Enhanced sorption of inhibitory compounds from fermentation broth using a MOF@pseudo-DES composite

作     者：Honarmandrad, Zhila Khadem, Seyed Soroush Mousavi Kucharska, Karolina Kaykhaii, Massoud Luczak, Justyna Gebicki, Jacek 

作者机构：Department of Process Engineering and Chemical Technology Faculty of Chemistry Gdańsk University of Technology Narutowicza 11/12 Gdańsk80-233 Poland Comenius University in Bratislava Faculty of Natural Sciences Department of Analytical Chemistry Mlynská dolina Bratislava842 15 Slovakia  College of Sciences and Engineering University of Tasmania Private Bag 75 HobartTAS7001 Australia 

出 版 物：《Journal of Molecular Liquids》 (J Mol Liq)

年 卷 期：2025年第421卷

核心收录：

学科分类：07[理学] 0817[工学-化学工程与技术] 0806[工学-冶金工程] 0805[工学-材料科学与工程（可授工学、理学学位）] 0703[理学-化学] 070201[理学-理论物理] 0702[理学-物理学] 

基　　金：Research is funded by the National Science Centre Poland via OPUS grant no. UMO2021/41/B/ST8/02395 

主　　题：Hydrogen bonds 

摘      要：The increase in biorefinery processes underscores the need for effective biofuel generation;nevertheless, inhibitors such as hydroquinone (HQ), 5-hydroxymethylfurfural (HMF), furfural (FF), and vanillin (VAN) resulting from biomass degradation impede microbial growth and process efficiency. Herein, a deep eutectic solvent (DES)-like substance was in-situ generated on the surface of NH2-UiO-66 via a post-synthetic coating process using an amine-functionalized UiO-66 MOF and choline chloride (ChCl). ChCl, selected for its low cost and non-toxic properties as a hydrogen bond acceptor, enabled the formation of the thin layer of pseudo-DES on NH2-UiO-66 under solvent-free, thermal conditions, resulting in the composite material NH2-UiO-66@ pseudo-DES. The Zr6O4(OH)4 nodes and NH2 groups in NH2-UiO-66 are capable of forming robust hydrogen bonds with ChCl, enhancing the stability and functionality of the pseudo-DES coating. Various parameters influencing the removal efficiency, including pH, adsorbent amount, initial inhibitor concentration, and vortex time, were systematically investigated and optimized. Under the optimal conditions, the removal efficiency of HQ, HMF, FF, and VAN was 62.08%, 56.09%, 45.29%, and 83.46% respectively, for a synthetic sample. These values for real samples after hydrolysis and prior to fermentation were exceeded 51.73%, 53.21%, 42.69%, and 37.59%, for HQ, HMF, FF, and VAN, respectively. Inhibitor removal is driven by hydrogen bonding, electrostatic interactions, van der Waals forces, and π-π stacking with the inhibitors. This method demonstrates effective reusability for inhibitor removal up to four cycles. This groundbreaking research is the first of its kind to employ a MOF in conjunction with a pseudo-DES for this purpose;the results are simple, very effective, environmentally friendly, quick to react, and highly selective, making it ideal for biomass hydrolysis purification. © 2025 Elsevier B.V.