A comparison of prospective and retrospective assessments of diet in a study of colorectal cancer

作     者：Malila, N Virtanen, M Pietinen, P Virtamo, J Albanes, D Hartman, AM Heinonen, OP 

作者机构：Natl Publ Hlth Inst Helsinki Finland NCI Bethesda MD 20892 USA Univ Helsinki Dept Publ Hlth Helsinki Finland 

出 版 物：《NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL》 (营养与癌症)

年 卷 期：1998年第32卷第3期

页      面：146-153页

核心收录：

学科分类：12[管理学] 1204[管理学-公共管理] 120402[管理学-社会医学与卫生事业管理(可授管理学、医学学位)] 1004[医学-公共卫生与预防医学(可授医学、理学学位)] 1002[医学-临床医学] 10[医学] 

基　　金：NCI NIH HHS [N01-CN-45165] Funding Source: Medline 

主　　题：病例对照研究 结直肠肿瘤/病因学 膳食/统计学和数值数据 比值比 前瞻性研究 回顾性研究 危险因素 老年人 女(雌)性 人类 男(雄)性 中年人 

摘      要：Dietary factors are widely studied as risk factors for colorectal cancer, with much information from case-control studies. We evaluated the validity of dietary data from a retrospective case-control study of diet and colorectal cancer As part of the alpha-Tocopherol, beta-Carotene Cancer Prevention Study. diet was assessed at baseline and after diagnosis for colorectal cancer cases and at baseline and regularly during the trial for a random control group. The dietary assessment referred to the previous 12 months (in cases before diagnosis). In the two dietary assessments, the cases reported a greater increase in consumption of fruits and dairy products and a decrease in consumption of potatoes. Accordingly, relative risks for colorectal cancer by baseline dietary data differed markedly from odds ratios from case-control data;e.g., relative risk for a 652-mg increase in calcium intake was 0.79 (95% confidence interval = 0.48-1.30) in case-cohort analysis vs. an odds ratio of 1.57 (95% confidence interval = 1.06-2.33) for case-control analysis. The most likely explanation is the influence of current diet on recall of prediagnosis diet and effects of occult cancer on diet in the year before cancer diagnosis, which have implications fbr interpretation of case-control studies in evaluating associations between diet and colorectal cancer.