pasta: Pattern Analysis for Spatial Omics Data

作     者：Emons, Martin Gunz, Samuel Crowell, Helena L. Mallona, Izaskun Furrer, Reinhard Robinson, Mark D. 

作者机构：Department of Molecular Life Sciences SIB Swiss Institute of Bioinformatics University of Zurich Zurich Switzerland  Barcelona Spain Department of Mathematical Modeling and Machine Learning University of Zurich Zurich Switzerland 

出 版 物：《arXiv》 (arXiv)

年 卷 期：2024年

核心收录：

摘      要：Spatial omics assays allow for the molecular characterisation of cells in their spatial context. Notably, the two main technological streams, imaging-based and high-throughput sequencing-based, can give rise to very different data modalities. The characteristics of the two data types are well known in adjacent fields such as spatial statistics as point patterns and lattice data, and there is a wide range of tools available. This paper discusses the application of spatial statistics to spatially-resolved omics data and in particular, discusses various advantages, challenges, and nuances. This work is accompanied by a vignette, pasta, that showcases the usefulness of spatial statistics in biology using several R packages. © 2024, CC BY.