The code is available at https://***/Ferry-Li/SI-SOD. Copyright © 2024, The Authors. All rights reserved.

关键词： Object detection

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Learning tubule-sensitive CNNs for pulmonary airway and artery-vein segmentation in CT

arXiv

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arXiv 2020年

作者： Qin, Yulei Zheng, Hao Gu, Yun Huang, Xiaolin Yang, Jie Wang, Lihui Yao, Feng Zhu, Yue-Min Yang, Guang-Zhong Institute of Image Processing and Pattern Recognition Institute of Medical Robotics Shanghai Jiao Tong University Shanghai China Key Laboratory of Intelligent Medical Image Analysis and Precise Diagnosis of Guizhou Province School of Computer Science and Technology Guizhou University Guiyang China Department of Thoracic Surgery Shanghai Chest Hospital Shanghai Jiao Tong University Shanghai China Université de Lyon INSA Lyon CREATIS CNRS INSERM UMR 5220 VilleurbanneU1206 France Institute of Medical Robotics School of Biomedical Engineering Shanghai Jiao Tong University Shanghai China

Training convolutional neural networks (CNNs) for segmentation of pulmonary airway, artery, and vein is challenging due to sparse supervisory signals caused by the severe class imbalance between tubular targets and background. We present a CNNs-based method for accurate airway and artery-vein segmentation in non-contrast computed tomography. It enjoys superior sensitivity to tenuous peripheral bronchioles, arterioles, and venules. The method first uses a feature recalibration module to make the best use of features learned from the neural networks. Spatial information of features is properly integrated to retain relative priority of activated regions, which benefits the subsequent channel-wise recalibration. Then, attention distillation module is introduced to reinforce representation learning of tubular objects. Fine-grained details in high-resolution attention maps are passing down from one layer to its previous layer recursively to enrich context. Anatomy prior of lung context map and distance transform map is designed and incorporated for better artery-vein differentiation capacity. Extensive experiments demonstrated considerable performance gains brought by these components. Compared with state-of-the-art methods, our method extracted much more branches while maintaining competitive overall segmentation performance. Codes and models are available at http://***/News/56. © 2020, CC BY.

关键词： Computerized tomography

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Tigc-Net: Transformer-Improved Graph Convolution Network for Spatio-Temporal Prediction

SSRN

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SSRN 2022年

作者： Chen, Kai Yang, Chunfeng Zhou, Zhengyuan Liu, Yao Ji, Tianjiao Sun, Weiya Chen, Yang School of Cyber Science and Engineering Southeast University Nanjing210096 China Key Laboratory of Computer Network and Information Integration Southeast University Ministry of Education Nanjing210096 China The College of Software Engineering Southeast University Nanjing210096 China Laboratory of Image Science and Technology The School of Computer Science and Engineering Southeast University Nanjing210096 China Jiangsu Key Laboratory of Molecular and Functional Imaging Department of Radiology Zhongda Hospital Southeast University Nanjing210009 China Jiangsu Provincial Joint International Research Laboratory of Medical Information Processing School of Computer Science and Engineering Southeast University Nanjing210096 China NHC Key Laboratory of Medical Virology and Viral Diseases National Institute for Viral Disease Control and Prevention Chinese Center for Disease Control and Prevention Beijing China Beijing Institute of Tracking and Communication Technology Beijing100094 China

Modeling spatio-temporal sequences is an important topic yet challenging for existing neural networks. Most of the current spatio-temporal sequence prediction methods usually capture features separately in temporal and spatial dimensions or employ multiple mutually independent local spatio-temporal graphs to represent a spatio-temporal sequence. The first kind of method mentioned above is difficult to mine the complex spatio-temporal correlations, while the other is limited for the accuracy of long-term predictions. To handle these issues, this paper proposes a Transformer-Improved Graph Convolution Network for spatio-temporal prediction. Specifically, the temporal location encoding method is exploited to derive the spatio-temporal characteristics of the sequence utilizing a spatio-temporal feature fusion network. In addition, a spatio-temporal attention network is developed to enhance the spatio-temporal correlation of the sequence, and the dynamic spatial features of sequence are further extracted through the adaptive graph convolution network. A private dataset and a public dataset are employed to demonstrate the performance of the proposed TIGC-Net. The qualitative and quantitative results show that the proposed TIGC-Net can extract dynamic spatiotemporal properties more effectively, enhance the spatio-temporal correlation of sequences and improve the prediction accuracy compared with four stateof-the-art. © 2022, The Authors. All rights reserved.

关键词： Convolution

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A review of big data technology and its application in cancer care

引用

Computers in Biology and Medicine 2024年 176卷 108577-108577页

作者： Xiao, Tianyun Kong, Shanshan Zhang, Zichen Hua, Dianbo Liu, Fengchun Hebei Key Laboratory of Data Science and Application North China University of Science and Technology Hebei Tangshan063210 China The Key Laboratory of Engineering Computing in Tangshan City North China University of Science and Technology Hebei Tangshan063210 China College of Science North China University of Science and Technology Hebei Tangshan063210 China Hebei Engineering Research Center for the Intelligentization of Iron Ore Optimization and Ironmaking Raw Materials Preparation Processes North China University of Science and Technology Hebei Tangshan China Tangshan Intelligent Industry and Image Processing Technology Innovation Center North China University of Science and Technology Hebei Tangshan China Beijing Sitairui Cancer Data Analysis Joint Laboratory Beijing101149 China

The development of modern medical devices and information technology has led to a rapid growth in the amount of data available for health protection information, with the concept of medical big data emerging globally, along with significant advances in cancer care relying on data-driven approaches. However, outstanding issues such as fragmented data governance, low-quality data specification, and data lock-in still make sharing challenging. Big data technology provides solutions for managing massive heterogeneous data while combining artificial intelligence (AI) techniques such as machine learning (ML) and deep learning (DL) to better mine the intrinsic connections between data. This paper surveys and organizes recent articles on big data technology and its applications in cancer, dividing them into three different types to outline their primary content and summarize their critical role in assisting cancer care. It then examines the latest research directions in big data technology in cancer and evaluates the current state of development of each type of application. Finally, current challenges and opportunities are discussed, and recommendations are made for the further integration of big data technology into the medical industry in the future. © 2024 Elsevier Ltd

关键词： Big data

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A Learning Convolutional Neural Network Approach for Network Robustness Prediction

arXiv

引用

arXiv 2022年

作者： Lou, Yang Wu, Ruizi Li, Junli Wang, Lin Li, Xiang Chen, Guanrong The Department of Computing and Decision Sciences Lingnan University Hong Kong The Key Laboratory of System Control and Information Processing Ministry of Education of China Shanghai200240 China The College of Computer Science Sichuan Normal University Chengdu610066 China The Department of Automation Shanghai Jiao Tong University Shanghai200240 China The Institute of Complex Networks and Intelligent Systems Shanghai Research Institute for Intelligent Autonomous Systems Tongji University Shanghai201210 China The Department of Control Science and Engineering Tongji University Shanghai200240 China The Department of Electrical Engineering City University of Hong Kong Hong Kong

Network robustness is critical for various societal and industrial networks again malicious attacks. In particular, connectivity robustness and controllability robustness reflect how well a networked system can maintain its connectedness and controllability against destructive attacks, which can be quantified by a sequence of values that record the remaining connectivity and controllability of the network after a sequence of node- or edge-removal attacks. Traditionally, robustness is determined by attack simulations, which are computationally very time-consuming or even practically infeasible. In this paper, an improved method for network robustness prediction is developed based on learning feature representation using convolutional neural network (LFR-CNN). In this scheme, higher-dimensional network data are compressed to lower-dimensional representations, and then passed to a CNN to perform robustness prediction. Extensive experimental studies on both synthetic and real-world networks, both directed and undirected, demonstrate that 1) the proposed LFR-CNN performs better than other two state-of-the-art prediction methods, with significantly lower prediction errors;2) LFR-CNN is insensitive to the variation of the network size, which significantly extends its applicability;3) although LFR-CNN needs more time to perform feature learning, it can achieve accurate prediction faster than attack simulations;4) LFR-CNN not only can accurately predict network robustness, but also provides a good indicator for connectivity robustness, better than the classical spectral measures. © 2022, CC BY.

关键词： Complex networks

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SPP-CNN: An Efficient Framework for Network Robustness Prediction

arXiv

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arXiv 2023年

作者： Wu, Chengpei Lou, Yang Wang, Lin Li, Junli Li, Xiang Chen, Guanrong The College of Computer Science Sichuan Normal University Chengdu610066 China The Key Laboratory of System Control and Information Processing Ministry of Education Shanghai200240 China The Department of Computer Science National Yang Ming Chiao Tung University Hsinchu300 Taiwan The Department of Automation Shanghai Jiao Tong University Shanghai200240 China The Institute of Complex Networks and Intelligent Systems Shanghai Research Institute for Intelligent Autonomous Systems Tongji University Shanghai201210 China The Department of Control Science and Engineering Tongji University Shanghai200240 China The Department of Electrical Engineering City University of Hong Kong Hong Kong

This paper addresses the robustness of a network to sustain its connectivity and controllability against malicious attacks. This kind of network robustness is typically measured by the time-consuming attack simulation, which returns a sequence of values that record the remaining connectivity and controllability after a sequence of node- or edge-removal attacks. For improvement, this paper develops an efficient framework for network robustness prediction, the spatial pyramid pooling convolutional neural network (SPP-CNN). The new framework installs a spatial pyramid pooling layer between the convolutional and fully-connected layers, overcoming the common mismatch issue in the CNN-based prediction approaches and extending its generalizability. Extensive experiments are carried out by comparing SPP-CNN with three state-of-the-art robustness predictors, namely a CNN-based and two graph neural networks-based frameworks. Synthetic and real-world networks, both directed and undirected, are investigated. Experimental results demonstrate that the proposed SPP-CNN achieves better prediction performances and better generalizability to unknown datasets, with significantly lower time-consumption, than its counterparts. © 2023, CC BY.

关键词： Complex networks

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PUGAN: Physical Model-Guided Underwater image Enhancement Using GAN with Dual-Discriminators

arXiv

引用

arXiv 2023年

作者： Cong, Runmin Yang, Wenyu Zhang, Wei Li, Chongyi Guo, Chun-Le Huang, Qingming Kwong, Sam Institute of Information Science Beijing Jiaotong University Beijing100044 China School of Control Science and Engineering Shandong University Jinan250061 China Key Laboratory of Machine Intelligence and System Control Ministry of Education Jinan250061 China Beijing Key Laboratory of Advanced Information Science and Network Technology Beijing100044 China College of Computer Science Nankai University Tianjin300350 China School of Computer Science and Technology University of Chinese Academy of Sciences Beijing101408 China Key Laboratory of Intelligent Information Processing Institute of Computing Technology Chinese Academy of Sciences Beijing100190 China Peng Cheng Laboratory Shenzhen518055 China Department of Computer Science City University of Hong Kong Hong Kong City University of Hong Kong Shenzhen Research Institute Shenzhen51800 China

Due to the light absorption and scattering induced by the water medium, underwater images usually suffer from some degradation problems, such as low contrast, color distortion, and blurring details, which aggravate the difficulty of downstream underwater understanding tasks. Therefore, how to obtain clear and visually pleasant images has become a common concern of people, and the task of underwater image enhancement (UIE) has also emerged as the times require. Among existing UIE methods, Generative Adversarial Networks (GANs) based methods perform well in visual aesthetics, while the physical model-based methods have better scene adaptability. Inheriting the advantages of the above two types of models, we propose a physical model-guided GAN model for UIE in this paper, referred to as PUGAN. The entire network is under the GAN architecture. On the one hand, we design a Parameters Estimation subnetwork (Par-subnet) to learn the parameters for physical model inversion, and use the generated color enhancement image as auxiliary information for the Two-Stream Interaction Enhancement subnetwork (TSIE-subnet). Meanwhile, we design a Degradation Quantization (DQ) module in TSIE-subnet to quantize scene degradation, thereby achieving reinforcing enhancement of key regions. On the other hand, we design the Dual-Discriminators for the style-content adversarial constraint, promoting the authenticity and visual aesthetics of the results. Extensive experiments on three benchmark datasets demonstrate that our PUGAN outperforms state-of-the-art methods in both qualitative and quantitative metrics. The code and results can be found from the link of https://***/proj_***. © 2023, CC BY-NC-SA.

关键词： Discriminators

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A method for detecting floating objects on water based on edge computing

A method for detecting floating objects on water based on ed...

引用

IEEE International Symposium on Broadband Multimedia Systems and Broadcasting (BMSB)

作者： He Li Shuaipeng Yang Jinjiang Liu Honglin Fang Zhumu Fu Rui Zhang Huimei Jia Lianmeng Lv Henan Costar Group Co. Ltd Nanyang Henan China College of Information Engineering Henan University of Science and Technology Luoyang Henan China Henan Engineering Research Center of Intelligent Processing for Big Data of Digital Image School of Computer Science and Technology Nanyang Normal University Nanyang China State Key Laboratory of Networking and Switching Technology Beijing University of Posts and Telecommunication Beijing China Xi'an Hengpin Electronic Technology Co. Ltd Xi’an China

With the development and application of computer vision, many target detection networks are applied to the detection of floating objects in rivers. For the detection problems such as small targets easily missed and misdetected in water surface floating object detection tasks and difficult to deploy models. An edge computing-oriented approach to river floater detection is proposed. First, a four-fold down-sampling feature layer is added to the YOLOv5 network which enhances more target detail features and improves the detection capability of small objects. Second, CA (Coordinate Attention) is added to the Backbone to suppress background noise interference, and different pooling is used to accommodate different hierarchical features. Then, a bilinear interpolation method is adopted for up-sampling to avoid the loss of small object features. Design a data enhancement algorithm for small targets based on Mosaic to increase the number of small objects and enrich the training background. Finally, for the edge computing architecture platform, the channel pruning algorithm is used to prune and compress the model structure to adapt to the computing capability of edge devices. The experimental results show that the method can effectively improve the detection capability of the network for floating objects on the water surface. The detection accuracy can reach 93.6%, and the detection speed can be maintained at 36 frames per second, which can achieve high-precision real-time detection of floating objects on the water surface.

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Fast and accurate single-image depth estimation on mobile devices, mobile AI 2021 challenge: Report

arXiv

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arXiv 2021年

作者： Ignatov, Andrey Malivenko, Grigory Plowman, David Shukla, Samarth Timofte, Radu Zhang, Ziyu Wang, Yicheng Huang, Zilong Luo, Guozhong Yu, Gang Fu, Bin Wang, Yiran Li, Xingyi Shi, Min Xian, Ke Cao, Zhiguo Du, Jin-Hua Wu, Pei-Lin Ge, Chao Yao, Jiaoyang Tu, Fangwen Li, Bo Yoo, Jung Eun Seo, Kwanggyoon Xu, Jialei Li, Zhenyu Liu, Xianming Jiang, Junjun Chen, Wei-Chi Joya, Shayan Fan, Huanhuan Kang, Zhaobing Li, Ang Feng, Tianpeng Liu, Yang Sheng, Chuannan Yin, Jian Benavides, Fausto T. Computer Vision Lab ETH Zurich Switzerland Ltd AI Witchlabs Switzerland Tencent GY-Lab China Key Laboratory of Image Processing and Intelligent Control Ministry of Education School of Artificial Intelligence and Automation Huazhong University of Science and Technology China Nanjing Artificial Intelligence Chip Research Institute of Automation Chinese Academy of Sciences China Black Sesame Technologies Inc. Singapore Singapore Visual Media Lab KAIST Korea Republic of Harbin Institute of Technology China Peng Cheng Laboratory China Multimedia and Computer Vision Laboratory National Cheng Kung University Taiwan Samsung Research UK United Kingdom OPPO Research Institute China ETH Zurich Switzerland

Depth estimation is an important computer vision problem with many practical applications to mobile devices. While many solutions have been proposed for this task, they are usually very computationally expensive and thus are not applicable for on-device inference. To address this problem, we introduce the first Mobile AI challenge, where the target is to develop an end-to-end deep learning-based depth estimation solutions that can demonstrate a nearly real-time performance on smartphones and IoT platforms. For this, the participants were provided with a new large-scale dataset containing RGB-depth image pairs obtained with a dedicated stereo ZED camera producing high-resolution depth maps for objects located at up to 50 meters. The runtime of all models was evaluated on the popular Raspberry Pi 4 platform with a mobile ARM-based Broadcom chipset. The proposed solutions can generate VGA resolution depth maps at up to 10 FPS on the Raspberry Pi 4 while achieving high fidelity results, and are compatible with any Android or Linux-based mobile devices. A detailed description of all models developed in the challenge is provided in this paper. Copyright © 2021, The Authors. All rights reserved.

关键词： Computer operating systems

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