Amyloid-like fibrils derived from β-sheets of gp120 contribute to the neuronal pathology of HIV-associated neurocognitive disorders

作     者：Chan Yang Ruyu Wang Chen Cheng Jiaqi Yu Kunyu Lu Haobin Li Jinshen Wang Guodong Hu Hao Yang Jianfu He Hao Su Qingping Zhan Suiyi Tan Tong Zhang Shuwen Liu 

作者机构：Guangdong Provincial Key Laboratory of New Drug Screening NMPA Key Laboratory of Drug Metabolism Research and Evaluation School of Pharmaceutical Sciences Southern Medical University Guangzhou 510515 China. Department of Respiratory and Critical Care Medicine Institute of Respiratory and Critical Care Medicine the Tenth Affiliated Hospital of Southern Medical University Southern Medical University Guangdong 523059 China. Beijing Key Laboratory for HIV/AIDS Research Clinical and Research Center for Infectious Diseases Beijing Youan Hospital Capital Medical University Beijing 100069 China. Key Laboratory of Infectious Diseases Research in South China (Southern Medical University) Ministry of Education Guangzhou 510515 China. MOE Innovation Center for Medical Basic Research on Inflammation and Immune Related Diseases Southern Medical University Guangzhou 510515 China. 

出 版 物：《Acta pharmaceutica Sinica. B》 

年 卷 期：2025年第15卷第4期

页      面：2273-2277页

学科分类：1007[医学-药学(可授医学、理学学位)] 10[医学] 

主　　题：Amyloid peptides C–C chemokine receptors type 5 (CCR5) HIV-1 gp120 HIV-associated neurocognitive disorders (HAND) Neuropathology