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检索条件"主题词=Bnip3"
513 条 记 录,以下是51-60 订阅
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Increased bnip3 activity contributes to mitochondrial dysregulation: A hypothesis on the mechanism of ineffective erythropoiesis in β-thalassemia
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MEDICAL HYPOTHESES 2024年 189卷 111395-111395页
作者: Noulsri, Egarit Lerdwana, Surada Mahidol Univ Fac Med Res Div Siriraj Hosp Bangkok Thailand Mahidol Univ Fac Med Dept Res Biomed Res Incubator UnitSiriraj Hosp Bangkok Thailand
Ineffective erythropoiesis (IE) and the premature destruction of erythroblasts play important roles in the pathophysiology of 8-thalassemia. Accumulating evidence suggests that the pathology of IE is associated with m... 详细信息
来源: 评论
HDAC6 preserves bnip3 expression and mitochondrial integrity by deacetylating p53 at lysine 320
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BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 2024年 691卷 149320页
作者: Lee, Se-In Seo, Yuri Oanh, Hoang Thi Vo, Thi Tuyet Hanh Go, Hyeonbin Kim, Myung hun Lee, Joo-Yong Chungnam Natl Univ Grad Sch Analyt Sci & Technol GRAST Daejeon 305764 South Korea Korea Basic Sci Inst Daejeon 305806 South Korea Chungnam Natl Univ GRAST 99 Daehak Ro Daejeon 305764 South Korea
HDAC6 has been reported as a deacetylase of p53 at multiple lysine residues, associated with the canonical functions of p53, such as apoptosis and tumor suppression. We have previously reported that p53 acetylation at... 详细信息
来源: 评论
bnip3 as a new tool to promote healthy brain aging
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AGING CELL 2024年 第2期23卷 e14042-e14042页
作者: Neikirk, Kit Marshall, Andrea G. Santisteban, Monica M. Hinton Jr, Antentor Vanderbilt Univ Dept Mol Physiol & Biophys 750 Robinson Res Bldg2200 Pierce Ave Nashville TN 37232 USA Vanderbilt Univ Med Ctr Dept Med Nashville TN USA
The article "Neuronal induction of bnip3-mediated mitophagy slows systemic aging in Drosophila" reveals BCL2-interacting protein 3 as a therapeutic target to counteract brain aging and prolong overall organi... 详细信息
来源: 评论
Fangji Huangqi decoction ameliorates membranous nephropathy through the upregulation of bnip3-mediated mitophagy
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JOURNAL OF ETHNOPHARMACOLOGY 2024年 324卷 117734页
作者: Wang, Yuxin Ma, Yuhua Ke, Yanrong Jiang, Xiaocheng Liu, Jian Xiao, Yang Zheng, Hong Wang, Chaojun Chen, Xue Shi, Manman Tradit Chinese Med Hosp Kunshan Dept Nephrol Kunshan 215300 Jiangsu Peoples R China Shanghai Jiao Tong Univ Ruijin Hosp Sch Med Dept Nephrol Shanghai Peoples R China Nanjing Univ Chinese Med Nanjing Jiangsu Peoples R China
Ethnopharmacological relevance: Fangji Huangqi Decoction (FJHQ), a traditional Chinese medicinal formula outlined in Zhang Zhongjing's "Jin Gui Yao Lue" during the Han Dynasty, is often used to treat con... 详细信息
来源: 评论
The evolutionarily conserved hif-1/bnip3 pathway promotes mitophagy and mitochondrial fission in crustacean testes during hypoxia
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AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY, INTEGRATIVE AND COMPARATIVE PHYSIOLOGY 2023年 第1期324卷 R128-R142页
作者: Zhao, Qianqian Sun, Xichao Zheng, Cheng Xue, Cheng Jin, Yiting Zhou, Na Sun, Shengming Shanghai Ocean Univ Key Lab Freshwater Aquat Resources Minist Agr & Rural Affairs Shanghai Peoples R China Shanghai Ocean Univ Minist Sci & Technol Int Res Ctr Marine Biosci Shanghai Peoples R China Macau Univ Sci & Technol State Key Lab Qual Res Chinese Med Macau Peoples R China Macau Univ Sci & Technol Sch Pharm Macau Peoples R China
The hypoxia-inducible factor 1 (HIF-1) cascade is an ancient and strongly evolutionarily conserved signaling pathway that is involved in the hypoxic responses of most metazoans. Despite immense advances in the underst... 详细信息
来源: 评论
Astragalus polysaccharide ameliorates steroid-induced osteonecrosis of femoral head through miR-206/HIF-1α/bnip3 axis
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KAOHSIUNG JOURNAL OF MEDICAL SCIENCES 2021年 第12期37卷 1089-1100页
作者: Zhang, Shen-Yao Wang, Fan Zeng, Xiang-Jing Huang, Zhen Dong, Ke-Fang Hunan Univ Chinese Med Dept Orthoped Affiliated Hosp 2 233 CAIERs North Rd Changsha 410005 Peoples R China
Declining autophagy and rising apoptosis are the main factors driving the development of steroid-induced osteonecrosis of the femoral head (SONFH). Here, we showed that astragalus polysaccharide (APS) improved femoral... 详细信息
来源: 评论
Acid ground nano-realgar processed product inhibits breast cancer by inducing mitophagy via the p53/bnip3/NIX pathway
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JOURNAL OF CELLULAR AND MOLECULAR MEDICINE 2023年 第22期27卷 3478-3490页
作者: Fang, Jiahui Zou, Xue Gong, Ling Xi, Juan Liu, Yi Yang, Xiaoli Zhang, Xiuqiao Gui, Chun Hubei Univ Chinese Med Coll Pharm Wuhan Hubei Peoples R China Hubei Univ Med Taihe Hosp Dept Pharm Shiyan Hubei Peoples R China Hubei Univ Chinese Med Coll Inspection Wuhan Hubei Peoples R China Hubei Univ Chinese Med Coll Pharm 16 Huangjiahu West Rd Wuhan 430065 Hubei Peoples R China
Breast cancer is a highly prevalent malignancy with the first morbidity and the primary reason for female cancer-related deaths worldwide. Acid ground nano-realgar processed product (NRPP) could inhibit breast cancer ... 详细信息
来源: 评论
The interaction between adhesion protein 33 (TvAP33) and bnip3 mediates the adhesion and pathogenicity of Trichomonas vaginalis to host cells
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PARASITES & VECTORS 2023年 第1期16卷 210-210页
作者: Zhang, Zhenchao Deng, Yangyang Sheng, Wanxin Song, Xiaoxiao Li, Yuhua Li, Fakun Pan, Ying Tian, Xiaowei Yang, Zhenke Wang, Shuai Wang, Mingyong Mei, Xuefang Xinxiang Med Univ Sch Basic Med Sci Dept Pathogen Biol Xinxiang 453003 Henan Peoples R China Xinxiang Med Univ Sch Basic Med Sci Xinxiang Key Lab Pathogen Biol Xinxiang 453003 Henan Peoples R China Xinxiang Med Univ Affiliated Hosp 3 Xinxiang 453003 Henan Peoples R China Xinxiang Med Univ Sch Lab Med Xinxiang Key Lab Immunoregulat & Mol Diagnost Xinxiang 453003 Peoples R China Shangqiu Med Coll Sch Med Technol Shangqiu 476100 Peoples R China
Background Trichomonas vaginalis is a widespread and important sexually transmitted pathogen. Adherence to the surface of the host cell is the precondition for the parasitism and pathogenicity of this parasite. Tricho... 详细信息
来源: 评论
bnip3 as a potential target of esculetin for treating ovarian cancer and prognostic biomarker in ovarian cancer patients
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European Journal of Pharmacology 2025年 999卷 177698页
作者: Fan, Wen Zhang, Yongjun Yang, Xiangqun Liu, Zhenyan Wu, Xingyan Li, Lvzhou Zhao, Taoyu Li, Haoran Liu, Xiaolin Cui, Daolei Wan, Qianqian Li, Wenliang Yang, Hongying Zhang, Hongping Jia, Yue Department of Gynecology The Third Affiliated Hospital of Kunming Medical University Yunnan Cancer Hospital Kunming 650118 China Department of Obstetrics and Gynecology Dehong Affiliated Hospital of Kunming Medical University Dehong People's Hospital of Yunnan Province Dehong 678400 China Medical School Kunming University of Science and Technology Kunming 650500 China Department of Gastroenterology Shanghai Municipal Hospital of Traditional Chinese Medicine Shanghai University of Traditional Chinese Medicine Shanghai 200071 China Institute of Environmental Remediation and Human Health School of Ecology and Environment Southwest Forestry University Kunming 650224 China Medical Affairs Department The First Affiliated Hospital of Yunnan University of Traditional Chinese Medicine Kunming 650021 China
Among gynecological tumors, ovarian cancer has the highest mortality rate and worst prognosis. Therefore, it is crucial to identify and develop novel methods and targets for treating ovarian cancer. Previous studies h... 详细信息
来源: 评论
bnip3 as a potential biomarker for the identification of prognosis and diagnosis in solid tumours
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MOLECULAR CANCER 2023年 第1期22卷 143-143页
作者: Yu, Qin Fu, Wenhao Fu, Yutang Ye, Wenjing Yan, Huiqiong Yu, Zecheng Li, Ruirui Cai, Yili Chen, Yuxin Wang, Lingyun Wei, Xianqiao Chen, Yangkun Zhang, Yuheng Ying, Huazhong Tang, Furong Dai, Fangwei Han, Wei Hangzhou Med Coll Sch Informat Engn Hangzhou Zhejiang Peoples R China Hangzhou Med Coll Sch Med Imaging Hangzhou Zhejiang Peoples R China Hangzhou Med Coll Ctr Lab Anim Hangzhou 310013 Zhejiang Peoples R China Hangzhou Med Coll Zhejiang Prov Key Lab Lab Anim & Safety Res Hangzhou 310013 Zhejiang Peoples R China Hangzhou Med Coll Sch Clin Med Hangzhou Zhejiang Peoples R China Hangzhou Med Coll Sch Med Lab & Biol Engn Hangzhou Zhejiang Peoples R China Hangzhou Med Coll Engn Res Ctr Novel Vaccine Zhejiang Prov Hangzhou Zhejiang Peoples R China Wenzhou Med Univ Quzhou Peoples Hosp Quzhou Affiliated Hosp Quzhou Zhejiang Peoples R China Tsinghua Univ Sch Med Dept Basic Med Sci Beijing Peoples R China
Background Traditional radiotherapy and chemotherapy have been intensively studied for their role in the treatment of tumours. However, these therapies often cause side effects for patients, which calls for the develo... 详细信息
来源: 评论