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Manifestations of 9754 gout patients in a Chinese clinical center: A 10-year observational study

Revue du Rhumatisme (Edition Francaise) 2022年第1期89卷 65-71页

作者： Gao, Qianhui Cheng, Xiaoyu Merriman, Tony R. Wang, Can Cui, Lingling Zhang, Hui Sun, Wenyan Wang, Jing Wang, Feiyue Li, Changgui Lu, Jie Shandong Provincial Key Laboratory of Metabolic Diseases and Qingdao Key Laboratory of Gout Department of Endocrinology and Metabolism the Affiliated Hospital of Qingdao University Qingdao 266003 China Institute of Metabolic Diseases Qingdao University Qingdao 266003 China Department of Biochemistry University of Otago Dunedin New Zealand Division of Clinical Immunology and Rheumatology University of Alabama Birmingham Alabama United States Institute of Smart Healthcare Systems Qingdao Academy of Intelligent Industries Qingdao 266109 China The State Key Laboratory for Management and Control for Complex Systems Institute of Automation Chinese Academy of Sciences Beijing 100190 China

Objectif: La prévalence de la goutte augmente, mais les études analysant ses caractéristiques cliniques dans de grands échantillons sont insuffisantes. Cette étude s'attache à clarifier les changements dans les manifestations cliniques de la goutte en Chine au cours des dix dernières années et à analyser les caractéristiques cliniques et les facteurs de risque de la goutte précoce. Méthodes: Les manifestations cliniques de la goutte ont été comparées chez 9754 patients reçus pour la première fois dans notre établissement entre 2008 et 2012 (premier groupe) ou entre 2013 et 2018 (dernier groupe). La goutte apparue ≤ 30 ans a été définie comme goutte précoce et > 30 ans, comme goutte tardive. Les caractéristiques cliniques et les facteurs de risque ont été comparés entre les groupes. Résultats: La goutte est apparue 4,14 ans plus tôt dans le dernier groupe (2013-2018, 5979 patients) et le pourcentage de goutte précoce (3827 patients) y était plus élevé. La durée de la maladie était significativement plus courte (5,72 ± 0,09 contre 6,01 ± 0,11, p < 0,05) et la proportion de patients présentant des tophi était plus faible dans le dernier groupe (20,0% contre 22,0%, p<0,05). Le dernier groupe comptait davantage de patients obèses (37,7% contre 32,6%, p < 0,001) et l'uricémie y était significativement plus élevée (485,5 ± 1,5 Μmol/l contre 465,0 ± 1,9 Μmol/l). Comme la goutte survenait à un âge plus jeune, nous avons appliqué une régression logistique multivariée et déterminé que des antécédents familiaux positifs, le sexe masculin, l'obésité, une uricémie élevée et la consommation de sodas sucrés étaient des facteurs prédictifs indépendants de goutte précoce. Conclusion: Les manifestations de la goutte en Chine ont évolué au cours des dix dernières années, avec notamment une tendance à une apparition plus précoce. © 2021

关键词： Apparition précoce Drop Early onset Facteurs de risque Goutte Risk factors

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DeCASA in AgriVerse: Parallel Agriculture for Smart Villages in Metaverses

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IEEE/CAA Journal of Automatica Sinica 2022年第12期9卷 2055-2062页

作者： Xiujuan Wang Mengzhen Kang Hequan Sun Philippe de Reffye Fei-Yue Wang The State Key Laboratory for Management and Control of Complex Systems Chinese Academy of SciencesBeijing 100190 Beijing Engineering Research Center of Intelligent Systems and Technology Beijing 100190China School of Artificial Intelligence University of Chinese Academy of SciencesBeijing 100190 Department of Chromosome Biology Max Planck Institute for Plant Breeding ResearchBeijing 100049China Faculty of Biology LMU MunichGroßhaderner Str.2Planegg-Martinsried D-82152Germany AMAP Univ MontpellierCIRADCNRSINRAEIRDMontpellier F-34398France IEEE Macao Institute of Systems Engineering Macao University of Science and TechnologyMacao 999078China

The demand for food is tremendously increasing with the growth of the world population,which necessitates the development of sustainable agriculture under the impact of various factors,such as climate *** fulfill this challenge,we are developing Metaverses for agriculture,referred to as Agri Verse,under our Decentralized complex Adaptive systems in Agriculture(De CASA)project,which is a digital world of smart villages created alongside the development of Decentralized Sciences(De Sci)and Decentralized Autonomous Organizations(DAO)for Cyber-Physical-Social systems(CPSSs).Additionally,we provide the architectures,operating modes and major applications of De CASA in *** achieving sustainable agriculture,a foundation model based on ACP theory and federated intelligence is ***,we discuss the challenges and opportunities.

关键词： Parallel Agriculture Management and control AgriVerse Agriculture CPSS ACP DAO-Based Platform Precision Agriculture

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A Novel YJQR-LSTM Model for Nonparametric Probabilistic Sustainable Agriculture Wind Power Forecasting Based on intelligent IoT

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IEEE Internet of Things Journal 2024年

作者： Wang, Jie Jiang, Junhui Chen, Xinlong Cai, Defu Wu, Yue Lu, Renzhi School of Artificial Intelligence and Automation Huazhong University of Science and Technology Wuhan430074 China Harbin Engineering University College of Computer Science and Technology Harbin150001 China State Grid Hubei Electric Power Research Institute Hubei Wuhan430079 China School of Technology State Key Laboratory of Efficient Production of Forest Resources Key Laboratory of National Forestry and Grassland Administration on Forestry Equipment and Automation Beijing Forestry University Beijing100083 China Key Laboratory of Image Processing and Intelligent Control School of Artificial Intelligence and Automation Huazhong University of Science and Technology Wuhan430074 China Key Laboratory of Industrial Internet of Things and Networked Control Ministry of Education Chongqing400065 China State Key Laboratory of Mechanical Transmission for Advanced Equipment Chongqing University Chongqing400044 China Hubei Key Laboratory of Advanced Control and Intelligent Automation for Complex Systems Wuhan430074 China

Energy costs associated with the consumption of non-renewable energy sources have become an important issue in improving the international competitiveness of agriculture. Wind power, as a renewable energy source, can replace non-renewable energy sources to reduce energy costs and improve the sustainability of agricultural. However, the inherent intermittency, randomness, and volatility within weather conditions and wind speed presents a substantial challenge in accurately predicting wind power generation. This work proposes a novel YJQR-LSTM algorithm that leverages Yeo-Johnson quantile regression (YJQR) with a long short-term memory (LSTM) network for nonparametric probabilistic forecasting of wind power generation via the intelligent Internet of Things. First, an improved YJQR model based on the YJ transformation is designed to obtain a more precise characterization of wind uncertainty, providing a more flexible probability density function for wind power generation. Then, utilizing the unique structure of the LSTM network to learn the parameters of the YJQR model, temporal features can be extracted from time series data. To mitigate the impact of outliers in the raw data on accuracy and improve computational efficiency, a novel logarithmic likelihood function is developed as the loss function utilized in the training phase. The effectiveness of the proposed algorithm is validated using a real-world dataset from five wind farms from the Global Energy Forecasting Competition. Numerical results demonstrate that the algorithm provides more accurate wind power prediction results in complex wind power data environments, which is important for making full use of wind energy and thus reducing the consumption of non-renewable energy in agriculture. © 2024 IEEE.

关键词： Wind forecasting

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Resource Scheduling Base on Bayesian Cramer-Rao Lower Bound for Multi-Target Tracking in Netted Colocated MIMO Radar systems

Resource Scheduling Base on Bayesian Cramer-Rao Lower Bound ...

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第40届中国控制会议

作者： Sijian Liao Zhihong Peng Junqi Cai School of Automation Beijing Institute of Technology China State Key Laboratory of Intelligent Control and Decision of Complex System

In this paper, an effective joint beam selection and power allocation（JBSPA） method is proposed to solve the online resource scheduling problem for multi-target tracking in distributed MIMO radar system. Overall target tracking performance can be improved by optimizing radar system beam selection and power allocation, since each MIMO radar can generate a timevarying beam, and adjust the quality of the observed signal by controlling the transmit power of each beam. In our method the feedback information of the target tracking period is used to complete the optimal radar-targets assignment and power allocation,the objective function is formulated based on the Bayesian Cramér-Rao lower bound, as the formulated JBSPA problem is nonconvex, a three steps solution method based on reward matrix is proposed to solve it effectively. Numerical results show that the proposed JBSPA method can deliver better performance than the competitors in overall MTT performance.

关键词： Resource Scheduling BCRLB Target Tracking Power Allocation MIMO Radar systems

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Efficient Multi-Robot Coverage of an Unknown Environment

Efficient Multi-Robot Coverage of an Unknown Environment

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第40届中国控制会议

作者： Zihao Chen Zhihong Peng Lei Jiao Yuanyuan Gui School of Automation Beijing Institute of Technology China State Key Laboratory of Intelligent Control and Decision of Complex System

This paper discusses the complete area coverage of multi-robots in unknown environments. Finding the optimal solution for the problem of area coverage with multiple robots has been proven to be NP-hard. This paper proposes the Multiagent Node Backtracking Area Coverage（MANBAC） algorithm, which uses improved BCD local area coverage method, and the node backtracking method that is based on the A* algorithm to achieve complete coverage of the entire unknown *** with the area coverage of a single robot, use multi robots can greatly improve the efficiency of area *** with the existing coverage algorithms in known area, this study can be applied to a wider range of area scenarios which are not known.

关键词： Area coverage Unknow environment Multirobot

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A novel hybrid neural network of fluid-structure interaction prediction for two cylinders in tandem arrangement

arXiv

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arXiv 2025年

作者： Lyu, Yanfang Zhang, Yunyang Gong, Zhiqiang Kang, Xiao Yao, Wen Pei, Yongmao State Key Laboratory for Turbulence and Complex Systems Center for Applied Physics and Technology College of Engineering Peking University Beijing100871 China Defense Innovation Institute Chinese Academy of Military Science Beijing100071 China Intelligent Game and Decision Laboratory Beijing100071 China Institute of Advanced Structure Technology Beijing Institute of Technology Beijing100081 China

Deep learning has shown promise in improving computing efficiency while ensuring modeling accuracy in fluid-structure interaction (FSI) analysis. However, its current capabilities are limited when it comes to constructing multi-object coupling systems with dynamic boundaries. To address such limitation, a novel FSI neural solver integrated by a fluid deep learning model with multi-time steps and a structural dynamic solver is proposed to accurately and reliably predict the vortex-induced vibration (VIV) evolution for two cylinders in tandem. This well-designed model in the form of end-to-end can precisely predict the instantaneous flow field state at the subsequent time by coupling the temporal flow fields of historical multi-time sequences and the current structural responses, moreover, derives the structural state at the next time. Furthermore, the novel fluid deep learning model consists of a wall shear model utilizing a multilayer perception network and flow field model with U-shaped architecture jointing the Fourier neural operator and modified convolution long-short term memory model. Both models effectively capture coupling transfer forces and predict instantaneous flow fields, with the latter demonstrating superior accuracy compared to Convolutional Neural Network- or Unet-based models with similar parameters. The prediction speed of the proposed models realizes an improvement of over 1000 times compared with the numerical simulation. Significantly, the proposed FSI neural model demonstrates exceptional capability in constructing the nonlinear complex multi-vibration systems and has substantial potential for advancing FSI modeling of flexible structures featuring pronounced nonlinear deformation boundaries. Copyright © 2025, The Authors. All rights reserved.

关键词： Hydraulics

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Cross-Membrane Penetration to Nucleus of Adherent Cells Using Micropipettes Made by Borosilicate Glass and Quartz 17

Cross-Membrane Penetration to Nucleus of Adherent Cells Usin...

引用

17th IEEE International Conference on Mechatronics and Automation, ICMA 2020

作者： Xu, Xinyue Liu, Xiaoming Lin, Yuqing Li, Pengyun Liu, Fengyu Tang, Xiaoqing Huang, Qiang Arai, Tatsuo Beijing Institute of Technology Key Laboratory of Biomimetic Robots and Systems Ministry of Education State Key Laboratory of Intelligent Control and Decision of Complex System Beijing Advanced Innovation Center for Intelligent Robots and Systems School of Mechatronical Engineering Beijing100081 China

ISBN: (纸本)9781728164151

In the biomicromanipulation field, single-cell manipulation is receiving attention due to its potential applications in many aspects of biomedicine. Cell injection, as a typical cell micromanipulation technique, is devoted to introducing foreign substances into living cells by penetrating a fine micropipette into cell membranes. Direct access to the intracellular environment, especially the nucleus, provides an ideal way to gain insight into the dynamic processes of living cells. This paper presents the comparison of controlled penetrations of two types of adherent cells and their nuclei by two types of micropipettes, made of borosilicate glass and quartz respectively. Due to the differences in the cell properties (e.g., height, adhesion strength), two corresponding penetration strategies optimizing the puncture angle and puncture height, are proposed to improve the success rate of the puncture process and the survival rate of cells after the puncture. Real nucleus puncture experiments adopting the optimal puncture strategy for each type of cells and carried out by a semi-automatic system, indicated a better puncture effect by quartz pipettes. Through this method, functional materials such as peptides and nanoparticles can be potentially introduced to perturb the cell activities and then realize its full automation. © 2020 IEEE.

关键词： Quartz

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Learning Pre-Grasp Manipulation of Flat Objects in Cluttered Environments using Sliding Primitives

Learning Pre-Grasp Manipulation of Flat Objects in Cluttered...

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IEEE International Conference on Robotics and Automation (ICRA)

作者： Jiaxi Wu Haoran Wu Shanlin Zhong Quqin Sun Yinlin Li State Key Laboratory of Turbulence and Complex Systems Intelligent Biomimetic Design Lab College of Engineering Peking University Beijing China Department of Automation University of Science and Technology of China Heifei China State Key Laboratory of Management and Control for Complex System Institute of Automation Chinese Academy of Science Beijing China Science and Technology on Thermal Energy and Power Laboratory Wuhan China

Flat objects with negligible thicknesses like books and disks are challenging to be grasped by the robot because of the width limit of the robot's gripper, especially when they are in cluttered environments. Pre-grasp manipulation is conducive to rearranging objects on the table and moving the flat objects to the table edge, making them graspable. In this paper, we formulate this task as Parameterized Action Markov decision Process, and a novel method based on deep reinforcement learning is proposed to address this problem by introducing sliding primitives as actions. A weight-sharing policy network is utilized to predict the sliding primitive's parameters for each object, and a Q-network is adopted to select the acted object among all the candidates on the table. Meanwhile, via integrating a curriculum learning scheme, our method can be scaled to cluttered environments with more objects. In both simulation and real-world experiments, our method surpasses the existing methods and achieves pre-grasp manipulation with higher task success rates and fewer action steps. Without fine-tuning, it can be generalized to novel shapes and household objects with more than 85% success rates in the real world. Videos and supplementary materials are available at https://***/view/pre-grasp-sliding.

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Visual Explanation of Object Detectors via Saliency Maps

Visual Explanation of Object Detectors via Saliency Maps

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IEEE Conference on Industrial Electronics and Applications (ICIEA)

作者： Jin Xiao Wenrui Liu Xiaoguang Hu Hao Jiang Weipeng Wang Li Yahang State Key Laboratory of Virtual Reality Technology and Systems Beihang University Beijing China Beihang University Beijing China The Third Academy of CASIC Beijing China Science and Technology on Complex System Control and Intelligent Agent Cooperation Laboratory Beijing China

In recent years, rapid progress of deep learning has resulted in object detection algorithms based on deep neural networks nearly completely replacing traditional methods. This shift has led to significant improvements in both accuracy and speed of object detection. However, deep neural networks that support decision-making inobject detection are complex black boxes with hidden internal logic and operations. This lack of transparency results in deep learning models being unexplainable, which limits their practical deployment. In this paper, we analyze the current state and future trends of interpretable technology in object detection and propose an effective object detection interpretable algorithm. This algorithm aims to explain the underlying logic of AI decision-making and provide support for the high performance and credibility of object detection algorithms based on deep neural networks through quantitative evaluation indicators.

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Boosting Black-Box Adversarial Attacks with Meta Learning

arXiv

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arXiv 2022年

作者： Fu, Junjie Sun, Jian Wang, Gang The State Key Lab of Intelligent Control and Decision of Complex Systems The School of Automation Beijing Institute of Technology Beijing100081 China Beijing Institute of Technology Chongqing Innovation Center Chongqing401120 China

Deep neural networks (DNNs) have achieved remarkable success in diverse fields. However, it has been demonstrated that DNNs are very vulnerable to adversarial examples even in black-box settings. A large number of black-box attack methods have been proposed to in the literature. However, those methods usually suffer from low success rates and large query counts, which cannot fully satisfy practical purposes. In this paper, we propose a hybrid attack method which trains meta adversarial perturbations (MAPs) on surrogate models and performs black-box attacks by estimating gradients of the models. Our method uses the meta adversarial perturbation as an initialization and subsequently trains any black-box attack method for several epochs. Furthermore, the MAPs enjoy favorable transferability and universality, in the sense that they can be employed to boost performance of other black-box adversarial attack methods. Extensive experiments demonstrate that our method can not only improve the attack success rates, but also reduces the number of queries compared to other methods. Copyright © 2022, The Authors. All rights reserved.

关键词： Deep neural networks

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