Purpose: To compare the preloading effect of 500 ml hydroxyethylstarch (HES) 10% with IL Lactated Ringer's solution (LR). Methods: In 40 healthy women undergoing elective Cesarean section HES, 500 ml (n = 20), or ...
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Purpose: To compare the preloading effect of 500 ml hydroxyethylstarch (HES) 10% with IL Lactated Ringer's solution (LR). Methods: In 40 healthy women undergoing elective Cesarean section HES, 500 ml (n = 20), or LR, IL (n = 20), was administered during 10 min before spinal anesthesia. The incidence of hypotension, (systolic blood pressure < 80% of baseline and < 100 mm Hg), and the amount of ephedrine used to treat it were compared. Also, the incidence of nausea and/or vomiting were recorded. Neonatal outcome was assessed using Apgar scores and umbilical venous and arterial blood gases. Results: The incidence of hypotension was higher in the LR than in HES group (80% vs 40%), Mean minimum systolic blood pressure was lower in the LR than in the HES group (86.1 +/- 12.7 mm Hg vs 99.6 +/- 9.7 mm Hg P < 0.05). Systolic blood pressure < 90 mmHg occurred in two of 20 patients (10%) who received HES vs 11 of 20 patients (55%) who received LR (P < 0.05). More doses of ephedrine were required to treat hypotension in the LR than in the HES group (35.3 +/- 18.4 mg vs 10.6 +/- 8.6 mg;P < 0.05), The incidence of nausea and/or vomiting was lower in the HES than in the crystalloid group. Neonatal outcome was good and similar in both groups. Conclusion: Preloading patients undergoing elective Cesarean section with 500 mi HES 10%, decreases the incidence and severity of spinal-induced hypotension more than preloading with IL of LR solution.
Purpose: To compare preservative-free 1% lignocaine with balanced salt solution (BSS(R)) in alleviating pain during hydrodissection in phacoemulsification cataract surgery. Setting: West Norwich Hospital, Norfolk, Uni...
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Purpose: To compare preservative-free 1% lignocaine with balanced salt solution (BSS(R)) in alleviating pain during hydrodissection in phacoemulsification cataract surgery. Setting: West Norwich Hospital, Norfolk, United Kingdom. Methods: This prospective double-masked trial comprised 68 patients having a day-case phacoemulsification cataract surgery. Patients were randomly divided into 2 groups, receiving either BSS or lignocaine 1% solution for hydrodissection during routine uneventful phacoemulsification using topical anesthesia. The level of intraoperative pain was scored on a scale of 0 (no pain) to 10 (severe pain), and the scores between the 2 groups were compared. Results: Of the 68 patients, 33 (49%) received BSS and 35 (51%), lignocaine 1% solution. A pain score greater than 2 was considered clinically significant;28 patients (85%) in the BSS group and 25 (71%) in the lignocaine 1% group scored 2 or less. The chi-square and Mann-Whitney tests found no significant difference between the BSS and lignocaine 1% groups (P = .30 and P = .432, respectively). Conclusion: There was no significant difference in the pain scores in patients who received BSS or lignocaine 1% solution. Thus, we conclude that hydrodissecting with lignocaine 1% solution does not provide added pain relief during phacoemulsification. J Cataract Refract Surg 2000;26:733-735 (C) 2000 ASCRS and ESCRS.
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