检索结果-内蒙古大学图书馆

The characteristics and analysis of the complete chloroplast genome ofHemerocalliscultivar Small orange lamp 2019 (Asphodelaceae)

引用

Mitochondrial DNA Part B 2024年第12期9卷

作者： Xiaofei Zhang Jiaming Yang xuwen Shang Shengyue Chai Lanling jiang Xiaolei Hou Zhenting Wang Lixin Lang a Liaoning Academy of Agricultural Sciences Institute of Flowers Shenyang China b Shenyang Agricultural University Shenyang China c China State Construction Corporation Limited Shenyang China

Hemerocalliscultivar Small orange lamp is a hybrid variety. Its whole chloroplast genome was 156,053 bp in size, consisting of 135 genes in total, including 89 mRNA genes, 38 tRNA genes, and 8 rRNA genes. The chloroplast genome contained a large single copy region (LSC 84,805 bp), a small single copy region (SSC 18,510 bp) and a pair of inverted repeats (IRa and IRb 26,369 bp). The overall GC content was 37.34%. Phylogenetic analysis showed thatHemerocallis lilioasphodelusandH. cultivar Small orange lamp are most closely related. This will provide valuable reference for further research on the genetic information of plants in theHemerocallis.

关键词： Chloroplast genome Asphodelaceae Hemerocallis cultivar Small orange lamp phylogenetic analysis

来源：评论

学校读者我要写书评

暂无评论

Quantitative isotopic fingerprinting of thallium associated with potentially toxic elements (PTEs) in fluvial sediment cores with multiple anthropogenic sources

引用

ENVIRONMENTAL POLLUTION 2020年第Part3期266卷 115252-115252页

作者： Liu, Juan Zhou, Yuchen She, Jingye Tsang, Daniel C. W. Lippold, Holger Wang, Jin jiang, Yanjun Wei, Xudong Yuan, Wenhuan Luo, xuwen Zhai, Shujing Song, Lan Guangzhou Univ Innovat Ctr Sch Environm Sci & Engn Inst Environm Res Greater Bay Guangzhou 510006 Peoples R China Minist Educ Key Lab Waters Qual & Conservat Pearl River Delta Guangzhou 510006 Peoples R China Hong Kong Polytech Univ Dept Civil & Environm Engn Kowloon Hung Hom Hong Kong Peoples R China Helmholtz Zentrum Dresden Rossendorf Inst Ressourcenokol D-04318 Leipzig Germany Fujian Normal Univ Sch Geog Sci Key Lab Humid Subtrop Ecogeog Proc Minist Educ Fuzhou Peoples R China Guangdong Prov Key Lab Radionuclides Pollut Contr Guangzhou 510006 Peoples R China Southern Univ Sci & Technol Sch Environm Sci & Engn Guangdong Prov Key Lab Soil & Groundwater Pollut Shenzhen 518055 Peoples R China

Thallium (Tl) is a dispersed trace metal showing remarkable toxicity. Various anthropogenic activities may generate Tl contamination in river sediments, posing tremendous risks to aquatic life and human health. This paper aimed to provide insight into the vertical distribution, risk assessment and source tracing of Tl and other potentially toxic elements (PTEs) (lead, cadmium, zinc and copper) in three representative sediment cores from a riverine catchment impacted by multiple anthropogenic activities (such as steel-making and Pb-Zn smelting). The results showed high accumulations of Tl combined with associated PTEs in the depth profiles. Calculations according to three risk assessment methods by enrichment factor (EF), geoaccumulation index (I-geo) and the potential ecological risk index (PERI) all indicated a significant contamination by Tl in all the sediments. Furthermore, lead isotopes were analyzed to fingerprint the contamination sources and to calculate their quantitative contributions to the sediments using the IsoSource software. The results indicated that a steel-making plant was the most important contamination source (similar to 56%), followed by a Pb-Zn smelter (similar to 20%). The natural parental bedrock was found to contribute similar to 24%. The findings highlight the importance of including multiple anthropogenic sources for quantitative fingerprinting of Tl and related metals by the lead isotopic approach in complicated environmental systems. (C) 2020 Elsevier Ltd. All rights reserved.

关键词： Thallium contamination Spatial distribution Pollution risk assessment Multiple end-members Isotopic tracing

来源：评论

学校读者我要写书评

暂无评论

Geochemistry and sources of hydrate-bound gas in the Shenhu area, northern south China sea: Insights from drilling and gas hydrate production tests

引用

JOURNAL OF PETROLEUM SCIENCE AND ENGINEERING 2022年第PartC期208卷 109459-109459页

作者： Liang, Qianyong Xiao, Xi Zhao, Jing Zhang, Wei Li, Yun Wu, Xuemin Ye, Jianliang Qin, xuwen Qiu, Haijun Liang, Jinqiang Lu, Jing'an Dong, Yifei Zhang, Tingting Xiong, Yongqiang jiang, Wenmin Guo, Binbin China Geol Survey Guangzhou Marine Geol Survey Guangzhou 510075 Peoples R China China Geol Survey Nat Gas Hydrate Engn Technol Ctr Guangzhou 510075 Peoples R China Southern Marine Sci & Engn Guangdong Lab Guangzho Guangzhou 511458 Peoples R China Chinese Acad Sci Guangzhou Inst Geochem State Key Lab Organ Geochem Guangzhou 510640 Peoples R China

Research on the origin and source of hydrate-bound gas and its relationship to deep conventional oil and gas accumulation in a basin is critical to understanding the accumulation mechanism of gas hydrates and to resource evaluation of gas hydrate accumulation. In this study, the hydrate-bound gas obtained via pressure coring and the production gas recovered during a production test on a gas hydrate reservoir in the Shenhu area offshore of Southern China were tested and discussed. The geochemical analysis results indicate that methane is the predominant gas, and heavier hydrocarbons (C2+) are also present but in low concentrations. The molecular compositions of the hydrate gas recovered from two production test sites are similar to those of the hydrate-bound gas acquired via pressure coring. In addition to the isotopic composition of the methane, the carbon and hydrogen isotopes of the C2+ hydrocarbons were obtained for the first time. The delta C-13 isotopes of the methane range from -66.6 parts per thousand to -46.2 parts per thousand, indicating that the hydrate-bound gases have a mixed origin, containing both biogenic and thermogenic gases. The plot of delta C-13(1) versus delta C-13(2) suggests that the biogenic and thermogenic hydrocarbons were derived from marine organic matter and terrestrial organic matter, respectively. The isotopic characterization of the hydrate-bound gas reveals that the thermogenic hydrate gas contains both humic-type gas and sapropel-type gas, but the sapropel-type gas is predominant. The source rocks of the thermogenic hydrate gas are interpreted to be both the gas-prone coal measure strata of the Enping Formation and the oil-prone medium-deep lacustrine strata of the Wenchang Formation, the latter of which contributed more to the hydrocarbon supply of the gas hydrates. In addition, the maturity of the source rocks of the thermogenic hydrate gas may be lower than that of the deeply buried conventional hydrocarbons discovered in the Ba

关键词： Gas hydrates Pressure core Production test Hydrate-bound gas Source rocks Migration Shenhu area Northern South China Sea

来源：评论

学校读者我要写书评

暂无评论

基于混流生产模式的装配车间物料配送路径规划方法

引用

现代制造工程 2021年第7期 109-116页

作者：王昀睿赵旭雯武争利蒋子强西安科技大学机械工程学院西安710054

合理规划物料配送路径能够提升车间生产效率,降低车间物流成本和生产成本。针对混流装配车间配送不及时、费用高等问题,提出基于混流生产模式的物料配送路径规划方法。以工位为物料配送对象,对混流装配车间物料配送环境进行分析,找出混... 详细信息

合理规划物料配送路径能够提升车间生产效率,降低车间物流成本和生产成本。针对混流装配车间配送不及时、费用高等问题,提出基于混流生产模式的物料配送路径规划方法。以工位为物料配送对象,对混流装配车间物料配送环境进行分析,找出混流装配线的物料消耗规律,明确物料配送数量,简化物料配送过程。在此基础上,结合生产实际的时间窗约束,以最小化物料配送总费用为目标建立了物料配送模型,采用改进蚁群算法对该模型进行求解,最后以某视频控制卡混流装配车间为实例,验证了该方法的可行性和有效性。

关键词：混流装配物料配送路径规划蚁群算法

来源：评论

学校读者我要写书评

暂无评论

Synthesis and bioactivity of 1,3-thiazolidine-2-thione derivatives against type III secretion system of Xanthomonas oryzae

引用

BIOORGANIC & MEDICINAL CHEMISTRY 2019年第15期27卷 3364-3371页

作者： Tao, Hui Tian, Hao jiang, Shan Xiang, xuwen Ahmed, Wasim Tang, Riyuan Cui, Zi-Ning South China Agr Univ Integrat Microbiol Res Ctr State Key Lab Conservat & Utilizat Subtrop Agrobi Guangdong Prov Key Lab Microbial Signals & Dis Co Guangzhou 510642 Guangdong Peoples R China South China Agr Univ Dept Appl Chem Coll Mat & Energy Guangzhou 510642 Guangdong Peoples R China

Targeting virulence factors of bacterial without affecting their growth and survival, has been an initiative strategy for the development of novel anti-microbial agents. The type III secretion system (T3SS), one of essential and highly conserved virulence factors in most Gram-negative pathogenic bacteria, has been regarded as an effective target that developed new anti-microbial drugs. Xanthomonas oryzae pv. oryzae (Xoo) is one of the most important bacterial pathogens on rice, which causes leaf blight disease. To discover potential anti-virulence agents against the pathogens, a new series of 1,3-thiazolidine-2-thione derivatives containing 5-phenyl-2-furan were designed and synthesized. Their structures were characterized by H-1 NMR, C-13 NMR, MS, and elemental analysis. All the title compounds inhibited the promoter activity of a harpin gene hpa1, significantly, that were further checked for the impact on bacterial growth. The results indicated that treatment of Xoo with the title compound III-7 did not affect bacterial growth or survival. Moreover, quantitative reverse transcription-polymerase chain reaction (qRT-PCR) analysis showed that the expression of the Xoo T3SS was suppressed by treatment with the inhibitor. The mRNA levels of representative genes in the hrp (hypersensitive response and pathogenicity) cluster, as well as the regulatory genes hrpG and hrpX, were reduced. Finally, the in vivo test demonstrated that the compounds could reduce the disease symptoms of Xoo on the rice cultivar (Oryza sativa) IR24.

关键词： Xanthomonas oryzae pv. oryzae (Xoo) Type III secretion system (T3SS) Small molecule inhibitors Virulence factors 1,3-Thiazolidine-2-thione

来源：评论

学校读者我要写书评

暂无评论

Molecular Dynamics Simulation of the Interaction between Common Metal Ions and Humic Acids

引用

WATER 2020年第11期12卷 3200-3200页

作者： Wu, Xu Xia, Yu Yuan, Lianhua Xia, Kaiyu jiang, Yu Li, Na He, xuwen China Univ Min & Technol Beijing Sch Chem & Environm Engn Beijing 100083 Peoples R China

Humic acids (HAs) have important environmental and geochemical effects on soil, water environments and sediment. HAs strongly complex some metal ions, which affects the migration of metal ions and the colloidal aggregation of HA. Here, the complexation of Ca2+ and Mg2+ with HA in aqueous solution under neutral conditions has been systematically studied by molecular dynamics (MD) simulation. The results show that the aggregation of HA is caused by the complexation of HA and metal ions, mainly due to the intermolecular bridging between Ca2+, Mg2+ and COO- groups. Monodentate and bidentate coordinations have been found between Ca2+ and COO- groups of different HA molecules in the same simulation system. Mg2+ only has a monodentate coordination with COO- group.

关键词： humic acids metal ions aggregation molecular dynamics simulation

来源：评论

学校读者我要写书评

暂无评论

含1,3,4-噻(噁)二唑吩嗪-1-甲酰胺类衍生物的合成与杀菌活性

引用

农药学学报 2021年第2期23卷 287-295页

作者：何敏古景文李司丞向绪稳姜珊崔紫宁亚热带农业生物资源保护与利用国家重点实验室群体微生物研究中心广东省微生物信号与作物病害防控重点实验室植物保护学院华南农业大学广州510642 岭南现代农业科学与技术广东省实验室广州510642

对广泛存在于链霉菌和铜绿假单胞菌中的一种天然活性物质——申嗪霉素进行了结构修饰,合成了一系列高活性的含1,3,4-噻(噁)二唑的申嗪霉素衍生物I1~I28。杀菌活性测定结果表明:所有目标化合物对禾谷镰刀菌具有较好的杀菌活性,均明显优... 详细信息

对广泛存在于链霉菌和铜绿假单胞菌中的一种天然活性物质——申嗪霉素进行了结构修饰,合成了一系列高活性的含1,3,4-噻(噁)二唑的申嗪霉素衍生物I1~I28。杀菌活性测定结果表明:所有目标化合物对禾谷镰刀菌具有较好的杀菌活性,均明显优于母体申嗪霉素。离体杀菌活性测定结果显示,化合物I_(8)(EC_(50)=33.25μg/mL)和化合物I22(EC_(50)=46.52μg/mL)对禾谷镰刀菌的杀菌活性是申嗪霉素(EC_(50)=128.54μg/mL)的3~4倍。活体杀菌活性显示,在500μg/mL质量浓度下,化合物I_(8)(58.69%)和化合物I22(55.37%)对禾谷镰刀菌的抑制率是申嗪霉素(25.14%)的两倍。构效关系分析结果表明,在苯环上引入吸电子基团对化合物的活性不利;而引入给电子基团则有利于提高其杀菌活性。同时,同一取代基在苯环上的取代位置依据活性的高低排列顺序为:邻位>对位>间位。这些结果可用于指导该类化合物的进一步结构改造。

关键词：吩嗪-1-甲酸 1 3 4-噻二唑 1 3 4-噁二唑杀菌活性

来源：评论

学校读者我要写书评

暂无评论

恙虫病临床特征及重症恙虫病的早期诊断

引用

热带病与寄生虫学 2023年第6期21卷 321-325页

作者：李翔马仲序李国忠姜建杰付旭文张乐云南省传染性疾病临床医学中心昆明市第三人民医院

目的了解恙虫病临床特征，探讨重症恙虫病诊断的早期临床指征。方法收集昆明市第三人民医院2017年1月至2021年12月恙虫病确诊患者的临床资料、胸部CT影像学及实验室检查结果；将恙虫病患者分为非重症恙虫病组（简称非重症组）与重症... 详细信息

目的了解恙虫病临床特征，探讨重症恙虫病诊断的早期临床指征。方法收集昆明市第三人民医院2017年1月至2021年12月恙虫病确诊患者的临床资料、胸部CT影像学及实验室检查结果；将恙虫病患者分为非重症恙虫病组（简称非重症组）与重症恙虫病组（简称重症组），利用logistic回归法分析重症恙虫病的早期临床指征。结果研究共纳入恙虫病患者181例，其中非重症组104例，重症组77例。所有患者均发现皮肤焦痂，最常见于躯干，占47.5%（86/181）。患者均出现发热，其他临床表现为头痛、咳嗽、腹痛、肌肉酸痛和呼吸困难。胸部CT影像表明，所有患者胸腔积液的发生率为49.7%（90/181），重症组和非重症组发生率分别为67.5%（52/77）和36.5%（38/104），差异有统计学意义（χ2=17.001,P<0.05）。实验室检查中，重症组外周血中性粒细胞绝对值、谷草转氨酶、C反应蛋白、降钙素原、乳酸脱氢酶、D-二聚体及白细胞介素-6水平高于非重症组，外周血血小板计数低于非重症组，差异均有统计学意义（Z=2.858、-3.870、-5.937、-6.546、-4.153、-4.802、-5.119、-5.039,P均<0.05）。回归分析结果表明，血清谷草转氨酶、降钙素原、白细胞介素-6升高以及存在胸腔积液与重症恙虫病发生有相关性；受试者工作特征曲线（receiver operating characteristic curve,ROC）曲线下面积为0.839，其敏感度为62.3%，特异度为96.2%。结论患者出现发热伴随皮肤焦痂应考虑恙虫病的可能，血清谷草转氨酶、降钙素原、白细胞介素-6升高和胸部CT显示胸腔积液可作为考虑恙虫病发展为重症的早期指标，应予以关注，对有重症倾向的患者及早诊治，以期降低病死率。

关键词：恙虫病立克次体临床特征重症病例早期诊断

来源：评论

学校读者我要写书评

暂无评论

日本电力现货市场运行现状及对中国的启示

引用

全球能源互联网 2021年第5期4卷 497-505页

作者：杨素肖汉雄王阳蒋宇丁羽刘胥雯孙燕一国网能源研究院有限公司北京市昌平区102209 国网江苏省电力有限公司江苏省南京市210008

日本新一轮电力体制改革启动以后,现货市场的交易量大幅提升,市场结构也逐渐完善,对中国电力现货市场建设有较大的借鉴意义。深入分析日本电力现货市场的结构和运行规律,包括日前市场、日内市场和平衡机制。对改革后市场主体、市场价格... 详细信息

日本新一轮电力体制改革启动以后,现货市场的交易量大幅提升,市场结构也逐渐完善,对中国电力现货市场建设有较大的借鉴意义。深入分析日本电力现货市场的结构和运行规律,包括日前市场、日内市场和平衡机制。对改革后市场主体、市场价格、交易量等进行逐年变化趋势分析。总结改革过程中出现的问题和日本的解决方式,最后提出对中国电力市场建设的启示和建议。

关键词：日本电力市场现货市场日前市场日内市场平衡机制

来源：评论

学校读者我要写书评

暂无评论

Smart hypoxia-responsive transformable and charge-reversible nanoparticles for the deep penetration and tumor microenvironment modulation of pancreatic cancer

引用

BIOMATERIALS 2022年第0期287卷 000-000页

作者： Chen, Hongyi Guo, Qin Chu, Yongchao Li, Chao Zhang, Yiwen Liu, Peixin Zhao, Zhenhao Wang, Yu Luo, Yifan Zhou, Zheng Zhang, Tongyu Song, Haolin Li, xuwen Li, Chufeng Su, Boyu You, Haoyu Sun, Tao jiang, Chen Fudan Univ Key Lab Smart Drug Delivery State Key Lab Med Neurobiol Dept PharmaceutSch PharmInst Brain SciMinist Ed Shanghai 201203 Peoples R China Fudan Univ Inst Brain Sci MOE Frontiers Ctr Brain Sci Sch PharmDept Pharmaceut Shanghai 201203 Peoples R China

The compact extracellular matrix (ECM) of pancreatic ductal adenocarcinoma (PDAC) is the major physical barrier that hinders the delivery of anti-tumor drugs, leading to strong inherent chemotherapy resistance as well as establishing an immunosuppressive tumor microenvironment (TME). However, forcibly destroying the stroma barrier would break the balance of delicate signal transduction and dependence between tumor cells and matrix components. Uncontrollable growth and metastasis would occur, making PDAC more difficult to control. Hence, we design and construct an aptamer-decorated hypoxia-responsive nanoparticle s(DGL)(n)@Apt co-loading gemcitabine monophosphate and STAT3 inhibitor HJC0152. This nanoparticle can reverse its surficial charge in the TME, and reduce the size triggered by hypoxia. The released ultra-small DGL particles loading gemcitabine monophosphate exhibit excellent deep-tumor penetration, chemotherapy drugs endocytosis promotion, and autophagy induction ability. Meanwhile, HJC0152 inhibits overactivated STAT3 in both tumor cells and tumor stroma, softens the stroma barrier, and reeducates the TME into an immune-activated state. This smart code -livery strategy provides an inspiring opportunity in PDAC treatment.

关键词： Hypoxia-responsive Sizereduction Chargereversal Deeppenetration TMEmodulation

来源：评论

学校读者我要写书评

暂无评论

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

请选择保存的检索档案：

请选择收藏分类：

通借通还

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：