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Systematic bioinformatic analysis of expression levels of 17,330 human genes across 9,783 samples from 175 types of healthy and pathological tissues

越过从 175 的 9,783 件样品的 17,330 人的基因的表示层次的系统的生物信息的分析健康、病理学的纸巾打字

作     者:Kilpinen, Sami Autio, Reija Ojala, Kalle Iljin, Kristiina Bucher, Elmar Sara, Henri Pisto, Tommi Saarela, Matti Skotheim, Rolf I. Bjorkman, Mari Mpindi, John-Patrick Haapa-Paananen, Saija Vainio, Paula Edgren, Henrik Wolf, Maija Astola, Jaakko Nees, Matthias Hautaniemi, Sampsa Kallioniemi, Olli 

作者机构:VTT Tech Res Ctr Turku Finland Univ Turku Turku Finland Univ Helsinki FIMM Helsinki Finland Tampere Univ Technol Dept Signal Proc FIN-33101 Tampere Finland Natl Hosp Norway Radiumhosp Inst Canc Res Dept Canc PreventMed Ctr NO-0310 Oslo Norway Univ Helsinki Scale Biol Res Program Inst Biomed & Genome Computat Syst Biol Lab FIN-00014 Helsinki Finland 

出 版 物:《GENOME BIOLOGY》 (基因组生物学)

年 卷 期:2008年第9卷第9期

页      面:R139-R139页

核心收录:

学科分类:0710[理学-生物学] 07[理学] 08[工学] 09[农学] 071007[理学-遗传学] 0901[农学-作物学] 0836[工学-生物工程] 090102[农学-作物遗传育种] 

基  金:Marie Curie Canceromics [MEXT-CT-2003-2728] EU, EU-EPITRON [LSHC-CT2005- 518417] Cancer Organizations of Finland Sigrid Juselius Foundation Turku TE-Centre Academy of Finland (SysBio) Centres of Excellence Emil Aaltonen Foundation Foundation of Technology Finnish Konkordia Fund and the Foundation 

主  题:Additional Data File Cancer Gene Malignant Peripheral Nerve Sheath Tumor Array Generation Cyclic Redundancy Check 

摘      要:Our knowledge on tissue- and disease-specific functions of human genes is rather limited and highly context-specific. Here, we have developed a method for the comparison of mRNA expression levels of most human genes across 9,783 Affymetrix gene expression array experiments representing 43 normal human tissue types, 68 cancer types, and 64 other diseases. This database of gene expression patterns in normal human tissues and pathological conditions covers 113 million datapoints and is available from the GeneSapiens website.

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